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ONTOLOGY REPORT - ANNOTATIONS

Term:synapse pruning
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Accession:GO:0098883 term browser browse the term
Definition:A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
Synonyms:exact_synonym: synapse clearance;   synapse disassembly;   synapse elimination;   synapse removal


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synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement component 1, q subcomponent, alpha polypeptide involved_in IGI (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114 		JBrowse link
G C1qb complement component 1, q subcomponent, beta polypeptide involved_in IGI (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chr 4:136,607,437...136,613,511
Ensembl chr 4:136,607,440...136,613,498 		JBrowse link
G C1qc complement component 1, q subcomponent, C chain involved_in IGI (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chr 4:136,617,115...136,620,225
Ensembl chr 4:136,617,115...136,620,376 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IMP (PMID:21778362) UniProt PMID:21778362 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,877,749...119,898,945 		JBrowse link
G Epha4 Eph receptor A4 involved_in IMP
EXP
IDA		 (PMID:12496762) SynGO PMID:12496762 NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725 		JBrowse link
complement-mediated synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement component 1, q subcomponent, alpha polypeptide involved_in IMP (PMID:18083105) ARUK-UCL PMID:18083105 NCBI chr 4:136,623,227...136,626,155
Ensembl chr 4:136,623,228...136,626,114 		JBrowse link
G C3 complement component 3 involved_in IMP (PMID:18083105) ARUK-UCL PMID:18083105 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Itgam integrin alpha M involved_in IMP (PMID:22632727) ARUK-UCL PMID:22632727 NCBI chr 7:127,661,812...127,717,663
Ensembl chr 7:127,661,812...127,717,663 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IMP (PMID:30548312) UniProt PMID:30548312 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IMP (PMID:29752066) ARUK-UCL PMID:29752066 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
positive regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO
ISS		 GO_Central
ARUK-UCL		 GO_REF:0000024 GO_REF:0000119 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
regulation of excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk13 potassium channel, subfamily K, member 13 involved_in IMP (PMID:34642249) UniProt PMID:34642249 NCBI chr12:99,928,132...100,028,941
Ensembl chr12:99,930,758...100,028,941 		JBrowse link
regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb3 adhesion G protein-coupled receptor B3 involved_in IMP
IDA		 (PMID:25611509) SynGO PMID:25611509 NCBI chr 1:25,106,557...25,869,338
Ensembl chr 1:25,106,557...25,868,788 		JBrowse link
G C1ql1 complement component 1, q subcomponent-like 1 involved_in IMP
IDA		 (PMID:25611509) SynGO PMID:25611509 NCBI chr11:102,830,090...102,837,542
Ensembl chr11:102,830,090...102,837,514 		JBrowse link
G Cd47 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) involved_in IEP
IDA
IMP		 (PMID:30308165) SynGO PMID:30308165 NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373 		JBrowse link
G Cdk5 cyclin dependent kinase 5 involved_in ISO GO_Central GO_REF:0000096 NCBI chr 5:24,612,595...24,628,737
Ensembl chr 5:24,623,239...24,628,528 		JBrowse link
G Epha4 Eph receptor A4 involved_in IEA
ISO		 Ensembl
GO_Central		 GO_REF:0000096 GO_REF:0000107 NCBI chr 1:77,343,819...77,491,763
Ensembl chr 1:77,343,822...77,491,725 		JBrowse link
G Itgb1 integrin beta 1 (fibronectin receptor beta) involved_in IDA
IMP		 (PMID:24831527) SynGO PMID:24831527 NCBI chr 8:129,412,135...129,460,060
Ensembl chr 8:129,412,135...129,459,681 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor involved_in IEP
IDA
IMP		 (PMID:17143272) SynGO PMID:17143272 NCBI chr 1:87,404,551...87,501,661
Ensembl chr 1:87,404,556...87,501,592 		JBrowse link
G Plxnc1 plexin C1 involved_in IDA
IMP		 (PMID:24831527) SynGO PMID:24831527 NCBI chr10:94,626,728...94,780,875
Ensembl chr10:94,626,728...94,780,697 		JBrowse link
G Sarm1 sterile alpha and HEAT/Armadillo motif containing 1 involved_in IDA
IMP		 (PMID:22678360) SynGO PMID:22678360 NCBI chr11:78,361,099...78,388,642
Ensembl chr11:78,363,156...78,388,580 		JBrowse link
G Vangl2 VANGL planar cell polarity 2 involved_in IMP
IDA		 (PMID:34407949) SynGO PMID:34407949 NCBI chr 1:171,828,527...171,856,532
Ensembl chr 1:171,828,527...171,856,011 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28640
    cellular process 18404
      cellular component organization or biogenesis 7348
        cellular component organization 7137
          cell junction organization 993
            synapse organization 704
              synapse pruning 18
                complement-mediated synapse pruning 4
                excitatory synapse pruning + 2
                negative regulation of synapse pruning + 0
                positive regulation of synapse pruning 1
                regulation of synapse pruning + 12
paths to the root