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ONTOLOGY REPORT - ANNOTATIONS

Term:gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling
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Accession:GO:0086078 term browser browse the term
Definition:A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.


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gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 enables ISO
IEA 		(PMID:22247482)
(PMID:26786475)
GO_REF:0000107 		RGD
Ensembl		 PMID:22247482 PMID:26786475 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:187,234,674...187,318,512 		JBrowse link
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  molecular_function 21117
    transporter activity 1285
      transmembrane transporter activity 1168
        passive transmembrane transporter activity 517
          channel activity 517
            wide pore channel activity 39
              gap junction channel activity 23
                gap junction channel activity involved in cell communication by electrical coupling 7
                  gap junction channel activity involved in cardiac conduction electrical coupling 3
                    gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling 1
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