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ONTOLOGY REPORT - ANNOTATIONS

Term:synapse pruning
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Accession:GO:0098883 term browser browse the term
Definition:A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
Synonyms:exact_synonym: synapse clearance;   synapse disassembly;   synapse elimination;   synapse removal


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synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QA complement C1q A chain involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678 		JBrowse link
G C1QB complement C1q B chain involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637 		JBrowse link
G C1QC complement C1q C chain involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:22,643,633...22,648,108
Ensembl chr 1:22,643,014...22,648,110 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in TAS (PMID:20920788) ARUK-UCL PMID:20920788 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 involved_in IC
IEA
ISS		 ARUK-UCL
Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 GO_REF:0000111 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735 		JBrowse link
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in TAS (PMID:24449494) ParkinsonsUK-UCL PMID:24449494 NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:221,418,027...221,574,202
Ensembl chr 2:221,418,027...221,574,202 		JBrowse link
complement-mediated synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QA complement C1q A chain involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678 		JBrowse link
G C3 complement C3 involved_in IEA
ISS		 Ensembl
ARUK-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G ITGAM integrin subunit alpha M involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA		 ARUK-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
positive regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IMP (PMID:33097708) ARUK-UCL PMID:33097708 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
regulation of excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNK13 potassium two pore domain channel subfamily K member 13 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:90,061,994...90,185,853
Ensembl chr14:90,061,994...90,185,853 		JBrowse link
regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB3 adhesion G protein-coupled receptor B3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:68,635,282...69,389,506
Ensembl chr 6:68,635,282...69,390,571 		JBrowse link
G C1QL1 complement C1q like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:44,959,693...44,968,303
Ensembl chr17:44,959,693...44,968,303 		JBrowse link
G CD47 CD47 molecule involved_in ISO (PMID:30308165) SynGO PMID:30308165 NCBI chr 3:108,043,091...108,091,031
Ensembl chr 3:108,043,091...108,091,862 		JBrowse link
G CDK5 cyclin dependent kinase 5 involved_in ISO PMID:17143272 SynGO PMID:17143272 RGD:8554385 NCBI chr 7:151,053,815...151,057,897
Ensembl chr 7:151,053,815...151,057,897 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:221,418,027...221,574,202
Ensembl chr 2:221,418,027...221,574,202 		JBrowse link
G ITGB1 integrin subunit beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792 		JBrowse link
G NGEF neuronal guanine nucleotide exchange factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:232,878,701...233,013,256
Ensembl chr 2:232,878,701...233,013,256 		JBrowse link
G PLXNC1 plexin C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:94,148,577...94,307,675
Ensembl chr12:94,148,577...94,307,675 		JBrowse link
G SARM1 sterile alpha and TIR motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,371,694...28,404,049
Ensembl chr17:28,364,356...28,404,049 		JBrowse link
G VANGL2 VANGL planar cell polarity protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:160,400,564...160,428,670
Ensembl chr 1:160,400,564...160,428,678 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27210
    cellular process 19786
      cellular component organization or biogenesis 7754
        cellular component organization 7522
          cell junction organization 1015
            synapse organization 734
              synapse pruning 20
                complement-mediated synapse pruning 4
                excitatory synapse pruning + 2
                negative regulation of synapse pruning + 0
                positive regulation of synapse pruning 1
                regulation of synapse pruning + 12
paths to the root