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ONTOLOGY REPORT - ANNOTATIONS

Term:presynaptic membrane organization
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Accession:GO:0097090 term browser browse the term
Definition:A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
Comment:Note that 'presynaptic membrane' in this term should not be mistaken with 'presynaptic active zone'. The latter encompasses more than the former, as it also includes the specialized cortical cytoskeletal matrix in the cell cortex of a presynaptic neuron.
Synonyms:exact_synonym: pre-synaptic membrane organization;   presynaptic membrane organisation


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presynaptic membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CNTN2 contactin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:1,570,598...1,600,524
Ensembl chr38:1,576,898...1,596,621 		JBrowse link
neurexin clustering involved in presynaptic membrane assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLGN1 neuroligin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:37,397,772...38,203,634
Ensembl chr34:37,572,629...38,203,177 		JBrowse link
positive regulation of presynaptic membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO (PMID:24259049) ARUK-UCL PMID:24259049 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440 		JBrowse link
G LRP4 LDL receptor related protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,616,683...42,667,297
Ensembl chr18:42,616,426...42,665,794 		JBrowse link
presynaptic membrane assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL1RAPL1 interleukin 1 receptor accessory protein like 1 involved_in ISO (PMID:21940441) CACAO PMID:21940441 NCBI chr  X:23,747,689...25,105,606
Ensembl chr  X:23,943,871...25,099,377 		JBrowse link
G LRP4 LDL receptor related protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,616,683...42,667,297
Ensembl chr18:42,616,426...42,665,794 		JBrowse link
G NLGN1 neuroligin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:37,397,772...38,203,634
Ensembl chr34:37,572,629...38,203,177 		JBrowse link
G NLGN2 neuroligin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,338,602...32,351,546
Ensembl chr 5:32,340,335...32,352,412 		JBrowse link
G NLGN3 neuroligin 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:55,510,729...55,532,396
Ensembl chr  X:55,513,626...55,531,371 		JBrowse link
G NLGN4X neuroligin 4 X-linked involved_in ISO (PMID:19726642) BHF-UCL PMID:19726642 NCBI chr  X:3,409,529...3,708,234 JBrowse link
G NRXN1 neurexin 1 involved_in ISO (PMID:12796785) BHF-UCL PMID:12796785 NCBI chr10:51,555,660...52,666,774
Ensembl chr10:51,558,452...52,667,569 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:18082964) BHF-UCL PMID:18082964 NCBI chr26:37,853,148...37,913,176
Ensembl chr26:37,835,661...37,913,176 		JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D involved_in ISO (PMID:21940441) CACAO PMID:21940441 NCBI chr11:29,100,913...31,278,495
Ensembl chr11:29,104,448...29,501,600 		JBrowse link
regulation of presynaptic membrane organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRTM4 leucine rich repeat transmembrane neuronal 4 acts_upstream_of_or_within ISO (PMID:23911104) MGI PMID:23911104 NCBI chr17:46,091,140...46,797,107
Ensembl chr17:46,090,978...46,796,020 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    cellular process 21672
      cellular component organization or biogenesis 10063
        cellular component organization 9831
          membrane organization 823
            presynaptic membrane organization 12
              negative regulation of presynaptic membrane organization 0
              positive regulation of presynaptic membrane organization 2
              presynaptic membrane assembly + 9
              regulation of presynaptic membrane organization + 3
Path 2
Term Annotations click to browse term
  biological_process 22141
    cellular process 21672
      cellular component organization or biogenesis 10063
        cellular component organization 9831
          cell junction organization 970
            synapse organization 699
              presynaptic membrane organization 12
                negative regulation of presynaptic membrane organization 0
                positive regulation of presynaptic membrane organization 2
                presynaptic membrane assembly + 9
                regulation of presynaptic membrane organization + 3
paths to the root