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ONTOLOGY REPORT - ANNOTATIONS


Term:dendritic spine maintenance
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Accession:GO:0097062 term browser browse the term
Definition:The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.


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dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:23365224) MGI PMID:23365224 NCBI chrNW_004955406:18,435,984...18,527,967
Ensembl chrNW_004955406:18,437,672...18,527,698
JBrowse link
G Ckap5 cytoskeleton associated protein 5 acts_upstream_of_or_within ISO (PMID:23936366) MGI PMID:23936366 NCBI chrNW_004955422:1,266,686...1,354,323
Ensembl chrNW_004955422:1,279,158...1,353,894
JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO (PMID:31141683) MGI PMID:31141683 NCBI chrNW_004955491:1,983,002...3,982,510
Ensembl chrNW_004955491:1,984,050...3,981,830
JBrowse link
G Cttn cortactin acts_upstream_of_or_within ISO (PMID:23365224) MGI PMID:23365224 NCBI chrNW_004955422:15,838,036...15,874,067
Ensembl chrNW_004955422:15,835,145...15,874,108
JBrowse link
G Igf1r insulin like growth factor 1 receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chrNW_004955416:26,101,090...26,382,660
Ensembl chrNW_004955416:26,102,628...26,382,666
JBrowse link
G Insr insulin receptor involved_in ISO PMID:19406747 ARUK-UCL PMID:19406747 RGD:13210538 NCBI chrNW_004955563:1,867,400...2,011,845
Ensembl chrNW_004955563:1,867,400...2,009,149
JBrowse link
G Itga3 integrin subunit alpha 3 acts_upstream_of_or_within ISO (PMID:23595732) MGI PMID:23595732 NCBI chrNW_004955451:11,563,120...11,590,119
Ensembl chrNW_004955451:11,561,704...11,589,727
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A acts_upstream_of_or_within ISO PMID:19890013 MGI PMID:19890013 RGD:8553536 NCBI chrNW_004955416:8,300,059...8,310,225
Ensembl chrNW_004955416:8,299,318...8,309,865
JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in ISO PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chrNW_004955412:693,743...764,377
Ensembl chrNW_004955412:693,743...750,154
JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in ISO PMID:18297063 UniProt PMID:18297063 RGD:8554748 NCBI chrNW_004955413:24,383,130...24,399,092
Ensembl chrNW_004955413:24,383,130...24,399,196
JBrowse link
G Tanc1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 acts_upstream_of_or_within ISO (PMID:21068316) MGI PMID:21068316 NCBI chrNW_004955449:14,353,693...14,586,010
Ensembl chrNW_004955449:14,353,693...14,530,861
JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:31980586) ARUK-UCL PMID:31980586 NCBI chrNW_004955437:7,780,886...7,785,597
Ensembl chrNW_004955437:7,780,679...7,785,697
JBrowse link
negative regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Cfl1 cofilin 1 ISO RGD PMID:23974706 RGD:11570553 NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in ISO (PMID:22820466) ARUK-UCL PMID:22820466 NCBI chrNW_004955411:36,403,156...36,597,660
Ensembl chrNW_004955411:36,401,842...36,512,054
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO (PMID:22820466) ARUK-UCL PMID:22820466 NCBI chrNW_004955413:10,358,931...10,780,004
Ensembl chrNW_004955413:10,376,597...10,779,145
JBrowse link
G Prnp prion protein (Kanno blood group) involved_in ISO (PMID:24012003)
(PMID:22820466)
ARUK-UCL PMID:22820466 PMID:24012003 NCBI chrNW_004955415:15,442,313...15,454,644
Ensembl chrNW_004955415:15,442,313...15,454,644
JBrowse link
positive regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E acts_upstream_of_or_within ISO (PMID:24328732) Alzheimers_University_of_Toronto PMID:24328732 NCBI chrNW_004955555:1,998,170...2,002,003
Ensembl chrNW_004955555:1,999,711...2,001,888
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 ISO RGD PMID:30206770 RGD:405650589 NCBI chrNW_004955457:3,177,905...4,236,152
Ensembl chrNW_004955457:3,177,991...4,228,558
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO PMID:17360908 ARUK-UCL PMID:17360908 RGD:12793018 NCBI chrNW_004955513:5,154,864...5,178,636
Ensembl chrNW_004955513:5,154,864...5,178,636
JBrowse link
G Ins insulin involved_in ISO (PMID:19188609) ARUK-UCL PMID:19188609 NCBI chrNW_004955422:13,909,408...13,910,419
Ensembl chrNW_004955422:13,909,407...13,910,419
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 involved_in ISO (PMID:26683084) UniProt PMID:26683084 NCBI chrNW_004955465:3,101,409...3,281,481
Ensembl chrNW_004955465:3,129,707...3,282,632
JBrowse link
G Zmynd8 zinc finger MYND-type containing 8 ISO RGD PMID:24117785 RGD:8554267 NCBI chrNW_004955445:10,226,031...10,361,371
Ensembl chrNW_004955445:10,229,902...10,363,350
JBrowse link
G Znf804a zinc finger protein 804A involved_in ISO PMID:27837918 UniProt PMID:27837918 RGD:13210564 NCBI chrNW_004955403:12,935,722...13,201,523 JBrowse link
regulation of dendritic spine maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd17b abhydrolase domain containing 17B, depalmitoylase involved_in ISO (PMID:27307232) UniProt PMID:27307232 NCBI chrNW_004955434:1,262,956...1,302,877
Ensembl chrNW_004955434:1,262,264...1,302,496
JBrowse link
G App amyloid beta precursor protein involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chrNW_004955407:25,725,259...25,973,582
Ensembl chrNW_004955407:25,722,849...25,974,268
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb involved_in ISO (PMID:23921129) ARUK-UCL PMID:23921129 NCBI chrNW_004955462:14,639,396...14,653,801 JBrowse link
G Homer1 homer scaffold protein 1 involved_in ISO PMID:19345194 UniProt PMID:19345194 RGD:8553291 NCBI chrNW_004955425:21,644,577...21,774,843
Ensembl chrNW_004955425:21,644,571...21,775,735
JBrowse link
G Vps35 VPS35 retromer complex component involved_in ISO (PMID:26618722) ParkinsonsUK-UCL PMID:26618722 NCBI chrNW_004955448:207,582...240,264
Ensembl chrNW_004955448:204,991...240,160
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12561
    cellular process 12000
      cellular component organization or biogenesis 5408
        cellular component organization 5280
          cellular component maintenance 83
            dendritic spine maintenance 28
              negative regulation of dendritic spine maintenance 5
              positive regulation of dendritic spine maintenance 7
              regulation of dendritic spine maintenance + 16
Path 2
Term Annotations click to browse term
  biological_process 12561
    cellular process 12000
      cellular component organization or biogenesis 5408
        cellular component organization 5280
          cell junction organization 860
            synapse organization 634
              postsynapse organization 311
                dendritic spine organization 107
                  dendritic spine maintenance 28
                    negative regulation of dendritic spine maintenance 5
                    positive regulation of dendritic spine maintenance 7
                    regulation of dendritic spine maintenance + 16
paths to the root