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ONTOLOGY REPORT - ANNOTATIONS

Term:apoptotic signaling pathway
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Accession:GO:0097190 term browser browse the term
Definition:The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
Comment:This term can be used to annotate gene products involved in apoptotic events happening downstream of the cross-talk point between the extrinsic and intrinsic apoptotic pathways. The cross-talk starts when caspase-8 cleaves Bid and truncated Bid interacts with mitochondria. From this point on it is not possible to distinguish between extrinsic and intrinsic pathways.
Synonyms:exact_synonym: apoptotic signalling pathway;   induction of apoptosis by extracellular signals
 alt_id: GO:0008624
 xref: Reactome:R-HSA-193681 "Ceramide signalling";   Reactome:R-HSA-204998 "Cell death signalling via NRAGE, NRIF and NADE";   Reactome:R-HSA-75157 "FasL/ CD95L signaling"


show annotations for term's descendants           Sort by:
apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor type 1C involved_in ISO
IEA
IMP		 (PMID:15150278)
GO_REF:0000107
PMID:15107418		 RGD
Ensembl		 PMID:15150278 PMID:15107418 GO_REF:0000107, RGD:408345206 NCBI chr 3:63,224,322...63,301,252
Ensembl chr 3:42,822,610...42,892,327 		JBrowse link
G Adora2a adenosine A2a receptor acts_upstream_of ISO
IEA		 MGI:2155985 (PMID:10845921)
GO_REF:0000107		 RGD
Ensembl		 PMID:10845921 GO_REF:0000107 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Anxa6 annexin A6 involved_in IEA
ISO
IBA		 GO_REF:0000107
(PMID:23341998)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:23341998 GO_REF:0000033 GO_REF:0000107 NCBI chr10:39,602,106...39,657,183
Ensembl chr10:39,097,109...39,156,433 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within ISO MGI:2675966|MGI:3029528 (PMID:11717309), (PMID:12931191), (PMID:15231831) RGD PMID:11717309 PMID:12931191 PMID:15231831 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO
IEA		 (PMID:15901672)
GO_REF:0000107		 RGD
Ensembl		 PMID:15901672 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 ISO
IEA
ISS		 (PMID:16424160)
GO_REF:0000107
MGI:1857429 (PMID:12925707), (PMID:14507967)
MGI:2675387 (PMID:18436203)
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12925707 PMID:14507967 PMID:16424160 PMID:18436203 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO (PMID:11463392) RGD PMID:11463392 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bbln bublin coiled coil protein acts_upstream_of_or_within ISO (PMID:32569872) RGD PMID:32569872 NCBI chr 3:36,072,325...36,075,070
Ensembl chr 3:15,674,580...15,677,374 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in ISO
IEA		 (PMID:22267217)
GO_REF:0000107		 RGD
Ensembl		 PMID:22267217 GO_REF:0000107 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of ISO
IEA		 MGI:99161 (PMID:11290297)
GO_REF:0000107		 RGD
Ensembl		 PMID:11290297 GO_REF:0000107 NCBI chr17:86,240,683...86,250,044
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of ISO (PMID:17367784) RGD PMID:17367784 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in ISO
IEA		 (PMID:22267217)
GO_REF:0000107		 RGD
Ensembl		 PMID:22267217 GO_REF:0000107 NCBI chr 3:29,569,907...29,578,402
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within ISO
IEA		 (PMID:12477715), (PMID:16183742)
GO_REF:0000107		 RGD
Ensembl		 PMID:12477715 PMID:16183742 GO_REF:0000107 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11101870)
GO_REF:0000107
(PMID:16183742)		 RGD
Ensembl		 PMID:11101870 PMID:16183742 GO_REF:0000107 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp8ap2 caspase 8 associated protein 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:47,014,667...47,052,275 		JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:21382479)
GO_REF:0000107		 RGD
Ensembl		 PMID:21382479 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:14707049), (PMID:8920854), (PMID:8943715) RGD PMID:8920854 PMID:8943715 PMID:14707049 NCBI chr20:48,655,549...48,661,786
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd3e CD3 epsilon subunit of T-cell receptor complex acts_upstream_of_or_within ISO (PMID:8666928) RGD PMID:8666928 NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022 		JBrowse link
G Cd5 Cd5 molecule acts_upstream_of_or_within ISO
IEA		 (PMID:10429671)
GO_REF:0000107		 RGD
Ensembl		 PMID:10429671 GO_REF:0000107 NCBI chr 1:216,790,245...216,811,209
Ensembl chr 1:207,365,337...207,386,313 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:12082630) RGD PMID:12082630 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Clec7a C-type lectin domain containing 7A involved_in ISO
IEA		 (PMID:22267217)
GO_REF:0000107		 RGD
Ensembl		 PMID:22267217 GO_REF:0000107 NCBI chr 4:164,588,737...164,599,953
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain involved_in ISO (PMID:8985253) RGD PMID:8985253 NCBI chr 7:31,827,131...31,839,796
Ensembl chr 7:29,798,586...29,952,907 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of ISO
IEA		 MGI:1858008|MGI:2148567|MGI:98957 (PMID:15131783), (PMID:20454446)
GO_REF:0000107		 RGD
Ensembl		 PMID:15131783 PMID:20454446 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dap death-associated protein involved_in IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:7828849)		 GO_Central
Ensembl
RGD		 PMID:7828849 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:83,910,113...83,962,673
Ensembl chr 2:82,199,280...82,251,752 		JBrowse link
G Dapk1 death associated protein kinase 1 involved_in ISO (PMID:7828849) RGD PMID:7828849 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dapk3 death-associated protein kinase 3 acts_upstream_of_or_within ISO
IEA		 MGI:1197015|MGI:2149961 (PMID:12917339), (PMID:9488481)
GO_REF:0000107		 RGD
Ensembl		 PMID:9488481 PMID:12917339 GO_REF:0000107 NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:8,524,183...8,532,558 		JBrowse link
G Dapl1 death associated protein-like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:64,369,734...64,389,677
Ensembl chr 3:43,960,810...43,980,940 		JBrowse link
G Daxx death-domain associated protein acts_upstream_of_or_within ISO MGI:1203520|MGI:2149961 (PMID:12917339) RGD PMID:12917339 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein involved_in ISO (PMID:10972280) RGD PMID:10972280 NCBI chr12:38,716,668...38,731,285
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dido1 death inducer-obliterator 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10393935)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:10393935 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:188,150,100...188,203,445
Ensembl chr 3:167,772,770...167,817,218 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO
IEA		 (PMID:11101870), (PMID:8565075)
GO_REF:0000107		 RGD
Ensembl		 PMID:8565075 PMID:11101870 GO_REF:0000107 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of
involved_in		 ISO
IEA
IBA		 MGI:4888719 (PMID:21209208)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21209208 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:130,633,348...130,659,168 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within IMP
ISO		 (PMID:7511063), (PMID:8666928) RGD PMID:7511063 PMID:8666928 PMID:16953119 RGD:1600313 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15629131), (PMID:7511063)
GO_REF:0000107
(PMID:11101870), (PMID:18293083)		 RGD
Ensembl		 PMID:7511063 PMID:11101870 PMID:15629131 PMID:18293083 GO_REF:0000107 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Hip1 huntingtin interacting protein 1 involved_in ISO (PMID:11007801) RGD PMID:11007801 NCBI chr12:26,769,868...26,904,367
Ensembl chr12:21,133,406...21,267,725 		JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of
involved_in		 ISO
IEA
IBA		 UniProtKB:Q8WYH8 (PMID:21750715)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21750715 GO_REF:0000033 GO_REF:0000107 NCBI chr10:55,900,610...55,912,975
Ensembl chr10:55,401,982...55,414,114 		JBrowse link
G Ing5 inhibitor of growth family, member 5 acts_upstream_of ISO
IEA		 MGI:2144284 (PMID:21750715)
GO_REF:0000107		 RGD
Ensembl		 PMID:21750715 GO_REF:0000107 NCBI chr 9:101,772,845...101,793,734
Ensembl chr 9:94,326,548...94,344,220 		JBrowse link
G Inhbb inhibin subunit beta B acts_upstream_of ISO
IEA		 MGI:98957 (PMID:20454446)
GO_REF:0000107		 RGD
Ensembl		 PMID:20454446 GO_REF:0000107 NCBI chr13:33,083,671...33,089,373
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO
IEA		 (PMID:20674765)
GO_REF:0000107		 RGD
Ensembl		 PMID:20674765 GO_REF:0000107 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of ISO MGI:104798 (PMID:16260493) RGD PMID:16260493 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of ISO MGI:1346862 (PMID:16458303) RGD PMID:16458303 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 acts_upstream_of ISO
IEA		 MGI:1346861 (PMID:16458303)
GO_REF:0000107		 RGD
Ensembl		 PMID:16458303 GO_REF:0000107 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:185,484,791...185,493,961
Ensembl chr 2:182,795,790...182,797,199 		JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:11060313) RGD PMID:11060313 NCBI chr 6:127,647,389...127,649,324
Ensembl chr 6:121,882,366...121,898,643
Ensembl chr17:121,882,366...121,898,643 		JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of ISO MGI:2682607|MGI:99702 (PMID:18436203) RGD PMID:18436203 NCBI chr19:40,889,531...40,893,699
Ensembl chr19:23,985,504...23,988,932 		JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO
IEA		 (PMID:15150278)
GO_REF:0000107		 RGD
Ensembl		 PMID:15150278 GO_REF:0000107 NCBI chr20:29,911,258...29,919,659
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in ISO (PMID:17264311) RGD PMID:17264311 NCBI chr12:39,505,438...39,523,349
Ensembl chr12:33,844,396...33,862,253 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in IDA PMID:12857854 BHF-UCL PMID:12857854 RGD:8554350 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO MGI:1197015|MGI:1203520 (PMID:12917339) RGD PMID:12917339 NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of ISO MGI:88174 (PMID:11290297) RGD PMID:11290297 NCBI chr10:83,178,926...83,191,610
Ensembl chr10:82,683,553...82,693,406 		JBrowse link
G Pde3a phosphodiesterase 3A involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31420216), (PMID:35104454)		 UniProt
Ensembl
RGD		 PMID:31420216 PMID:35104454 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:175,904,276...176,170,531
Ensembl chr 4:174,172,868...174,438,274 		JBrowse link
G Pidd1 p53-induced death domain protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:1306796|MGI:1336168|MGI:97295 (PMID:16183742)
GO_REF:0000107		 RGD
Ensembl		 PMID:16183742 GO_REF:0000107 NCBI chr 1:205,966,392...205,972,359
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta involved_in ISO
IEA		 (PMID:11551955)
GO_REF:0000107		 RGD
Ensembl		 PMID:11551955 GO_REF:0000107 NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of ISO
IEA		 MGI:109284 (PMID:15148382)
GO_REF:0000107		 RGD
Ensembl		 PMID:15148382 GO_REF:0000107 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of ISO MGI:1202717 (PMID:15148382) RGD PMID:15148382 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Ptgis prostaglandin I2 synthase involved_in ISO
IEA		 (PMID:11551955)
GO_REF:0000107		 RGD
Ensembl		 PMID:11551955 GO_REF:0000107 NCBI chr 3:176,347,589...176,383,251
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA		 (PMID:22267217)
GO_REF:0000107		 RGD
Ensembl		 PMID:22267217 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Sgpl1 sphingosine-1-phosphate lyase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:14570870)		 UniProt
Ensembl
RGD		 PMID:14570870 GO_REF:0000024 GO_REF:0000107 NCBI chr20:29,590,652...29,637,064
Ensembl chr20:29,047,796...29,094,084 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:11044396)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:11044396 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Slfn4 schlafen family member 4 involved_in ISO (PMID:31420216), (PMID:35104454) RGD PMID:31420216 PMID:35104454 NCBI chr10:68,492,135...68,515,674
Ensembl chr10:68,000,028...68,018,138
Ensembl chr10:68,000,028...68,018,138 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO
IEA		 (PMID:15107418)
GO_REF:0000107		 RGD
Ensembl		 PMID:15107418 GO_REF:0000107 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISO
IEA		 (PMID:22267217)
GO_REF:0000107		 RGD
Ensembl		 PMID:22267217 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
G Tfpt TCF3 fusion partner involved_in ISO
IBA
IEA		 (PMID:17041757)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:17041757 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:74,502,994...74,512,766
Ensembl chr 1:65,582,359...65,611,689 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:2679794 (PMID:12872135) RGD PMID:12872135 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tm2d1 TM2 domain containing 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:11278849)		 GO_Central
Ensembl
RGD		 PMID:11278849 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:118,136,299...118,177,639
Ensembl chr 5:113,020,760...113,050,933 		JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:75,871,835...75,889,069 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:15629131), (PMID:8208546) RGD PMID:8208546 PMID:15629131 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 involved_in IMP PMID:17998337 UniProt PMID:17998337 RGD:10047225 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Umod uromodulin acts_upstream_of_or_within ISO
IEA		 (PMID:28990932)
GO_REF:0000107		 RGD
Ensembl		 PMID:28990932 GO_REF:0000107 NCBI chr 1:183,247,676...183,261,665
Ensembl chr 1:173,816,339...173,830,302 		JBrowse link
G Vdr vitamin D receptor IDA RGD PMID:9579411 RGD:70308 NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of ISO
IEA		 MGI:88276|MGI:96571 (PMID:20454446)
GO_REF:0000107		 RGD
Ensembl		 PMID:20454446 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
apoptosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO (PMID:20885443) RGD PMID:20885443 NCBI chr 3:188,572,345...188,631,391
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within ISO
IEA		 (PMID:20885443)
GO_REF:0000107		 RGD
Ensembl		 PMID:20885443 GO_REF:0000107 NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:97,730,465...98,025,653 		JBrowse link
B cell receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
IEA		 (PMID:15214043)
GO_REF:0000107		 RGD
Ensembl		 PMID:15214043 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Nfkbiz NFKB inhibitor zeta involved_in ISO (PMID:23728777) RGD PMID:23728777 NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fadd Fas associated via death domain involved_in ISO
IEA		 (PMID:24025841)
GO_REF:0000107		 RGD
Ensembl		 PMID:24025841 GO_REF:0000107 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO
IEA		 MGI:2388026 (PMID:16365167)
GO_REF:0000107		 RGD
Ensembl		 PMID:16365167 GO_REF:0000107 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1b activin A receptor type 1B involved_in ISO
IEA		 (PMID:9884026)
GO_REF:0000107		 RGD
Ensembl		 PMID:9884026 GO_REF:0000107 NCBI chr 7:134,164,987...134,208,389
Ensembl chr 7:132,286,275...132,329,673 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in ISO
IBA		 (PMID:18852119)
GO_REF:0000033		 RGD
GO_Central		 PMID:18852119 GO_REF:0000033 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
IEA		 (PMID:15214043)
GO_REF:0000107		 RGD
Ensembl		 PMID:15214043 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO
IEA		 MGI:2158671 (PMID:10476969)
GO_REF:0000107		 RGD
Ensembl		 PMID:10476969 GO_REF:0000107 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp8 caspase 8 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:31748744)
MGI:104798|MGI:109324|MGI:1336166 (PMID:10588860), (PMID:12065591), (PMID:22089168), (PMID:22675671)
(PMID:21785459), (PMID:35446120)		 UniProt
Ensembl
RGD		 PMID:10588860 PMID:12065591 PMID:21785459 PMID:22089168 PMID:22675671 More... GO_REF:0000024 GO_REF:0000107 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cd27 CD27 molecule involved_in ISO (PMID:9177220) RGD PMID:9177220 NCBI chr 4:159,716,932...159,721,823
Ensembl chr 4:158,030,703...158,035,592 		JBrowse link
G Cd70 Cd70 molecule involved_in ISO
IEA		 (PMID:9177220)
GO_REF:0000107		 RGD
Ensembl		 PMID:9177220 GO_REF:0000107 NCBI chr 9:2,093,540...2,096,692
Ensembl chr 9:2,006,563...2,009,715 		JBrowse link
G Cttn cortactin acts_upstream_of ISO
IEA		 MGI:1924375 (PMID:22660580)
GO_REF:0000107		 RGD
Ensembl		 PMID:22660580 GO_REF:0000107 NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of ISO (PMID:15734730) RGD PMID:15734730 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Fadd Fas associated via death domain involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:16611992), (PMID:21785459)
GO_REF:0000107
MGI:1889507 (PMID:10588860), (PMID:16183742)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:10588860 PMID:16183742 PMID:16611992 PMID:21785459 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor involved_in
acts_upstream_of_or_within		 IMP
ISO		 (PMID:12011074), (PMID:17980593)
(PMID:22891283)		 RGD PMID:12011074 PMID:17980593 PMID:22891283 PMID:15519734 RGD:8662904 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand involved_in ISO
IEA		 (PMID:22891283)
GO_REF:0000107		 RGD
Ensembl		 PMID:22891283 GO_REF:0000107 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G G0s2 G0/G1switch 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19706769)		 UniProt
RGD		 PMID:19706769 GO_REF:0000024 NCBI chr13:107,335,036...107,335,948
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO UniProtKB:Q9WV60 (PMID:20371704) RGD PMID:20371704 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO UniProtKB:Q2NL51 (PMID:20371704) RGD PMID:20371704 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in ISO
IEA		 (PMID:15701637)
GO_REF:0000107		 RGD
Ensembl		 PMID:15701637 GO_REF:0000107 NCBI chr 2:193,937,261...193,988,247
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 involved_in ISO (PMID:24970806) RGD PMID:24970806 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifng interferon gamma involved_in ISO (PMID:16942485) RGD PMID:16942485 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA		 (PMID:16942485)
GO_REF:0000107		 RGD
Ensembl		 PMID:16942485 GO_REF:0000107 NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il33 interleukin 33 acts_upstream_of_or_within ISO MGI:99695 (PMID:22660580) RGD PMID:22660580 NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il4 interleukin 4 acts_upstream_of ISO (PMID:10429671) RGD PMID:10429671 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il7 interleukin 7 acts_upstream_of ISO (PMID:10429671) RGD PMID:10429671 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
IEA		 (PMID:9884026)
GO_REF:0000107		 RGD
Ensembl		 PMID:9884026 GO_REF:0000107 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO
IEA		 (PMID:12426001)
GO_REF:0000107		 RGD
Ensembl		 PMID:12426001 GO_REF:0000107 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Krt18 keratin 18 acts_upstream_of_or_within ISO MGI:2178045 (PMID:10747083) RGD PMID:10747083 NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:133,157,475...133,161,166
Ensembl chr10:133,157,475...133,161,166 		JBrowse link
G Krt8 keratin 8 acts_upstream_of_or_within ISO MGI:2178042 (PMID:10747083) RGD PMID:10747083 NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:14522843 RGD:2304239 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18852119)		 UniProt
Ensembl
RGD		 PMID:18852119 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,484,791...185,493,961
Ensembl chr 2:182,795,790...182,797,199 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 acts_upstream_of_or_within ISO (PMID:10924506) RGD PMID:10924506 NCBI chr16:19,560,526...19,567,500
Ensembl chr16:19,526,565...19,535,726
Ensembl chr 7:19,526,565...19,535,726 		JBrowse link
G Ngfr nerve growth factor receptor involved_in ISO
IEA		 (PMID:26268439)
GO_REF:0000107		 RGD
Ensembl		 PMID:26268439 GO_REF:0000107 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:8614837
MGI:2386080 (PMID:17286969)
PMID:12857854		 RGD PMID:17286969 PMID:8614837 PMID:12857854 RGD:69918, RGD:8554350 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 acts_upstream_of_or_within ISO (PMID:12065591) RGD PMID:12065591 NCBI chr15:26,494,722...26,517,893
Ensembl chr15:24,034,106...24,044,338 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 acts_upstream_of ISO
IEA		 (PMID:15858817)
GO_REF:0000107		 RGD
Ensembl		 PMID:15858817 GO_REF:0000107 NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 involved_in ISO
IEA		 (PMID:16207722)
GO_REF:0000107		 RGD
Ensembl		 PMID:16207722 GO_REF:0000107 NCBI chr10:13,610,000...13,687,226
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
G Pidd1 p53-induced death domain protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:1261423 (PMID:16183742)
GO_REF:0000107		 RGD
Ensembl		 PMID:16183742 GO_REF:0000107 NCBI chr 1:205,966,392...205,972,359
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO
IEA		 MGI:2429949 (PMID:9806545)
GO_REF:0000107		 RGD
Ensembl		 PMID:9806545 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of ISO MGI:2668456 (PMID:15259009) RGD PMID:15259009 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of ISO
IEA		 MGI:3690329 (PMID:17015619)
GO_REF:0000107		 RGD
Ensembl		 PMID:17015619 GO_REF:0000107 NCBI chr 5:17,948,522...18,012,434
Ensembl chr 5:13,161,648...13,225,560 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:10521396), (PMID:7538908), (PMID:8612133)
GO_REF:0000107		 RGD
Ensembl		 PMID:7538908 PMID:8612133 PMID:10521396 GO_REF:0000107 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Rnf41 ring finger protein 41 involved_in ISO
IEA		 (PMID:14765125)
GO_REF:0000107		 RGD
Ensembl		 PMID:14765125 GO_REF:0000107 NCBI chr 7:1,422,651...1,461,700
Ensembl chr 7:838,203...865,511 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of ISO
IEA		 MGI:3045799 (PMID:14976225)
GO_REF:0000107		 RGD
Ensembl		 PMID:14976225 GO_REF:0000107 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 acts_upstream_of_or_within ISO
IEA		 (PMID:12235122)
GO_REF:0000107		 RGD
Ensembl		 PMID:12235122 GO_REF:0000107 NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:94,425,339...94,446,534 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO
IEA
IBA		 (PMID:9177220)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:9177220 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:137,526,416...137,530,790
Ensembl chr 6:131,705,323...131,709,690 		JBrowse link
G Smad3 SMAD family member 3 involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:15334054)		 Ensembl
RGD		 PMID:15334054 PMID:11839804 GO_REF:0000107, RGD:2301029 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
RNAcentral:URS0000554A4F_9606 (PMID:22821565)		 Ensembl
RGD		 PMID:22821565 GO_REF:0000107 NCBI chr18:69,518,988...69,549,684
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15334054), (PMID:26572508)		 UniProt
Ensembl
RGD		 PMID:15334054 PMID:26572508 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17217916)		 AgBase
Ensembl
RGD		 PMID:17217916 GO_REF:0000024 GO_REF:0000107 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tlr3 toll-like receptor 3 involved_in ISO
IEA		 (PMID:21737330)
GO_REF:0000107		 RGD
Ensembl		 PMID:21737330 GO_REF:0000107 NCBI chr16:53,554,916...53,572,321
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11577081), (PMID:16611992)
GO_REF:0000107
MGI:104798|MGI:108212|MGI:1261423 (PMID:19498109), (PMID:22089168)		 RGD
Ensembl		 PMID:11577081 PMID:16611992 PMID:19498109 PMID:22089168 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b involved_in ISO (PMID:21785459) RGD PMID:21785459 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A acts_upstream_of_or_within ISO (PMID:12821115) RGD PMID:12821115 NCBI chr10:13,211,670...13,213,666
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857262 (PMID:7990930)		 GO_Central
RGD		 PMID:7990930 GO_REF:0000033 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfsf12 TNF superfamily member 12 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12821115)		 GO_Central
RGD		 PMID:12821115 GO_REF:0000033 NCBI chr10:54,902,616...54,912,628
Ensembl chr10:54,403,870...54,413,213 		JBrowse link
G Tradd TNFRSF1A-associated via death domain involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:16611992)
MGI:104798|MGI:108212 (PMID:22089168)
GO_REF:0000033		 RGD
GO_Central		 PMID:16611992 PMID:22089168 GO_REF:0000033 NCBI chr19:50,046,057...50,048,158
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (PMID:19366691) RGD PMID:19366691 NCBI chr19:59,338,402...60,269,323
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of ISO
IEA		 MGI:95484 (PMID:17980593)
GO_REF:0000107		 RGD
Ensembl		 PMID:17980593 GO_REF:0000107 NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
G Zfp110 zinc finger protein 110 acts_upstream_of_or_within ISO MGI:2156881 (PMID:10545116) RGD PMID:10545116 NCBI chr 1:82,509,563...82,533,294
Ensembl chr 1:73,445,336...73,461,086 		JBrowse link
extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within ISO MGI:1890081 (PMID:12115603), (PMID:12431371), (PMID:12944463), (PMID:14967141) RGD PMID:12115603 PMID:12431371 PMID:12944463 PMID:14967141 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bag3 BAG cochaperone 3 acts_upstream_of_or_within ISO
IEA		 (PMID:11527400)
GO_REF:0000107		 RGD
Ensembl		 PMID:11527400 GO_REF:0000107 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:1197519|MGI:99702 (PMID:15680329), (PMID:15967824)		 GO_Central
Ensembl
RGD		 PMID:15680329 PMID:15967824 GO_REF:0000033 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:1097161|MGI:1197519 (PMID:15680329), (PMID:15967824)		 GO_Central
Ensembl
RGD		 PMID:15680329 PMID:15967824 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1309517 (PMID:12082633)		 GO_Central
RGD		 PMID:12082633 GO_REF:0000033 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12115603)		 GO_Central
RGD		 PMID:12115603 GO_REF:0000033 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l10 Bcl2-like 10 involved_in
acts_upstream_of		 IBA
ISO		 GO_REF:0000033
(PMID:9878060)		 GO_Central
RGD		 PMID:9878060 GO_REF:0000033 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Bcl2l11 Bcl2-like 11 acts_upstream_of_or_within ISO MGI:1097161|MGI:2156498|MGI:99702 (PMID:15967824) RGD PMID:15967824 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl2l2 Bcl2-like 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12115603)		 GO_Central
RGD		 PMID:12115603 GO_REF:0000033 NCBI chr15:32,326,686...32,337,834
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Casp2 caspase 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:2159368 (PMID:11536012)		 GO_Central
Ensembl
RGD		 PMID:11536012 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of ISO
IEA		 MGI:2152978 (PMID:9299161)
GO_REF:0000107		 RGD
Ensembl		 PMID:9299161 GO_REF:0000107 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of ISO
IEA		 MGI:2677796 (PMID:22411810)
GO_REF:0000107		 RGD
Ensembl		 PMID:22411810 GO_REF:0000107 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of ISO
IEA		 (PMID:18322241), (PMID:18971423)
GO_REF:0000107		 RGD
Ensembl		 PMID:18322241 PMID:18971423 GO_REF:0000107 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 involved_in ISO (PMID:17701904) RGD PMID:17701904 NCBI chr 7:1,579,079...1,600,379
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 acts_upstream_of ISO MGI:1857803 (PMID:15817220) RGD PMID:15817220 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within ISO
IEA		 (PMID:11700312)
GO_REF:0000107		 RGD
Ensembl		 PMID:11700312 GO_REF:0000107 NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Fadd Fas associated via death domain acts_upstream_of_or_within ISO
IEA		 (PMID:13679421)
GO_REF:0000107		 RGD
Ensembl		 PMID:13679421 GO_REF:0000107 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO MGI:1856334|MGI:1861923 (PMID:13679421) RGD PMID:13679421 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of ISO
IEA		 MGI:1859647 (PMID:16956603)
GO_REF:0000107		 RGD
Ensembl		 PMID:16956603 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Foxo3 forkhead box O3 acts_upstream_of_or_within ISO
IEA		 MGI:1096330 (PMID:12431371)
GO_REF:0000107		 RGD
Ensembl		 PMID:12431371 GO_REF:0000107 NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Igf1 insulin-like growth factor 1 acts_upstream_of_or_within ISO (PMID:12431371) RGD PMID:12431371 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il1a interleukin 1 alpha acts_upstream_of_or_within ISO MGI:2157371 (PMID:11536012) RGD PMID:11536012 NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within ISO
IEA		 MGI:2157396 (PMID:11536012)
GO_REF:0000107		 RGD
Ensembl		 PMID:11536012 GO_REF:0000107 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:12082633) RGD PMID:12082633 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:11527400), (PMID:12124386), (PMID:12944463), (PMID:14967141), (PMID:15231831), (PMID:15680329) RGD PMID:11527400 PMID:12124386 PMID:12944463 PMID:14967141 PMID:15231831 More... NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12115603) RGD PMID:12115603 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO
IEA		 (PMID:15591537)
GO_REF:0000107		 RGD
Ensembl		 PMID:15591537 GO_REF:0000107 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Kitlg KIT ligand acts_upstream_of_or_within ISO
IEA		 (PMID:15039234)
GO_REF:0000107		 RGD
Ensembl		 PMID:15039234 GO_REF:0000107 NCBI chr 7:36,782,621...36,863,796
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Lcn2 lipocalin 2 acts_upstream_of_or_within ISO
IEA		 (PMID:16377569)
GO_REF:0000107		 RGD
Ensembl		 PMID:16377569 GO_REF:0000107 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:16543145)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:16543145 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mknk1 MAPK interacting serine/threonine kinase 1 acts_upstream_of_or_within ISO MGI:3052673|MGI:894279 (PMID:17903173) RGD PMID:17903173 NCBI chr 5:134,554,881...134,594,392
Ensembl chr 5:129,318,170...129,357,639 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 acts_upstream_of_or_within ISO
IEA		 MGI:3052675|MGI:894316 (PMID:17903173)
GO_REF:0000107		 RGD
Ensembl		 PMID:17903173 GO_REF:0000107 NCBI chr 7:9,690,385...9,701,527
Ensembl chr 7:9,039,728...9,050,827 		JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:127,647,389...127,649,324
Ensembl chr 6:121,882,366...121,898,643
Ensembl chr17:121,882,366...121,898,643 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of ISO
IEA		 MGI:1857478 (PMID:15039234)
GO_REF:0000107		 RGD
Ensembl		 PMID:15039234 GO_REF:0000107 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Ngf nerve growth factor acts_upstream_of_or_within ISO (PMID:14623868) RGD PMID:14623868 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of ISO
IEA		 (PMID:8206089)
GO_REF:0000107		 RGD
Ensembl		 PMID:8206089 GO_REF:0000107 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within ISO MGI:3029528 (PMID:12431371) RGD PMID:12431371 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bag3 BAG cochaperone 3 acts_upstream_of_or_within ISO
IEA		 (PMID:10597216)
GO_REF:0000107		 RGD
Ensembl		 PMID:10597216 GO_REF:0000107 NCBI chr 1:192,533,460...192,557,281
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO
IEA		 (PMID:10597216)
GO_REF:0000107		 RGD
Ensembl		 PMID:10597216 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO (PMID:10597216) RGD PMID:10597216 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bex3 brain expressed X-linked 3 acts_upstream_of_or_within ISO
IEA		 PR:Q9Z0W1 (PMID:10764727)
GO_REF:0000107		 RGD
Ensembl		 PMID:10764727 GO_REF:0000107 NCBI chr  X:104,064,896...104,066,425
Ensembl chr  X:99,273,161...99,274,800 		JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 involved_in ISO
IEA
ISS		 (PMID:18188704)
GO_REF:0000107		 RGD
Ensembl		 PMID:18188704 PMID:18188704 GO_REF:0000107, RGD:8553738 NCBI chr 1:252,973,818...252,980,873
Ensembl chr 1:243,024,614...243,031,653 		JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 MGI:2177602|MGI:3054930 (PMID:15322156)
GO_REF:0000107
GO_REF:0000033
(PMID:9184224)		 RGD
Ensembl
GO_Central		 PMID:9184224 PMID:15322156 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp8ap2 caspase 8 associated protein 2 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:17245429)
GO_REF:0000107
(PMID:10235259)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:10235259 PMID:17245429 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:51,809,366...51,848,633
Ensembl chr 5:47,014,667...47,052,275 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA		 (PMID:19903888)
GO_REF:0000107		 RGD
Ensembl		 PMID:19903888 GO_REF:0000107 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Dapk1 death associated protein kinase 1 acts_upstream_of_or_within ISO
IEA		 MGI:3042776|MGI:3052030 (PMID:15010850), (PMID:20053891)
GO_REF:0000107		 RGD
Ensembl		 PMID:15010850 PMID:20053891 GO_REF:0000107 NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Daxx death-domain associated protein involved_in ISO
IEA		 (PMID:9215629)
GO_REF:0000107		 RGD
Ensembl		 PMID:9215629 GO_REF:0000107 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:18846110) RGD PMID:18846110 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Ddx47 DEAD-box helicase 47 involved_in ISO
IEA		 (PMID:15977068)
GO_REF:0000107		 RGD
Ensembl		 PMID:15977068 GO_REF:0000107 NCBI chr 4:169,577,013...169,589,473
Ensembl chr 4:167,845,640...167,859,115 		JBrowse link
G Dedd death effector domain-containing involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:9774341)		 GO_Central
Ensembl
RGD		 PMID:9774341 GO_REF:0000033 GO_REF:0000107 NCBI chr13:86,286,341...86,301,789
Ensembl chr13:83,756,108...83,769,332 		JBrowse link
G Dedd2 death effector domain containing 2 involved_in ISO
IEA
IBA		 (PMID:11741985)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:11741985 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:89,916,906...89,934,663
Ensembl chr 1:80,792,000...80,807,714 		JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 involved_in ISO
IEA
IBA
ISS		 (PMID:20563667)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:20563667 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr18:30,325,369...30,349,285
Ensembl chr18:30,085,126...30,098,756 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO
IEA		 (PMID:24025841), (PMID:9184224)
GO_REF:0000107		 RGD
Ensembl		 PMID:9184224 PMID:24025841 GO_REF:0000107 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within
involved_in		 ISO MGI:1096330|MGI:1856334 (PMID:10429671), (PMID:10588860), (PMID:12431371), (PMID:12801066), (PMID:15039234), (PMID:15632112), (PMID:18363966), (PMID:8524870)
(PMID:12221075), (PMID:9333124)
(PMID:10950869)		 RGD PMID:8524870 PMID:9333124 PMID:10429671 PMID:10588860 PMID:10950869 More... NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand acts_upstream_of_or_within
involved_in		 IMP
IEA
ISO
IBA		 GO_REF:0000107
(PMID:10588860), (PMID:15039234)
GO_REF:0000033
(PMID:26582200)
(PMID:18835034)		 Ensembl
RGD
GO_Central		 PMID:10588860 PMID:15039234 PMID:18835034 PMID:26582200 PMID:16689665 GO_REF:0000033 GO_REF:0000107, RGD:1582444 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Gabarap GABA type A receptor-associated protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:15977068)		 UniProt
RGD		 PMID:15977068 GO_REF:0000024 NCBI chr10:55,213,465...55,216,787
Ensembl chr10:54,714,198...54,717,765 		JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of ISO MGI:2387671 (PMID:19139395) RGD PMID:19139395 NCBI chr16:37,721,374...37,723,950
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140 		JBrowse link
G Il18 interleukin 18 involved_in ISO (PMID:11131641)
(PMID:11429161)		 RGD PMID:11131641 PMID:11429161 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of ISO MGI:1916885 (PMID:20053891) RGD PMID:20053891 NCBI chr 1:256,704,087...256,727,661
Ensembl chr 1:246,762,472...246,786,408 		JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:127,647,389...127,649,324
Ensembl chr 6:121,882,366...121,898,643
Ensembl chr17:121,882,366...121,898,643 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857478|MGI:97583 (PMID:15039234)
GO_REF:0000107		 RGD
Ensembl		 PMID:15039234 GO_REF:0000107 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Ngf nerve growth factor involved_in ISO
IEA		 (PMID:14985763)
GO_REF:0000107		 RGD
Ensembl		 PMID:14985763 GO_REF:0000107 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Pidd1 p53-induced death domain protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:109324 (PMID:16183742)
GO_REF:0000107		 RGD
Ensembl		 PMID:16183742 GO_REF:0000107 NCBI chr 1:205,966,392...205,972,359
Ensembl chr 1:196,536,834...196,542,699 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 acts_upstream_of_or_within ISO MGI:97306 (PMID:15039234) RGD PMID:15039234 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of ISO
IEA		 MGI:2388026|MGI:95484|MGI:99255 (PMID:16365167)
GO_REF:0000107		 RGD
Ensembl		 PMID:16365167 GO_REF:0000107 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 acts_upstream_of_or_within ISO MGI:95484|MGI:97847 (PMID:16365167) RGD PMID:16365167 NCBI chr 6:45,407,823...45,502,773
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of ISO
IEA		 MGI:2387096 (PMID:10811619)
GO_REF:0000107		 RGD
Ensembl		 PMID:10811619 GO_REF:0000107 NCBI chr 2:114,175,534...114,203,663
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Sort1 sortilin 1 involved_in ISO
IEA		 (PMID:14985763)
GO_REF:0000107		 RGD
Ensembl		 PMID:14985763 GO_REF:0000107 NCBI chr 2:198,609,466...198,690,481
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Stk3 serine/threonine kinase 3 acts_upstream_of ISO MGI:104798|MGI:1928487|MGI:1929004 (PMID:20080598) RGD PMID:20080598 NCBI chr 7:67,938,341...68,208,472
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of ISO
IEA		 MGI:104798|MGI:1928487 (PMID:20080598)
GO_REF:0000107		 RGD
Ensembl		 PMID:20080598 GO_REF:0000107 NCBI chr 3:173,165,238...173,247,135
Ensembl chr 3:152,745,681...152,827,744 		JBrowse link
G Tnf tumor necrosis factor involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:10521396), (PMID:18202225), (PMID:18676776)
GO_REF:0000107
MGI:1096330|MGI:1928487|MGI:1929004 (PMID:12431371), (PMID:20080598)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:10521396 PMID:12431371 PMID:18202225 PMID:18676776 PMID:20080598 GO_REF:0000033 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b IMP RGD PMID:19934367 RGD:4142856 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
fibroblast growth factor receptor apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO
IEA		 MGI:1859647 (PMID:16720875)
GO_REF:0000107		 RGD
Ensembl		 PMID:16720875 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:2153811 (PMID:16720875) RGD PMID:16720875 NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO
IEA		 (PMID:17561467)
GO_REF:0000107		 RGD
Ensembl		 PMID:17561467 GO_REF:0000107 NCBI chr14:81,211,800...81,227,215
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
granzyme-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ube4b ubiquitination factor E4B involved_in ISO
IEA		 (PMID:11802788)
GO_REF:0000107		 RGD
Ensembl		 PMID:11802788 GO_REF:0000107 NCBI chr 5:165,049,897...165,153,572
Ensembl chr 5:159,766,829...159,870,509 		JBrowse link
hormone-mediated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone IDA RGD PMID:11790788 RGD:1358682 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Esr2 estrogen receptor 2 acts_upstream_of_or_within ISO MGI:2152217 (PMID:15187231) RGD PMID:15187231 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Mettl21c methyltransferase 21C, AARS1 lysine acts_upstream_of_or_within ISO
IEA		 (PMID:24677265)
GO_REF:0000107		 RGD
Ensembl		 PMID:24677265 GO_REF:0000107 NCBI chr 9:53,625,473...53,637,220
Ensembl chr 9:46,134,001...46,145,112 		JBrowse link
intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:18676776)		 UniProt
GO_Central
RGD		 PMID:18676776 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO
IEA		 (PMID:22006182)
GO_REF:0000107		 RGD
Ensembl		 PMID:22006182 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
MGI:2158306 (PMID:14502238)
(PMID:16462759), (PMID:9219694)		 UniProt
Ensembl
RGD		 PMID:9219694 PMID:14502238 PMID:16462759 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO
IEA		 (PMID:17024184)
GO_REF:0000002		 RGD
InterPro		 PMID:17024184 GO_REF:0000002 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Bnip3 BCL2 interacting protein 3 acts_upstream_of_or_within ISO
IEA		 MGI:96224 (PMID:16954213)
GO_REF:0000107		 RGD
Ensembl		 PMID:16954213 GO_REF:0000107 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of ISO MGI:3793294 (PMID:17938250) RGD PMID:17938250 NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G Casp12 caspase 12 involved_in IMP PMID:10638761 RGD
ParkinsonsUK-UCL		 PMID:17083921 PMID:10638761 RGD:2311464, RGD:10047306 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 involved_in ISO
IEA		 (PMID:15565177)
GO_REF:0000107		 RGD
Ensembl		 PMID:15565177 GO_REF:0000107 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:15123740) RGD PMID:15123740 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp9 caspase 9 involved_in ISO
IEA		 (PMID:35446120)
GO_REF:0000107		 RGD
Ensembl		 PMID:35446120 GO_REF:0000107 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Casp9_v1 caspase-9-carboxyl-terminal divergent involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Clu clusterin involved_in ISO
ISS		 (PMID:21567405)
GO_REF:0000024		 RGD
UniProt		 PMID:21567405 GO_REF:0000024 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Coa8 cytochrome c oxidase assembly factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000002
(PMID:16782708)		 InterPro
RGD		 PMID:16782708 GO_REF:0000002 NCBI chr 6:136,593,399...136,618,237
Ensembl chr 6:130,771,199...130,797,081 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:16301996) RGD PMID:16301996 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Flcn folliculin acts_upstream_of ISO
IEA		 MGI:4348628 (PMID:21258407)
GO_REF:0000107		 RGD
Ensembl		 PMID:21258407 GO_REF:0000107 NCBI chr10:45,088,164...45,107,581
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO
IEA		 UniProtKB:O08734 (PMID:19255499)
GO_REF:0000107		 RGD
Ensembl		 PMID:19255499 GO_REF:0000107 NCBI chr12:38,251,085...38,279,756
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Hras HRas proto-oncogene, GTPase acts_upstream_of_or_within ISO MGI:109326 (PMID:16954213) RGD PMID:16954213 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Htra2 HtrA serine peptidase 2 acts_upstream_of_or_within ISO
IEA		 MGI:3512633 (PMID:15509788)
GO_REF:0000107		 RGD
Ensembl		 PMID:15509788 GO_REF:0000107 NCBI chr 4:117,114,631...117,117,793
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:128,355,312...128,361,783
Ensembl chr 6:122,590,472...122,779,294 		JBrowse link
G Ifi27l2a interferon, alpha-inducible protein 27 like 2A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:128,363,658...128,365,144
Ensembl chr 6:122,598,872...122,600,360 		JBrowse link
G Ivns1abp influenza virus NS1A binding protein acts_upstream_of ISO
IEA		 MGI:4820513 (PMID:15485691)
GO_REF:0000107		 RGD
Ensembl		 PMID:15485691 GO_REF:0000107 NCBI chr13:65,977,069...65,996,685
Ensembl chr13:63,427,041...63,446,701 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:28464033) RGD PMID:28464033 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lgals12 galectin 12 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:11435439)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:11435439 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:214,261,216...214,272,825
Ensembl chr 1:204,832,065...204,842,759 		JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in ISO
IEA
ISS		 (PMID:18852119)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:18852119 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,484,791...185,493,961
Ensembl chr 2:182,795,790...182,797,199 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO
IEA		 MGI:2151803 (PMID:14632208)
GO_REF:0000107		 RGD
Ensembl		 PMID:14632208 GO_REF:0000107 NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Nbn nibrin acts_upstream_of_or_within ISO
IEA		 MGI:3027036 (PMID:18614044)
GO_REF:0000107		 RGD
Ensembl		 PMID:18614044 GO_REF:0000107 NCBI chr 5:34,256,678...34,291,163
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Nlrp1a NLR family, pyrin domain containing 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:56,277,134...56,332,229
Ensembl chr10:55,778,560...55,825,180 		JBrowse link
G Nlrp1b NLR family, pyrin domain containing 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:56,336,957...56,412,796
Ensembl chr10:55,843,001...55,912,774 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO (PMID:24312627) RGD PMID:24312627 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Plscr1 phospholipid scramblase 1 involved_in ISO
IEA		 (PMID:15863367)
GO_REF:0000107		 RGD
Ensembl		 PMID:15863367 GO_REF:0000107 NCBI chr 8:101,662,512...101,684,474
Ensembl chr 8:92,784,356...92,804,692 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14500711) RGD PMID:14500711 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Prkca protein kinase C, alpha acts_upstream_of_or_within ISO MGI:3029711 (PMID:12928424) RGD PMID:12928424 NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Pycard PYD and CARD domain containing involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Sgpp1 sphingosine-1-phosphate phosphatase 1 acts_upstream_of_or_within ISO
IEA		 (PMID:10859351)
GO_REF:0000107		 RGD
Ensembl		 PMID:10859351 GO_REF:0000107 NCBI chr 6:100,161,024...100,182,214
Ensembl chr 6:94,425,339...94,446,534 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (PMID:23313858) RGD PMID:23313858 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor NOT|involved_in ISO (PMID:12011449) RGD PMID:12011449 NCBI chr 6:137,526,416...137,530,790
Ensembl chr 6:131,705,323...131,709,690 		JBrowse link
intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO
IEA		 (PMID:10479688)
GO_REF:0000107		 RGD
Ensembl		 PMID:10479688 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO
IEA		 (PMID:15102863)
GO_REF:0000107		 RGD
Ensembl		 PMID:15102863 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Casp6 caspase 6 involved_in ISO
IEA
ISS		 (PMID:22858542)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22858542 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:221,140,287...221,152,727
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of ISO MGI:98834 (PMID:26158450) RGD PMID:26158450 NCBI chr 8:112,041,586...112,093,061
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Ddx5 DEAD-box helicase 5 involved_in ISO
IEA		 (PMID:15660129)
GO_REF:0000107		 RGD
Ensembl		 PMID:15660129 GO_REF:0000107 NCBI chr10:92,224,393...92,231,928
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G E2f1 E2F transcription factor 1 acts_upstream_of_or_within ISO
IEA		 (PMID:11095619)
GO_REF:0000107		 RGD
Ensembl		 PMID:11095619 GO_REF:0000107 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G E2f2 E2F transcription factor 2 acts_upstream_of_or_within ISO
IEA		 (PMID:11095619)
GO_REF:0000107		 RGD
Ensembl		 PMID:11095619 GO_REF:0000107 NCBI chr 5:153,682,789...153,706,087
Ensembl chr 5:148,399,642...148,421,217 		JBrowse link
G Eda2r ectodysplasin A2 receptor acts_upstream_of_or_within ISO
IEA		 MGI:98834 (PMID:20434500)
GO_REF:0000107		 RGD
Ensembl		 PMID:20434500 GO_REF:0000107 NCBI chr  X:66,225,557...66,280,674
Ensembl chr  X:62,228,229...62,269,268 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit acts_upstream_of_or_within ISO
IEA		 MGI:2183949 (PMID:18545656)
GO_REF:0000107		 RGD
Ensembl		 PMID:18545656 GO_REF:0000107 NCBI chr 1:88,161,342...88,175,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:15313915)		 UniProt
GO_Central
Ensembl
RGD		 PMID:15313915 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr15:16,365,401...17,872,901
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 involved_in ISO
ISS		 (PMID:16835243)
GO_REF:0000024		 RGD
UniProt		 PMID:16835243 GO_REF:0000024 NCBI chr10:39,490,225...39,493,970
Ensembl chr 4:92,100,973...92,101,568 		JBrowse link
G Jmy junction mediating and regulatory protein, p53 cofactor involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:10518217)		 GO_Central
RGD		 PMID:10518217 GO_REF:0000033 NCBI chr 2:26,401,047...26,465,959
Ensembl chr 2:24,668,854...24,731,006 		JBrowse link
G Mybbp1a MYB binding protein 1a involved_in ISO
IEA		 (PMID:21471221)
GO_REF:0000107		 RGD
Ensembl		 PMID:21471221 GO_REF:0000107 NCBI chr10:57,555,458...57,565,819
Ensembl chr10:57,056,874...57,067,255 		JBrowse link
G Pdk2 pyruvate dehydrogenase kinase 2 involved_in ISO
IEA		 (PMID:22123926)
GO_REF:0000107		 RGD
Ensembl		 PMID:22123926 GO_REF:0000107 NCBI chr10:80,469,388...80,483,988
Ensembl chr10:79,972,556...79,987,085 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 acts_upstream_of_or_within ISO
IEA		 (PMID:10733530)
GO_REF:0000107		 RGD
Ensembl		 PMID:10733530 GO_REF:0000107 NCBI chr 1:15,361,784...15,374,230
Ensembl chr 1:13,542,067...13,554,511 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15102863)
(PMID:14500851)		 RGD PMID:14500851 PMID:15102863 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO
IEA		 (PMID:14992722)
GO_REF:0000107		 RGD
Ensembl		 PMID:14992722 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17145718)		 UniProt
RGD		 PMID:17145718 GO_REF:0000024 NCBI chr15:87,668,328...87,674,643
Ensembl chr15:81,257,781...81,259,728 		JBrowse link
G Pou4f2 POU class 4 homeobox 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17145718)		 UniProt
RGD		 PMID:17145718 GO_REF:0000024 NCBI chr19:46,390,958...46,394,599
Ensembl chr19:29,486,686...29,490,327 		JBrowse link
G Ppp1r13b protein phosphatase 1, regulatory subunit 13B involved_in ISO (PMID:11684014) RGD PMID:11684014 NCBI chr 6:136,711,834...136,785,068
Ensembl chr 6:130,890,679...130,963,330 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA		 (PMID:14730312)
GO_REF:0000107		 RGD
Ensembl		 PMID:14730312 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of ISO
IEA		 MGI:3584037 (PMID:15989966)
GO_REF:0000107		 RGD
Ensembl		 PMID:15989966 GO_REF:0000107 NCBI chr10:2,637,016...2,672,338
Ensembl chr10:2,129,978...2,165,663 		JBrowse link
G Rrp8 ribosomal RNA processing 8 involved_in ISO
IEA		 (PMID:21471221)
GO_REF:0000107		 RGD
Ensembl		 PMID:21471221 GO_REF:0000107 NCBI chr 1:169,489,829...169,500,551
Ensembl chr 1:160,084,295...160,089,331 		JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within ISO
IEA		 (PMID:12135983)
GO_REF:0000107		 RGD
Ensembl		 PMID:12135983 GO_REF:0000107 NCBI chr 8:118,569,975...118,584,880
Ensembl chr 8:109,691,522...109,706,408 		JBrowse link
G Stk11 serine/threonine kinase 11 involved_in ISO
ISS		 (PMID:11430832)
GO_REF:0000024		 RGD
UniProt		 PMID:11430832 GO_REF:0000024 NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:12172011), (PMID:16322561), (PMID:17310983)
GO_REF:0000107
MGI:2442860 (PMID:12135983), (PMID:16107883), (PMID:20434500)		 RGD
Ensembl		 PMID:12135983 PMID:12172011 PMID:16107883 PMID:16322561 PMID:17310983 More... GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53bp2 tumor protein p53 binding protein, 2 involved_in ISO
IEA		 (PMID:11684014)
GO_REF:0000107		 RGD
Ensembl		 PMID:11684014 GO_REF:0000107 NCBI chr13:96,620,429...96,677,090
Ensembl chr13:94,088,709...94,145,432 		JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO MGI:98834 (PMID:11058590) RGD PMID:11058590 NCBI chr19:59,338,402...60,269,323
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
G Zfp385b zinc finger protein 385B involved_in ISO (PMID:22945289) RGD PMID:22945289 NCBI chr 3:82,762,387...83,140,856
Ensembl chr 3:62,355,196...62,640,510 		JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO
IEA		 MGI:1328356|MGI:88138 (PMID:15983387)
GO_REF:0000107		 RGD
Ensembl		 PMID:15983387 GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Atm ATM serine/threonine kinase acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:109337|MGI:1933746 (PMID:11040211), (PMID:16777961), (PMID:17476307)
GO_REF:0000033		 RGD
GO_Central		 PMID:11040211 PMID:16777961 PMID:17476307 GO_REF:0000033 NCBI chr 8:62,724,939...62,829,040
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within ISO MGI:3029528 (PMID:12431371), (PMID:15231831) RGD PMID:12431371 PMID:15231831 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 MGI:1197519|MGI:99702 (PMID:15901672), (PMID:15967824)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:15901672 PMID:15967824 GO_REF:0000033 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA
ISS		 MGI:1097161|MGI:1197519|MGI:1857429 (PMID:12952892), (PMID:15901672), (PMID:15967824)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024
(PMID:11912183)		 RGD
Ensembl
GO_Central
UniProt		 PMID:11912183 PMID:12952892 PMID:15901672 PMID:15967824 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2442925 (PMID:15983387)
GO_REF:0000033		 RGD
GO_Central		 PMID:15983387 GO_REF:0000033 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:2158303 (PMID:14517295)
GO_REF:0000033		 RGD
GO_Central		 PMID:14517295 GO_REF:0000033 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l10 Bcl2-like 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Bcl2l11 Bcl2-like 11 acts_upstream_of_or_within ISO (PMID:11546872)
MGI:1097161|MGI:99702 (PMID:15967824)		 RGD PMID:11546872 PMID:15967824 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl2l2 Bcl2-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:32,326,686...32,337,834
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Brca1 BRCA1, DNA repair associated acts_upstream_of_or_within ISO (PMID:14654789) RGD PMID:14654789 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brca2 BRCA2, DNA repair associated acts_upstream_of_or_within ISO
IEA		 MGI:107202 (PMID:17476307)
GO_REF:0000107		 RGD
Ensembl		 PMID:17476307 GO_REF:0000107 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:59,819...100,567 		JBrowse link
G Casp2 caspase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp9 caspase 9 involved_in ISO
IEA
IBA		 (PMID:15657060)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:15657060 GO_REF:0000033 GO_REF:0000107 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Casp9_v1 caspase-9-carboxyl-terminal divergent involved_in IBA
IEA		 GO_REF:0000033
GO_REF:0000107		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107
G Chek2 checkpoint kinase 2 involved_in ISO
IEA		 (PMID:12402044), (PMID:12717439), (PMID:18644861)
GO_REF:0000107		 RGD
Ensembl		 PMID:12402044 PMID:12717439 PMID:18644861 GO_REF:0000107 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Crip1 cysteine rich protein 1 involved_in ISS
IBA
ISO		 PMID:20415737
GO_REF:0000033
(PMID:20415737)		 GO_Central
RGD		 PMID:20415737 PMID:20415737 GO_REF:0000033, RGD:8553326 NCBI chr 6:138,047,801...138,055,672
Ensembl chr 6:132,226,746...132,234,620 		JBrowse link
G E2f1 E2F transcription factor 1 involved_in ISO
IEA
ISS		 (PMID:12717439)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12717439 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:163,524,739...163,535,563
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein acts_upstream_of_or_within ISO
IEA		 (PMID:10594026)
GO_REF:0000107		 RGD
Ensembl		 PMID:10594026 GO_REF:0000107 NCBI chr 8:44,683,138...44,699,502
Ensembl chr 8:36,494,289...36,510,571 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO
IEA		 (PMID:18339848)
GO_REF:0000107		 RGD
Ensembl		 PMID:18339848 GO_REF:0000107 NCBI chr 5:158,888,629...158,917,100
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor acts_upstream_of_or_within ISO
IEA		 MGI:1932102 (PMID:11005836)
GO_REF:0000107		 RGD
Ensembl		 PMID:11005836 GO_REF:0000107 NCBI chr16:7,771,311...7,841,895
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Fnip2 folliculin interacting protein 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19137017)		 UniProt
RGD		 PMID:19137017 GO_REF:0000024 NCBI chr 2:166,894,726...167,006,490
Ensembl chr 2:164,598,906...164,707,901 		JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 involved_in ISO (PMID:16269335) RGD PMID:16269335 NCBI chr10:60,512,855...60,517,812
Ensembl chr10:60,011,528...60,019,475 		JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:11854317 RGD:625692 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO
IEA		 (PMID:11602612)
GO_REF:0000107		 RGD
Ensembl		 PMID:11602612 GO_REF:0000107 NCBI chr 4:117,114,631...117,117,793
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO
IEA		 (PMID:11753682)
GO_REF:0000107		 RGD
Ensembl		 PMID:11753682 GO_REF:0000107 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon involved_in ISO (PMID:20188669) RGD PMID:20188669 NCBI chr13:45,264,404...45,290,737
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Mael maelstrom spermatogenic transposon silencer acts_upstream_of_or_within ISO MGI:3795667 (PMID:18694567) RGD PMID:18694567 NCBI chr13:80,990,040...81,029,623
Ensembl chr13:78,457,073...78,496,657 		JBrowse link
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase acts_upstream_of_or_within ISO MGI:2183491 (PMID:14562041) RGD PMID:14562041 NCBI chr 4:150,565,646...150,577,433
Ensembl chr 4:148,894,280...148,904,982 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:15901672)
GO_REF:0000033		 RGD
GO_Central		 PMID:15901672 GO_REF:0000033 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mlh1 mutL homolog 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857946 (PMID:14562041)
GO_REF:0000107		 RGD
Ensembl		 PMID:14562041 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:127,647,389...127,649,324
Ensembl chr 6:121,882,366...121,898,643
Ensembl chr17:121,882,366...121,898,643 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO
IEA		 MGI:1858055|MGI:2680817 (PMID:10097137), (PMID:14744764)
GO_REF:0000107		 RGD
Ensembl		 PMID:10097137 PMID:14744764 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh6 mutS homolog 6 acts_upstream_of_or_within ISO
IEA		 MGI:1858014 (PMID:15324697)
GO_REF:0000107		 RGD
Ensembl		 PMID:15324697 GO_REF:0000107 NCBI chr 6:12,316,190...12,333,505
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:2447604 (PMID:14517295) RGD PMID:14517295 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO MGI:97583 (PMID:17242187) RGD PMID:17242187 NCBI chr15:33,256,912...33,284,522
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
G Pcbp4 poly(rC) binding protein 4 involved_in ISO (PMID:10891498) RGD PMID:10891498 NCBI chr 8:115,971,751...115,981,987
Ensembl chr 8:107,093,013...107,103,276 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 acts_upstream_of_or_within ISO MGI:104798|MGI:2149414 (PMID:17242187) RGD PMID:17242187 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO MGI:2678372 (PMID:12952892) RGD PMID:12952892 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pml PML nuclear body scaffold involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:12402044)
GO_REF:0000107
GO_REF:0000033
MGI:104662|MGI:2429949 (PMID:15626733), (PMID:9806545)		 RGD
Ensembl
GO_Central		 PMID:9806545 PMID:12402044 PMID:15626733 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Polb DNA polymerase beta acts_upstream_of_or_within ISO
IEA		 (PMID:10197627)
GO_REF:0000107		 RGD
Ensembl		 PMID:10197627 GO_REF:0000107 NCBI chr16:76,081,903...76,105,174
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:1857113 (PMID:12604618)		 GO_Central
Ensembl
RGD		 PMID:12604618 GO_REF:0000033 GO_REF:0000107 NCBI chr11:98,544,952...98,762,499
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of ISO
IEA		 MGI:2442925 (PMID:15983387)
GO_REF:0000107		 RGD
Ensembl		 PMID:15983387 GO_REF:0000107 NCBI chr 1:210,917,970...210,983,038
Ensembl chr 1:201,487,136...201,553,608 		JBrowse link
G Sfn stratifin involved_in ISO (PMID:11574543) RGD PMID:11574543 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:16269335)
GO_REF:0000107		 RGD
Ensembl		 PMID:16269335 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of ISO
IEA		 MGI:2387096 (PMID:10811619)
GO_REF:0000107		 RGD
Ensembl		 PMID:10811619 GO_REF:0000107 NCBI chr 2:114,175,534...114,203,663
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO
IEA		 MGI:1857480 (PMID:15642323)
GO_REF:0000107		 RGD
Ensembl		 PMID:15642323 GO_REF:0000107 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO (PMID:17242187) RGD PMID:17242187 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A acts_upstream_of_or_within ISO (PMID:17242187) RGD PMID:17242187 NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:17242187)		 GO_Central
RGD		 PMID:17242187 GO_REF:0000033 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase involved_in ISO
IEA		 (PMID:20188669)
GO_REF:0000107		 RGD
Ensembl		 PMID:20188669 GO_REF:0000107 NCBI chr 5:60,184,076...60,195,979
Ensembl chr 5:55,387,632...55,399,937 		JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3043446 (PMID:15271982)
GO_REF:0000033		 RGD
GO_Central		 PMID:15271982 GO_REF:0000033 NCBI chr 8:70,155,059...70,243,416
Ensembl chr 8:61,259,477...61,347,789 		JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of ISO
IEA		 MGI:4130032 (PMID:19966869)
GO_REF:0000107		 RGD
Ensembl		 PMID:19966869 GO_REF:0000107 NCBI chr 1:175,586,758...175,669,904
Ensembl chr 1:166,152,199...166,235,312 		JBrowse link
G Xpa XPA, DNA damage recognition and repair factor acts_upstream_of_or_within ISO MGI:1857939 (PMID:11005836) RGD PMID:11005836 NCBI chr 5:65,227,281...65,275,784
Ensembl chr 5:60,431,673...60,475,726 		JBrowse link
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aen apoptosis enhancing nuclease involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:18264133)		 UniProt
Ensembl
GO_Central
RGD		 PMID:18264133 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:142,224,499...142,233,902
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO
IEA		 MGI:1336991|MGI:98834 (PMID:15983387)
GO_REF:0000107		 RGD
Ensembl		 PMID:15983387 GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17403783)		 UniProt
Ensembl
RGD		 PMID:17403783 GO_REF:0000024 GO_REF:0000107 NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Bbc3 Bcl-2 binding component 3 acts_upstream_of_or_within ISO MGI:2681654 (PMID:16151013) RGD PMID:16151013 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl3 BCL3, transcription coactivator acts_upstream_of_or_within ISO (PMID:16384933) RGD PMID:16384933 NCBI chr 1:88,599,321...88,613,555
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Brca2 BRCA2, DNA repair associated acts_upstream_of_or_within ISO
IEA		 MGI:2429691|MGI:3052655|MGI:98834 (PMID:15735671), (PMID:17476307)
GO_REF:0000107		 RGD
Ensembl		 PMID:15735671 PMID:17476307 GO_REF:0000107 NCBI chr12:4,895,092...4,939,340
Ensembl chr12:59,819...100,567 		JBrowse link
G Cdip1 cell death-inducing p53 target 1 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:17599062)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:17599062 GO_REF:0000033 GO_REF:0000107 NCBI chr10:11,278,213...11,303,415
Ensembl chr10:10,774,705...10,796,980 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO MGI:1933751 (PMID:12952892) RGD PMID:12952892 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Chek2 checkpoint kinase 2 acts_upstream_of_or_within ISO
IEA		 MGI:2386905 (PMID:10710310)
GO_REF:0000107		 RGD
Ensembl		 PMID:10710310 GO_REF:0000107 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21896779)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21896779 GO_REF:0000024 GO_REF:0000107 NCBI chr20:28,434,938...28,437,037
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Dyrk2 dual specificity tyrosine phosphorylation regulated kinase 2 involved_in ISO (PMID:17349958) RGD PMID:17349958 NCBI chr 7:56,235,276...56,265,741
Ensembl chr 7:54,349,610...54,380,106 		JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:17403783) RGD PMID:17403783 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:1314872|MGI:98834 (PMID:16537918)		 GO_Central
Ensembl
RGD		 PMID:16537918 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:193,937,261...193,988,247
Ensembl chr 2:191,248,817...191,298,902 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 acts_upstream_of_or_within ISO MGI:1314872|MGI:98834 (PMID:16537918) RGD PMID:16537918 NCBI chr 4:68,399,358...68,586,404
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Msh2 mutS homolog 2 acts_upstream_of_or_within ISO
IEA		 MGI:98834 (PMID:10097137)
GO_REF:0000107		 RGD
Ensembl		 PMID:10097137 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator acts_upstream_of_or_within ISO
IEA		 MGI:3784016 (PMID:11896600)
GO_REF:0000107		 RGD
Ensembl		 PMID:11896600 GO_REF:0000107 NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 involved_in ISO
IBA
ISS		 (PMID:19203586)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:19203586 GO_REF:0000024 GO_REF:0000033 NCBI chr13:49,745,003...49,748,088
Ensembl chr13:47,193,086...47,196,335 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within ISO (PMID:10807576) RGD PMID:10807576 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO
IEA		 (PMID:15626733)
GO_REF:0000107		 RGD
Ensembl		 PMID:15626733 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma involved_in ISO (PMID:17245430) RGD PMID:17245430 NCBI chr 6:135,282,947...135,419,591
Ensembl chr 6:129,461,648...129,598,346 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA		 (PMID:14730312)
GO_REF:0000107		 RGD
Ensembl		 PMID:14730312 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rps27l ribosomal protein S27-like involved_in ISO
IEA		 (PMID:17057733), (PMID:18056458)
GO_REF:0000107		 RGD
Ensembl		 PMID:17057733 PMID:18056458 GO_REF:0000107 NCBI chr 8:76,443,658...76,448,593
Ensembl chr 8:67,562,483...67,567,418
Ensembl chr12:67,562,483...67,567,418
Ensembl chr 2:67,562,483...67,567,418 		JBrowse link
G Shisa5 shisa family member 5 acts_upstream_of_or_within ISO
IEA		 (PMID:12135983)
GO_REF:0000107		 RGD
Ensembl		 PMID:12135983 GO_REF:0000107 NCBI chr 8:118,569,975...118,584,880
Ensembl chr 8:109,691,522...109,706,408 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:20100829)
GO_REF:0000107		 RGD
Ensembl		 PMID:20100829 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Snw1 SNW domain containing 1 involved_in ISO (PMID:21460037) RGD PMID:21460037 NCBI chr 6:112,826,374...112,850,459
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
G Tmem109 transmembrane protein 109 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:4453832 (PMID:20060811)		 GO_Central
Ensembl
RGD		 PMID:20060811 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:216,944,516...216,955,091
Ensembl chr 1:207,519,624...207,530,215 		JBrowse link
G Topors TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase acts_upstream_of_or_within ISO
IEA		 (PMID:15735665)
GO_REF:0000107		 RGD
Ensembl		 PMID:15735665 GO_REF:0000107 NCBI chr 5:60,184,076...60,195,979
Ensembl chr 5:55,387,632...55,399,937 		JBrowse link
G Tp53 tumor protein p53 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:16213212), (PMID:17403783)
(PMID:16213212), (PMID:20818388)
MGI:109337|MGI:1096393|MGI:1336991|MGI:1857263|MGI:1926340|MGI:2442925 (PMID:12135983), (PMID:12952892), (PMID:15983387), (PMID:16286009), (PMID:16777961), (PMID:17476307)
GO_REF:0000107
(PMID:14654789), (PMID:14744935)		 RGD
Ensembl		 PMID:12135983 PMID:12952892 PMID:14654789 PMID:14744935 PMID:15983387 More... GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO
IEA		 MGI:1934269 (PMID:17122775)
GO_REF:0000107		 RGD
Ensembl		 PMID:17122775 GO_REF:0000107 NCBI chr11:88,343,647...88,554,543
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tp73 tumor protein p73 involved_in
acts_upstream_of		 ISO
IEA		 (PMID:18174154), (PMID:19490146)
GO_REF:0000107
MGI:2442925|MGI:98834 (PMID:15983387)		 RGD
Ensembl		 PMID:15983387 PMID:18174154 PMID:19490146 GO_REF:0000107 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Uri1 URI1, prefoldin-like chaperone involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:99,783,157...99,845,787
Ensembl chr 1:90,646,393...90,709,026 		JBrowse link
G Usp28 ubiquitin specific peptidase 28 involved_in ISO
ISS		 (PMID:16901786)
GO_REF:0000024		 RGD
UniProt		 PMID:16901786 GO_REF:0000024 NCBI chr 8:58,222,258...58,282,711
Ensembl chr 8:49,325,867...49,386,229 		JBrowse link
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07005775.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Aifm1 apoptosis inducing factor, mitochondria associated 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18056262)		 UniProt
RGD		 PMID:18056262 GO_REF:0000024 NCBI chr  X:132,528,107...132,567,237
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 involved_in ISO
IEA		 (PMID:16407291)
GO_REF:0000107		 RGD
Ensembl		 PMID:16407291 GO_REF:0000107 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Atf4 activating transcription factor 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21159964), (PMID:23624402)		 UniProt
Ensembl
RGD		 PMID:21159964 PMID:23624402 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISO
IEA		 (PMID:19061639)
GO_REF:0000107		 RGD
Ensembl		 PMID:19061639 GO_REF:0000107 NCBI chr 1:190,457,198...190,475,410
Ensembl chr 1:181,026,608...181,044,838 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 involved_in ISO (PMID:16725111) RGD PMID:16725111 NCBI chr10:58,079,710...58,111,279
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18056262)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18056262 GO_REF:0000024 GO_REF:0000107 NCBI chr20:3,680,607...3,693,329
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 acts_upstream_of_or_within ISO
IEA		 MGI:99702|UniProtKB:P10415 (PMID:12847083), (PMID:15776018)
GO_REF:0000107		 RGD
Ensembl		 PMID:12847083 PMID:15776018 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO
IEA		 MGI:1097161|UniProtKB:P10415 (PMID:12847083), (PMID:15776018)
GO_REF:0000107		 RGD
Ensembl		 PMID:12847083 PMID:15776018 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:16407291), (PMID:21159964), (PMID:22761832)		 UniProt
GO_Central
RGD		 PMID:16407291 PMID:21159964 PMID:22761832 GO_REF:0000024 GO_REF:0000033 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO (PMID:15776018) RGD PMID:15776018 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Brsk2 BR serine/threonine kinase 2 involved_in ISO
IEA		 (PMID:22713462)
GO_REF:0000107		 RGD
Ensembl		 PMID:22713462 GO_REF:0000107 NCBI chr 1:206,465,040...206,518,156
Ensembl chr 1:197,035,633...197,088,092 		JBrowse link
G Casp12 caspase 12 involved_in
acts_upstream_of_or_within		 NAS
ISO
IEA		 PMID:10638761
(PMID:10638761), (PMID:12097332)
MGI:1097161|MGI:99702 (PMID:12847083)
GO_REF:0000107		 RGD
Ensembl		 PMID:10638761 PMID:12097332 PMID:12847083 PMID:10638761 GO_REF:0000107, RGD:10047306 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp4 caspase 4 involved_in ISO (PMID:15123740) RGD PMID:15123740 NCBI chr 8:10,883,817...10,919,978
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:9531536)		 Ensembl
RGD		 PMID:9531536 GO_REF:0000107 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 involved_in ISO
IEA		 (PMID:19109178)
GO_REF:0000107		 RGD
Ensembl		 PMID:19109178 GO_REF:0000107 NCBI chr 3:126,796,131...126,799,352
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISO
IEA		 (PMID:18281285)
GO_REF:0000107		 RGD
Ensembl		 PMID:18281285 GO_REF:0000107 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:21159964), (PMID:23624402), (PMID:9531536)
MGI:2179046 (PMID:11854325)
GO_REF:0000033
(PMID:15322075), (PMID:18940792), (PMID:20829347)		 UniProt
Ensembl
RGD
GO_Central		 PMID:9531536 PMID:11854325 PMID:15322075 PMID:18940792 PMID:20829347 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 involved_in ISO (PMID:19122239) RGD PMID:19122239 NCBI chr 3:85,636,890...85,679,620
Ensembl chr 3:65,232,697...65,272,719 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:2177666 (PMID:11430819) RGD PMID:11430819 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:11146108), (PMID:19328063)		 GO_Central
Ensembl
RGD		 PMID:11146108 PMID:19328063 GO_REF:0000033 GO_REF:0000107 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:9755171)		 GO_Central
Ensembl
RGD		 PMID:9755171 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:186,153,115...186,174,521
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19752026)		 UniProt
Ensembl
RGD		 PMID:19752026 GO_REF:0000024 GO_REF:0000107 NCBI chr15:20,974,771...21,010,170
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (PMID:23028846) RGD PMID:23028846 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Ins2 insulin 2 acts_upstream_of_or_within ISO
IEA		 MGI:1857572 (PMID:11854325)
GO_REF:0000107		 RGD
Ensembl		 PMID:11854325 GO_REF:0000107 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:19752026)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19752026 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO
IEA
IBA		 (PMID:12050113)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:12050113 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of ISO
IEA		 MGI:2181360 (PMID:20811152)
GO_REF:0000107		 RGD
Ensembl		 PMID:20811152 GO_REF:0000107 NCBI chr12:12,793,957...12,799,156
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:16407291) RGD PMID:16407291 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO
IEA		 (PMID:21030605)
GO_REF:0000107		 RGD
Ensembl		 PMID:21030605 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Qrich1 glutamine-rich 1 involved_in ISO
IEA		 (PMID:33384352)
GO_REF:0000107		 RGD
Ensembl		 PMID:33384352 GO_REF:0000107 NCBI chr 8:118,095,435...118,135,001
Ensembl chr 8:109,217,376...109,261,359 		JBrowse link
G Rnf186 ring finger protein 186 involved_in ISO
IEA
IBA		 (PMID:23896122)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:23896122 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:156,493,750...156,494,974
Ensembl chr 5:151,210,492...151,211,716 		JBrowse link
G Selenok selenoprotein K involved_in ISO
IEA		 (PMID:20692228)
GO_REF:0000107		 RGD
Ensembl		 PMID:20692228 GO_REF:0000107 NCBI chr16:5,158,601...5,167,183
Ensembl chr16:5,152,066...5,159,188 		JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of ISO
IEA		 MGI:102851 (PMID:20811152)
GO_REF:0000107		 RGD
Ensembl		 PMID:20811152 GO_REF:0000107 NCBI chr10:80,854,890...80,935,781
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
G Syvn1 synoviolin 1 acts_upstream_of ISO MGI:2679656 (PMID:15611074) RGD PMID:15611074 NCBI chr 1:212,766,736...212,775,426
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 acts_upstream_of_or_within ISO MGI:3052422 (PMID:15304216) RGD PMID:15304216 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Tmem117 transmembrane protein 117 involved_in ISO
IEA
IBA		 (PMID:28285135)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:28285135 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:127,636,862...128,098,944
Ensembl chr 7:125,757,591...126,219,690 		JBrowse link
G Tmem238l transmembrane protein 238 like involved_in ISO (PMID:33112233) RGD PMID:33112233 NCBI chr10:52,148,188...52,161,234 JBrowse link
G Tp53 tumor protein p53 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16407291)		 Ensembl
RGD		 PMID:16407291 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15775988)		 UniProt
Ensembl
RGD		 PMID:15775988 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:161,269,939...161,275,533
Ensembl chr 3:140,809,043...140,814,497 		JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K acts_upstream_of_or_within IMP PMID:18710920 MGI PMID:18710920 RGD:8554156 NCBI chr14:43,011,681...43,077,825
Ensembl chr14:42,658,016...42,718,630 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA		 (PMID:19328063)
GO_REF:0000107		 RGD
Ensembl		 PMID:19328063 GO_REF:0000107 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2k4 mitogen activated protein kinase kinase 4 involved_in ISO (PMID:24705900) RGD PMID:24705900 NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Pdcd10 programmed cell death 10 involved_in ISO
IEA		 UniProtKB:O00506 (PMID:22652780)
GO_REF:0000107		 RGD
Ensembl		 PMID:22652780 GO_REF:0000107 NCBI chr 2:162,602,516...162,644,690
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Stk25 serine/threonine kinase 25 involved_in ISO
IEA		 UniProtKB:Q9BUL8 (PMID:22652780)
GO_REF:0000107		 RGD
Ensembl		 PMID:22652780 GO_REF:0000107 NCBI chr 9:101,609,218...101,621,458
Ensembl chr 9:94,161,836...94,174,244 		JBrowse link
intrinsic apoptotic signaling pathway in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf2 activating transcription factor 2 involved_in ISO MGI:1857283 (PMID:17189429) RGD PMID:17189429 NCBI chr 3:79,125,814...79,202,896
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO
IEA		 (PMID:20436456)
GO_REF:0000107		 RGD
Ensembl		 PMID:20436456 GO_REF:0000107 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO
IEA		 (PMID:20935145)
GO_REF:0000107		 RGD
Ensembl		 PMID:20935145 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
intrinsic apoptotic signaling pathway in response to nitrosative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit3 DNA-damage inducible transcript 3 involved_in ISO
IEA		 (PMID:14752510)
GO_REF:0000107		 RGD
Ensembl		 PMID:14752510 GO_REF:0000107 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 involved_in ISO
IEA		 (PMID:21716255)
GO_REF:0000107		 RGD
Ensembl		 PMID:21716255 GO_REF:0000107 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 acts_upstream_of_or_within ISS
ISO		 GO_REF:0000024
MGI:2180186 (PMID:10827969)		 UniProt
RGD		 PMID:10827969 GO_REF:0000024 NCBI chr 3:70,710,862...70,845,569
Ensembl chr 3:50,302,877...50,437,214 		JBrowse link
intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 acts_upstream_of ISO
IEA		 MGI:98834|MGI:99702 (PMID:16571598)
GO_REF:0000107		 RGD
Ensembl		 PMID:16571598 GO_REF:0000107 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
intrinsic apoptotic signaling pathway in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member IMP protein:altered expression:liver (rat) RGD PMID:29589772 RGD:14975297 NCBI chr12:40,610,244...40,643,220
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Arl6ip5 ARF like GTPase 6 interacting protein 5 involved_in ISO
IEA		 (PMID:18387645)
GO_REF:0000107		 RGD
Ensembl		 PMID:18387645 GO_REF:0000107 NCBI chr 4:131,365,320...131,395,311
Ensembl chr 4:129,810,645...129,838,608 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO (PMID:12855558) RGD PMID:12855558 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:23568032), (PMID:23979599)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23568032 PMID:23979599 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:16085184)		 GO_Central
RGD		 PMID:16085184 GO_REF:0000033 NCBI chr12:38,716,668...38,731,285
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Diablol1 diablo, IAP-binding mitochondrial protein like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:147,029,329...147,030,698
Ensembl chr 5:141,744,961...141,746,356 		JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within ISO
IEA		 MGI:2158814 (PMID:11562367), (PMID:15663476)
GO_REF:0000107
MGI:2158814 (PMID:16373599)		 RGD
Ensembl		 PMID:11562367 PMID:15663476 PMID:16373599 GO_REF:0000107 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gskip GSK3B interacting protein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:25920809)		 UniProt
Ensembl
RGD		 PMID:25920809 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:130,357,241...130,373,221
Ensembl chr 6:124,586,070...124,609,100 		JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:15659221 RGD:1641883 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G LOC134486345 serine/threonine-protein kinase 24-like involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:18,234,608...18,236,670 JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:21771788), (PMID:26095851)
GO_REF:0000107
GO_REF:0000033
(PMID:18948261)		 RGD
Ensembl
GO_Central		 PMID:18948261 PMID:21771788 PMID:26095851 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapt microtubule-associated protein tau IDA RGD PMID:12420308 RGD:8158111 NCBI chr10:89,638,618...89,736,108
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Melk maternal embryonic leucine zipper kinase acts_upstream_of_or_within ISO
IEA		 (PMID:18948261)
GO_REF:0000107		 RGD
Ensembl		 PMID:18948261 GO_REF:0000107 NCBI chr 5:63,336,151...63,396,254
Ensembl chr 5:58,540,449...58,600,937 		JBrowse link
G Nox1 NADPH oxidase 1 acts_upstream_of ISO
IEA		 MGI:3616995 (PMID:19661248)
GO_REF:0000107		 RGD
Ensembl		 PMID:19661248 GO_REF:0000107 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18541534)		 UniProt
Ensembl
RGD		 PMID:18541534 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:77,113,464...77,144,145
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO
IEA		 (PMID:21030605)
GO_REF:0000107		 RGD
Ensembl		 PMID:21030605 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Rnf7 ring finger protein 7 acts_upstream_of_or_within ISO (PMID:10082581) RGD PMID:10082581 NCBI chr 8:105,918,395...105,927,643
Ensembl chr 8:97,038,840...97,047,824 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO
IEA		 MGI:1857480 (PMID:15642323)
GO_REF:0000107		 RGD
Ensembl		 PMID:15642323 GO_REF:0000107 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stk24 serine/threonine kinase 24 involved_in ISO
IEA
ISS		 (PMID:19604147)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19604147 GO_REF:0000024 GO_REF:0000107 NCBI chr15:104,770,556...104,866,524
Ensembl chr15:98,365,791...98,460,553 		JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:3043446 (PMID:15271982)
GO_REF:0000033		 RGD
GO_Central		 PMID:15271982 GO_REF:0000033 NCBI chr 8:70,155,059...70,243,416
Ensembl chr 8:61,259,477...61,347,789 		JBrowse link
G Zfp622 zinc finger protein 622 involved_in ISO (PMID:21771788) RGD PMID:21771788 NCBI chr 2:78,205,655...78,224,888
Ensembl chr 2:76,335,609...76,493,898 		JBrowse link
mitochondrial outer membrane permeabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO
IEA		 MGI:1929260 (PMID:20436477)
GO_REF:0000107		 RGD
Ensembl		 PMID:20436477 GO_REF:0000107 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 involved_in ISO
IEA
ISS		 (PMID:18188704)
GO_REF:0000107		 RGD
Ensembl		 PMID:18188704 PMID:18188704 GO_REF:0000107, RGD:8553738 NCBI chr 1:252,973,818...252,980,873
Ensembl chr 1:243,024,614...243,031,653 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO
IEA
IBA		 (PMID:18371312)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:18371312 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bnip3-ps3 BCL2 interacting protein 3, pseudogene 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:45,660,760...45,661,337
Ensembl chr  X:41,782,209...41,782,898
Ensembl chr  X:41,782,209...41,782,898 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 acts_upstream_of_or_within ISO
IEA		 (PMID:11700312)
GO_REF:0000107		 RGD
Ensembl		 PMID:11700312 GO_REF:0000107 NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Rhot1 ras homolog family member T1 involved_in ISO (PMID:12482879) RGD PMID:12482879 NCBI chr10:65,685,687...65,760,682
Ensembl chr10:65,170,560...65,262,804 		JBrowse link
G Rhot2 ras homolog family member T2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:12482879)		 UniProt
RGD		 PMID:12482879 GO_REF:0000024 NCBI chr10:15,363,467...15,369,263
Ensembl chr10:14,858,956...14,864,751 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO
ISS		 (PMID:31015432)
GO_REF:0000024		 RGD
UniProt		 PMID:31015432 GO_REF:0000024 NCBI chr15:2,512,214...2,526,105
Ensembl chr15:2,463,056...2,476,553 		JBrowse link
negative regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatf apoptosis antagonizing transcription factor acts_upstream_of_or_within ISO MGI:1930187 (PMID:17488777) RGD PMID:17488777 NCBI chr10:69,796,502...69,889,671
Ensembl chr10:69,299,037...69,392,201 		JBrowse link
G Asah2 N-acylsphingosine amidohydrolase 2 involved_in ISO
ISS		 (PMID:15946935)
GO_REF:0000024		 RGD
UniProt		 PMID:15946935 GO_REF:0000024 NCBI chr 1:239,278,994...239,386,598
Ensembl chr 1:229,865,662...229,939,162 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO
IEA		 MGI:2675387 (PMID:18436203)
GO_REF:0000107		 RGD
Ensembl		 PMID:18436203 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in
acts_upstream_of_or_within		 ISO (PMID:20097879)
(PMID:11546872)		 RGD PMID:11546872 PMID:20097879 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor involved_in ISO RNAcentral:URS000055128B_10090 (PMID:26708520) RGD PMID:26708520 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (PMID:11546872) RGD PMID:11546872 NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger acts_upstream_of_or_within ISO
IEA		 MGI:99161 (PMID:11290297)
GO_REF:0000107		 RGD
Ensembl		 PMID:11290297 GO_REF:0000107 NCBI chr17:86,240,683...86,250,044
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Cdk11b cyclin-dependent kinase 11B acts_upstream_of_or_within ISO MGI:3043373 (PMID:15060143) RGD PMID:15060143 NCBI chr 5:171,495,042...171,521,143
Ensembl chr 5:166,212,829...166,238,876 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16193064)		 UniProt
RGD		 PMID:16193064 GO_REF:0000024 NCBI chr 3:161,170,295...161,217,073
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Cth cystathionine gamma-lyase acts_upstream_of_or_within ISO
IEA		 (PMID:22244329)
GO_REF:0000107		 RGD
Ensembl		 PMID:22244329 GO_REF:0000107 NCBI chr 2:249,634,731...249,661,066
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within ISO
IEA		 MGI:1858008|MGI:2148567|MGI:98957 (PMID:15131783), (PMID:20454446)
GO_REF:0000107		 RGD
Ensembl		 PMID:15131783 PMID:20454446 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 involved_in ISO
IEA		 UniProtKB:P35411 (PMID:10869418)
GO_REF:0000107		 RGD
Ensembl		 PMID:10869418 GO_REF:0000107 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 involved_in IGI PMID:10869418 ARUK-UCL PMID:10869418 RGD:4892026 NCBI chr 8:128,661,294...128,679,048
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Ep300 E1A binding protein p300 IMP cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within ISO
IEA		 MGI:4888719 (PMID:21209208)
GO_REF:0000107		 RGD
Ensembl		 PMID:21209208 GO_REF:0000107 NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:130,633,348...130,659,168 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (PMID:25590961) RGD PMID:25590961 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 8:117,167,045...117,187,652
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 IMP RGD PMID:25633408 RGD:13507311 NCBI chr 2:198,430,920...198,468,874
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:23690069 RGD:13792722 NCBI chr 1:211,010,259...211,031,013
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 acts_upstream_of_or_within ISO
IEA		 (PMID:15731106)
GO_REF:0000107		 RGD
Ensembl		 PMID:15731106 GO_REF:0000107 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Igbp1 immunoglobulin binding protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:2448686|MGI:3056510 (PMID:15499020)
GO_REF:0000107		 RGD
Ensembl		 PMID:15499020 GO_REF:0000107 NCBI chr  X:69,622,925...69,645,167
Ensembl chr  X:65,582,821...65,606,049 		JBrowse link
G Ing2 inhibitor of growth family, member 2 acts_upstream_of_or_within ISO MGI:4879096 (PMID:21124965) RGD PMID:21124965 NCBI chr16:51,305,311...51,316,177
Ensembl chr16:44,575,597...44,583,482 		JBrowse link
G Madd MAP-kinase activating death domain acts_upstream_of_or_within ISO (PMID:14735464) RGD PMID:14735464 NCBI chr 3:97,570,141...97,613,688
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 acts_upstream_of_or_within ISO MGI:104798 (PMID:16260493) RGD PMID:16260493 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO
IEA		 (PMID:10756100)
GO_REF:0000107		 RGD
Ensembl		 PMID:10756100 GO_REF:0000107 NCBI chr 7:122,406,350...122,416,602
Ensembl chr 7:120,526,732...120,536,982 		JBrowse link
G Maz MYC associated zinc finger protein involved_in ISO
IEA		 (PMID:25487955)
GO_REF:0000107		 RGD
Ensembl		 PMID:25487955 GO_REF:0000107 NCBI chr 1:191,060,271...191,065,722
Ensembl chr 1:181,629,729...181,650,408 		JBrowse link
G Mdm2 MDM2 proto-oncogene IMP caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Meis3 Meis homeobox 3 acts_upstream_of_or_within ISO
IEA		 (PMID:21059917)
GO_REF:0000107		 RGD
Ensembl		 PMID:21059917 GO_REF:0000107 NCBI chr 1:85,986,602...86,000,873
Ensembl chr 1:76,861,924...76,872,691 		JBrowse link
G Mir146a microRNA 146a acts_upstream_of ISO (PMID:28433754) RGD PMID:28433754 NCBI chr10:28,349,996...28,350,090
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir210 microRNA 210 involved_in ISO (PMID:26780211) RGD PMID:26780211 NCBI chr 1:205,755,923...205,756,032
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mnt MAX network transcriptional repressor acts_upstream_of_or_within ISO MGI:2678322 (PMID:12970171) RGD PMID:12970171 NCBI chr10:60,197,654...60,213,221
Ensembl chr10:59,699,585...59,714,835 		JBrowse link
G Mrtfa myocardin related transcription factor A acts_upstream_of_or_within ISO
IEA		 (PMID:12019265)
GO_REF:0000107		 RGD
Ensembl		 PMID:12019265 GO_REF:0000107 NCBI chr 7:114,424,481...114,594,594
Ensembl chr 7:112,544,312...112,714,418 		JBrowse link
G Nanos3 nanos C2HC-type zinc finger 3 acts_upstream_of_or_within ISO MGI:2682607|MGI:99702 (PMID:18436203) RGD PMID:18436203 NCBI chr19:40,889,531...40,893,699
Ensembl chr19:23,985,504...23,988,932 		JBrowse link
G Nog noggin acts_upstream_of_or_within ISO
IEA		 MGI:1862000 (PMID:16712836)
GO_REF:0000107		 RGD
Ensembl		 PMID:16712836 GO_REF:0000107 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 involved_in ISO (PMID:19429166) RGD PMID:19429166 NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Pam16 presequence translocase associated motor 16 acts_upstream_of_or_within ISO (PMID:20719856) RGD PMID:20719856 NCBI chr10:11,449,316...11,457,071
Ensembl chr10:10,943,001...10,950,649 		JBrowse link
G Pcgf2 polycomb group ring finger 2 acts_upstream_of_or_within ISO MGI:88174 (PMID:11290297) RGD PMID:11290297 NCBI chr10:83,178,926...83,191,610
Ensembl chr10:82,683,553...82,693,406 		JBrowse link
G Ppef2 protein phosphatase with EF-hand domain 2 involved_in ISO
IEA		 (PMID:20674765)
GO_REF:0000107		 RGD
Ensembl		 PMID:20674765 GO_REF:0000107 NCBI chr14:16,081,706...16,115,903
Ensembl chr14:15,797,435...15,831,491 		JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO
IEA		 MGI:109284 (PMID:15148382)
GO_REF:0000107		 RGD
Ensembl		 PMID:15148382 GO_REF:0000107 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO MGI:1202717 (PMID:15148382) RGD PMID:15148382 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Qars1 glutaminyl-tRNA synthetase 1 involved_in ISO
IEA		 (PMID:11096076)
GO_REF:0000107		 RGD
Ensembl		 PMID:11096076 GO_REF:0000107 NCBI chr 8:118,086,243...118,094,274
Ensembl chr 8:109,207,705...109,215,739 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IMP PMID:24027266 ARUK-UCL PMID:24027266 RGD:14397580 NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO
IBA		 (PMID:21075086)
GO_REF:0000033		 RGD
GO_Central		 PMID:21075086 GO_REF:0000033 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Tnf tumor necrosis factor acts_upstream_of_or_within ISO
IEA		 RNAcentral:URS0000330617_9606 (PMID:31124343)
GO_REF:0000107		 RGD
Ensembl		 PMID:31124343 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Wnt16 Wnt family member 16 involved_in ISO
IEA		 (PMID:17200136)
GO_REF:0000107		 RGD
Ensembl		 PMID:17200136 GO_REF:0000107 NCBI chr 4:51,786,728...51,797,137
Ensembl chr 4:50,820,968...50,831,380 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO
IEA		 MGI:88276|MGI:96571 (PMID:20454446)
GO_REF:0000107		 RGD
Ensembl		 PMID:20454446 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
negative regulation of death-inducing signaling complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nol3 nucleolar protein 3 involved_in IDA PMID:12191471
PMID:15383280		 UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:21785459) RGD PMID:21785459 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2l1 Bcl2-like 1 involved_in ISO
ISS		 (PMID:29507230)
GO_REF:0000024		 RGD
UniProt		 PMID:29507230 GO_REF:0000024 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 involved_in ISO
IEA		 (PMID:16940180)
GO_REF:0000107		 RGD
Ensembl		 PMID:16940180 GO_REF:0000107 NCBI chr 5:62,613,652...62,619,019
Ensembl chr 5:57,817,832...57,824,390 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO		 PMID:15665855
(PMID:15665855)		 RGD PMID:15665855 PMID:15665855 RGD:1558627 NCBI chr 3:98,408,240...98,449,104
Ensembl chr 3:77,952,540...77,993,456 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:1341830|MGI:99682 (PMID:22240901)
GO_REF:0000107		 RGD
Ensembl		 PMID:22240901 GO_REF:0000107 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IEA
IBA		 (PMID:15102845)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:15102845 GO_REF:0000033 GO_REF:0000107 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:12150907), (PMID:20625543) RGD PMID:12150907 PMID:20625543 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma involved_in ISO (PMID:23453807) RGD PMID:23453807 NCBI chr  X:157,358,279...157,397,563
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO
IEA		 (PMID:21857923)
GO_REF:0000107		 RGD
Ensembl		 PMID:21857923 GO_REF:0000107 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Ngf nerve growth factor involved_in NAS PMID:21266243 ParkinsonsUK-UCL PMID:21266243 RGD:10047230 NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23453807)
UniProtKB:P58281 (PMID:23453807)		 ParkinsonsUK-UCL
Ensembl
RGD		 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021) RGD PMID:14652021 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:2181360 (PMID:20811152)
GO_REF:0000107		 RGD
Ensembl		 PMID:20811152 GO_REF:0000107 NCBI chr12:12,793,957...12,799,156
Ensembl chr12:7,757,865...7,763,064 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:21113145)
(PMID:10973942), (PMID:11439185), (PMID:12150907), (PMID:21113145), (PMID:23453807)		 ParkinsonsUK-UCL
Ensembl
RGD		 PMID:10973942 PMID:11439185 PMID:12150907 PMID:21113145 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 involved_in ISO
IEA		 (PMID:21216966)
GO_REF:0000107		 RGD
Ensembl		 PMID:21216966 GO_REF:0000107 NCBI chr 3:177,056,588...177,106,424
Ensembl chr 3:156,638,769...156,687,504 		JBrowse link
G Selenos selenoprotein S involved_in ISO
IEA		 (PMID:17210132)
GO_REF:0000107		 RGD
Ensembl		 PMID:17210132 GO_REF:0000107 NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:119,659,751...119,669,833 		JBrowse link
G Syvn1 synoviolin 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:12459480), (PMID:17059562)
GO_REF:0000107
MGI:2679656 (PMID:15611074)		 RGD
Ensembl		 PMID:12459480 PMID:15611074 PMID:17059562 GO_REF:0000107 NCBI chr 1:212,766,736...212,775,426
Ensembl chr 1:203,339,619...203,346,152 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in
acts_upstream_of_or_within		 ISO (PMID:21075086)
MGI:1913418 (PMID:22240901)		 RGD PMID:21075086 PMID:22240901 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Txndc12 thioredoxin domain containing 12 acts_upstream_of_or_within ISO
IEA		 (PMID:18628206)
GO_REF:0000107		 RGD
Ensembl		 PMID:18628206 GO_REF:0000107 NCBI chr 5:128,815,471...128,841,574
Ensembl chr 5:123,586,781...123,612,870 		JBrowse link
G Wfs1 wolframin ER transmembrane glycoprotein involved_in ISO
IEA		 (PMID:16571599)
GO_REF:0000107		 RGD
Ensembl		 PMID:16571599 GO_REF:0000107 NCBI chr14:78,035,205...78,059,718
Ensembl chr14:73,810,404...73,835,602 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
IMP		 (PMID:19135031)
GO_REF:0000107
PMID:20625543		 RGD
Ensembl		 PMID:19135031 PMID:20625543 GO_REF:0000107, RGD:10047191 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hyou1 hypoxia up-regulated 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17116640)		 Ensembl
RGD		 PMID:17116640 GO_REF:0000107 NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:O15354 (PMID:17116640), (PMID:23453807)		 Ensembl
RGD		 PMID:17116640 PMID:23453807 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA		 (PMID:9884026)
GO_REF:0000107		 RGD
Ensembl		 PMID:9884026 GO_REF:0000107 NCBI chr 3:63,387,378...63,506,980
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Ar androgen receptor involved_in
acts_upstream_of		 IEA
ISO
ISS		 GO_REF:0000107
(PMID:21310825)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21310825 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:67,135,317...67,304,476
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Birc6 baculoviral IAP repeat-containing 6 involved_in ISO
IEA		 (PMID:14765125)
GO_REF:0000107		 RGD
Ensembl		 PMID:14765125 GO_REF:0000107 NCBI chr 6:26,474,843...26,668,275
Ensembl chr 6:20,722,922...20,916,434 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:15070745)		 Ensembl
RGD		 PMID:15070745 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:22266862), (PMID:9208847)
GO_REF:0000107
MGI:109324|MGI:2154952 (PMID:22675671)		 RGD
Ensembl		 PMID:9208847 PMID:22266862 PMID:22675671 GO_REF:0000107 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Cttn cortactin acts_upstream_of_or_within ISO
IEA		 MGI:1924375 (PMID:22660580)
GO_REF:0000107		 RGD
Ensembl		 PMID:22660580 GO_REF:0000107 NCBI chr 1:209,029,048...209,064,577
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Dab2 DAB adaptor protein 2 acts_upstream_of_or_within ISO (PMID:15734730) RGD PMID:15734730 NCBI chr 2:57,241,947...57,294,893
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Fcmr Fc mu receptor acts_upstream_of_or_within ISO (PMID:15632112) RGD PMID:15632112 NCBI chr13:44,889,628...44,903,926
Ensembl chr13:42,337,414...42,351,653 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO
IEA		 MGI:104995 (PMID:15288121)
GO_REF:0000107		 RGD
Ensembl		 PMID:15288121 GO_REF:0000107 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO
IEA		 MGI:104990 (PMID:15288121)
GO_REF:0000107		 RGD
Ensembl		 PMID:15288121 GO_REF:0000107 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in ISO
IEA		 (PMID:16636664)
GO_REF:0000107		 RGD
Ensembl		 PMID:16636664 GO_REF:0000107 NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Htt huntingtin involved_in IMP
IEA
ISO		 GO_REF:0000107
(PMID:19240112)		 Ensembl
RGD		 PMID:19240112 PMID:17124493 GO_REF:0000107, RGD:6902918 NCBI chr14:80,070,456...80,219,668
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA
IDA		 (PMID:16942485)
GO_REF:0000107
PMID:17023532		 RGD
Ensembl		 PMID:16942485 PMID:17023532 GO_REF:0000107, RGD:1600072 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (PMID:23468852) RGD PMID:23468852 NCBI chr13:44,949,989...44,958,714
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:10429671) RGD PMID:10429671 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Itga6 integrin subunit alpha 6 involved_in ISO (PMID:21310825) RGD PMID:21310825 NCBI chr 3:77,012,168...77,097,076
Ensembl chr 3:56,617,268...56,689,428 		JBrowse link
G Itgav integrin subunit alpha V involved_in ISO
IEA		 (PMID:10708943)
GO_REF:0000107		 RGD
Ensembl		 PMID:10708943 GO_REF:0000107 NCBI chr 3:89,245,382...89,333,512
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Lgals3 galectin 3 involved_in ISO
IBA
IEA		 (PMID:22761016)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:22761016 GO_REF:0000033 GO_REF:0000107 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lmna lamin A/C acts_upstream_of_or_within ISO (PMID:21151901) RGD PMID:21151901 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:50,067,978...50,076,715
Ensembl chr19:33,158,056...33,166,445 		JBrowse link
G Mir142 microRNA 142 involved_in ISO UniProtKB:P01137 (PMID:26572508) RGD PMID:26572508 NCBI chr10:73,055,104...73,055,190
Ensembl chr10:72,557,857...72,557,967 		JBrowse link
G Mir199a2 microRNA 199a-2 involved_in ISO (PMID:22821565) RGD PMID:22821565 NCBI chr13:77,116,225...77,116,334
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO
IBA		 (PMID:9560245)
GO_REF:0000033		 RGD
GO_Central		 PMID:9560245 GO_REF:0000033 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO
IEA		 (PMID:21828096)
GO_REF:0000107		 RGD
Ensembl		 PMID:21828096 GO_REF:0000107 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 acts_upstream_of_or_within ISO (PMID:12897128) RGD PMID:12897128 NCBI chr 3:143,848,404...144,156,674
Ensembl chr 3:123,396,497...123,703,930 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
ISS		 (PMID:21785459)
GO_REF:0000024		 RGD
ParkinsonsUK-UCL		 PMID:21785459 GO_REF:0000024 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Peli3 pellino E3 ubiquitin protein ligase family member 3 acts_upstream_of_or_within ISO
IEA		 (PMID:24113711)
GO_REF:0000107
MGI:5441750 (PMID:23950925)		 RGD
Ensembl		 PMID:23950925 PMID:24113711 GO_REF:0000107 NCBI chr 1:211,659,416...211,672,280
Ensembl chr 1:202,232,228...202,242,857 		JBrowse link
G Phip pleckstrin homology domain interacting protein acts_upstream_of_or_within ISO
IEA		 (PMID:17636024)
GO_REF:0000107		 RGD
Ensembl		 PMID:17636024 GO_REF:0000107 NCBI chr 8:92,656,890...92,771,098
Ensembl chr 8:83,781,465...83,894,283 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (PMID:15259009) RGD PMID:15259009 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Psme3 proteasome activator subunit 3 involved_in ISO (PMID:18309296) RGD PMID:18309296 NCBI chr10:86,757,933...86,765,719
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Rb1cc1 RB1-inducible coiled-coil 1 acts_upstream_of_or_within ISO
IEA		 MGI:3690329 (PMID:17015619)
GO_REF:0000107		 RGD
Ensembl		 PMID:17015619 GO_REF:0000107 NCBI chr 5:17,948,522...18,012,434
Ensembl chr 5:13,161,648...13,225,560 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:21310825)
GO_REF:0000107
(PMID:22244329)		 RGD
Ensembl		 PMID:21310825 PMID:22244329 GO_REF:0000107 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:21525013)
GO_REF:0000107
MGI:104798|MGI:109200 (PMID:22089168)		 RGD
Ensembl		 PMID:21525013 PMID:22089168 GO_REF:0000107 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 acts_upstream_of_or_within ISO (PMID:11493700) RGD PMID:11493700 NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Scg2 secretogranin II involved_in ISO (PMID:14970115) RGD PMID:14970115 NCBI chr 9:88,251,531...88,257,208
Ensembl chr 9:80,803,075...80,821,097 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISO
IEA		 (PMID:21586138)
GO_REF:0000107		 RGD
Ensembl		 PMID:21586138 GO_REF:0000107 NCBI chr16:33,746,396...33,912,127
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 involved_in ISO
IEA		 (PMID:21586138)
GO_REF:0000107		 RGD
Ensembl		 PMID:21586138 GO_REF:0000107 NCBI chr 2:145,063,847...145,081,675
Ensembl chr 2:142,914,003...142,931,950 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IBA		 (PMID:19767770)
GO_REF:0000033		 RGD
GO_Central		 PMID:19767770 GO_REF:0000033 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 involved_in IMP PMID:21965303 BHF-UCL PMID:21965303 RGD:14974246 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA		 (PMID:18625725)
GO_REF:0000107		 RGD
Ensembl		 PMID:18625725 GO_REF:0000107 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA		 (PMID:11009421)
GO_REF:0000107		 RGD
Ensembl		 PMID:11009421 GO_REF:0000107 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (PMID:11567634) RGD PMID:11567634 NCBI chr 5:171,889,134...171,891,824
Ensembl chr 5:166,606,909...166,609,599 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:21828096) RGD PMID:21828096 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator acts_upstream_of_or_within ISO
IEA		 MGI:95484 (PMID:17980593)
GO_REF:0000107		 RGD
Ensembl		 PMID:17980593 GO_REF:0000107 NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
G Zmynd11 zinc finger, MYND-type containing 11 involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr17:65,226,907...65,323,278
Ensembl chr17:60,543,077...60,631,902 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 7:64,782,618...64,799,624
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within ISO MGI:99702 (PMID:8358790) RGD PMID:8358790 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Col2a1 collagen type II alpha 1 chain acts_upstream_of_or_within ISO
IEA		 MGI:2152978 (PMID:9299161)
GO_REF:0000107		 RGD
Ensembl		 PMID:9299161 GO_REF:0000107 NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO
IEA		 (PMID:10666185)
GO_REF:0000107		 RGD
Ensembl		 PMID:10666185 GO_REF:0000107 NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO
IEA		 MGI:2677796 (PMID:22411810)
GO_REF:0000107		 RGD
Ensembl		 PMID:22411810 GO_REF:0000107 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of_or_within ISO
IEA		 (PMID:18322241), (PMID:18971423)
GO_REF:0000107		 RGD
Ensembl		 PMID:18322241 PMID:18971423 GO_REF:0000107 NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857803 (PMID:15817220)		 GO_Central
RGD		 PMID:15817220 GO_REF:0000033 NCBI chr 5:9,646,599...9,884,609
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:174,754,772...174,938,035
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:150,090,535...150,218,855
Ensembl chr 5:144,806,577...144,934,518 		JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:23,991,431...24,235,132
Ensembl chr 1:22,172,275...22,415,976 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO
IEA		 MGI:1859647 (PMID:16956603)
GO_REF:0000107		 RGD
Ensembl		 PMID:16956603 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (PMID:15070677) RGD PMID:15070677 NCBI chr17:4,487,716...4,490,701 JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO
IEA		 (PMID:17167422)
GO_REF:0000107		 RGD
Ensembl		 PMID:17167422 GO_REF:0000107 NCBI chr  X:17,193,291...17,209,462
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO
IEA		 (PMID:10921886)
GO_REF:0000107		 RGD
Ensembl		 PMID:10921886 GO_REF:0000107 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gfral GDNF family receptor alpha like acts_upstream_of_or_within ISO (PMID:16086688) RGD PMID:16086688 NCBI chr 8:85,798,337...85,843,705
Ensembl chr 8:76,918,657...76,959,425 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within ISO (PMID:8950980) RGD PMID:8950980 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Klf4 KLF transcription factor 4 involved_in ISO
IEA		 (PMID:20551324)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551324 GO_REF:0000107 NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:72,520,616...72,748,395
Ensembl chr 8:63,625,221...63,851,983 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA		 UniProtKB:Q62862 (PMID:20551324)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551324 GO_REF:0000107 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (PMID:20921992) RGD PMID:20921992 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO (PMID:9115640) RGD PMID:9115640 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:20125124)
GO_REF:0000107		 RGD
Ensembl		 PMID:20125124 GO_REF:0000107 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 acts_upstream_of_or_within ISO
IEA		 (PMID:11050396)
GO_REF:0000107		 RGD
Ensembl		 PMID:11050396 GO_REF:0000107 NCBI chr 5:14,128,628...14,255,099
Ensembl chr 5:9,346,040...9,415,476 		JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:10518215) RGD PMID:10518215 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within ISO
IEA		 (PMID:12574163)
GO_REF:0000107		 RGD
Ensembl		 PMID:12574163 GO_REF:0000107 NCBI chr 9:67,908,277...67,927,224
Ensembl chr 9:60,414,182...60,433,084 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO
IEA		 (PMID:10449030)
GO_REF:0000107		 RGD
Ensembl		 PMID:10449030 GO_REF:0000107 NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO
IEA		 (PMID:10666185), (PMID:10748004)
GO_REF:0000107		 RGD
Ensembl		 PMID:10666185 PMID:10748004 GO_REF:0000107 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO (PMID:18469807) RGD PMID:18469807 NCBI chr20:29,240,639...29,307,270
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Bcl2l1 Bcl2-like 1 acts_upstream_of_or_within ISO (PMID:26582200) RGD PMID:26582200 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO (PMID:23415688) RGD PMID:23415688 NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Caps calcyphosine acts_upstream_of_or_within ISO (PMID:12466268) RGD PMID:12466268 NCBI chr 9:1,630,871...1,632,758
Ensembl chr 9:1,544,719...1,545,647 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:18202225)
GO_REF:0000107
(PMID:26582200)		 RGD
Ensembl		 PMID:18202225 PMID:26582200 GO_REF:0000107 NCBI chr 9:67,679,502...67,747,226
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:18846110) RGD PMID:18846110 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Faim Fas apoptotic inhibitory molecule involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:10075978)		 GO_Central
Ensembl
RGD		 PMID:10075978 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:108,423,259...108,445,365
Ensembl chr 8:99,542,405...99,560,562 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 acts_upstream_of_or_within
involved_in		 ISO
IEA
IBA		 (PMID:26582200)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:26582200 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:132,512,095...132,539,192
Ensembl chr 7:130,633,348...130,659,168 		JBrowse link
G Faiml Fas apoptotic inhibitory molecule like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:108,671,391...108,689,538
Ensembl chr 8:99,791,981...99,810,228 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO
IEA		 (PMID:10903502)
GO_REF:0000107		 RGD
Ensembl		 PMID:10903502 GO_REF:0000107 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:12221075)		 Ensembl
RGD		 PMID:12221075 GO_REF:0000107 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:109,842,870...109,846,048
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18846110)		 UniProt
Ensembl
RGD		 PMID:18846110 GO_REF:0000024 GO_REF:0000107 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hgf hepatocyte growth factor acts_upstream_of_or_within ISO
IEA		 (PMID:15314156)
GO_REF:0000107		 RGD
Ensembl		 PMID:15314156 GO_REF:0000107 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hmgb2 high mobility group box 2 acts_upstream_of_or_within ISO MGI:2387671 (PMID:19139395) RGD PMID:19139395 NCBI chr16:37,721,374...37,723,950
Ensembl chr16:32,710,658...32,713,140
Ensembl chr 1:32,710,658...32,713,140 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO
IEA		 (PMID:18202225)
GO_REF:0000107		 RGD
Ensembl		 PMID:18202225 GO_REF:0000107 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein acts_upstream_of_or_within ISO MGI:1916885 (PMID:20053891) RGD PMID:20053891 NCBI chr 1:256,704,087...256,727,661
Ensembl chr 1:246,762,472...246,786,408 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP PMID:12191471
PMID:15383280		 UniProt PMID:12191471 PMID:15383280 RGD:631884, RGD:10047289 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 involved_in
acts_upstream_of_or_within		 ISO
IBA
IEA		 (PMID:10442631)
(PMID:10588860)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:10442631 PMID:10588860 GO_REF:0000033 GO_REF:0000107 NCBI chr13:87,190,189...87,199,811
Ensembl chr13:84,654,870...84,667,499 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO
IEA		 MGI:2388026|MGI:95484|MGI:99255 (PMID:16365167)
GO_REF:0000107		 RGD
Ensembl		 PMID:16365167 GO_REF:0000107 NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase involved_in ISO
IBA
ISS		 (PMID:15069192)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:15069192 GO_REF:0000024 GO_REF:0000033 NCBI chr10:68,238,273...68,301,225
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Rnf34 ring finger protein 34 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:15069192)		 UniProt
GO_Central
Ensembl
RGD		 PMID:15069192 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:39,364,461...39,385,391
Ensembl chr12:33,703,673...33,724,586 		JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA		 (PMID:18835034)
GO_REF:0000107		 RGD
Ensembl		 PMID:18835034 GO_REF:0000107 NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO
IEA		 (PMID:9391078)
GO_REF:0000107		 RGD
Ensembl		 PMID:9391078 GO_REF:0000107 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 involved_in ISO
IEA
IBA
ISS		 (PMID:21107705)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:21107705 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:83,320,972...83,338,469
Ensembl chr 9:75,871,835...75,889,069 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 involved_in ISO
IEA		 (PMID:12167698)
GO_REF:0000107		 RGD
Ensembl		 PMID:12167698 GO_REF:0000107 NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 acts_upstream_of_or_within ISO (PMID:12466268) RGD PMID:12466268 NCBI chr 1:208,269,844...208,285,823
Ensembl chr 1:198,840,453...198,856,309 		JBrowse link
G Ybx3 Y box binding protein 3 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:165,129,758...165,153,161 		JBrowse link
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISO
IEA		 (PMID:21177249)
GO_REF:0000107		 RGD
Ensembl		 PMID:21177249 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO UniProtKB:Q99LX0 (PMID:14652021) RGD PMID:14652021 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA		 (PMID:21177249), (PMID:23261939)
GO_REF:0000107		 RGD
Ensembl		 PMID:21177249 PMID:23261939 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eno1 enolase 1 involved_in ISO UniProtKB:Q01986 (PMID:15459207) RGD PMID:15459207 NCBI chr 5:166,002,867...166,014,252
Ensembl chr 5:160,719,951...160,731,336
Ensembl chr 3:160,719,951...160,731,336 		JBrowse link
G Hyou1 hypoxia up-regulated 1 involved_in IDA
IBA
IEA
ISO		 PMID:11231630
GO_REF:0000033
GO_REF:0000107
(PMID:10037731)		 GO_Central
Ensembl
RGD		 PMID:10037731 PMID:11231630 GO_REF:0000033 GO_REF:0000107, RGD:10047348 NCBI chr 8:53,602,882...53,614,998
Ensembl chr 8:44,706,263...44,718,186 		JBrowse link
G Kdm6a lysine demethylase 6A IMP RGD PMID:30887465 RGD:151665136 NCBI chr  X:6,920,374...7,060,027
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IGI
IMP		 PMID:15459207 CAFA PMID:15459207 PMID:15459207 RGD:12793039, RGD:12793039 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA PMID:10590251 UniProt PMID:10590251 RGD:10047155 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in IEA
ISO		 GO_REF:0000107
(PMID:30496354)		 Ensembl
RGD		 PMID:30496354 GO_REF:0000107 NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA		 (PMID:24553947)
GO_REF:0000107		 RGD
Ensembl		 PMID:24553947 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (PMID:21075086) RGD PMID:21075086 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19911006)		 Ensembl
RGD		 PMID:19911006 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO (PMID:11684014) RGD PMID:11684014 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:12011449)
(PMID:21567405)		 RGD PMID:12011449 PMID:21567405 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:21883093) RGD PMID:21883093 NCBI chr  X:12,152,346...12,165,983
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Fignl1 fidgetin-like 1 acts_upstream_of_or_within ISO (PMID:20886204) RGD PMID:20886204 NCBI chr14:90,573,090...90,595,342
Ensembl chr14:86,368,675...86,377,455 		JBrowse link
G G2e3 G2/M-phase specific E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:3808723 (PMID:18511420) RGD PMID:18511420 NCBI chr 6:74,498,801...74,530,703
Ensembl chr 6:68,764,185...68,793,924 		JBrowse link
G Gcg glucagon involved_in ISO (PMID:19915011) RGD PMID:19915011 NCBI chr 3:67,522,489...67,531,533
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Hdac1 histone deacetylase 1 acts_upstream_of_or_within ISO MGI:1097691 (PMID:21093383) RGD PMID:21093383 NCBI chr 5:147,138,328...147,165,387
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 acts_upstream_of_or_within ISO MGI:108086 (PMID:21093383) RGD PMID:21093383 NCBI chr20:42,101,815...42,126,486
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hells helicase, lymphoid specific acts_upstream_of_or_within ISO
IEA		 MGI:2178586 (PMID:11325543)
GO_REF:0000107		 RGD
Ensembl		 PMID:11325543 GO_REF:0000107 NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO
IEA		 UniProtKB:P37840 (PMID:22045699)
GO_REF:0000107		 RGD
Ensembl		 PMID:22045699 GO_REF:0000107 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Ivns1abp influenza virus NS1A binding protein acts_upstream_of_or_within ISO
IEA		 MGI:4820513 (PMID:15485691)
GO_REF:0000107		 RGD
Ensembl		 PMID:15485691 GO_REF:0000107 NCBI chr13:65,977,069...65,996,685
Ensembl chr13:63,427,041...63,446,701 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 acts_upstream_of_or_within ISO
IEA		 (PMID:10098834)
GO_REF:0000107		 RGD
Ensembl		 PMID:10098834 GO_REF:0000107 NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22984561)		 Ensembl
RGD		 PMID:22984561 GO_REF:0000107 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor involved_in ISO
IEA		 (PMID:16322561)
GO_REF:0000107		 RGD
Ensembl		 PMID:16322561 GO_REF:0000107 NCBI chr 5:172,102,369...172,114,168
Ensembl chr 5:166,820,161...166,831,949 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IMP
IBA		 PMID:15383280
GO_REF:0000033		 GO_Central PMID:15383280 GO_REF:0000033, RGD:10047289 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISO
IEA		 (PMID:16839884)
GO_REF:0000107		 RGD
Ensembl		 PMID:16839884 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO		 GO_REF:0000024
(PMID:16839884)		 ParkinsonsUK-UCL
RGD		 PMID:16839884 GO_REF:0000024 NCBI chr11:94,097,559...94,124,915
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA		 (PMID:15087508)
GO_REF:0000107		 RGD
Ensembl		 PMID:15087508 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO
IEA		 (PMID:22984561)
GO_REF:0000107		 RGD
Ensembl		 PMID:22984561 GO_REF:0000107 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISO
ISS		 (PMID:19228691)
GO_REF:0000024		 RGD
UniProt		 PMID:19228691 GO_REF:0000024 NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Rtkn2 rhotekin 2 involved_in ISO
IEA		 (PMID:26124677)
GO_REF:0000107		 RGD
Ensembl		 PMID:26124677 GO_REF:0000107 NCBI chr20:20,535,553...20,608,863
Ensembl chr20:20,525,256...20,609,951 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO
IBA		 (PMID:19767770)
GO_REF:0000033		 RGD
GO_Central		 PMID:19767770 GO_REF:0000033 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Uri1 URI1, prefoldin-like chaperone involved_in ISO
IBA		 (PMID:17936702)
GO_REF:0000033		 RGD
GO_Central		 PMID:17936702 GO_REF:0000033 NCBI chr 1:99,783,157...99,845,787
Ensembl chr 1:90,646,393...90,709,026 		JBrowse link
G Vdac2 voltage-dependent anion channel 2 involved_in ISO (PMID:12881569) RGD PMID:12881569 NCBI chr15:2,512,214...2,526,105
Ensembl chr15:2,463,056...2,476,553 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Armc10 armadillo repeat containing 10 involved_in ISO (PMID:17904127) RGD PMID:17904127 NCBI chr 4:14,291,211...14,306,799
Ensembl chr 4:13,395,207...13,414,548 		JBrowse link
G Cep63 centrosomal protein 63 acts_upstream_of_or_within ISO MGI:98834 (PMID:26158450) RGD PMID:26158450 NCBI chr 8:112,041,586...112,093,061
Ensembl chr 8:103,162,700...103,214,177 		JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO
IEA		 (PMID:17310983)
GO_REF:0000107		 RGD
Ensembl		 PMID:17310983 GO_REF:0000107 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mdm4 MDM4 regulator of p53 involved_in ISO (PMID:12101245) RGD PMID:12101245 NCBI chr13:46,922,236...47,068,241
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:18829576) RGD PMID:18829576 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:23985028)
GO_REF:0000107		 RGD
Ensembl		 PMID:23985028 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Pttg1ip PTTG1 interacting protein acts_upstream_of_or_within ISO (PMID:24506068) RGD PMID:24506068 NCBI chr20:11,029,608...11,047,395
Ensembl chr20:11,030,015...11,047,316 		JBrowse link
G Rrm2b ribonucleotide reductase regulatory TP53 inducible subunit M2B acts_upstream_of_or_within ISO
IEA		 MGI:2672883 (PMID:12858174)
GO_REF:0000107		 RGD
Ensembl		 PMID:12858174 GO_REF:0000107 NCBI chr 7:70,962,008...70,993,726
Ensembl chr 7:69,078,291...69,108,633 		JBrowse link
G Rrn3 RRN3 homolog, RNA polymerase I transcription factor acts_upstream_of_or_within ISO
IEA		 MGI:3584037 (PMID:15989966)
GO_REF:0000107		 RGD
Ensembl		 PMID:15989966 GO_REF:0000107 NCBI chr10:2,637,016...2,672,338
Ensembl chr10:2,129,978...2,165,663 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (PMID:24523556) RGD PMID:24523556 NCBI chr 2:236,411,194...236,445,225
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr3 atypical chemokine receptor 3 involved_in ISO
IEA		 (PMID:20388803)
GO_REF:0000107		 RGD
Ensembl		 PMID:20388803 GO_REF:0000107 NCBI chr 9:98,247,300...98,258,877
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO
IEA		 (PMID:15983387)
GO_REF:0000107		 RGD
Ensembl		 PMID:15983387 GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:16608847) RGD PMID:16608847 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO
IEA		 MGI:5428930 (PMID:26219591)
GO_REF:0000107		 RGD
Ensembl		 PMID:26219591 GO_REF:0000107 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO
IEA		 (PMID:23352644)
GO_REF:0000107		 RGD
Ensembl		 PMID:23352644 GO_REF:0000107 NCBI chr15:51,622,519...51,637,911
Ensembl chr15:45,212,803...45,227,636 		JBrowse link
G Cdkn2d cyclin dependent kinase inhibitor 2D involved_in ISO
IEA		 (PMID:15750620)
GO_REF:0000107		 RGD
Ensembl		 PMID:15750620 GO_REF:0000107 NCBI chr 8:28,108,036...28,110,809
Ensembl chr 8:19,831,866...19,834,674 		JBrowse link
G Clu clusterin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16113678)		 UniProt
Ensembl
RGD		 PMID:16113678 GO_REF:0000024 GO_REF:0000107 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 involved_in ISO
IEA		 (PMID:20388803)
GO_REF:0000107		 RGD
Ensembl		 PMID:20388803 GO_REF:0000107 NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Ddias DNA damage-induced apoptosis suppressor involved_in ISO
IEA		 (PMID:24214091)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:24214091 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:156,318,559...156,342,869
Ensembl chr 1:146,906,154...146,930,462 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 involved_in ISO (PMID:14561758) RGD PMID:14561758 NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Snai1 snail family transcriptional repressor 1 involved_in ISO
IEA		 (PMID:15314165)
GO_REF:0000107		 RGD
Ensembl		 PMID:15314165 GO_REF:0000107 NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:15314165) RGD PMID:15314165 NCBI chr11:99,686,934...99,690,349
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Tmem161a transmembrane protein 161A involved_in ISO (PMID:16551573) RGD PMID:16551573 NCBI chr16:19,272,433...19,282,173
Ensembl chr16:19,238,487...19,248,087 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 acts_upstream_of_or_within ISO (PMID:11598139) RGD PMID:11598139 NCBI chr15:57,562,217...57,568,968
Ensembl chr15:51,146,154...51,159,625 		JBrowse link
G Trim32 tripartite motif-containing 32 involved_in ISO (PMID:18632609) RGD PMID:18632609 NCBI chr 5:84,020,604...84,031,483
Ensembl chr 5:78,999,389...79,022,018 		JBrowse link
G Usp47 ubiquitin specific peptidase 47 acts_upstream_of_or_within ISO
IEA		 MGI:4130032 (PMID:19966869)
GO_REF:0000107		 RGD
Ensembl		 PMID:19966869 GO_REF:0000107 NCBI chr 1:175,586,758...175,669,904
Ensembl chr 1:166,152,199...166,235,312 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 involved_in ISO
IEA		 (PMID:15983387)
GO_REF:0000107		 RGD
Ensembl		 PMID:15983387 GO_REF:0000107 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,070,689...65,117,845 		JBrowse link
G Bcl2l12 Bcl2 like 12 acts_upstream_of_or_within ISO
IEA		 (PMID:20837658)
GO_REF:0000107		 RGD
Ensembl		 PMID:20837658 GO_REF:0000107 NCBI chr 1:104,608,753...104,617,472
Ensembl chr 1:95,472,272...95,480,991 		JBrowse link
G Cd44 CD44 molecule involved_in ISO
IEA		 (PMID:17045821)
GO_REF:0000107		 RGD
Ensembl		 PMID:17045821 GO_REF:0000107 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in ISO
IBA
ISS		 (PMID:17045821)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
BHF-UCL		 PMID:17045821 GO_REF:0000024 GO_REF:0000033 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Kdm1a lysine demethylase 1A involved_in ISO
IEA		 (PMID:17805299)
GO_REF:0000107		 RGD
Ensembl		 PMID:17805299 GO_REF:0000107 NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:29295817)		 UniProt
RGD		 PMID:29295817 GO_REF:0000024 NCBI chr 3:65,090,640...65,128,768
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:17045821) RGD PMID:17045821 NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11672522)		 Ensembl
RGD		 PMID:11672522 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO
IEA		 (PMID:15735003)
GO_REF:0000107		 RGD
Ensembl		 PMID:15735003 GO_REF:0000107 NCBI chr12:46,928,273...46,930,766
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
G Zfp385a zinc finger protein 385A involved_in ISO
IEA		 (PMID:17719541)
GO_REF:0000107		 RGD
Ensembl		 PMID:17719541 GO_REF:0000107 NCBI chr 7:136,327,393...136,354,017
Ensembl chr 7:134,448,921...134,475,548 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car3 carbonic anhydrase 3 IMP RGD PMID:29559661 RGD:408427357 NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:24947010) RGD PMID:24947010 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA
IMP		 (PMID:17579517)
GO_REF:0000107		 RGD
Ensembl		 PMID:17579517 PMID:17579517 GO_REF:0000107, RGD:8693356 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q99497 (PMID:24947010)		 Ensembl
RGD		 PMID:24947010 GO_REF:0000107 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Trap1 TNF receptor-associated protein 1 involved_in IMP PMID:17579517 ParkinsonsUK-UCL PMID:17579517 RGD:8693356 NCBI chr10:11,971,259...12,005,306
Ensembl chr10:11,464,821...11,498,981 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:22711822) RGD PMID:22711822 NCBI chr 2:176,358,909...176,416,178
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within ISO
IEA		 MGI:1857135 (PMID:16571598)
GO_REF:0000107		 RGD
Ensembl		 PMID:16571598 GO_REF:0000107 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Epo erythropoietin involved_in ISO
IEA		 (PMID:14569084)
GO_REF:0000107		 RGD
Ensembl		 PMID:14569084 GO_REF:0000107 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Ptger2 prostaglandin E receptor 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr15:20,694,765...20,708,475
Ensembl chr15:18,217,285...18,228,714 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ybx3 Y box binding protein 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22711822)		 Ensembl
RGD		 PMID:22711822 GO_REF:0000107 NCBI chr 4:166,861,180...166,884,532
Ensembl chr 4:165,129,758...165,153,161 		JBrowse link
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb2 bradykinin receptor B2 acts_upstream_of_or_within ISO
IEA		 MGI:98834|MGI:99702 (PMID:16571598)
GO_REF:0000107		 RGD
Ensembl		 PMID:16571598 GO_REF:0000107 NCBI chr 6:130,237,055...130,267,205
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa2 acetyl-CoA acyltransferase 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:18371312)		 Ensembl
UniProt
RGD		 PMID:18371312 GO_REF:0000024 GO_REF:0000107 NCBI chr18:70,620,310...70,648,417
Ensembl chr18:68,345,012...68,373,249 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO
IEA		 (PMID:15901672)
GO_REF:0000107		 RGD
Ensembl		 PMID:15901672 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:15901672), (PMID:9393856)
GO_REF:0000114		 RGD
ComplexPortal		 PMID:9393856 PMID:15901672 GO_REF:0000114 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO
IEA		 (PMID:27098698)
GO_REF:0000107		 RGD
Ensembl		 PMID:27098698 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G ENSRNOG00000063076 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 7:88,803,047...88,804,403 JBrowse link
G ENSRNOG00000063289 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr10:100,153,638...100,154,558 JBrowse link
G ENSRNOG00000066174 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 1:201,787,072...201,792,824 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO
IEA		 MGI:104995 (PMID:15288121)
GO_REF:0000107		 RGD
Ensembl		 PMID:15288121 GO_REF:0000107 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:20625543) RGD PMID:20625543 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO
IEA		 (PMID:19096392)
GO_REF:0000107		 RGD
Ensembl		 PMID:19096392 GO_REF:0000107 NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Mpv17l MPV17 mitochondrial inner membrane protein like involved_in ISO (PMID:22306510) RGD PMID:22306510 NCBI chr10:2,495,605...2,532,448
Ensembl chr10:1,988,136...2,007,649 		JBrowse link
G Slc25a31 solute carrier family 25 member 31 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:125,623,331...125,639,155
Ensembl chr 2:123,695,408...123,710,795 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:52,805,521...52,809,316
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:19154410)		 UniProt
GO_Central
RGD		 PMID:19154410 GO_REF:0000024 GO_REF:0000033 NCBI chr  X:120,897,616...120,900,683
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Slc25a5-ps9 solute carrier family 25 member 5, pseudogene 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:117,110,744...117,111,944
Ensembl chr 3:96,656,151...96,657,400 		JBrowse link
G Slc35f6 solute carrier family 35, member F6 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19154410)		 UniProt
Ensembl
RGD		 PMID:19154410 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:31,445,738...31,457,580
Ensembl chr 6:25,725,819...25,737,730 		JBrowse link
G Tmem14a transmembrane protein 14A involved_in ISO (PMID:21723035) RGD PMID:21723035 NCBI chr 9:31,137,011...31,148,794
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463 		JBrowse link
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 involved_in ISO (PMID:14752510) RGD PMID:14752510 NCBI chr 5:60,638,404...60,649,315
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:14752510) RGD PMID:14752510 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:136,589,623...136,593,278
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:27525436 ARUK-UCL PMID:27525436 RGD:13601987 NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of ISO (PMID:25590961) RGD PMID:25590961 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gpx1 glutathione peroxidase 1 acts_upstream_of_or_within ISO
IEA		 MGI:2158814 (PMID:16373599)
GO_REF:0000107		 RGD
Ensembl		 PMID:16373599 GO_REF:0000107 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:15731106)		 Ensembl
RGD		 PMID:15731106 GO_REF:0000107 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA		 (PMID:23043106)
GO_REF:0000107		 RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr10:46,669,721...46,675,768
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:50,067,978...50,076,715
Ensembl chr19:33,158,056...33,166,445 		JBrowse link
G Mir29b1 microRNA 29b-1 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr 4:60,618,334...60,618,414
Ensembl chr 4:59,650,986...59,651,067 		JBrowse link
G Mir29b2 microRNA 29b-2 involved_in ISO (PMID:19956414) RGD PMID:19956414 NCBI chr13:109,098,831...109,098,911
Ensembl chr13:106,570,367...106,570,456 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 involved_in ISO
IEA		 (PMID:23043106)
GO_REF:0000107		 RGD
Ensembl		 PMID:23043106 GO_REF:0000107 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nme5 NME/NM23 family member 5 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:12788088)		 GO_Central
RGD		 PMID:12788088 GO_REF:0000033 NCBI chr18:26,437,705...26,454,828
Ensembl chr18:26,163,555...26,180,794 		JBrowse link
G Nol3 nucleolar protein 3 involved_in ISO (PMID:15004034) RGD PMID:15004034 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of ISO (PMID:22523093) RGD PMID:22523093 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISO
ISS		 (PMID:26095851)
GO_REF:0000024		 RGD
UniProt		 PMID:26095851 GO_REF:0000024 NCBI chr14:85,491,223...85,496,884
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,361,379...21,362,147
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO
IEA		 (PMID:17317627)
GO_REF:0000107		 RGD
Ensembl		 PMID:17317627 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO
IEA		 (PMID:12551919)
GO_REF:0000107		 RGD
Ensembl		 PMID:12551919 GO_REF:0000107 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in IMP
IEA
ISO		 PMID:23392669
GO_REF:0000107
UniProtKB:Q9ES19 (PMID:23392669)		 Ensembl
RGD		 PMID:23392669 PMID:23392669 GO_REF:0000107, RGD:10047168 NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Cpe carboxypeptidase E IMP RGD PMID:25426952 RGD:405650601 NCBI chr16:29,796,707...29,908,647
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21752258)		 Ensembl
RGD		 PMID:21752258 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Fbxo7 F-box protein 7 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:26310625)
GO_REF:0000107
(PMID:25029497)		 RGD
Ensembl		 PMID:25029497 PMID:26310625 GO_REF:0000107 NCBI chr 7:19,696,951...19,725,180
Ensembl chr 7:17,809,231...17,837,530 		JBrowse link
G Fgf2 fibroblast growth factor 2 IMP RGD PMID:25426952 RGD:405650601 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fzd1 frizzled class receptor 1 involved_in ISO (PMID:21752258) RGD PMID:21752258 NCBI chr 4:30,265,074...30,269,472
Ensembl chr 4:29,310,091...29,312,643
Ensembl chr 4:29,310,091...29,312,643 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISO
IEA		 (PMID:24899725)
GO_REF:0000107		 RGD
Ensembl		 PMID:24899725 GO_REF:0000107 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Il10 interleukin 10 involved_in ISO
IEA		 ComplexPortal:CPX-1134 (PMID:21857966)
GO_REF:0000107		 RGD
Ensembl		 PMID:21857966 GO_REF:0000107 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Nono non-POU domain containing, octamer-binding involved_in ISO
IEA		 (PMID:15790595)
GO_REF:0000107		 RGD
Ensembl		 PMID:15790595 GO_REF:0000107 NCBI chr  X:70,594,116...70,611,976
Ensembl chr  X:66,554,098...66,571,952 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(PMID:24899725)
(PMID:15790595), (PMID:16632486), (PMID:23743200)		 ParkinsonsUK-UCL
RGD		 PMID:15790595 PMID:16632486 PMID:23743200 PMID:24899725 GO_REF:0000024 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA		 (PMID:16632486)
GO_REF:0000107		 RGD
Ensembl		 PMID:16632486 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
IGI
ISS		 (PMID:17314283)
(PMID:23858059)
GO_REF:0000107
PMID:23392669
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:17314283 PMID:23858059 PMID:23392669 GO_REF:0000024 GO_REF:0000107, RGD:10047168 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr10:106,416,056...106,420,982
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Wnt1 Wnt family member 1 involved_in ISO
IEA		 (PMID:21752258)
GO_REF:0000107		 RGD
Ensembl		 PMID:21752258 GO_REF:0000107 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
negative regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18977203)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18977203 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Arrb2 arrestin, beta 2 IMP RGD PMID:19171933 RGD:5510006 NCBI chr10:55,645,539...55,653,485
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in ISO
IEA		 (PMID:15901672)
GO_REF:0000107		 RGD
Ensembl		 PMID:15901672 GO_REF:0000107 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in ISO (PMID:15901672), (PMID:9393856)
GO_REF:0000114		 RGD
ComplexPortal		 PMID:9393856 PMID:15901672 GO_REF:0000114 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l2 Bcl2-like 2 IDA RGD PMID:10724126 RGD:14394498 NCBI chr15:32,326,686...32,337,834
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Fxn frataxin involved_in ISO (PMID:16608849) RGD PMID:16608849 NCBI chr 1:231,300,457...231,323,989
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein involved_in ISO (PMID:18417609) RGD PMID:18417609 NCBI chr16:12,907,062...12,918,149
Ensembl chr16:12,885,553...12,897,879 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
IEA		 (PMID:12221075)
GO_REF:0000107		 RGD
Ensembl		 PMID:12221075 GO_REF:0000107 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Hgf hepatocyte growth factor involved_in ISO
IEA		 (PMID:20655899)
GO_REF:0000107		 RGD
Ensembl		 PMID:20655899 GO_REF:0000107 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A acts_upstream_of_or_within ISO
IEA		 (PMID:21856340)
GO_REF:0000107		 RGD
Ensembl		 PMID:21856340 GO_REF:0000107 NCBI chr 8:130,391,658...130,400,888
Ensembl chr 8:121,514,156...121,523,443 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B IMP RGD PMID:16397188 RGD:1626654 NCBI chr20:3,859,756...3,863,800
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18977203)		 UniProt
RGD		 PMID:18977203 GO_REF:0000024 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Lmna lamin A/C acts_upstream_of_or_within ISO (PMID:21151901) RGD PMID:21151901 NCBI chr 2:176,237,564...176,265,301
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Matcap1 microtubule associated tyrosine carboxypeptidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:50,067,978...50,076,715
Ensembl chr19:33,158,056...33,166,445 		JBrowse link
G Mfn2 mitofusin 2 IMP RGD PMID:18006463 RGD:12738362 NCBI chr 5:163,587,463...163,617,363
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IDA
IBA
ISO		 PMID:10590251
GO_REF:0000033
(PMID:15004034)		 GO_Central
RGD		 PMID:15004034 PMID:10590251 GO_REF:0000033, RGD:10047155 NCBI chr19:50,066,493...50,068,175
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16839884)
(PMID:21149567)		 ParkinsonsUK-UCL
Ensembl
RGD		 PMID:16839884 PMID:21149567 GO_REF:0000024 GO_REF:0000107 NCBI chr11:84,612,943...84,690,025
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Pam16 presequence translocase associated motor 16 IDA RGD PMID:24069394 RGD:13462066 NCBI chr10:11,449,316...11,457,071
Ensembl chr10:10,943,001...10,950,649 		JBrowse link
G Parl presenilin associated, rhomboid-like involved_in ISS
ISO		 GO_REF:0000024
(PMID:16839884)		 ParkinsonsUK-UCL
RGD		 PMID:16839884 GO_REF:0000024 NCBI chr11:94,097,559...94,124,915
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Ppif peptidylprolyl isomerase F involved_in ISS
ISO		 GO_REF:0000024
(PMID:19228691)		 UniProt
RGD		 PMID:19228691 GO_REF:0000024 NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
G Prelid1 PRELI domain containing 1 involved_in ISO (PMID:23931759) RGD PMID:23931759 NCBI chr17:9,310,471...9,313,511
Ensembl chr17:9,305,361...9,308,407 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA
ISS		 (PMID:19880420), (PMID:23453807)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
ParkinsonsUK-UCL		 PMID:19880420 PMID:23453807 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Psmd10 proteasome 26S subunit, non-ATPase 10 involved_in ISO
IEA
ISS		 (PMID:19729910)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19729910 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:109,445,291...109,453,605
Ensembl chr  X:104,656,812...104,665,097 		JBrowse link
G Triap1 TP53 regulated inhibitor of apoptosis 1 involved_in ISO
IEA		 (PMID:23931759)
GO_REF:0000107		 RGD
Ensembl		 PMID:23931759 GO_REF:0000107 NCBI chr12:46,928,273...46,930,766
Ensembl chr12:41,267,549...41,270,042 		JBrowse link
negative regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir221 microRNA 221 involved_in ISO (PMID:18246122) RGD PMID:18246122 NCBI chr  X:6,023,182...6,023,290
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir222 microRNA 222 involved_in ISO (PMID:18246122) RGD PMID:18246122 NCBI chr  X:6,022,621...6,022,723
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISS
ISO		 GO_REF:0000024
(PMID:21785459)		 ParkinsonsUK-UCL
RGD		 PMID:21785459 GO_REF:0000024 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tmbim6 transmembrane BAX inhibitor motif containing 6 acts_upstream_of_or_within ISO MGI:3052422 (PMID:15304216) RGD PMID:15304216 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
neuron intrinsic apoptotic signaling pathway in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Daxx death-domain associated protein involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q99683 (PMID:15983381)		 Ensembl
RGD		 PMID:15983381 GO_REF:0000107 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 involved_in ISO
IEA		 UniProtKB:Q9UER7 (PMID:15983381)
GO_REF:0000107		 RGD
Ensembl		 PMID:15983381 GO_REF:0000107 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
positive regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07025928.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 4:51,682,224...51,682,961 JBrowse link
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO
IEA		 MGI:2155985 (PMID:10845921)
GO_REF:0000107		 RGD
Ensembl		 PMID:10845921 GO_REF:0000107 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15105833 RGD:2313858 NCBI chr10:55,456,923...55,469,239
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within ISO
IEA		 MGI:1889507 (PMID:16183742)
GO_REF:0000107		 RGD
Ensembl		 PMID:16183742 GO_REF:0000107 NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO
IEA		 (PMID:8918887)
GO_REF:0000107		 RGD
Ensembl		 PMID:8918887 GO_REF:0000107 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bmf Bcl2 modifying factor acts_upstream_of_or_within ISO (PMID:11546872) RGD PMID:11546872 NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta acts_upstream_of_or_within ISO (PMID:17367784) RGD PMID:17367784 NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Casp2 caspase 2 acts_upstream_of_or_within ISO
IEA		 MGI:1889507 (PMID:16183742)
GO_REF:0000107		 RGD
Ensembl		 PMID:16183742 GO_REF:0000107 NCBI chr 4:72,116,265...72,134,023
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Ccn2 cellular communication network factor 2 IMP RGD PMID:19625611 RGD:2314487 NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1889507 (PMID:16183742)
GO_REF:0000033		 RGD
GO_Central		 PMID:16183742 GO_REF:0000033 NCBI chr 7:31,827,131...31,839,796
Ensembl chr 7:29,798,586...29,952,907 		JBrowse link
G Ctsc cathepsin C acts_upstream_of_or_within ISO
IEA		 MGI:107285 (PMID:20435891)
GO_REF:0000107		 RGD
Ensembl		 PMID:20435891 GO_REF:0000107 NCBI chr 1:151,440,860...151,472,430
Ensembl chr 1:142,028,392...142,060,387 		JBrowse link
G Ctsh cathepsin H involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:109553 (PMID:20435891)		 GO_Central
Ensembl
RGD		 PMID:20435891 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Dab2ip DAB2 interacting protein involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19903888)		 UniProt
Ensembl
RGD		 PMID:19903888 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:39,312,745...39,483,730
Ensembl chr 3:18,915,290...19,086,280 		JBrowse link
G Daxx death-domain associated protein acts_upstream_of_or_within ISO MGI:104662 (PMID:10684855) RGD PMID:10684855 NCBI chr20:4,971,973...4,978,062
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 acts_upstream_of_or_within ISO MGI:3574590 (PMID:15680327) RGD PMID:15680327 NCBI chr17:26,354,247...26,364,953
Ensembl chr17:26,148,633...26,215,720 		JBrowse link
G ENSRNOG00000064602 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr13:63,590,086...63,591,393 JBrowse link
G ENSRNOG00000068437 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr 6:120,369,117...120,369,706 JBrowse link
G Fas Fas cell surface death receptor involved_in ISO (PMID:11096076) RGD PMID:11096076 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Hsf1 heat shock transcription factor 1 IMP RGD PMID:21192280 RGD:10403035 NCBI chr 7:110,076,710...110,103,665
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:10918594), (PMID:11337497) RGD PMID:10918594 PMID:11337497 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO (PMID:12370360) RGD PMID:12370360 NCBI chr13:44,949,989...44,958,714
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 acts_upstream_of_or_within ISO
IEA		 UniProtKB:Q8WYH8 (PMID:21750715)
GO_REF:0000107		 RGD
Ensembl		 PMID:21750715 GO_REF:0000107 NCBI chr10:55,900,610...55,912,975
Ensembl chr10:55,401,982...55,414,114 		JBrowse link
G Ing5 inhibitor of growth family, member 5 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:2144284 (PMID:21750715)		 GO_Central
Ensembl
RGD		 PMID:21750715 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:101,772,845...101,793,734
Ensembl chr 9:94,326,548...94,344,220 		JBrowse link
G Inhbb inhibin subunit beta B acts_upstream_of_or_within ISO
IEA		 MGI:98957 (PMID:20454446)
GO_REF:0000107		 RGD
Ensembl		 PMID:20454446 GO_REF:0000107 NCBI chr13:33,083,671...33,089,373
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO
IEA		 (PMID:15012602)
GO_REF:0000107		 RGD
Ensembl		 PMID:15012602 GO_REF:0000107 NCBI chr 1:236,408,905...236,468,769
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IMP RGD PMID:15105833 RGD:2313858 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Maged1 MAGE family member D1 acts_upstream_of_or_within ISO
IEA		 MGI:1929608 (PMID:17488777), (PMID:19268530)
GO_REF:0000107		 RGD
Ensembl		 PMID:17488777 PMID:19268530 GO_REF:0000107 NCBI chr  X:63,416,464...63,423,167
Ensembl chr  X:59,422,717...59,429,364 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 acts_upstream_of_or_within ISO MGI:1346862 (PMID:16458303) RGD PMID:16458303 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 acts_upstream_of_or_within ISO
IEA		 MGI:1346861 (PMID:16458303)
GO_REF:0000107		 RGD
Ensembl		 PMID:16458303 GO_REF:0000107 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mir449a microRNA 449a involved_in ISO (PMID:25487955) RGD PMID:25487955 NCBI chr 2:46,403,910...46,404,000
Ensembl chr 2:44,670,714...44,670,804 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO MGI:2447604 (PMID:14517295) RGD PMID:14517295 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 acts_upstream_of_or_within ISO (PMID:20530871) RGD PMID:20530871 NCBI chr15:33,256,912...33,284,522
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
G Ngfr nerve growth factor receptor acts_upstream_of_or_within ISO
IEA		 (PMID:10764727)
GO_REF:0000107		 RGD
Ensembl		 PMID:10764727 GO_REF:0000107 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Osm oncostatin M acts_upstream_of_or_within ISO (PMID:15012602) RGD PMID:15012602 NCBI chr14:83,327,202...83,332,073
Ensembl chr14:79,104,344...79,108,313 		JBrowse link
G Pdcd7 programmed cell death 7 acts_upstream_of_or_within ISO (PMID:10037816) RGD PMID:10037816 NCBI chr 8:74,757,768...74,772,495
Ensembl chr 8:65,862,387...65,877,333 		JBrowse link
G Pml PML nuclear body scaffold acts_upstream_of_or_within ISO
IEA		 MGI:1197015 (PMID:10684855)
GO_REF:0000107		 RGD
Ensembl		 PMID:10684855 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:18293083) RGD PMID:18293083 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prkcd protein kinase C, delta acts_upstream_of_or_within ISO
IEA		 (PMID:15731106)
GO_REF:0000107		 RGD
Ensembl		 PMID:15731106 GO_REF:0000107 NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1857937 (PMID:9778245) RGD PMID:9778245 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:1,986,225...2,025,308
Ensembl chr20:2,018,147...2,020,106 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO
IBA		 (PMID:14988002)
GO_REF:0000033		 RGD
GO_Central		 PMID:14988002 GO_REF:0000033 NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Rps3l1 ribosomal protein S3 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:71,967,699...71,968,537
Ensembl chr 3:51,559,683...51,560,524 		JBrowse link
G Sp1 Sp1 transcription factor involved_in ISO
IEA		 (PMID:18293083)
GO_REF:0000107		 RGD
Ensembl		 PMID:18293083 GO_REF:0000107 NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA		 (PMID:18758450)
GO_REF:0000107		 RGD
Ensembl		 PMID:18758450 GO_REF:0000107 NCBI chr 5:66,449,348...66,506,371
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO
IEA		 (PMID:9774969)
GO_REF:0000107		 RGD
Ensembl		 PMID:9774969 GO_REF:0000107 NCBI chr11:88,343,647...88,554,543
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO
IEA		 PR:Q9QXE4-2 (PMID:16044147)
GO_REF:0000107		 RGD
Ensembl		 PMID:16044147 GO_REF:0000107 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Tpd52l1 TPD52 like 1 involved_in ISO
IEA
IBA		 (PMID:14761963)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:14761963 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:27,991,114...28,109,767
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Traf7 TNF receptor associated factor 7 involved_in ISO
IEA		 (PMID:15001576)
GO_REF:0000107		 RGD
Ensembl		 PMID:15001576 GO_REF:0000107 NCBI chr10:14,038,117...14,056,832
Ensembl chr10:13,533,570...13,552,203 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
IEA
IBA		 (PMID:19100260)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19100260 GO_REF:0000033 GO_REF:0000107 NCBI chr20:2,008,528...2,022,383
Ensembl chr20:1,983,533...2,020,117 		JBrowse link
G Wnt5a Wnt family member 5A involved_in IEA
ISO		 GO_REF:0000107
(PMID:21857966)		 Ensembl
RGD		 PMID:21857966 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26015568), (PMID:26949185)		 UniProt
Ensembl
RGD		 PMID:26015568 PMID:26949185 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in ISO
IEA		 (PMID:22761832)
GO_REF:0000107		 RGD
Ensembl		 PMID:22761832 GO_REF:0000107 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO MGI:1913418 (PMID:22240901) RGD PMID:22240901 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IEA
IBA		 (PMID:14676213)
GO_REF:0000107
GO_REF:0000033
UniProtKB:O55033 (PMID:16835242)		 RGD
Ensembl
GO_Central		 PMID:14676213 PMID:16835242 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:109,897,723...109,958,247
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IEA
IBA		 UniProtKB:Q99M51 (PMID:16835242)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16835242 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:53,206,006...53,332,417
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21216966)		 Ensembl
RGD		 PMID:21216966 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
G Rnf183 ring finger protein 183 involved_in ISO
IEA
IBA		 (PMID:29507230)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:29507230 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:80,892,683...80,914,037
Ensembl chr 5:75,876,003...75,886,191 		JBrowse link
G Serinc3 serine incorporator 3 acts_upstream_of_or_within ISO
IEA		 (PMID:12486168)
GO_REF:0000107		 RGD
Ensembl		 PMID:12486168 GO_REF:0000107 NCBI chr 3:172,721,208...172,749,853
Ensembl chr 3:152,301,772...152,321,808 		JBrowse link
G Sirt1 sirtuin 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20955178)		 Ensembl
RGD		 PMID:20955178 GO_REF:0000107 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Spop speckle type BTB/POZ protein acts_upstream_of_or_within ISO
IEA		 MGI:102851 (PMID:20811152)
GO_REF:0000107		 RGD
Ensembl		 PMID:20811152 GO_REF:0000107 NCBI chr10:80,854,890...80,935,781
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO
IEA		 (PMID:10406457)
GO_REF:0000107		 RGD
Ensembl		 PMID:10406457 GO_REF:0000107 NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 involved_in ISO (PMID:10406457) RGD PMID:10406457 NCBI chr  X:116,914,320...116,918,504
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G App amyloid beta precursor protein involved_in ISO UniProtKB:Q9EPW9|UniProtKB:Q9QUK6 (PMID:20037584) RGD PMID:20037584 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA
ISS		 (PMID:11466612)
GO_REF:0000107
(PMID:10753917)
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:10753917 PMID:11466612 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:237,501,181...237,510,821
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bcl2l14 Bcl2-like 14 involved_in ISO (PMID:11054413) RGD PMID:11054413 NCBI chr 4:168,948,919...168,989,450
Ensembl chr 4:167,219,871...167,258,086 		JBrowse link
G Bid BH3 interacting domain death agonist involved_in ISO
IEA
IBA		 (PMID:21459798)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000104		 RGD
Ensembl
GO_Central
UniProt		 PMID:21459798 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:1889507 (PMID:16183742) RGD PMID:16183742 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:21382479)
GO_REF:0000107		 RGD
Ensembl		 PMID:21382479 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cd40lg CD40 ligand involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO
IEA
IBA		 (PMID:21525013)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21525013 GO_REF:0000033 GO_REF:0000107 NCBI chr19:34,487,491...34,547,311
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Cyld-ps1 CYLD lysine 63 deubiquitinase, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:19,999,709...20,003,695
Ensembl chr 5:15,202,251...15,205,291 		JBrowse link
G Dedd2 death effector domain containing 2 involved_in ISO
IEA		 (PMID:11741985)
GO_REF:0000107		 RGD
Ensembl		 PMID:11741985 GO_REF:0000107 NCBI chr 1:89,916,906...89,934,663
Ensembl chr 1:80,792,000...80,807,714 		JBrowse link
G Fadd Fas associated via death domain involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:21525013)
GO_REF:0000107
MGI:1336166|MGI:2154952 (PMID:22675671)		 RGD
Ensembl		 PMID:21525013 PMID:22675671 GO_REF:0000107 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Faslg Fas ligand involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G G0s2 G0/G1switch 2 involved_in ISS
IBA
ISO		 GO_REF:0000024
GO_REF:0000033
(PMID:19706769)		 UniProt
GO_Central
RGD		 PMID:19706769 GO_REF:0000024 GO_REF:0000033 NCBI chr13:107,335,036...107,335,948
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Hyal2 hyaluronidase 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19366691)
GO_REF:0000107		 RGD
Ensembl		 PMID:19366691 GO_REF:0000107 NCBI chr 8:117,121,802...117,125,494
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Itm2c integral membrane protein 2C involved_in ISO (PMID:14592447) RGD PMID:14592447 NCBI chr 9:93,993,922...94,007,737
Ensembl chr 9:86,545,921...86,559,742 		JBrowse link
G Lta lymphotoxin alpha involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,622,291...3,625,852
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Ltb lymphotoxin beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:3,632,209...3,634,054
Ensembl chr20:3,627,537...3,629,381 		JBrowse link
G Ltbr lymphotoxin beta receptor involved_in ISO (PMID:20732415) RGD PMID:20732415 NCBI chr 4:159,795,115...159,801,571
Ensembl chr 4:158,108,886...158,121,539 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO
IEA		 (PMID:19240112)
GO_REF:0000107		 RGD
Ensembl		 PMID:19240112 GO_REF:0000107 NCBI chr11:82,212,896...82,273,803
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 acts_upstream_of_or_within ISO
IEA		 (PMID:15858817)
GO_REF:0000107		 RGD
Ensembl		 PMID:15858817 GO_REF:0000107 NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pml PML nuclear body scaffold involved_in ISO
IEA		 (PMID:21803845)
GO_REF:0000107		 RGD
Ensembl		 PMID:21803845 GO_REF:0000107 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:18322138 RGD:8693423 NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:1857277 (PMID:8666928) RGD PMID:8666928 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA		 (PMID:16964285)
GO_REF:0000107		 RGD
Ensembl		 PMID:16964285 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 acts_upstream_of_or_within ISO
IEA		 MGI:5000222 (PMID:19136968)
GO_REF:0000107		 RGD
Ensembl		 PMID:19136968 GO_REF:0000107 NCBI chr 3:161,249,389...161,266,321
Ensembl chr 3:140,789,080...140,806,005 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:21525013), (PMID:22274400)
GO_REF:0000107
MGI:104798 (PMID:19498109)		 RGD
Ensembl		 PMID:19498109 PMID:21525013 PMID:22274400 GO_REF:0000107 NCBI chr17:31,044,983...31,077,167
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Runx3 RUNX family transcription factor 3 acts_upstream_of_or_within ISO MGI:2179229 (PMID:11955451) RGD PMID:11955451 NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:3045799 (PMID:14976225)
GO_REF:0000107		 RGD
Ensembl		 PMID:14976225 GO_REF:0000107 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Siglec1 sialic acid binding Ig like lectin 1 acts_upstream_of_or_within ISO MGI:3617694 (PMID:23408841) RGD PMID:23408841 NCBI chr 3:138,740,171...138,759,966
Ensembl chr 3:118,287,988...118,306,850 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P05067-PRO_0000000092 (PMID:20037584)		 Ensembl
RGD		 PMID:20037584 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tlr6 toll-like receptor 6 involved_in ISO
IEA		 UniProtKB:P05067-PRO_0000000092 (PMID:20037584)
GO_REF:0000107		 RGD
Ensembl		 PMID:20037584 GO_REF:0000107 NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685 		JBrowse link
G Tnf tumor necrosis factor involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:12131680 GO_REF:0000033, RGD:14995454 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A involved_in ISO
IBA		 (PMID:21525013)
GO_REF:0000033		 RGD
GO_Central		 PMID:21525013 GO_REF:0000033 NCBI chr10:13,211,670...13,213,666
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:20097879), (PMID:21525171), (PMID:22266862)
GO_REF:0000033
(PMID:15632112)		 RGD
GO_Central		 PMID:15632112 PMID:20097879 PMID:21525171 PMID:22266862 GO_REF:0000033 NCBI chr 2:112,136,550...112,155,903
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnfsf12 TNF superfamily member 12 involved_in ISO
IEA		 (PMID:21525013)
GO_REF:0000107		 RGD
Ensembl		 PMID:21525013 GO_REF:0000107 NCBI chr10:54,902,616...54,912,628
Ensembl chr10:54,403,870...54,413,213 		JBrowse link
G Tnfsf14 TNF superfamily member 14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:2,155,270...2,160,100
Ensembl chr 9:2,069,104...2,073,216 		JBrowse link
G Tnfsf15 TNF superfamily member 15 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:82,150,376...82,171,743
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO
IEA		 (PMID:21525013)
GO_REF:0000107		 RGD
Ensembl		 PMID:21525013 GO_REF:0000107 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Wdr35 WD repeat domain 35 IMP RGD PMID:20193664 RGD:11553917 NCBI chr 6:37,490,557...37,550,391
Ensembl chr 6:31,771,360...31,831,029 		JBrowse link
G Wwox WW domain-containing oxidoreductase involved_in ISO (PMID:19366691) RGD PMID:19366691 NCBI chr19:59,338,402...60,269,323
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO
IEA		 MGI:2677796 (PMID:22411810)
GO_REF:0000107		 RGD
Ensembl		 PMID:22411810 GO_REF:0000107 NCBI chr18:27,002,330...27,135,009
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr 7:9,174,903...9,183,272
Ensembl chr 7:8,524,183...8,532,558 		JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO
IEA		 (PMID:20125124)
GO_REF:0000107		 RGD
Ensembl		 PMID:20125124 GO_REF:0000107 NCBI chr 4:117,114,631...117,117,793
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
IEA
ISS		 (PMID:8267637)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:8267637 GO_REF:0000024 GO_REF:0000107 NCBI chr17:53,787,159...53,810,942
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (PMID:16020505) RGD PMID:16020505 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Nf1 neurofibromin 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857478 (PMID:15039234)
GO_REF:0000107		 RGD
Ensembl		 PMID:15039234 GO_REF:0000107 NCBI chr10:64,803,986...65,037,086
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha acts_upstream_of_or_within ISO
IEA		 (PMID:12115603)
GO_REF:0000107		 RGD
Ensembl		 PMID:12115603 GO_REF:0000107 NCBI chr 1:210,914,576...210,918,193
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO (PMID:12944463) RGD PMID:12944463 NCBI chr 1:69,213,198...69,232,441
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta involved_in ISO
IEA		 (PMID:21172653)
GO_REF:0000107		 RGD
Ensembl		 PMID:21172653 GO_REF:0000107 NCBI chr 8:60,092,540...60,125,512
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:152,998,344...153,040,556
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within ISO
IEA		 MGI:3706175 (PMID:17088259)
GO_REF:0000107		 RGD
Ensembl		 PMID:17088259 GO_REF:0000107 NCBI chr  X:15,349,498...15,420,389
Ensembl chr  X:12,566,645...12,747,882 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of_or_within ISO
IEA		 (PMID:8206089)
GO_REF:0000107		 RGD
Ensembl		 PMID:8206089 GO_REF:0000107 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr20:29,240,639...29,307,270
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (PMID:19366691) RGD PMID:19366691 NCBI chr19:59,338,402...60,269,323
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1b bone morphogenetic protein receptor type 1B acts_upstream_of_or_within ISO
IEA		 MGI:1927616|MGI:95484 (PMID:18363966)
GO_REF:0000107		 RGD
Ensembl		 PMID:18363966 GO_REF:0000107 NCBI chr 2:233,211,525...233,544,344
Ensembl chr 2:230,541,558...230,871,368 		JBrowse link
G Faf1 Fas associated factor 1 acts_upstream_of_or_within ISO
IEA		 (PMID:8524870)
GO_REF:0000107		 RGD
Ensembl		 PMID:8524870 GO_REF:0000107 NCBI chr 5:129,654,677...130,018,604
Ensembl chr 5:124,426,062...124,789,977 		JBrowse link
G Mal mal, T-cell differentiation protein acts_upstream_of_or_within ISO
IEA		 (PMID:12776198)
GO_REF:0000107		 RGD
Ensembl		 PMID:12776198 GO_REF:0000107 NCBI chr 3:135,317,664...135,341,423
Ensembl chr 3:114,864,378...114,888,136 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 acts_upstream_of_or_within ISO (PMID:10588860) RGD PMID:10588860 NCBI chr13:87,190,189...87,199,811
Ensembl chr13:84,654,870...84,667,499 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15705586) RGD PMID:15705586 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Psen2 presenilin 2 acts_upstream_of_or_within ISO (PMID:8940094) RGD PMID:8940094 NCBI chr13:94,499,451...94,528,419
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO
IEA		 (PMID:9391078)
GO_REF:0000107		 RGD
Ensembl		 PMID:9391078 GO_REF:0000107 NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO
IEA		 MGI:2387096 (PMID:10811619)
GO_REF:0000107		 RGD
Ensembl		 PMID:10811619 GO_REF:0000107 NCBI chr 2:114,175,534...114,203,663
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Stk3 serine/threonine kinase 3 acts_upstream_of_or_within ISO MGI:104798|MGI:1928487|MGI:1929004 (PMID:20080598) RGD PMID:20080598 NCBI chr 7:67,938,341...68,208,472
Ensembl chr 7:66,052,345...66,323,233 		JBrowse link
G Stk4 serine/threonine kinase 4 acts_upstream_of_or_within ISO
IEA		 MGI:104798|MGI:1928487 (PMID:20080598)
GO_REF:0000107		 RGD
Ensembl		 PMID:20080598 GO_REF:0000107 NCBI chr 3:173,165,238...173,247,135
Ensembl chr 3:152,745,681...152,827,744 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO
IEA		 (PMID:18726995)
GO_REF:0000107		 RGD
Ensembl		 PMID:18726995 GO_REF:0000107 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Trps1 transcriptional repressor GATA binding 1 acts_upstream_of_or_within ISO MGI:107191|MGI:95484 (PMID:18363966) RGD PMID:18363966 NCBI chr 7:83,806,121...84,032,609
Ensembl chr 7:81,921,601...82,141,905 		JBrowse link
G Zswim2 zinc finger, SWIM-type containing 2 acts_upstream_of_or_within ISO
IEA		 (PMID:16522193)
GO_REF:0000107		 RGD
Ensembl		 PMID:16522193 GO_REF:0000107 NCBI chr 3:89,401,887...89,422,308
Ensembl chr 3:68,995,027...69,015,411 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IDA MMO:0000679 RGD PMID:23729662 RGD:329403056 NCBI chr13:80,280,595...80,366,939
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
MGI:2158306 (PMID:14502238)
(PMID:14963330), (PMID:21199865), (PMID:21262771)		 UniProt
Ensembl
RGD		 PMID:14502238 PMID:14963330 PMID:21199865 PMID:21262771 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in IMP
ISO
ISS		 PMID:27031958
(PMID:17289999), (PMID:27031958)
GO_REF:0000024		 RGD
UniProt		 PMID:17289999 PMID:27031958 PMID:27031958 GO_REF:0000024, RGD:14390051 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcap31 B-cell receptor-associated protein 31 involved_in ISO
IEA		 (PMID:21183955)
GO_REF:0000107		 RGD
Ensembl		 PMID:21183955 GO_REF:0000107 NCBI chr  X:156,548,911...156,581,002
Ensembl chr  X:151,397,576...151,428,506 		JBrowse link
G Bcl2l11 Bcl2-like 11 involved_in ISO (PMID:21671007) RGD PMID:21671007 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 involved_in ISO
IEA		 (PMID:17938203)
GO_REF:0000107		 RGD
Ensembl		 PMID:17938203 GO_REF:0000107 NCBI chr 1:16,904,572...16,937,106
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Becn1 beclin 1 involved_in IMP
IEA
ISO
ISS		 PMID:27031958
GO_REF:0000107
(PMID:27031958)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:27031958 PMID:27031958 GO_REF:0000024 GO_REF:0000107, RGD:14390051 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bid BH3 interacting domain death agonist involved_in ISO
IEA
IBA		 (PMID:21262771)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000104		 RGD
Ensembl
GO_Central
UniProt		 PMID:21262771 GO_REF:0000033 GO_REF:0000104 GO_REF:0000107 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:23429263)		 UniProt
Ensembl
RGD		 PMID:23429263 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase acts_upstream_of_or_within ISO MGI:3793294 (PMID:17938250) RGD PMID:17938250 NCBI chr 3:135,473,525...135,504,921
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G Cav1 caveolin 1 involved_in ISO
IEA		 (PMID:21382479)
GO_REF:0000107		 RGD
Ensembl		 PMID:21382479 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Clu clusterin involved_in ISS
ISO		 GO_REF:0000024
(PMID:21567405)		 UniProt
RGD		 PMID:21567405 GO_REF:0000024 NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cyct cytochrome c, testis acts_upstream_of_or_within ISO
IEA		 (PMID:16757556)
GO_REF:0000107		 RGD
Ensembl		 PMID:16757556 GO_REF:0000107 NCBI chr 3:81,697,333...81,704,401
Ensembl chr 3:60,913,562...61,297,158 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27031958)		 UniProt
Ensembl
RGD		 PMID:27031958 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein acts_upstream_of_or_within ISO
IEA		 (PMID:17981155)
GO_REF:0000107		 RGD
Ensembl		 PMID:17981155 GO_REF:0000107 NCBI chr 8:44,683,138...44,699,502
Ensembl chr 8:36,494,289...36,510,571 		JBrowse link
G Fis1 fission, mitochondrial 1 involved_in ISO
IEA		 (PMID:21183955)
GO_REF:0000107		 RGD
Ensembl		 PMID:21183955 GO_REF:0000107 NCBI chr12:25,345,239...25,360,135
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Flcn folliculin acts_upstream_of_or_within ISO
IEA		 MGI:4348628 (PMID:21258407)
GO_REF:0000107		 RGD
Ensembl		 PMID:21258407 GO_REF:0000107 NCBI chr10:45,088,164...45,107,581
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Gsdme gasdermin E involved_in ISO
IEA		 (PMID:21522185)
GO_REF:0000107		 RGD
Ensembl		 PMID:21522185 GO_REF:0000107 NCBI chr 4:80,590,344...80,651,943
Ensembl chr 4:79,257,804...79,320,806 		JBrowse link
G Il19 interleukin 19 acts_upstream_of_or_within ISO MGI:3605069 (PMID:23468852) RGD PMID:23468852 NCBI chr13:44,949,989...44,958,714
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Il20ra interleukin 20 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1890472 (PMID:23468852) RGD PMID:23468852 NCBI chr 1:16,243,683...16,313,229
Ensembl chr 1:14,451,228...14,493,602 		JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:16116473) RGD PMID:16116473 NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:141,888,326...141,903,794 		JBrowse link
G Mir16-2 microRNA 16-2 involved_in ISO RNAcentral:URS00003D1AE3_9606 (PMID:16166262) RGD PMID:16166262 NCBI chr 2:155,555,327...155,555,421
Ensembl chr 2:153,245,349...153,245,443 		JBrowse link
G Mir27b microRNA 27b acts_upstream_of_or_within ISO UniProtKB:P01375 (PMID:31124343) RGD PMID:31124343 NCBI chr17:1,819,147...1,819,243
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mtfr2 mitochondrial fission regulator 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:16,942,814...16,958,218
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 involved_in ISO (PMID:20012548) RGD PMID:20012548 NCBI chr10:100,902,165...100,919,265
Ensembl chr10:100,403,069...100,420,598 		JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO
IEA		 (PMID:17486276)
GO_REF:0000107		 RGD
Ensembl		 PMID:17486276 GO_REF:0000107 NCBI chr15:50,883,661...50,886,253
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
IEA
ISS
IMP		 (PMID:27031958)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:27031958 PMID:27031958 GO_REF:0000024 GO_REF:0000107, RGD:14390051 NCBI chr 1:190,643,866...190,645,901
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IMP RGD PMID:10349840 RGD:9835366 NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Plagl2 PLAG1 like zinc finger 2 acts_upstream_of_or_within ISO
IEA		 (PMID:11832486)
GO_REF:0000107		 RGD
Ensembl		 PMID:11832486 GO_REF:0000107 NCBI chr 3:162,155,554...162,168,748
Ensembl chr 3:141,695,322...141,708,503 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:21454712) RGD PMID:21454712 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Prkra protein activator of interferon induced protein kinase EIF2AK2 acts_upstream_of_or_within ISO
IEA		 (PMID:12181197)
GO_REF:0000107		 RGD
Ensembl		 PMID:12181197 GO_REF:0000107 NCBI chr 3:81,982,669...82,002,028
Ensembl chr 3:61,575,447...61,594,347 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 acts_upstream_of_or_within ISO (PMID:10490590) RGD PMID:10490590 NCBI chr15:33,253,071...33,262,025
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G S100a8 S100 calcium binding protein A8 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19935772)		 UniProt
Ensembl
RGD		 PMID:19935772 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:19935772)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:19935772 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Septin4 septin 4 involved_in ISO (PMID:21185211) RGD PMID:21185211 NCBI chr10:72,863,969...72,888,018
Ensembl chr10:72,366,873...72,390,768 		JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 involved_in ISO
IEA		 (PMID:21185211)
GO_REF:0000107		 RGD
Ensembl		 PMID:21185211 GO_REF:0000107 NCBI chr19:36,552,165...36,575,773
Ensembl chr19:20,378,439...20,403,808 		JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO
IEA
IBA		 (PMID:21262771), (PMID:24709986)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21262771 PMID:24709986 GO_REF:0000033 GO_REF:0000107 NCBI chr12:26,544,059...26,576,365
Ensembl chr12:20,907,435...20,939,752 		JBrowse link
G Taf6 TATA-box binding protein associated factor 6 involved_in ISO (PMID:20096117) RGD PMID:20096117 NCBI chr12:22,169,570...22,178,031
Ensembl chr12:17,055,873...17,064,247 		JBrowse link
G Tp53 tumor protein p53 involved_in ISS
IEA
ISO
IMP		 GO_REF:0000024
GO_REF:0000107
(PMID:14963330), (PMID:27031958)		 UniProt
Ensembl
RGD		 PMID:14963330 PMID:27031958 PMID:27031958 GO_REF:0000024 GO_REF:0000107, RGD:14390051 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif5a eukaryotic translation initiation factor 5A involved_in ISO (PMID:15371445) RGD PMID:15371445 NCBI chr10:55,138,821...55,143,272
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G Mir186 microRNA 186 acts_upstream_of ISO (PMID:27714074) RGD PMID:27714074 NCBI chr 2:249,241,650...249,241,735
Ensembl chr 2:246,582,806...246,582,891 		JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (PMID:15705871) RGD PMID:15705871 NCBI chr14:77,185,802...77,189,735
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in ISO (PMID:10962037) RGD PMID:10962037 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Rps7 ribosomal protein S7 involved_in ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:50,994,581...50,999,447
Ensembl chr 6:45,223,980...45,271,145
Ensembl chr 5:45,223,980...45,271,145 		JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 involved_in ISO (PMID:24523556) RGD PMID:24523556 NCBI chr 2:236,411,194...236,445,225
Ensembl chr 2:233,750,838...233,784,784 		JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:17805299) RGD PMID:17805299 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:108,169,980...108,269,822 		JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO
IEA		 (PMID:17571083)
GO_REF:0000107		 RGD
Ensembl		 PMID:17571083 GO_REF:0000107 NCBI chr10:47,746,923...47,748,628
Ensembl chr10:47,245,637...47,249,333 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbh1 F-box DNA helicase 1 acts_upstream_of_or_within ISO (PMID:23361013) RGD PMID:23361013 NCBI chr17:71,659,351...71,697,431
Ensembl chr17:66,749,534...66,787,590 		JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (PMID:26219591) RGD PMID:26219591 NCBI chr 3:97,286,388...97,306,028
Ensembl chr 3:76,830,413...76,850,189 		JBrowse link
G Nacc2 NACC family member 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:22926524)		 Ensembl
RGD		 PMID:22926524 GO_REF:0000107 NCBI chr 3:29,278,077...29,345,098
Ensembl chr 3:8,883,065...8,946,660 		JBrowse link
G Pias4 protein inhibitor of activated STAT, 4 acts_upstream_of_or_within ISO
IEA		 (PMID:16816390)
GO_REF:0000107		 RGD
Ensembl		 PMID:16816390 GO_REF:0000107 NCBI chr 7:9,197,032...9,210,557
Ensembl chr 7:8,546,312...8,559,808 		JBrowse link
G Plscr1 phospholipid scramblase 1 acts_upstream_of_or_within ISO
IEA		 (PMID:12509439)
GO_REF:0000107		 RGD
Ensembl		 PMID:12509439 GO_REF:0000107 NCBI chr 8:101,662,512...101,684,474
Ensembl chr 8:92,784,356...92,804,692 		JBrowse link
G Rad9a RAD9 checkpoint clamp component A acts_upstream_of_or_within ISO
IEA		 MGI:2442925 (PMID:15983387)
GO_REF:0000107		 RGD
Ensembl		 PMID:15983387 GO_REF:0000107 NCBI chr 1:210,917,970...210,983,038
Ensembl chr 1:201,487,136...201,553,608 		JBrowse link
G Rps3 ribosomal protein S3 involved_in ISO (PMID:22510408) RGD PMID:22510408 NCBI chr 1:163,190,476...163,195,885
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Skil SKI-like proto-oncogene acts_upstream_of_or_within ISO
IEA		 MGI:2387096 (PMID:10811619)
GO_REF:0000107		 RGD
Ensembl		 PMID:10811619 GO_REF:0000107 NCBI chr 2:114,175,534...114,203,663
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Knl1 kinetochore scaffold 1 acts_upstream_of_or_within ISO (PMID:31197172) RGD PMID:31197172 NCBI chr 3:126,483,498...126,545,774
Ensembl chr 3:106,029,661...106,091,915 		JBrowse link
G Rpl26 ribosomal protein L26 involved_in ISO (PMID:16213212) RGD PMID:16213212 NCBI chr10:54,109,692...54,112,822
Ensembl chr10:53,610,421...53,613,966 		JBrowse link
G Steap3 STEAP3 metalloreductase acts_upstream_of_or_within ISO MGI:4398911 (PMID:18617898) RGD PMID:18617898 NCBI chr13:33,904,710...33,950,100
Ensembl chr13:31,351,954...31,396,519 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within ISO
IEA		 MGI:2442925|MGI:98834 (PMID:15983387)
GO_REF:0000107		 RGD
Ensembl		 PMID:15983387 GO_REF:0000107 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISO (PMID:21716255) RGD PMID:21716255 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 acts_upstream_of_or_within ISO (PMID:19096392) RGD PMID:19096392 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:26949185)		 UniProt
Ensembl
RGD		 PMID:26949185 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Chchd10 coiled-coil-helix-coiled-coil-helix domain containing 10 involved_in ISO (PMID:26666268), (PMID:30092269) RGD PMID:26666268 PMID:30092269 NCBI chr20:12,725,274...12,730,295
Ensembl chr20:12,725,842...12,732,763 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISS
ISO		 GO_REF:0000024
(PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:16543145)		 UniProt
RGD		 PMID:16543145 GO_REF:0000024 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO
IEA		 UniProtKB:Q9HD36 (PMID:19255499)
GO_REF:0000107		 RGD
Ensembl		 PMID:19255499 GO_REF:0000107 NCBI chr12:38,251,085...38,279,756
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21370995) RGD PMID:21370995 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor involved_in ISO (PMID:15034012) RGD PMID:15034012 NCBI chr 6:137,526,416...137,530,790
Ensembl chr 6:131,705,323...131,709,690 		JBrowse link
G Zfp13 zinc finger protein 13 involved_in ISO
IEA		 (PMID:22306510)
GO_REF:0000107		 RGD
Ensembl		 PMID:22306510 GO_REF:0000107 NCBI chr10:13,119,707...13,128,284
Ensembl chr10:12,615,190...12,623,615 		JBrowse link
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nox1 NADPH oxidase 1 acts_upstream_of_or_within ISO
IEA		 MGI:3616995 (PMID:19661248)
GO_REF:0000107		 RGD
Ensembl		 PMID:19661248 GO_REF:0000107 NCBI chr  X:101,572,338...101,625,571
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:22555455) RGD PMID:22555455 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Sfpq splicing factor proline and glutamine rich involved_in ISO
IEA		 (PMID:15790595)
GO_REF:0000107		 RGD
Ensembl		 PMID:15790595 GO_REF:0000107 NCBI chr 5:144,621,678...144,637,930
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISO
IEA		 (PMID:12551919)
GO_REF:0000107		 RGD
Ensembl		 PMID:12551919 GO_REF:0000107 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Vnn1 vanin 1 involved_in ISO
IEA		 (PMID:15282320)
GO_REF:0000107		 RGD
Ensembl		 PMID:15282320 GO_REF:0000107 NCBI chr 1:23,356,324...23,366,629
Ensembl chr 1:21,537,094...21,547,395 		JBrowse link
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:28386847 RGD:329337357 NCBI chr13:80,280,595...80,366,939
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO
IEA		 (PMID:23858059)
GO_REF:0000107		 RGD
Ensembl		 PMID:23858059 GO_REF:0000107 NCBI chr 2:172,447,738...172,609,591
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO UniProtKB:Q9WVS6 (PMID:23858059) RGD PMID:23858059 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IMP RGD PMID:27614125 RGD:329961568 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Ralbp1 ralA binding protein 1 IMP RGD PMID:23788031 RGD:12904719 NCBI chr 9:112,903,289...112,940,093
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
positive regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death involved_in ISO (PMID:17289999) RGD PMID:17289999 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 IMP RGD PMID:12485416 RGD:2317097 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in ISO
IEA
ISS		 (PMID:14963330), (PMID:21262771)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:14963330 PMID:21262771 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO
IEA
IBA		 UniProtKB:P70444 (PMID:21041309)
GO_REF:0000002
GO_REF:0000033		 RGD
InterPro
GO_Central		 PMID:21041309 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2l11 Bcl2-like 11 involved_in ISO UniProtKB:P70444 (PMID:17289999), (PMID:21041309) RGD PMID:17289999 PMID:21041309 NCBI chr 3:135,820,042...135,857,330
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bid BH3 interacting domain death agonist involved_in ISS
IBA
IMP
ISO
IEA		 GO_REF:0000024
GO_REF:0000033
UniProtKB:O08734|UniProtKB:P70444 (PMID:10950869), (PMID:21041309)
GO_REF:0000107
(PMID:32029622)
UniProtKB:P70444 (PMID:17289999), (PMID:21041309), (PMID:21262771)		 UniProt
GO_Central
RGD
Ensembl		 PMID:10950869 PMID:17289999 PMID:21041309 PMID:21262771 PMID:32029622 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:408345233 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bik BCL2-interacting killer involved_in ISO (PMID:21041309) RGD PMID:21041309 NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G Bmf Bcl2 modifying factor involved_in ISO UniProtKB:P70444 (PMID:21041309) RGD PMID:21041309 NCBI chr 3:125,953,466...125,974,087
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Bnip3 BCL2 interacting protein 3 involved_in ISO
IEA		 (PMID:20436456)
GO_REF:0000107		 RGD
Ensembl		 PMID:20436456 GO_REF:0000107 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Fam162a family with sequence similarity 162, member A involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:15082785)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:15082785 GO_REF:0000024 GO_REF:0000033 NCBI chr11:78,186,260...78,215,186
Ensembl chr11:64,680,323...64,711,239 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr12:20,331,073...20,336,527
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Hrk harakiri, BCL2 interacting protein involved_in ISO
IEA		 (PMID:21041309)
GO_REF:0000107		 RGD
Ensembl		 PMID:21041309 GO_REF:0000107 NCBI chr12:44,048,402...44,070,561 JBrowse link
G LOC120095320 protein FAM162A-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:36,888,062...36,899,122
Ensembl chr10:36,390,113...36,390,613 		JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:18852119)		 UniProt
Ensembl
GO_Central
RGD		 PMID:18852119 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:185,484,791...185,493,961
Ensembl chr 2:182,795,790...182,797,199 		JBrowse link
G Mmp9 matrix metallopeptidase 9 involved_in ISO
IEA		 (PMID:22984561)
GO_REF:0000107		 RGD
Ensembl		 PMID:22984561 GO_REF:0000107 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Moap1 modulator of apoptosis 1 involved_in ISO (PMID:16199525) RGD PMID:16199525 NCBI chr 6:127,647,389...127,649,324
Ensembl chr 6:121,882,366...121,898,643
Ensembl chr17:121,882,366...121,898,643 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO
IEA		 (PMID:19880420)
GO_REF:0000107		 RGD
Ensembl		 PMID:19880420 GO_REF:0000107 NCBI chr 5:155,813,838...155,825,950
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Pla2g6 phospholipase A2 group VI IDA RGD PMID:18936091 RGD:6482750 NCBI chr 7:112,731,803...112,771,978
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in ISO
IEA		 (PMID:22984561)
GO_REF:0000107		 RGD
Ensembl		 PMID:22984561 GO_REF:0000107 NCBI chr 1:89,181,363...89,196,308
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14500711), (PMID:14699081), (PMID:15705586), (PMID:17289999) RGD PMID:14500711 PMID:14699081 PMID:15705586 PMID:17289999 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA		 (PMID:14730312)
GO_REF:0000107		 RGD
Ensembl		 PMID:14730312 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in ISO (PMID:22266862) RGD PMID:22266862 NCBI chr 2:112,136,550...112,155,903
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA		 (PMID:14963330)
GO_REF:0000107		 RGD
Ensembl		 PMID:14963330 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Wdr35 WD repeat domain 35 IMP RGD PMID:23289926 RGD:11553920 NCBI chr 6:37,490,557...37,550,391
Ensembl chr 6:31,771,360...31,831,029 		JBrowse link
positive regulation of TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 involved_in ISO
IEA		 (PMID:24939851)
GO_REF:0000107		 RGD
Ensembl		 PMID:24939851 GO_REF:0000107 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
regulation of apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp8 caspase 8 acts_upstream_of_or_within ISO MGI:103223 (PMID:15456877) RGD PMID:15456877 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Pmp22 peripheral myelin protein 22 acts_upstream_of_or_within ISO MGI:1856217 (PMID:23847051) RGD PMID:23847051 NCBI chr10:48,294,932...48,324,941
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO		 GO_REF:0000024
(PMID:23180369)		 UniProt
RGD		 PMID:23180369 GO_REF:0000024 NCBI chr14:85,491,223...85,496,884
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,361,379...21,362,147
Ensembl chr14:21,006,538...21,007,310 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor acts_upstream_of_or_within ISO
IEA		 MGI:1261423 (PMID:15456877)
GO_REF:0000107		 RGD
Ensembl		 PMID:15456877 GO_REF:0000107 NCBI chr 4:148,328,099...148,334,992
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO
IEA		 (PMID:23000344)
GO_REF:0000107		 RGD
Ensembl		 PMID:23000344 GO_REF:0000107 NCBI chr 4:104,363,838...104,425,271
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 involved_in ISO
IEA		 (PMID:24370996)
GO_REF:0000107		 RGD
Ensembl		 PMID:24370996 GO_REF:0000107 NCBI chr12:40,750,177...40,756,607
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in ISO (PMID:15147274) RGD PMID:15147274 NCBI chr19:10,604,360...10,624,168
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein involved_in ISO ComplexPortal:CPX-1134 (PMID:23921129) RGD PMID:23921129 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Fcgr2b Fc gamma receptor 2B involved_in IMP
ISO		 PMID:23921129
(PMID:23921129)		 RGD PMID:23921129 PMID:23921129 RGD:12910988 NCBI chr13:85,725,897...85,740,517
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
regulation of extrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl5 acyl-CoA synthetase long-chain family member 5 involved_in ISO (PMID:17681178) RGD PMID:17681178 NCBI chr 1:264,294,851...264,341,943
Ensembl chr 1:254,292,521...254,336,607 		JBrowse link
G Dbh dopamine beta-hydroxylase acts_upstream_of_or_within ISO
IEA		 MGI:1857556 (PMID:15849236)
GO_REF:0000107		 RGD
Ensembl		 PMID:15849236 GO_REF:0000107 NCBI chr 3:30,886,313...30,903,313
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein involved_in ISO
IEA		 (PMID:19446321)
GO_REF:0000107		 RGD
Ensembl		 PMID:19446321 GO_REF:0000107 NCBI chr 7:88,404,745...88,574,065
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Madd MAP-kinase activating death domain involved_in ISO (PMID:11577081) RGD PMID:11577081 NCBI chr 3:97,570,141...97,613,688
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO (PMID:7743522) RGD PMID:7743522 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Traf1 TNF receptor-associated factor 1 involved_in ISO
IEA		 (PMID:10692572)
GO_REF:0000107		 RGD
Ensembl		 PMID:10692572 GO_REF:0000107 NCBI chr 3:38,607,707...38,639,641
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO
IEA		 MGI:2176216|MGI:2181474 (PMID:16207751), (PMID:18191119)
GO_REF:0000107		 RGD
Ensembl		 PMID:16207751 PMID:18191119 GO_REF:0000107 NCBI chr16:73,194,631...73,249,855
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
regulation of extrinsic apoptotic signaling pathway via death domain receptors term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fem1b fem-1 homolog B involved_in ISO
IEA		 (PMID:10542291)
GO_REF:0000107		 RGD
Ensembl		 PMID:10542291 GO_REF:0000107 NCBI chr 8:72,160,722...72,173,996
Ensembl chr 8:63,265,301...63,278,577 		JBrowse link
G Lgals3 galectin 3 involved_in ISO
IEA		 (PMID:8692888)
GO_REF:0000107		 RGD
Ensembl		 PMID:8692888 GO_REF:0000107 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Madd MAP-kinase activating death domain involved_in ISS
ISO		 GO_REF:0000024
(PMID:9115275)		 UniProt
RGD		 PMID:9115275 GO_REF:0000024 NCBI chr 3:97,570,141...97,613,688
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
G Sp100 SP100 nuclear antigen involved_in ISO (PMID:17245429) RGD PMID:17245429 NCBI chr 9:93,758,975...93,825,068
Ensembl chr 9:86,311,032...86,377,034 		JBrowse link
G Stx4 syntaxin 4 involved_in ISO (PMID:20956541) RGD PMID:20956541 NCBI chr 1:191,880,549...191,890,333
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
G Tmc8 transmembrane channel-like 8 involved_in ISO
IEA		 (PMID:23429285)
GO_REF:0000107		 RGD
Ensembl		 PMID:23429285 GO_REF:0000107 NCBI chr10:103,498,505...103,509,496
Ensembl chr10:102,998,402...103,010,590 		JBrowse link
regulation of intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyld CYLD lysine 63 deubiquitinase involved_in ISO
IEA
IBA		 (PMID:21525013)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21525013 GO_REF:0000033 GO_REF:0000107 NCBI chr19:34,487,491...34,547,311
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Cyld-ps1 CYLD lysine 63 deubiquitinase, pseudogene 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:19,999,709...20,003,695
Ensembl chr 5:15,202,251...15,205,291 		JBrowse link
G Dapk2 death-associated protein kinase 2 involved_in ISO
IEA		 (PMID:10376525)
GO_REF:0000107		 RGD
Ensembl		 PMID:10376525 GO_REF:0000107 NCBI chr 8:75,601,621...75,720,619
Ensembl chr 8:66,706,609...66,825,567 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 involved_in ISO
IEA		 UniProtKB:Q9Y6J8 (PMID:24709986)
GO_REF:0000107		 RGD
Ensembl		 PMID:24709986 GO_REF:0000107 NCBI chr 3:97,345,752...97,355,396
Ensembl chr 3:76,889,922...76,899,427 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO
IEA		 (PMID:14730312)
GO_REF:0000107		 RGD
Ensembl		 PMID:14730312 GO_REF:0000107 NCBI chr 1:192,032,124...192,033,419
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Styxl1 serine/threonine/tyrosine interacting-like 1 involved_in ISO
IEA		 UniProtKB:Q8WUK0 (PMID:24709986)
GO_REF:0000107		 RGD
Ensembl		 PMID:24709986 GO_REF:0000107 NCBI chr12:26,544,059...26,576,365
Ensembl chr12:20,907,435...20,939,752 		JBrowse link
regulation of intrinsic apoptotic signaling pathway by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 acts_upstream_of_or_within ISO (PMID:18302940) RGD PMID:18302940 NCBI chr 1:250,796,419...250,805,867
Ensembl chr 1:240,847,072...240,856,566 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO
IEA		 (PMID:17571083)
GO_REF:0000107		 RGD
Ensembl		 PMID:17571083 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpk heterogeneous nuclear ribonucleoprotein K acts_upstream_of_or_within ISO
IEA		 (PMID:20673990)
GO_REF:0000107		 RGD
Ensembl		 PMID:20673990 GO_REF:0000107 NCBI chr17:6,269,302...6,280,429
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G LOC100359916 heterogeneous nuclear ribonucleoprotein K-like acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:63,464,019...63,465,907
Ensembl chr 5:58,668,327...58,670,220 		JBrowse link
regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100360522 ribosomal protein P1-like acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr17:8,436,843...8,437,954
Ensembl chr17:8,431,465...8,435,348
Ensembl chr 8:8,431,465...8,435,348 		JBrowse link
G Rplp1 ribosomal protein lateral stalk subunit P1 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:71,289,539...71,290,872
Ensembl chr 8:62,393,177...62,395,339 		JBrowse link
G Tifab TIFA inhibitor acts_upstream_of_or_within ISO (PMID:32101751) RGD PMID:32101751 NCBI chr17:8,438,622...8,441,750
Ensembl chr17:8,431,635...8,436,592 		JBrowse link
G Usp15 ubiquitin specific peptidase 15 acts_upstream_of_or_within ISO
IEA		 (PMID:32101751)
GO_REF:0000107		 RGD
Ensembl		 PMID:32101751 GO_REF:0000107 NCBI chr 7:60,643,611...60,805,137
Ensembl chr 7:58,756,872...58,848,721 		JBrowse link
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO
IEA		 (PMID:18591963)
GO_REF:0000107		 RGD
Ensembl		 PMID:18591963 GO_REF:0000107 NCBI chr 5:155,936,112...155,945,163
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Tmem102 transmembrane protein 102 involved_in ISO
IEA		 (PMID:17828305)
GO_REF:0000107		 RGD
Ensembl		 PMID:17828305 GO_REF:0000107 NCBI chr10:55,022,625...55,025,676
Ensembl chr10:54,523,585...54,525,990 		JBrowse link
regulation of oxidative stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P4hb prolyl 4-hydroxylase subunit beta involved_in ISO
IEA		 (PMID:12095988)
GO_REF:0000107		 RGD
Ensembl		 PMID:12095988 GO_REF:0000107 NCBI chr10:106,335,300...106,346,911
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Ubqln1 ubiquilin 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12095988)
GO_REF:0000107		 HGNC
RGD
Ensembl		 PMID:12095988 GO_REF:0000024 GO_REF:0000107 NCBI chr17:6,438,456...6,482,498
Ensembl chr17:6,439,002...6,477,090 		JBrowse link
regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:15983381) RGD PMID:15983381 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP RGD PMID:17347665 RGD:10414071 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Prodh proline dehydrogenase involved_in ISO (PMID:23743200) RGD PMID:23743200 NCBI chr11:96,414,275...96,431,604
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:30684126) RGD PMID:30684126 NCBI chr 9:20,145,215...20,151,797
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plscr3 phospholipid scramblase 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:14573790), (PMID:18358005)		 UniProt
Ensembl
RGD		 PMID:14573790 PMID:18358005 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,064,349...55,070,120
Ensembl chr10:54,566,873...54,578,709 		JBrowse link
release of cytochrome c from mitochondria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856098 (PMID:11311799) RGD PMID:11311799 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3029528 (PMID:12431371)		 GO_Central
RGD		 PMID:12431371 GO_REF:0000033 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 involved_in IMP
IEA
ISO
IBA		 positive regulation
GO_REF:0000107
(PMID:10950869)
GO_REF:0000033
UniProtKB:O08734 (PMID:16199525), (PMID:21041309), (PMID:9843949)		 Ensembl
RGD
GO_Central		 PMID:9843949 PMID:10950869 PMID:16199525 PMID:21041309 PMID:18252800 GO_REF:0000033 GO_REF:0000107, RGD:2313987 NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IDA
IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
MGI:108093|MGI:98834 (PMID:12925707), (PMID:14614769), (PMID:14623868), (PMID:14963330), (PMID:17052454), (PMID:9560217)
(PMID:16199525), (PMID:17052454), (PMID:25609812), (PMID:9843949)		 Ensembl
GO_Central
RGD		 PMID:9560217 PMID:9843949 PMID:12925707 PMID:14614769 PMID:14623868 More... GO_REF:0000033 GO_REF:0000107, RGD:14394498 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 involved_in ISO
IBA		 (PMID:11463392)
GO_REF:0000033		 RGD
GO_Central		 PMID:11463392 GO_REF:0000033 NCBI chr 1:86,141,450...86,150,666
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISS
ISO
IBA		 PMID:9843949
(PMID:9843949)
GO_REF:0000033		 RGD
GO_Central		 PMID:9843949 PMID:9843949 GO_REF:0000033, RGD:8554139 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:9843949)
GO_REF:0000033
MGI:99702 (PMID:17052454)		 RGD
GO_Central		 PMID:9843949 PMID:17052454 GO_REF:0000033 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl2l10 Bcl2-like 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:84,987,833...84,993,878
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Bcl2l2 Bcl2-like 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:32,326,686...32,337,834
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Bid BH3 interacting domain death agonist involved_in
acts_upstream_of_or_within		 IDA
ISO
IEA		 (PMID:18084238)
MGI:2158671 (PMID:11369777)
GO_REF:0000107
(PMID:17052454)		 RGD
Ensembl		 PMID:11369777 PMID:17052454 PMID:18084238 PMID:18252800 GO_REF:0000107, RGD:2313987 NCBI chr 4:155,785,366...155,808,775
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO
IEA
IBA		 (PMID:27505430)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:27505430 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Cck cholecystokinin IDA RGD PMID:11964411 RGD:625521 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase involved_in ISO
IEA		 (PMID:16765912)
GO_REF:0000107		 RGD
Ensembl		 PMID:16765912 GO_REF:0000107 NCBI chr 4:85,453,387...85,459,597
Ensembl chr 4:84,123,118...84,129,277 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IMP induces release following removal of NGF from sympathetic neurons RGD PMID:11301023 RGD:2290592 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:15504737 RGD:2298783 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2678372 (PMID:12952892)
GO_REF:0000002
(PMID:14699081)		 RGD
InterPro		 PMID:12952892 PMID:14699081 GO_REF:0000002 NCBI chr18:62,255,970...62,262,384
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Sfn stratifin involved_in ISO (PMID:11574543) RGD PMID:11574543 NCBI chr 5:151,110,582...151,111,854
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Smad3 SMAD family member 3 IMP RGD PMID:11839804 RGD:2301029 NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO
IEA		 MGI:1857344|MGI:1857480 (PMID:10212301), (PMID:15642323)
GO_REF:0000107		 RGD
Ensembl		 PMID:10212301 PMID:15642323 GO_REF:0000107 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Timm50 translocase of inner mitochondrial membrane 50 acts_upstream_of_or_within ISO
IEA		 (PMID:15044455)
GO_REF:0000107		 RGD
Ensembl		 PMID:15044455 GO_REF:0000107 NCBI chr 1:92,702,437...92,710,311
Ensembl chr 1:83,556,757...83,582,793 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO
IEA		 MGI:99702 (PMID:14963330), (PMID:15483136)
GO_REF:0000107		 RGD
Ensembl		 PMID:14963330 PMID:15483136 GO_REF:0000107 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp73 tumor protein p73 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
TRAIL-activated apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07018323.1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033
G Casp8 caspase 8 involved_in ISO
IEA		 (PMID:21785459)
GO_REF:0000107		 RGD
Ensembl		 PMID:21785459 GO_REF:0000107 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Fadd Fas associated via death domain involved_in ISO
IEA		 (PMID:21785459)
GO_REF:0000107		 RGD
Ensembl		 PMID:21785459 GO_REF:0000107 NCBI chr 1:209,169,245...209,175,423
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Spi1 Spi-1 proto-oncogene acts_upstream_of_positive_effect ISO
IEA		 (PMID:28362429)
GO_REF:0000107		 RGD
Ensembl		 PMID:28362429 GO_REF:0000107 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b involved_in ISO
IBA		 (PMID:19090789), (PMID:21785459)
GO_REF:0000033		 RGD
GO_Central		 PMID:19090789 PMID:21785459 GO_REF:0000033 NCBI chr15:51,249,883...51,278,091
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:208,232,371...208,252,430
Ensembl chr 1:198,802,971...198,823,418 		JBrowse link
G Tnfsf10 TNF superfamily member 10 involved_in ISO (PMID:9485194) RGD PMID:9485194 NCBI chr 2:112,136,550...112,155,903
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tradd TNFRSF1A-associated via death domain involved_in ISO (PMID:9430228) RGD PMID:9430228 NCBI chr19:50,046,057...50,048,158
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 involved_in ISO
IEA		 (PMID:22240897)
GO_REF:0000107		 RGD
Ensembl		 PMID:22240897 GO_REF:0000107 NCBI chr 8:131,602,663...131,650,998
Ensembl chr 8:122,715,111...122,773,529 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      signal transduction 7301
        apoptotic signaling pathway 687
          apoptosome assembly + 2
          extrinsic apoptotic signaling pathway + 256
          granzyme-mediated apoptotic signaling pathway 1
          hormone-mediated apoptotic signaling pathway 3
          intrinsic apoptotic signaling pathway + 348
          mitochondrial outer membrane permeabilization + 36
          negative regulation of apoptotic signaling pathway + 267
          positive regulation of apoptotic signaling pathway + 188
          regulation of apoptotic signaling pathway + 464
          release of cytochrome c from mitochondria + 63
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      cell death 2196
        programmed cell death 2196
          apoptotic process 2119
            apoptotic signaling pathway 687
              apoptosome assembly + 2
              extrinsic apoptotic signaling pathway + 256
              granzyme-mediated apoptotic signaling pathway 1
              hormone-mediated apoptotic signaling pathway 3
              intrinsic apoptotic signaling pathway + 348
              mitochondrial outer membrane permeabilization + 36
              negative regulation of apoptotic signaling pathway + 267
              positive regulation of apoptotic signaling pathway + 188
              regulation of apoptotic signaling pathway + 464
              release of cytochrome c from mitochondria + 63
paths to the root