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ONTOLOGY REPORT - ANNOTATIONS

Term:synapse pruning
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Accession:GO:0098883 term browser browse the term
Definition:A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
Synonyms:exact_synonym: synapse clearance;   synapse disassembly;   synapse elimination;   synapse removal

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synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in ISO (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chrNW_004624764:7,363,615...7,366,408
Ensembl chrNW_004624764:7,363,567...7,366,617 		JBrowse link
G C1qb complement C1q B chain involved_in ISO (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chrNW_004624764:7,377,013...7,382,953
Ensembl chrNW_004624764:7,376,967...7,383,445 		JBrowse link
G C1qc complement C1q C chain involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624764:7,369,365...7,373,238
Ensembl chrNW_004624764:7,369,338...7,373,436 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISO (PMID:21778362) UniProt PMID:21778362 NCBI chrNW_004624731:1,705,953...1,719,452
Ensembl chrNW_004624731:1,706,043...1,719,452 		JBrowse link
G Epha4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624823:3,555,273...3,697,794
Ensembl chrNW_004624823:3,555,288...3,698,990 		JBrowse link
complement-mediated synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in ISO (PMID:18083105) ARUK-UCL PMID:18083105 NCBI chrNW_004624764:7,363,615...7,366,408
Ensembl chrNW_004624764:7,363,567...7,366,617 		JBrowse link
G C3 complement C3 involved_in ISO (PMID:18083105) ARUK-UCL PMID:18083105 NCBI chrNW_004624828:3,773,816...3,798,077
Ensembl chrNW_004624828:3,770,221...3,797,946 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:22632727) ARUK-UCL PMID:22632727 NCBI chrNW_004624782:14,316,505...14,367,841
Ensembl chrNW_004624782:14,318,499...14,367,922 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) UniProt PMID:30548312 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29752066) ARUK-UCL PMID:29752066 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
positive regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:33097708) ARUK-UCL PMID:33097708 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
regulation of excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk13 potassium two pore domain channel subfamily K member 13 involved_in ISO (PMID:34642249) UniProt PMID:34642249 NCBI chrNW_004624734:12,206,237...12,319,321
Ensembl chrNW_004624734:12,207,094...12,317,720 		JBrowse link
regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb3 adhesion G protein-coupled receptor B3 involved_in ISO (PMID:25611509) SynGO PMID:25611509 NCBI chrNW_004624753:26,284,931...26,980,937
Ensembl chrNW_004624753:26,287,621...26,980,325 		JBrowse link
G C1ql1 complement C1q like 1 involved_in ISO (PMID:25611509) SynGO PMID:25611509 NCBI chrNW_004624795:363,947...368,885
Ensembl chrNW_004624795:363,942...369,441 		JBrowse link
G Cdk5 cyclin dependent kinase 5 involved_in ISO PMID:17143272 SynGO PMID:17143272 RGD:8554385 NCBI chrNW_004624800:5,562,468...5,566,458
Ensembl chrNW_004624800:5,562,462...5,569,937 		JBrowse link
G Epha4 EPH receptor A4 involved_in ISO PMID:17143272 SynGO PMID:17143272 RGD:8554385 NCBI chrNW_004624823:3,555,273...3,697,794
Ensembl chrNW_004624823:3,555,288...3,698,990 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISO (PMID:24831527) SynGO PMID:24831527 NCBI chrNW_004624805:8,748,848...8,800,259
Ensembl chrNW_004624805:8,765,949...8,802,149 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624843:5,558,053...5,648,869
Ensembl chrNW_004624843:5,557,839...5,648,871 		JBrowse link
G Plxnc1 plexin C1 involved_in ISO (PMID:24831527) SynGO PMID:24831527 NCBI chrNW_004624750:12,639,292...12,777,237
Ensembl chrNW_004624750:12,641,674...12,777,702 		JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624786:974,785...1,001,810
Ensembl chrNW_004624786:974,876...997,956 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624794:841,302...867,717
Ensembl chrNW_004624794:841,247...867,708 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17650
    cellular process 17226
      cellular component organization or biogenesis 7005
        cellular component organization 6802
          cell junction organization 911
            synapse organization 659
              synapse pruning 17
                complement-mediated synapse pruning 4
                excitatory synapse pruning + 2
                negative regulation of synapse pruning + 0
                positive regulation of synapse pruning 1
                regulation of synapse pruning + 11
paths to the root