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ONTOLOGY REPORT - ANNOTATIONS


Term:dendritic spine maintenance
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Accession:GO:0097062 term browser browse the term
Definition:The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.


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dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23365224) MGI PMID:23365224 NCBI chrNW_004936481:9,823,790...9,847,291
Ensembl chrNW_004936481:9,824,392...9,847,104
JBrowse link
G Ckap5 cytoskeleton associated protein 5 acts_upstream_of_or_within ISO (PMID:23936366) MGI PMID:23936366 NCBI chrNW_004936562:2,269,341...2,369,098
Ensembl chrNW_004936562:2,269,332...2,371,224
JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO (PMID:31141683) MGI PMID:31141683 NCBI chrNW_004936527:2,859,442...4,748,885
Ensembl chrNW_004936527:2,859,930...4,746,995
JBrowse link
G Cttn cortactin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23365224) Ensembl
MGI
PMID:23365224 GO_REF:0000107 NCBI chrNW_004936599:481,234...503,857
Ensembl chrNW_004936599:481,243...501,743
JBrowse link
G Igf1r insulin like growth factor 1 receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chrNW_004936483:4,563,995...4,860,231
Ensembl chrNW_004936483:4,564,512...4,852,925
JBrowse link
G Insr insulin receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chrNW_004936588:4,345,306...4,453,380
Ensembl chrNW_004936588:4,345,306...4,453,668
JBrowse link
G Itga3 integrin subunit alpha 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23595732) Ensembl
MGI
PMID:23595732 GO_REF:0000107 NCBI chrNW_004936490:11,553,904...11,583,387
Ensembl chrNW_004936490:11,553,861...11,583,380
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A acts_upstream_of_or_within ISO PMID:19890013 MGI PMID:19890013 RGD:8553536 NCBI chrNW_004936471:4,840,113...4,848,881
Ensembl chrNW_004936471:4,840,152...4,848,881
JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in ISO PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chrNW_004936700:1,790,592...1,873,019
Ensembl chrNW_004936700:1,790,064...1,873,034
JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936492:3,098,196...3,115,921
Ensembl chrNW_004936492:3,097,629...3,116,526
JBrowse link
G Tanc1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21068316) Ensembl
MGI
PMID:21068316 GO_REF:0000107 NCBI chrNW_004936469:19,428,035...19,651,913
Ensembl chrNW_004936469:19,425,479...19,651,976
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:18,659,725...18,665,406
Ensembl chrNW_004936476:18,659,815...18,663,940
JBrowse link
negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Cfl1 cofilin 1 ISO RGD PMID:23974706 RGD:11570553 NCBI chrNW_004936599:3,678,724...3,682,314
Ensembl chrNW_004936599:3,677,804...3,682,307
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936679:388,500...588,518
Ensembl chrNW_004936679:387,387...443,880
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO (PMID:22820466) ARUK-UCL PMID:22820466 NCBI chrNW_004936587:3,406,055...3,806,956
Ensembl chrNW_004936587:3,405,698...3,804,664
JBrowse link
G Prnp prion protein (Kanno blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936485:14,104,829...14,118,614
Ensembl chrNW_004936485:14,104,831...14,118,629
JBrowse link
positive regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:30206770 RGD:405650589 NCBI chrNW_004936586:4,065,767...5,100,690
Ensembl chrNW_004936586:4,066,498...5,100,035
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO PMID:17360908 ARUK-UCL PMID:17360908 RGD:12793018 NCBI chrNW_004936669:814,330...838,881
Ensembl chrNW_004936669:814,330...839,208
JBrowse link
G Ins insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936816:1,002,137...1,003,357
Ensembl chrNW_004936816:1,002,137...1,003,357
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936534:1,816,755...1,863,200
Ensembl chrNW_004936534:1,760,142...1,863,565
JBrowse link
G Zmynd8 zinc finger MYND-type containing 8 ISO RGD PMID:24117785 RGD:8554267 NCBI chrNW_004936514:6,116,789...6,214,383
Ensembl chrNW_004936514:6,116,676...6,212,996
JBrowse link
G Znf804a zinc finger protein 804A involved_in ISO PMID:27837918 UniProt PMID:27837918 RGD:13210564 NCBI chrNW_004936506:12,164,004...12,450,483
Ensembl chrNW_004936506:12,164,469...12,167,690
JBrowse link
regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17b abhydrolase domain containing 17B, depalmitoylase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936503:7,902,116...7,943,300
Ensembl chrNW_004936503:7,901,522...7,943,300
JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chrNW_004936640:1,549,977...1,787,436
Ensembl chrNW_004936640:1,550,167...1,787,286
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chrNW_004937131:80,014...96,114 JBrowse link
G Homer1 homer scaffold protein 1 involved_in ISO PMID:19345194 UniProt PMID:19345194 RGD:8553291 NCBI chrNW_004936549:7,189,588...7,320,117
Ensembl chrNW_004936549:7,188,850...7,320,312
JBrowse link
G Vps35 VPS35 retromer complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936475:50,476...77,797
Ensembl chrNW_004936475:50,321...78,097
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17407
    cellular process 17010
      cellular component organization or biogenesis 7534
        cellular component organization 7340
          cellular component maintenance 95
            dendritic spine maintenance 28
              negative regulation of dendritic spine maintenance 5
              positive regulation of dendritic spine maintenance 7
              regulation of dendritic spine maintenance + 16
Path 2
Term Annotations click to browse term
  biological_process 17407
    cellular process 17010
      cellular component organization or biogenesis 7534
        cellular component organization 7340
          cell junction organization 913
            synapse organization 666
              postsynapse organization 319
                dendritic spine organization 110
                  dendritic spine maintenance 28
                    negative regulation of dendritic spine maintenance 5
                    positive regulation of dendritic spine maintenance 7
                    regulation of dendritic spine maintenance + 16
paths to the root