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ONTOLOGY REPORT - ANNOTATIONS

Term:synapse pruning
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Accession:GO:0098883 term browser browse the term
Definition:A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
Synonyms:exact_synonym: synapse clearance;   synapse disassembly;   synapse elimination;   synapse removal


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synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1QA complement C1q A chain involved_in ISO (PMID:27033548) ARUK-UCL PMID:27033548 NCBI chr 1:21,821,927...21,825,020 JBrowse link
G C1QB complement C1q B chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,838,514...21,846,855
Ensembl chr 1:22,786,685...22,797,581 		JBrowse link
G C1QC complement C1q C chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:21,828,969...21,833,518
Ensembl chr 1:22,770,582...22,782,176 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:39,158,346...39,176,604
Ensembl chr 3:39,440,955...39,457,219 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790 		JBrowse link
complement-mediated synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C3 complement C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:5,708,211...5,753,178
Ensembl chr19:6,629,287...6,674,699 		JBrowse link
G ITGAM integrin subunit alpha M involved_in ISO (PMID:22632727) ARUK-UCL PMID:22632727 NCBI chr16:23,634,476...23,707,147
Ensembl chr16:31,630,146...31,702,406 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
positive regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
regulation of excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNK13 potassium two pore domain channel subfamily K member 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:70,678,256...70,803,575
Ensembl chr14:90,032,219...90,154,687 		JBrowse link
regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB3 adhesion G protein-coupled receptor B3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:66,484,739...67,238,607
Ensembl chr 6:69,788,604...70,536,820 		JBrowse link
G C1QL1 complement C1q like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:12,354,791...12,363,101
Ensembl chr17:12,525,552...12,535,286 		JBrowse link
G CD47 CD47 molecule involved_in ISO (PMID:30308165) SynGO PMID:30308165 NCBI chr 3:105,170,246...105,217,603
Ensembl chr 3:112,104,037...112,143,522 		JBrowse link
G CDK5 cyclin dependent kinase 5 involved_in ISO PMID:17143272 SynGO PMID:17143272 RGD:8554385 NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499 		JBrowse link
G EPHA4 EPH receptor A4 involved_in ISO PMID:17143272 SynGO PMID:17143272 RGD:8554385 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790 		JBrowse link
G ITGB1 integrin subunit beta 1 involved_in ISO (PMID:24831527) SynGO PMID:24831527 NCBI chr10:33,023,573...33,081,384
Ensembl chr10:33,608,978...33,644,031 		JBrowse link
G NGEF neuronal guanine nucleotide exchange factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:120,110,441...120,153,934
Ensembl chr2B:239,027,286...239,155,874 		JBrowse link
G PLXNC1 plexin C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:91,694,449...91,852,950
Ensembl chr12:95,093,332...95,251,249 		JBrowse link
G SARM1 sterile alpha and TIR motif containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,370,206...28,403,440
Ensembl chr17:28,878,498...28,905,363 		JBrowse link
G VANGL2 VANGL planar cell polarity protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:135,754,897...135,783,031
Ensembl chr 1:139,683,745...139,704,281 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18871
      cellular component organization or biogenesis 8571
        cellular component organization 8365
          cell junction organization 916
            synapse organization 664
              synapse pruning 18
                complement-mediated synapse pruning 3
                excitatory synapse pruning + 2
                negative regulation of synapse pruning + 0
                positive regulation of synapse pruning 1
                regulation of synapse pruning + 12
paths to the root