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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of excitatory postsynaptic potential
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Accession:GO:0090394 term browser browse the term
Definition:Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
Synonyms:exact_synonym: negative regulation of excitatory post-synaptic membrane potential;   reduction of excitatory postsynaptic membrane potential
 related_synonym: negative regulation of EPSP



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negative regulation of excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbln1 cerebellin 1 precursor involved_in ISO (PMID:27418511) RGD PMID:27418511 NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572
JBrowse link
G Celf4 CUGBP, Elav-like family member 4 acts_upstream_of_or_within ISO MGI:5425630 (PMID:21745337) RGD PMID:21745337 NCBI chr18:16,786,578...17,065,045
Ensembl chr18:16,786,867...17,064,786
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 IMP RGD PMID:17632064 RGD:10044262 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:21307259) RGD PMID:21307259 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mtmr2 myotubularin related protein 2 involved_in IMP PMID:20410104 BHF-UCL PMID:20410104 RGD:8553482 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
G Nlgn3 neuroligin 3 involved_in ISO (PMID:21808020) RGD PMID:21808020 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IDA RGD PMID:12055128 RGD:1642608 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024
JBrowse link
G Plk2 polo-like kinase 2 IMP RGD PMID:20802490 RGD:152995511 NCBI chr 2:41,969,176...41,974,945
Ensembl chr 2:41,969,176...41,974,947
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:19033459 RGD:10413844 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:21411674) RGD PMID:21411674 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G S1pr2 sphingosine-1-phosphate receptor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180817 (PMID:11553273)
Ensembl
RGD
PMID:11553273 GO_REF:0000107 NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574
JBrowse link
G Tmem25 transmembrane protein 25 involved_in IBA
ISO
GO_REF:0000033
(PMID:31424425)
GO_Central
RGD
PMID:31424425 GO_REF:0000033 NCBI chr 8:45,107,116...45,112,657
Ensembl chr 8:45,107,121...45,116,389
JBrowse link
negative regulation of mini excitatory postsynaptic potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syne1 spectrin repeat containing nuclear envelope protein 1 IMP RGD PMID:24191017 RGD:13209020 NCBI chr 1:41,512,146...41,983,382
Ensembl chr 1:41,512,030...41,983,322
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    negative regulation of biological process 5816
      negative regulation of excitatory postsynaptic potential 13
        negative regulation of mini excitatory postsynaptic potential 1
Path 2
Term Annotations click to browse term
  biological_process 20536
    biological regulation 13822
      regulation of biological process 13376
        signaling 7809
          cell-cell signaling 1479
            synaptic signaling 1000
              trans-synaptic signaling 957
                anterograde trans-synaptic signaling 949
                  chemical synaptic transmission 949
                    chemical synaptic transmission, postsynaptic 140
                      excitatory postsynaptic potential 126
                        modulation of excitatory postsynaptic potential 66
                          negative regulation of excitatory postsynaptic potential 13
                            negative regulation of mini excitatory postsynaptic potential 1
paths to the root