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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of heart rate by cardiac conduction
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Accession:GO:0086091 term browser browse the term
Definition:A cardiac conduction process that modulates the frequency or rate of heart contraction.



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regulation of heart rate by cardiac conduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme involved_in IEA
ISS
Ensembl
BHF-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380
JBrowse link
G AKAP9 A-kinase anchoring protein 9 involved_in IMP (PMID:18093912) BHF-UCL PMID:18093912 NCBI chr 7:91,940,862...92,110,673
Ensembl chr 7:91,940,840...92,110,673
JBrowse link
G ANK2 ankyrin 2 involved_in ISS
IMP
(PMID:12571597), (PMID:15178757), (PMID:17242276), (PMID:21859974) BHF-UCL PMID:12571597 PMID:15178757 PMID:17242276 PMID:21859974 GO_REF:0000024 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G BIN1 bridging integrator 1 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288
JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C involved_in IMP (PMID:15454078), (PMID:15863612), (PMID:17224476), (PMID:26253506) BHF-UCL PMID:15454078 PMID:15863612 PMID:17224476 PMID:26253506 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:21131953)
(PMID:12700358)
BHF-UCL
MGI
PMID:12700358 PMID:21131953 NCBI chr 3:53,494,611...53,813,733
Ensembl chr 3:53,328,963...53,813,733
JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr17:50,560,715...50,627,474
Ensembl chr17:50,560,715...50,627,474
JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in IMP (PMID:25527503) BHF-UCL PMID:25527503 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956
JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in IMP (PMID:17224476) BHF-UCL PMID:17224476 NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557
JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta involved_in IC (PMID:22514276) BHF-UCL PMID:22514276 NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927
JBrowse link
G CAV1 caveolin 1 involved_in ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CTNNA3 catenin alpha 3 involved_in IMP (PMID:23136403) BHF-UCL PMID:23136403 NCBI chr10:65,912,523...67,763,594
Ensembl chr10:65,912,457...67,763,637
JBrowse link
G DSC2 desmocollin 2 involved_in IMP (PMID:23863954) BHF-UCL PMID:23863954 NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,545...31,102,600
JBrowse link
G DSG2 desmoglein 2 involved_in IMP (PMID:16505173), (PMID:23381804) BHF-UCL PMID:16505173 PMID:23381804 NCBI chr18:31,498,177...31,549,008
Ensembl chr18:31,497,624...31,551,351
JBrowse link
G DSP desmoplakin involved_in IMP (PMID:12373648) BHF-UCL PMID:12373648 NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,326...7,586,717
JBrowse link
G GJA5 gap junction protein alpha 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 involved_in NAS (PMID:16043489) ComplexPortal PMID:16043489 NCBI chr 5:45,254,948...45,696,380
Ensembl chr 5:45,254,948...45,696,498
JBrowse link
G HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 involved_in NAS (PMID:16043489) ComplexPortal PMID:16043489 NCBI chr 1:155,277,463...155,289,848
Ensembl chr 1:155,277,463...155,289,848
JBrowse link
G HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 involved_in IMP
NAS
(PMID:12750403)
(PMID:20829353)
BHF-UCL
ComplexPortal
PMID:12750403 PMID:20829353 NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
JBrowse link
G ISL1 ISL LIM homeobox 1 acts_upstream_of ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 5:51,383,448...51,394,730
Ensembl chr 5:51,383,448...51,394,730
JBrowse link
G JUP junction plakoglobin involved_in IMP (PMID:17924338) BHF-UCL PMID:17924338 NCBI chr17:41,754,609...41,786,711
Ensembl chr17:41,754,604...41,786,931
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:19343045), (PMID:23264583) BHF-UCL PMID:19343045 PMID:23264583 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788
JBrowse link
G KCND3 potassium voltage-gated channel subfamily D member 3 involved_in IMP (PMID:21349352) BHF-UCL PMID:21349352 NCBI chr 1:111,770,662...111,989,668
Ensembl chr 1:111,770,662...111,989,668
JBrowse link
G KCNE1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in
acts_upstream_of_or_within
IMP
IEA
IBA
(PMID:10400998) BHF-UCL
Ensembl
GO_Central
PMID:10400998 GO_REF:0000033 GO_REF:0000107 NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IMP
IBA
(PMID:10219239) BHF-UCL
GO_Central
PMID:10219239 GO_REF:0000033 NCBI chr21:34,364,006...34,371,381
Ensembl chr21:34,180,729...34,371,381
JBrowse link
G KCNE3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IMP
IBA
(PMID:22987075) BHF-UCL
GO_Central
PMID:22987075 GO_REF:0000033 NCBI chr11:74,454,841...74,467,549
Ensembl chr11:74,454,841...74,467,729
JBrowse link
G KCNE4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:223,052,190...223,055,637
Ensembl chr 2:223,052,190...223,198,399
JBrowse link
G KCNE5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IMP
IBA
(PMID:18313602), (PMID:21493962) BHF-UCL
GO_Central
PMID:18313602 PMID:21493962 GO_REF:0000033 NCBI chr  X:109,623,700...109,625,172
Ensembl chr  X:109,623,700...109,625,172
JBrowse link
G KCNH2 potassium voltage-gated channel subfamily H member 2 involved_in
acts_upstream_of_or_within
IMP
IBA
(PMID:21536673)
(PMID:7889573)
BHF-UCL
GO_Central
MGI
PMID:7889573 PMID:21536673 GO_REF:0000033 NCBI chr 7:150,944,961...150,978,321
Ensembl chr 7:150,944,961...150,978,321
JBrowse link
G KCNH6 potassium voltage-gated channel subfamily H member 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:63,523,358...63,548,992
Ensembl chr17:63,523,334...63,548,977
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in IMP (PMID:15761194) BHF-UCL PMID:15761194 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G KCNJ3 potassium inwardly rectifying channel subfamily J member 3 involved_in IC (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
JBrowse link
G KCNJ5 potassium inwardly rectifying channel subfamily J member 5 involved_in IMP (PMID:20560207) BHF-UCL PMID:20560207 NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IMP (PMID:8528244) BHF-UCL PMID:8528244 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105
JBrowse link
G PKP2 plakophilin 2 involved_in IMP (PMID:17980246), (PMID:22889254) BHF-UCL PMID:17980246 PMID:22889254 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,745...32,896,798
JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 involved_in IMP
IBA
(PMID:19808477) BHF-UCL
GO_Central
PMID:19808477 GO_REF:0000033 NCBI chr19:35,030,470...35,040,449
Ensembl chr19:35,030,470...35,040,449
JBrowse link
G SCN2B sodium voltage-gated channel beta subunit 2 involved_in IMP (PMID:19808477) BHF-UCL PMID:19808477 NCBI chr11:118,162,806...118,176,639
Ensembl chr11:118,162,806...118,176,639
JBrowse link
G SCN3B sodium voltage-gated channel beta subunit 3 involved_in IMP
IBA
(PMID:20042427), (PMID:21051419) BHF-UCL
GO_Central
PMID:20042427 PMID:21051419 GO_REF:0000033 NCBI chr11:123,629,188...123,654,624
Ensembl chr11:123,629,187...123,655,244
JBrowse link
G SCN4B sodium voltage-gated channel beta subunit 4 involved_in IMP (PMID:17592081) BHF-UCL PMID:17592081 NCBI chr11:118,133,377...118,152,823
Ensembl chr11:118,133,377...118,152,888
JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
IMP
ISO
(PMID:21895525)
(PMID:11972032), (PMID:15809371), (PMID:15932895), (PMID:16172272)
BHF-UCL
MGI
PMID:11972032 PMID:15809371 PMID:15932895 PMID:16172272 PMID:21895525 NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,743
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISS
IEA
BHF-UCL
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IMP (PMID:27207958) BHF-UCL PMID:27207958 NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
JBrowse link
G YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon involved_in IC (PMID:11953308) BHF-UCL PMID:11953308 NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27210
    biological regulation 13700
      regulation of biological quality 3695
        regulation of heart rate 134
          regulation of heart rate by cardiac conduction 43
Path 2
Term Annotations click to browse term
  biological_process 27210
    multicellular organismal process 8845
      system process 2960
        circulatory system process 752
          blood circulation 668
            heart contraction 307
              regulation of heart contraction 260
                regulation of heart rate 134
                  regulation of heart rate by cardiac conduction 43
paths to the root