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ONTOLOGY REPORT - ANNOTATIONS

Term:dendritic spine maintenance
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Accession:GO:0097062 term browser browse the term
Definition:The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.


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dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23365224) MGI PMID:23365224 NCBI chr 9:120,888,891...120,984,724
Ensembl chr 9:120,892,952...120,984,695 		JBrowse link
G CKAP5 cytoskeleton associated protein 5 acts_upstream_of_or_within ISO (PMID:23936366) MGI PMID:23936366 NCBI chr 2:15,680,723...15,790,580
Ensembl chr 2:15,680,787...15,790,569 		JBrowse link
G CNTNAP2 contactin associated protein 2 involved_in ISO (PMID:31141683) MGI PMID:31141683 NCBI chr 9:109,740,510...111,781,144 JBrowse link
G CTTN cortactin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23365224) Ensembl
MGI		 PMID:23365224 GO_REF:0000107 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,103...3,060,813 		JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058 		JBrowse link
G INSR insulin receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chr 2:71,797,209...71,939,923
Ensembl chr 2:71,797,204...71,936,104 		JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23595732) Ensembl
MGI		 PMID:23595732 GO_REF:0000107 NCBI chr12:26,234,769...26,269,327
Ensembl chr12:26,235,258...26,269,324 		JBrowse link
G ITPKA inositol-trisphosphate 3-kinase A acts_upstream_of_or_within ISO PMID:19890013 MGI PMID:19890013 RGD:8553536 NCBI chr 1:129,867,261...129,877,762
Ensembl chr 1:129,867,642...129,875,639 		JBrowse link
G MTMR2 myotubularin related protein 2 involved_in ISO PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 9:27,864,335...27,974,448
Ensembl chr 9:27,854,491...27,974,423 		JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:9,808,444...9,829,677
Ensembl chr 5:9,808,451...9,825,539 		JBrowse link
G TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21068316) Ensembl
MGI		 PMID:21068316 GO_REF:0000107 NCBI chr15:65,920,168...66,166,000
Ensembl chr15:65,920,292...66,165,991 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31980586) ARUK-UCL PMID:31980586 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516 		JBrowse link
negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23974706 RGD:11570553 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035 		JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:77,584,675...77,810,605
Ensembl chr 1:77,585,439...77,810,581 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO (PMID:22820466) ARUK-UCL PMID:22820466 NCBI chr 5:58,477,862...58,948,735
Ensembl chr 5:58,480,528...58,927,558 		JBrowse link
G PRNP prion protein involved_in ISO (PMID:24012003)
(PMID:22820466)		 ARUK-UCL PMID:22820466 PMID:24012003 NCBI chr17:13,694,195...13,705,126
Ensembl chr17:13,694,190...13,705,124 		JBrowse link
positive regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24328732) Alzheimers_University_of_Toronto
Ensembl		 PMID:24328732 GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:30206770 RGD:405650589 NCBI chr15:113,966,573...115,096,984
Ensembl chr15:113,974,437...115,096,565 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO PMID:17360908 ARUK-UCL PMID:17360908 RGD:12793018
G INS insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G NEDD9 neural precursor cell expressed, developmentally down-regulated 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:7,807,042...8,093,553
Ensembl chr 7:7,807,044...7,914,061 		JBrowse link
G ZMYND8 zinc finger MYND-type containing 8 ISO RGD PMID:24117785 RGD:8554267 NCBI chr17:49,258,543...49,390,418
Ensembl chr17:49,258,542...49,390,399 		JBrowse link
G ZNF804A zinc finger protein 804A involved_in ISO PMID:27837918 UniProt PMID:27837918 RGD:13210564 NCBI chr15:89,842,424...90,150,352
Ensembl chr15:89,842,769...90,150,347 		JBrowse link
regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD17B abhydrolase domain containing 17B, depalmitoylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:225,149,922...225,193,329
Ensembl chr 1:225,150,682...225,193,287 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chr 4:88,873,762...88,892,964 JBrowse link
G HOMER1 homer scaffold protein 1 involved_in ISO PMID:19345194 UniProt PMID:19345194 RGD:8553291 NCBI chr 2:88,116,664...88,253,843
Ensembl chr 2:88,122,882...88,255,281 		JBrowse link
G VPS35 VPS35 retromer complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:37,944,099...37,977,091
Ensembl chr 6:37,944,127...37,986,171 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18954
    cellular process 18495
      cellular component organization or biogenesis 7489
        cellular component organization 7284
          cellular component maintenance 98
            dendritic spine maintenance 28
              negative regulation of dendritic spine maintenance 5
              positive regulation of dendritic spine maintenance 7
              regulation of dendritic spine maintenance + 16
Path 2
Term Annotations click to browse term
  biological_process 18954
    cellular process 18495
      cellular component organization or biogenesis 7489
        cellular component organization 7284
          cell junction organization 955
            synapse organization 684
              postsynapse organization 323
                dendritic spine organization 110
                  dendritic spine maintenance 28
                    negative regulation of dendritic spine maintenance 5
                    positive regulation of dendritic spine maintenance 7
                    regulation of dendritic spine maintenance + 16
paths to the root