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ONTOLOGY REPORT - ANNOTATIONS

Term:synapse pruning
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Accession:GO:0098883 term browser browse the term
Definition:A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared.
Synonyms:exact_synonym: synapse clearance;   synapse disassembly;   synapse elimination;   synapse removal


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synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in ISO UniProtKB:P14106|UniProtKB:Q02105 (PMID:27033548) RGD PMID:27033548 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C1qb complement C1q B chain involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P98086|UniProtKB:Q02105 (PMID:27033548)		 Ensembl
RGD		 PMID:27033548 GO_REF:0000107 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407 		JBrowse link
G C1qc complement C1q C chain involved_in ISO UniProtKB:P14106|UniProtKB:P98086 (PMID:27033548) RGD PMID:27033548 NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21778362)		 UniProt
RGD		 PMID:21778362 GO_REF:0000024 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Epha4 Eph receptor A4 involved_in ISO (PMID:12496762) RGD PMID:12496762 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
complement-mediated synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain involved_in IEA
ISO		 GO_REF:0000107
(PMID:18083105)		 Ensembl
RGD		 PMID:18083105 GO_REF:0000107 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534 		JBrowse link
G C3 complement C3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18083105)		 Ensembl
RGD		 PMID:18083105 GO_REF:0000107 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Itgam integrin subunit alpha M involved_in ISO (PMID:22632727) RGD PMID:22632727 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30548312) RGD PMID:30548312 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29752066) RGD PMID:29752066 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
positive regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:33097708) RGD PMID:33097708 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of excitatory synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnk13 potassium two pore domain channel subfamily K member 13 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:34642249)		 UniProt
Ensembl
RGD		 PMID:34642249 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:119,240,825...119,345,292
Ensembl chr 6:119,242,188...119,345,240 		JBrowse link
regulation of synapse pruning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb3 adhesion G protein-coupled receptor B3 involved_in ISO (PMID:25611509) RGD PMID:25611509 NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855 		JBrowse link
G C1ql1 complement C1q like 1 involved_in ISO (PMID:25611509) RGD PMID:25611509 NCBI chr10:87,902,125...87,909,556
Ensembl chr10:87,902,137...87,909,310 		JBrowse link
G Cd47 Cd47 molecule involved_in ISO (PMID:30308165) RGD PMID:30308165 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 involved_in IDA
IMP
EXP		 PMID:17143272 SynGO PMID:17143272 PMID:17143272 PMID:17143272 RGD:8554385, RGD:8554385, RGD:8554385 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Epha4 Eph receptor A4 involved_in IMP
IEP
EXP
IDA		 PMID:17143272 SynGO PMID:17143272 PMID:17143272 PMID:17143272 PMID:17143272 RGD:8554385, RGD:8554385, RGD:8554385, RGD:8554385 NCBI chr 9:78,815,460...78,958,139
Ensembl chr 9:78,815,460...78,958,139 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24831527)		 Ensembl
RGD		 PMID:24831527 GO_REF:0000107 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Ngef neuronal guanine nucleotide exchange factor involved_in ISO (PMID:17143272) RGD PMID:17143272 NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914 		JBrowse link
G Plxnc1 plexin C1 involved_in ISO (PMID:24831527) RGD PMID:24831527 NCBI chr 7:29,390,038...29,543,985
Ensembl chr 7:29,390,048...29,543,779 		JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 involved_in ISO (PMID:22678360) RGD PMID:22678360 NCBI chr10:63,369,456...63,393,016
Ensembl chr10:63,369,456...63,392,822 		JBrowse link
G Vangl2 VANGL planar cell polarity protein 2 involved_in ISO (PMID:34407949) RGD PMID:34407949 NCBI chr13:84,462,731...84,489,404
Ensembl chr13:84,465,527...84,489,378 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20537
    cellular process 19526
      cellular component organization or biogenesis 7187
        cellular component organization 6903
          cell junction organization 985
            synapse organization 705
              synapse pruning 18
                complement-mediated synapse pruning 4
                excitatory synapse pruning + 2
                negative regulation of synapse pruning + 0
                positive regulation of synapse pruning 1
                regulation of synapse pruning + 12
paths to the root