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ONTOLOGY REPORT - ANNOTATIONS
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Term:
gap junction channel activity involved in cardiac conduction electrical coupling
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Accession:
GO:0086075
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Definition:
A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
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Genes (3)
gap junction channel activity involved in cardiac conduction electrical coupling
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
GJA5
gap junction protein alpha 5
enables
IEA
Ensembl
GO_REF:0000107
gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
GJA5
gap junction protein alpha 5
enables
IEA
Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118
gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
GJA5
gap junction protein alpha 5
enables
IEA
Ensembl
GO_REF:0000107
G
GJC1
gap junction protein gamma 1
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr16:61,575,851...61,596,488
Ensembl chr16:61,594,885...61,596,075
G
GJD3
gap junction protein delta 3
enables
IEA
Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr16:65,811,111...65,815,128
Ensembl chr16:65,811,981...65,812,862
gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
GJA5
gap junction protein alpha 5
enables
IEA
Ensembl
GO_REF:0000107
Term paths to the root
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Path 1
Term
Annotations
molecular_function
18124
transporter activity
1196
transmembrane transporter activity
1103
passive transmembrane transporter activity
516
channel activity
516
wide pore channel activity
35
gap junction channel activity
24
gap junction channel activity involved in cell communication by electrical coupling
7
gap junction channel activity involved in cardiac conduction electrical coupling
3
gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling
3
gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling
0
gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling
0
gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling
1
gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling
1