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ONTOLOGY REPORT - ANNOTATIONS

Term:synaptic vesicle lumen acidification
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Accession:GO:0097401 term browser browse the term
Definition:The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
Synonyms:exact_synonym: synaptic vesicle lumen pH reduction;   synaptic vesicle proton loading


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synaptic vesicle lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP1 ATPase H+ transporting accessory protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:122,133,314...122,140,949
Ensembl chr  X:122,133,325...122,140,447 		JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in ISO (PMID:28793259) SynGO PMID:28793259 NCBI chr  X:35,050,588...35,073,633
Ensembl chr  X:35,050,606...35,073,067 		JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,422,144...20,486,459
Ensembl chr 9:20,423,373...20,484,328 		JBrowse link
G ATP6V0A4 ATPase H+ transporting V0 subunit a4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:9,864,938...9,949,740
Ensembl chr16:9,885,149...9,949,708 		JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,519,869...38,525,217
Ensembl chr 6:38,520,765...38,525,062 		JBrowse link
G ATP6V0D1 ATPase H+ transporting V0 subunit d1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:81,926,589...81,965,959
Ensembl chr 5:81,926,612...81,965,526 		JBrowse link
G ATP6V0E2 ATPase H+ transporting V0 subunit e2 involved_in ISO (PMID:28793259) SynGO PMID:28793259 NCBI chr16:14,642,090...14,646,956
Ensembl chr16:14,642,200...14,646,145 		JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:18,038,143...18,103,649
Ensembl chr33:18,038,801...18,101,435 		JBrowse link
G ATP6V1B1 ATPase H+ transporting V1 subunit B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:69,261,311...69,287,540
Ensembl chr10:69,252,926...69,287,542 		JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:36,833,246...36,858,846
Ensembl chr25:36,834,196...36,858,819 		JBrowse link
G ATP6V1C1 ATPase H+ transporting V1 subunit C1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:4,509,699...4,569,500
Ensembl chr13:4,510,003...4,579,846 		JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:41,332,581...41,354,058
Ensembl chr 8:41,333,021...41,354,320 		JBrowse link
G ATP6V1E1 ATPase H+ transporting V1 subunit E1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:45,222,647...45,249,317 JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:7,786,841...7,789,584
Ensembl chr14:7,786,844...7,789,548 		JBrowse link
G ATP6V1G1 ATPase H+ transporting V1 subunit G1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:68,755,586...68,760,863 JBrowse link
G ATP6V1G2 ATPase H+ transporting V1 subunit G2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:1,046,109...1,049,839
Ensembl chr12:1,046,732...1,050,103 		JBrowse link
G ATP6V1G3 ATPase H+ transporting V1 subunit G3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:4,368,476...4,388,544
Ensembl chr 7:4,368,418...4,388,539 		JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:5,381,693...5,544,062
Ensembl chr29:5,260,175...5,508,960 		JBrowse link
G CLCN3 chloride voltage-gated channel 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21378974) Ensembl
MGI		 PMID:21378974 GO_REF:0000107 NCBI chr25:20,528,708...20,616,687
Ensembl chr25:20,528,699...20,615,070 		JBrowse link
G SLC17A7 solute carrier family 17 member 7 acts_upstream_of_or_within ISO (PMID:19169251) MGI PMID:19169251 NCBI chr 1:107,054,242...107,064,444
Ensembl chr 1:107,054,410...107,063,550 		JBrowse link
regulation of synaptic vesicle lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC9A6 solute carrier family 9 member A6 involved_in ISO PMID:33372133 SynGO PMID:33372133 RGD:405650253 NCBI chr  X:106,408,789...106,465,504
Ensembl chr  X:106,398,850...106,463,252 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22117
    homeostatic process 1988
      cellular homeostasis 966
        neuron cellular homeostasis 78
          synaptic vesicle lumen acidification 21
            negative regulation of synaptic vesicle lumen acidification 0
            positive regulation of synaptic vesicle lumen acidification 0
            regulation of synaptic vesicle lumen acidification + 1
Path 2
Term Annotations click to browse term
  biological_process 22117
    localization 5642
      establishment of localization 4983
        transport 4625
          transmembrane transport 1718
            monoatomic ion transmembrane transport 1101
              monoatomic cation transmembrane transport 926
                proton transmembrane transport 172
                  synaptic vesicle lumen acidification 21
                    negative regulation of synaptic vesicle lumen acidification 0
                    positive regulation of synaptic vesicle lumen acidification 0
                    regulation of synaptic vesicle lumen acidification + 1
paths to the root