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ONTOLOGY REPORT - ANNOTATIONS


Term:dendritic spine maintenance
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Accession:GO:0097062 term browser browse the term
Definition:The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.



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dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23365224) MGI PMID:23365224 NCBI chr 1:179,099,330...179,229,677
Ensembl chr 1:179,099,330...179,229,684
JBrowse link
G CKAP5 cytoskeleton associated protein 5 acts_upstream_of_or_within ISO (PMID:23936366) MGI PMID:23936366 NCBI chr11:46,743,048...46,846,280
Ensembl chr11:46,743,048...46,846,308
JBrowse link
G CNTNAP2 contactin associated protein 2 involved_in ISO (PMID:31141683) MGI PMID:31141683 NCBI chr 7:146,116,801...148,420,998
Ensembl chr 7:146,116,002...148,420,998
JBrowse link
G CTTN cortactin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23365224) Ensembl
MGI
PMID:23365224 GO_REF:0000107 NCBI chr11:70,398,529...70,436,575
Ensembl chr11:70,398,404...70,436,584
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in TAS (PMID:25707991) ARUK-UCL PMID:25707991 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in IEA
ISS
(PMID:19406747) Ensembl
ARUK-UCL
PMID:19406747 GO_REF:0000107 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530
JBrowse link
G INSR insulin receptor involved_in ISS (PMID:19406747) ARUK-UCL PMID:19406747 NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414
JBrowse link
G ITGA3 integrin subunit alpha 3 acts_upstream_of_or_within
involved_in
ISS
IEA
ARUK-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:50,056,110...50,090,481
Ensembl chr17:50,055,968...50,090,481
JBrowse link
G ITPKA inositol-trisphosphate 3-kinase A acts_upstream_of_or_within
involved_in
ISO
IEA
PMID:19890013 MGI
Ensembl
PMID:19890013 GO_REF:0000107 RGD:8553536 NCBI chr15:41,493,874...41,503,551
Ensembl chr15:41,493,393...41,503,551
JBrowse link
G MTMR2 myotubularin related protein 2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:95,832,880...95,924,107
Ensembl chr11:95,821,766...95,925,315
JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in ISS
IBA
UniProt
GO_Central
GO_REF:0000024 GO_REF:0000033 NCBI chr22:38,057,255...38,075,701
Ensembl chr22:38,056,311...38,075,701
JBrowse link
G PRNP prion protein (Kanno blood group) involved_in TAS (PMID:25707991) ARUK-UCL PMID:25707991 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590
JBrowse link
G TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:21068316) Ensembl
MGI
PMID:21068316 GO_REF:0000107 NCBI chr 2:158,968,640...159,232,659
Ensembl chr 2:158,968,640...159,232,659
JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISS
IEA
ARUK-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186
JBrowse link
negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within IDA (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23974706 RGD:11570553 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in ISS
IEA
ARUK-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002
JBrowse link
G MIR30B microRNA 30b involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 8:134,800,520...134,800,607
Ensembl chr 8:134,800,520...134,800,607
JBrowse link
G PRNP prion protein (Kanno blood group) involved_in ISS
IEA
ARUK-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr20:4,686,456...4,701,588
Ensembl chr20:4,686,350...4,701,590
JBrowse link
positive regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within IDA (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:30206770 RGD:405650589 NCBI chr 2:211,375,717...212,538,802
Ensembl chr 2:211,375,717...212,538,841
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO PMID:17360908 ARUK-UCL PMID:17360908 RGD:12793018 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
JBrowse link
G INS insulin involved_in IGI (PMID:19188609) ARUK-UCL PMID:19188609 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221
JBrowse link
G NEDD9 neural precursor cell expressed, developmentally down-regulated 9 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:11,183,298...11,382,348
Ensembl chr 6:11,183,298...11,382,348
JBrowse link
G ZMYND8 zinc finger MYND-type containing 8 involved_in ISO
IEA
RGD
Ensembl
PMID:24117785 GO_REF:0000107 RGD:8554267 NCBI chr20:47,209,214...47,356,699
Ensembl chr20:47,209,214...47,356,889
JBrowse link
G ZNF804A zinc finger protein 804A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:184,598,529...184,939,492
Ensembl chr 2:184,598,529...184,939,492
JBrowse link
regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD17B abhydrolase domain containing 17B, depalmitoylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:71,862,452...71,911,193
Ensembl chr 9:71,862,452...71,911,193
JBrowse link
G APP amyloid beta precursor protein involved_in IGI (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
JBrowse link
G FCGR2B Fc gamma receptor IIb involved_in IGI (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654
JBrowse link
G HOMER1 homer scaffold protein 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134
JBrowse link
G VPS35 VPS35 retromer complex component involved_in IMP (PMID:26618722) ParkinsonsUK-UCL PMID:26618722 NCBI chr16:46,656,132...46,689,178
Ensembl chr16:46,656,132...46,689,518
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20482
    cellular process 19724
      cellular component organization or biogenesis 7902
        cellular component organization 7672
          cellular component maintenance 105
            dendritic spine maintenance 29
              negative regulation of dendritic spine maintenance 6
              positive regulation of dendritic spine maintenance 7
              regulation of dendritic spine maintenance + 17
Path 2
Term Annotations click to browse term
  biological_process 20482
    cellular process 19724
      cellular component organization or biogenesis 7902
        cellular component organization 7672
          cell junction organization 1011
            synapse organization 730
              postsynapse organization 336
                dendritic spine organization 114
                  dendritic spine maintenance 29
                    negative regulation of dendritic spine maintenance 6
                    positive regulation of dendritic spine maintenance 7
                    regulation of dendritic spine maintenance + 17
paths to the root