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ONTOLOGY REPORT - ANNOTATIONS

Term:synapse pruning
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Accession:GO:0098883 term browser browse the term
Definition:A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
Synonyms:exact_synonym: synapse clearance;   synapse disassembly;   synapse elimination;   synapse removal

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synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QA complement C1q A chain involved_in ISO (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chr20:110,024,847...110,027,868 JBrowse link
G C1QB complement C1q B chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:110,003,036...110,011,317
Ensembl chr20:110,002,864...110,011,316 		JBrowse link
G C1QC complement C1q C chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:110,016,355...110,021,123
Ensembl chr20:110,016,362...110,020,854 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:136,757...153,316
Ensembl chr15:150,718...151,785 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:107,344,442...107,501,375
Ensembl chr10:107,352,530...107,499,788 		JBrowse link
complement-mediated synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QA complement C1q A chain involved_in ISO (PMID:18083105) ARUK-UCL PMID:18083105 NCBI chr20:110,024,847...110,027,868 JBrowse link
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,250,422...6,289,264 JBrowse link
G ITGAM integrin subunit alpha M involved_in ISO (PMID:22632727) ARUK-UCL PMID:22632727 NCBI chr 5:27,957,162...28,042,697
Ensembl chr 5:27,957,324...28,042,691 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) UniProt PMID:30548312 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29752066) ARUK-UCL PMID:29752066 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
positive regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
regulation of excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNK13 potassium two pore domain channel subfamily K member 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:67,782,523...67,912,950
Ensembl chr24:67,781,977...67,913,195 		JBrowse link
regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB3 adhesion G protein-coupled receptor B3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:5,543,587...6,287,255
Ensembl chr17:5,543,556...6,000,742 		JBrowse link
G C1QL1 complement C1q like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:61,436,164...61,444,059
Ensembl chr16:61,436,418...61,443,567 		JBrowse link
G CD47 CD47 molecule involved_in ISO (PMID:30308165) SynGO PMID:30308165 NCBI chr22:72,702,236...72,749,344
Ensembl chr22:72,702,324...72,751,887 		JBrowse link
G CDK5 cyclin dependent kinase 5 involved_in ISO PMID:17143272 SynGO PMID:17143272 RGD:8554385 NCBI chr21:119,235,687...119,240,163 JBrowse link
G EPHA4 EPH receptor A4 involved_in ISO PMID:17143272 SynGO PMID:17143272 RGD:8554385 NCBI chr10:107,344,442...107,501,375
Ensembl chr10:107,352,530...107,499,788 		JBrowse link
G ITGB1 integrin subunit beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:32,201,030...32,258,247
Ensembl chr 9:32,202,204...32,258,154 		JBrowse link
G NGEF neuronal guanine nucleotide exchange factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:118,911,019...118,959,259 JBrowse link
G PLXNC1 plexin C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:89,549,312...89,701,890 JBrowse link
G SARM1 sterile alpha and TIR motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:22,137,990...22,163,431
Ensembl chr16:22,138,588...22,162,893 		JBrowse link
G VANGL2 VANGL planar cell polarity protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,521,066...3,549,301
Ensembl chr20:3,521,060...3,548,718 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19829
    cellular process 19347
      cellular component organization or biogenesis 8804
        cellular component organization 8578
          cell junction organization 939
            synapse organization 676
              synapse pruning 18
                complement-mediated synapse pruning 4
                excitatory synapse pruning + 2
                negative regulation of synapse pruning + 0
                positive regulation of synapse pruning 1
                regulation of synapse pruning + 12
paths to the root