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ONTOLOGY REPORT - ANNOTATIONS

Term:presynaptic membrane organization
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Accession:GO:0097090 term browser browse the term
Definition:A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
Comment:Note that 'presynaptic membrane' in this term should not be mistaken with 'presynaptic active zone'. The latter encompasses more than the former, as it also includes the specialized cortical cytoskeletal matrix in the cell cortex of a presynaptic neuron.
Synonyms:exact_synonym: pre-synaptic membrane organization;   presynaptic membrane organisation

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presynaptic membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cntn2 contactin 2 involved_in ISO (PMID:23518707) UniProt PMID:23518707 NCBI chrNW_004624807:6,052,591...6,080,421
Ensembl chrNW_004624807:6,056,339...6,073,588 		JBrowse link
neurexin clustering involved in presynaptic membrane assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nlgn1 neuroligin 1 involved_in ISO (PMID:12796785) BHF-UCL PMID:12796785 NCBI chrNW_004624730:51,451,546...52,300,413
Ensembl chrNW_004624730:51,650,815...52,295,023 		JBrowse link
positive regulation of presynaptic membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO (PMID:24259049) ARUK-UCL PMID:24259049 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Lrp4 LDL receptor related protein 4 involved_in ISO (PMID:22854782) UniProt PMID:22854782 NCBI chrNW_004624767:1,708,866...1,757,629 JBrowse link
presynaptic membrane assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1rapl1 interleukin 1 receptor accessory protein like 1 involved_in ISO (PMID:21940441) CACAO PMID:21940441 NCBI chrNW_004624787:266,027...1,489,032
Ensembl chrNW_004624787:268,829...1,291,144 		JBrowse link
G Lrp4 LDL receptor related protein 4 involved_in ISO (PMID:22038977) UniProt PMID:22038977 NCBI chrNW_004624767:1,708,866...1,757,629 JBrowse link
G Nlgn1 neuroligin 1 involved_in ISO PMID:15797875
(PMID:10892652), (PMID:12796785), (PMID:15620359)
PMID:19730411		 BHF-UCL PMID:10892652 PMID:12796785 PMID:15620359 PMID:15797875 PMID:19730411 RGD:8554205 RGD:8554379 NCBI chrNW_004624730:51,451,546...52,300,413
Ensembl chrNW_004624730:51,650,815...52,295,023 		JBrowse link
G Nlgn2 neuroligin 2 involved_in ISO PMID:15797875
(PMID:19016888)
(PMID:15620359)		 BHF-UCL PMID:15620359 PMID:15797875 PMID:19016888 RGD:8554205 NCBI chrNW_004624786:10,019,307...10,034,624
Ensembl chrNW_004624786:10,022,717...10,034,624 		JBrowse link
G Nlgn3 neuroligin 3 involved_in ISO PMID:15797875 BHF-UCL PMID:15797875 RGD:8554205 NCBI chrNW_004624903:1,437,663...1,465,955
Ensembl chrNW_004624903:1,438,428...1,463,172 		JBrowse link
G Nlgn4x neuroligin 4 X-linked involved_in ISO (PMID:19726642) BHF-UCL PMID:19726642 NCBI chrNW_004624834:3,646,449...4,000,328 JBrowse link
G Nrxn1 neurexin 1 involved_in ISO (PMID:12796785) BHF-UCL PMID:12796785 NCBI chrNW_004624738:31,134,551...32,273,596
Ensembl chrNW_004624738:31,133,346...32,273,565 		JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:18082964) BHF-UCL PMID:18082964 NCBI chrNW_004624791:13,975,235...14,056,900 JBrowse link
G Ptprd protein tyrosine phosphatase receptor type D involved_in ISO (PMID:21940441) BHF-UCL PMID:21940441 NCBI chrNW_004624736:12,874,884...13,558,030
Ensembl chrNW_004624736:12,874,706...13,278,956 		JBrowse link
regulation of presynaptic membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrtm4 leucine rich repeat transmembrane neuronal 4 acts_upstream_of_or_within ISO (PMID:23911104) MGI PMID:23911104 NCBI chrNW_004624749:25,669,342...26,445,401
Ensembl chrNW_004624749:25,669,348...26,444,401 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17650
    cellular process 17226
      cellular component organization or biogenesis 7005
        cellular component organization 6802
          membrane organization 763
            presynaptic membrane organization 12
              negative regulation of presynaptic membrane organization 0
              positive regulation of presynaptic membrane organization 2
              presynaptic membrane assembly + 9
              regulation of presynaptic membrane organization + 3
Path 2
Term Annotations click to browse term
  biological_process 17650
    cellular process 17226
      cellular component organization or biogenesis 7005
        cellular component organization 6802
          cell junction organization 911
            synapse organization 659
              presynaptic membrane organization 12
                negative regulation of presynaptic membrane organization 0
                positive regulation of presynaptic membrane organization 2
                presynaptic membrane assembly + 9
                regulation of presynaptic membrane organization + 3
paths to the root