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ONTOLOGY REPORT - ANNOTATIONS

Term:synapse pruning
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Accession:GO:0098883 term browser browse the term
Definition:A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
Synonyms:exact_synonym: synapse clearance;   synapse disassembly;   synapse elimination;   synapse removal

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synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in ISO (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chrNW_004955452:2,753,362...2,756,220
Ensembl chrNW_004955452:2,752,970...2,756,488 		JBrowse link
G C1qb complement C1q B chain involved_in ISO (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chrNW_004955452:2,765,844...2,771,695
Ensembl chrNW_004955452:2,769,752...2,772,534 		JBrowse link
G C1qc complement C1q C chain involved_in ISO (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chrNW_004955452:2,759,079...2,762,522
Ensembl chrNW_004955452:2,758,821...2,762,522 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISO (PMID:21778362) UniProt PMID:21778362 NCBI chrNW_004955427:24,691,206...24,705,599
Ensembl chrNW_004955427:24,701,073...24,707,230 		JBrowse link
G Epha4 EPH receptor A4 involved_in ISO (PMID:12496762) SynGO PMID:12496762 NCBI chrNW_004955453:12,099,800...12,240,199
Ensembl chrNW_004955453:12,099,757...12,240,199 		JBrowse link
complement-mediated synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in ISO (PMID:18083105) ARUK-UCL PMID:18083105 NCBI chrNW_004955452:2,753,362...2,756,220
Ensembl chrNW_004955452:2,752,970...2,756,488 		JBrowse link
G C3 complement C3 involved_in ISO (PMID:18083105) ARUK-UCL PMID:18083105 NCBI chrNW_004955495:2,796,601...2,824,233
Ensembl chrNW_004955495:2,796,663...2,824,697 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:22632727) ARUK-UCL PMID:22632727 NCBI chrNW_004955493:8,116,886...8,160,806
Ensembl chrNW_004955493:8,116,834...8,260,759 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) UniProt PMID:30548312 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29752066) ARUK-UCL PMID:29752066 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
positive regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:33097708) ARUK-UCL PMID:33097708 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697 		JBrowse link
regulation of excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk13 potassium two pore domain channel subfamily K member 13 involved_in ISO (PMID:34642249) UniProt PMID:34642249 NCBI chrNW_004955438:12,522,063...12,660,078
Ensembl chrNW_004955438:12,522,737...12,663,480 		JBrowse link
regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb3 adhesion G protein-coupled receptor B3 involved_in ISO (PMID:25611509) SynGO PMID:25611509 NCBI chrNW_004955488:3,803,859...4,509,043
Ensembl chrNW_004955488:3,806,695...4,508,421 		JBrowse link
G C1ql1 complement C1q like 1 involved_in ISO (PMID:25611509) SynGO PMID:25611509 NCBI chrNW_004955451:17,729,106...17,734,657 JBrowse link
G Cd47 CD47 molecule involved_in ISO (PMID:30308165) SynGO PMID:30308165 NCBI chrNW_004955427:8,704,519...8,740,962 JBrowse link
G Cdk5 cyclin dependent kinase 5 involved_in ISO PMID:17143272 SynGO PMID:17143272 RGD:8554385 NCBI chrNW_004955491:5,491,744...5,497,280
Ensembl chrNW_004955491:5,491,744...5,497,280 		JBrowse link
G Epha4 EPH receptor A4 involved_in ISO PMID:17143272 SynGO PMID:17143272 RGD:8554385 NCBI chrNW_004955453:12,099,800...12,240,199
Ensembl chrNW_004955453:12,099,757...12,240,199 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISO (PMID:24831527) SynGO PMID:24831527 NCBI chrNW_004955462:4,454,809...4,483,227
Ensembl chrNW_004955462:4,454,809...4,484,842 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor involved_in ISO (PMID:17143272) SynGO PMID:17143272 NCBI chrNW_004955453:3,082,826...3,186,039
Ensembl chrNW_004955453:3,082,628...3,186,039 		JBrowse link
G Plxnc1 plexin C1 involved_in ISO (PMID:24831527) SynGO PMID:24831527 NCBI chrNW_004955405:30,885,277...31,023,947
Ensembl chrNW_004955405:30,885,278...31,021,544 		JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 involved_in ISO (PMID:22678360) SynGO PMID:22678360 NCBI chrNW_004955481:4,743,458...4,763,766
Ensembl chrNW_004955481:4,743,458...4,763,766 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 involved_in ISO (PMID:34407949) SynGO PMID:34407949 NCBI chrNW_004955468:12,162,084...12,189,322
Ensembl chrNW_004955468:12,161,843...12,189,547 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12619
    cellular process 12054
      cellular component organization or biogenesis 5425
        cellular component organization 5295
          cell junction organization 862
            synapse organization 636
              synapse pruning 18
                complement-mediated synapse pruning 4
                excitatory synapse pruning + 2
                negative regulation of synapse pruning + 0
                positive regulation of synapse pruning 1
                regulation of synapse pruning + 12
paths to the root