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ONTOLOGY REPORT - ANNOTATIONS


Term:dendritic spine maintenance
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Accession:GO:0097062 term browser browse the term
Definition:The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.


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dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23365224) MGI PMID:23365224 NCBI chrNW_004624771:3,160,528...3,280,860
Ensembl chrNW_004624771:3,160,224...3,278,787
JBrowse link
G Ckap5 cytoskeleton associated protein 5 acts_upstream_of_or_within ISO (PMID:23936366) MGI PMID:23936366 NCBI chrNW_004624767:1,761,983...1,874,534
Ensembl chrNW_004624767:1,761,733...1,874,534
JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO (PMID:31141683) MGI PMID:31141683 NCBI chrNW_004624800:7,182,588...9,280,407
Ensembl chrNW_004624800:7,181,020...9,279,678
JBrowse link
G Cttn cortactin acts_upstream_of_or_within ISO (PMID:23365224) MGI PMID:23365224 NCBI chrNW_004624767:16,842,341...16,884,449
Ensembl chrNW_004624767:16,847,459...16,880,183
JBrowse link
G Igf1r insulin like growth factor 1 receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chrNW_004624768:5,396,027...5,688,435
Ensembl chrNW_004624768:5,396,156...5,681,809
JBrowse link
G Insr insulin receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chrNW_004624828:345,135...485,856
Ensembl chrNW_004624828:345,135...486,184
JBrowse link
G Itga3 integrin subunit alpha 3 acts_upstream_of_or_within ISO (PMID:23595732) MGI PMID:23595732 NCBI chrNW_004624795:6,062,438...6,092,556
Ensembl chrNW_004624795:6,062,290...6,092,557
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A acts_upstream_of_or_within ISO PMID:19890013 MGI PMID:19890013 RGD:8553536 NCBI chrNW_004624804:8,655,762...8,664,599
Ensembl chrNW_004624804:8,655,777...8,664,600
JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in ISO PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chrNW_004624735:40,673,156...40,770,693 JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624752:9,880,773...9,895,270
Ensembl chrNW_004624752:9,880,670...9,895,230
JBrowse link
G Tanc1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 acts_upstream_of_or_within ISO (PMID:21068316) MGI PMID:21068316 NCBI chrNW_004624732:6,421,061...6,672,724
Ensembl chrNW_004624732:6,421,066...6,672,213
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31980586) ARUK-UCL PMID:31980586 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231
JBrowse link
negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Cfl1 cofilin 1 ISO RGD PMID:23974706 RGD:11570553 NCBI chrNW_004624767:20,574,884...20,578,413
Ensembl chrNW_004624767:20,574,966...20,579,796
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:22820466) ARUK-UCL PMID:22820466 NCBI chrNW_004624933:248,298...456,933
Ensembl chrNW_004624933:389,627...456,520
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO (PMID:22820466) ARUK-UCL PMID:22820466 NCBI chrNW_004624752:24,008,520...24,480,834
Ensembl chrNW_004624752:24,135,487...24,459,288
JBrowse link
G Prnp prion protein (Kanno blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624741:5,785,139...5,802,162
Ensembl chrNW_004624741:5,785,158...5,802,162
JBrowse link
positive regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chrNW_004624907:1,752,322...1,755,308 JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:30206770 RGD:405650589 NCBI chrNW_004624765:3,612,781...4,742,219
Ensembl chrNW_004624765:3,613,379...4,734,585
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO PMID:17360908 ARUK-UCL PMID:17360908 RGD:12793018 NCBI chrNW_004624760:777,208...800,525
Ensembl chrNW_004624760:776,873...801,354
JBrowse link
G Ins insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624767:14,999,088...15,000,035
Ensembl chrNW_004624767:14,999,088...15,000,035
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 involved_in ISO (PMID:26683084) UniProt PMID:26683084 NCBI chrNW_004624756:14,663,114...14,850,132
Ensembl chrNW_004624756:14,737,054...14,850,708
JBrowse link
G Zmynd8 zinc finger MYND-type containing 8 ISO RGD PMID:24117785 RGD:8554267 NCBI chrNW_004624790:7,473,739...7,611,612
Ensembl chrNW_004624790:7,493,066...7,611,485
JBrowse link
G Znf804a zinc finger protein 804A involved_in ISO PMID:27837918 UniProt PMID:27837918 RGD:13210564 NCBI chrNW_004624844:6,417,102...6,482,516 JBrowse link
regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17b abhydrolase domain containing 17B, depalmitoylase involved_in ISO (PMID:27307232) UniProt PMID:27307232 NCBI chrNW_004624736:1,175,103...1,218,251
Ensembl chrNW_004624736:1,201,988...1,214,971
JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chrNW_004624745:13,904,912...14,159,374
Ensembl chrNW_004624745:13,902,577...14,159,372
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chrNW_004624826:97,605...112,101 JBrowse link
G Homer1 homer scaffold protein 1 involved_in ISO PMID:19345194 UniProt PMID:19345194 RGD:8553291 NCBI chrNW_004624869:3,878,646...4,012,211
Ensembl chrNW_004624869:3,880,001...4,012,240
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:26618722) ParkinsonsUK-UCL PMID:26618722 NCBI chrNW_004624914:160,483...188,534
Ensembl chrNW_004624914:160,483...188,490
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17638
    cellular process 17218
      cellular component organization or biogenesis 7065
        cellular component organization 6865
          cellular component maintenance 93
            dendritic spine maintenance 28
              negative regulation of dendritic spine maintenance 5
              positive regulation of dendritic spine maintenance 7
              regulation of dendritic spine maintenance + 16
Path 2
Term Annotations click to browse term
  biological_process 17638
    cellular process 17218
      cellular component organization or biogenesis 7065
        cellular component organization 6865
          cell junction organization 911
            synapse organization 658
              postsynapse organization 315
                dendritic spine organization 108
                  dendritic spine maintenance 28
                    negative regulation of dendritic spine maintenance 5
                    positive regulation of dendritic spine maintenance 7
                    regulation of dendritic spine maintenance + 16
paths to the root