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ONTOLOGY REPORT - ANNOTATIONS


Term:dendritic spine maintenance
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Accession:GO:0097062 term browser browse the term
Definition:The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.



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dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23365224) MGI PMID:23365224 NCBI chr 7:20,696,659...20,735,362
Ensembl chr 7:20,700,144...20,727,410
JBrowse link
G CKAP5 cytoskeleton associated protein 5 acts_upstream_of_or_within ISO (PMID:23936366) MGI PMID:23936366 NCBI chr18:42,673,432...42,780,320
Ensembl chr18:42,711,471...42,780,090
JBrowse link
G CNTNAP2 contactin associated protein 2 involved_in ISO (PMID:31141683) MGI PMID:31141683 NCBI chr16:2,239,953...4,208,718
Ensembl chr16:2,243,918...4,208,416
JBrowse link
G CTTN cortactin involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23365224) Ensembl
MGI
PMID:23365224 GO_REF:0000107 NCBI chr18:47,932,367...47,960,732
Ensembl chr18:47,916,632...47,960,674
JBrowse link
G IGF1R insulin like growth factor 1 receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chr 3:41,795,337...42,096,255
Ensembl chr 3:41,794,623...42,090,387
JBrowse link
G INSR insulin receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chr20:52,017,261...52,136,061
Ensembl chr20:52,021,887...52,136,046
JBrowse link
G ITGA3 integrin subunit alpha 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23595732) Ensembl
MGI
PMID:23595732 GO_REF:0000107 NCBI chr 9:26,065,792...26,095,649
Ensembl chr 9:26,062,393...26,094,422
JBrowse link
G ITPKA inositol-trisphosphate 3-kinase A acts_upstream_of_or_within ISO PMID:19890013 MGI PMID:19890013 RGD:8553536 NCBI chr30:8,532,191...8,541,273
Ensembl chr30:8,532,284...8,541,285
JBrowse link
G MTMR2 myotubularin related protein 2 involved_in ISO PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr21:5,194,772...5,316,441
Ensembl chr21:5,194,604...5,315,375
JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr10:26,595,301...26,614,170
Ensembl chr10:26,595,768...26,613,756
JBrowse link
G TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 acts_upstream_of_or_within ISO (PMID:21068316) MGI PMID:21068316 NCBI chr36:4,850,214...5,019,453
Ensembl chr36:4,899,174...5,021,132
JBrowse link
negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23974706 RGD:11570553 NCBI chr18:51,404,649...51,408,240
Ensembl chr18:51,401,659...51,408,212
JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:68,105,060...68,316,630
Ensembl chr12:68,075,184...68,316,541
JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO (PMID:22820466) ARUK-UCL PMID:22820466 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680
JBrowse link
G PRNP prion protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:16,845,224...16,862,319
Ensembl chr24:16,846,207...16,859,815
JBrowse link
positive regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:24328732) Alzheimers_University_of_Toronto
Ensembl
PMID:24328732 GO_REF:0000107 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G ERBB4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:30206770 RGD:405650589 NCBI chr37:19,029,647...20,134,576
Ensembl chr37:19,037,217...20,134,426
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO PMID:17360908 ARUK-UCL PMID:17360908 RGD:12793018 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050
JBrowse link
G INS insulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,324,047...46,324,933
Ensembl chr18:46,324,041...46,325,122
JBrowse link
G NEDD9 neural precursor cell expressed, developmentally down-regulated 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:10,852,334...11,033,656
Ensembl chr35:10,854,295...10,964,650
JBrowse link
G ZMYND8 zinc finger MYND-type containing 8 ISO RGD PMID:24117785 RGD:8554267 NCBI chr24:34,322,364...34,466,044
Ensembl chr24:34,321,570...34,485,544
JBrowse link
G ZNF804A zinc finger protein 804A involved_in ISO PMID:27837918 UniProt PMID:27837918 RGD:13210564 NCBI chr36:27,453,839...27,527,770
Ensembl chr36:27,458,938...27,527,362
JBrowse link
regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD17B abhydrolase domain containing 17B, depalmitoylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:85,806,873...85,861,051
Ensembl chr 1:85,807,511...85,863,551
JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337
JBrowse link
G FCGR2B Fc fragment of IgG receptor IIb involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chr38:20,980,777...20,994,403 JBrowse link
G HOMER1 homer scaffold protein 1 involved_in ISO PMID:19345194 UniProt PMID:19345194 RGD:8553291 NCBI chr 3:27,395,337...27,525,822
Ensembl chr 3:27,400,839...27,523,320
JBrowse link
G VPS35 VPS35 retromer complex component involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:8,428,073...8,454,601
Ensembl chr15:8,428,172...8,454,049
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22098
    cellular process 21628
      cellular component organization or biogenesis 10028
        cellular component organization 9797
          cellular component maintenance 97
            dendritic spine maintenance 27
              negative regulation of dendritic spine maintenance 5
              positive regulation of dendritic spine maintenance 7
              regulation of dendritic spine maintenance + 16
Path 2
Term Annotations click to browse term
  biological_process 22098
    cellular process 21628
      cellular component organization or biogenesis 10028
        cellular component organization 9797
          cell junction organization 966
            synapse organization 695
              postsynapse organization 325
                dendritic spine organization 110
                  dendritic spine maintenance 27
                    negative regulation of dendritic spine maintenance 5
                    positive regulation of dendritic spine maintenance 7
                    regulation of dendritic spine maintenance + 16
paths to the root