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ONTOLOGY REPORT - ANNOTATIONS


Term:ventricular cardiac muscle cell action potential
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Accession:GO:0086005 term browser browse the term
Definition:An action potential that occurs in a ventricular cardiac muscle cell.



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ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO
IEA
(PMID:17242276)
GO_REF:0000107
RGD
Ensembl
PMID:17242276 GO_REF:0000107 NCBI chr 2:218,052,555...218,628,414
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Cav3 caveolin 3 involved_in IMP PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO
IEA
MGI:2445238 (PMID:9501070)
GO_REF:0000107
RGD
Ensembl
PMID:9501070 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1 like involved_in ISO (PMID:17967977), (PMID:19666841) RGD PMID:17967977 PMID:19666841 NCBI chr 8:123,469,282...123,498,948
Ensembl chr 8:114,588,487...114,620,723
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO
IBA
(PMID:9354802)
GO_REF:0000033
RGD
GO_Central
PMID:9354802 GO_REF:0000033 NCBI chr11:45,066,875...45,080,024
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:10219239)
MGI:3699589 (PMID:18603586)
GO_REF:0000033
RGD
GO_Central
PMID:10219239 PMID:18603586 GO_REF:0000033 NCBI chr11:45,003,468...45,015,942
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:163,936,035...163,942,998
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:87,674,264...87,699,088
Ensembl chr 9:80,247,379...80,250,979
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in ISO
IEA
IBA
(PMID:21493962)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:21493962 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:110,727,234...110,727,849
Ensembl chr  X:105,930,398...105,931,013
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) RGD PMID:21536673 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
(PMID:8528244)
GO_REF:0000107
RGD
Ensembl
PMID:8528244 GO_REF:0000107 NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in IMP PMID:22879586 BHF-UCL PMID:22879586 RGD:8553349 NCBI chr18:60,663,918...60,996,824
Ensembl chr18:58,393,509...58,723,137
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:98,165,974...98,231,916
Ensembl chr11:84,661,783...84,727,730
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17872467) RGD PMID:17872467 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in
acts_upstream_of_or_within
ISO
IEA
IBA
(PMID:20042427)
GO_REF:0000107
MGI:5294639 (PMID:19351516)
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:19351516 PMID:20042427 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:49,527,529...49,550,019
Ensembl chr 8:40,630,455...40,652,868
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA
(PMID:22529811)
GO_REF:0000107
RGD
Ensembl
PMID:22529811 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Snta1 syntrophin, alpha 1 involved_in ISO
IEA
IBA
(PMID:18591664)
GO_REF:0000107
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:18591664 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:163,336,509...163,366,954
Ensembl chr 3:142,876,296...142,906,709
JBrowse link
membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dlg1 discs large MAGUK scaffold protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:25447080)
Ensembl
RGD
PMID:25447080 GO_REF:0000107 NCBI chr11:82,416,853...82,607,797
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 2:195,626,316...195,843,690
Ensembl chr 2:192,937,950...193,155,345
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 involved_in ISO (PMID:9354802) RGD PMID:9354802 NCBI chr11:45,066,875...45,080,024
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO (PMID:10219239) RGD PMID:10219239 NCBI chr11:45,003,468...45,015,942
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 1:163,936,035...163,942,998
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 9:87,674,264...87,699,088
Ensembl chr 9:80,247,379...80,250,979
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr  X:110,727,234...110,727,849
Ensembl chr  X:105,930,398...105,931,013
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:21536673) RGD PMID:21536673 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 involved_in ISO
IEA
(PMID:20558321)
GO_REF:0000107
RGD
Ensembl
PMID:20558321 GO_REF:0000107 NCBI chr 4:177,240,692...177,246,548
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in
acts_upstream_of_or_within
ISO
IEA
IBA
(PMID:8528244)
GO_REF:0000107
MGI:2680653 (PMID:12766260), (PMID:15004216)
GO_REF:0000033
RGD
Ensembl
GO_Central
PMID:8528244 PMID:12766260 PMID:15004216 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:207,721,134...208,054,073
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:54,322,383...54,334,519
Ensembl chr 8:45,425,629...45,437,765
JBrowse link
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 involved_in ISO
IEA
(PMID:22987075)
GO_REF:0000107
RGD
Ensembl
PMID:22987075 GO_REF:0000107 NCBI chr 1:163,936,035...163,942,998
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in ISO (PMID:24836577) RGD PMID:24836577 NCBI chr18:24,282,840...24,341,461
Ensembl chr18:24,009,653...24,067,263
JBrowse link
positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rnf207 ring finger protein 207 acts_upstream_of ISO
IEA
(PMID:25281747)
GO_REF:0000107
RGD
Ensembl
PMID:25281747 GO_REF:0000107 NCBI chr 5:168,098,074...168,112,585
Ensembl chr 5:162,815,357...162,828,375
JBrowse link
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISS
ISO
GO_REF:0000024
(PMID:15454078), (PMID:26253506)
BHF-UCL
RGD
PMID:15454078 PMID:26253506 GO_REF:0000024 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:25017399)
Ensembl
RGD
PMID:25017399 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ctnna3 catenin alpha 3 involved_in ISO (PMID:23136403) RGD PMID:23136403 NCBI chr20:23,613,016...25,198,699
Ensembl chr20:23,623,560...25,199,978
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:25447080)
Ensembl
RGD
PMID:25447080 GO_REF:0000107 NCBI chr11:82,416,853...82,607,797
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Dsc2 desmocollin 2 involved_in ISO
IEA
(PMID:23863954)
GO_REF:0000107
RGD
Ensembl
PMID:23863954 GO_REF:0000107 NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,450,390...11,482,392
JBrowse link
G Dsg2 desmoglein 2 involved_in ISO
IEA
(PMID:16505173), (PMID:23381804)
GO_REF:0000107
RGD
Ensembl
PMID:16505173 PMID:23381804 GO_REF:0000107 NCBI chr18:12,121,287...12,179,590
Ensembl chr18:11,846,183...11,904,156
JBrowse link
G Dsp desmoplakin involved_in ISO
IEA
(PMID:12373648)
GO_REF:0000107
RGD
Ensembl
PMID:12373648 GO_REF:0000107 NCBI chr17:26,829,153...26,877,419
Ensembl chr17:26,623,588...26,671,800
JBrowse link
G Jup junction plakoglobin involved_in ISO
IEA
(PMID:17924338)
GO_REF:0000107
RGD
Ensembl
PMID:17924338 GO_REF:0000107 NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:98,165,974...98,231,916
Ensembl chr11:84,661,783...84,727,730
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17875969) RGD PMID:17875969 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA
(PMID:27207958)
GO_REF:0000107
RGD
Ensembl
PMID:27207958 GO_REF:0000107 NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:95,782,000...95,812,532
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    biological regulation 13841
      regulation of biological quality 3470
        regulation of membrane potential 546
          action potential 198
            cardiac muscle cell action potential 68
              cardiac muscle cell action potential involved in contraction 43
                ventricular cardiac muscle cell action potential 31
                  membrane depolarization during ventricular cardiac muscle cell action potential 0
                  membrane repolarization during ventricular cardiac muscle cell action potential + 12
                  negative regulation of ventricular cardiac muscle cell action potential 1
                  positive regulation of ventricular cardiac muscle cell action potential 0
                  regulation of ventricular cardiac muscle cell action potential + 12
Path 2
Term Annotations click to browse term
  biological_process 20567
    multicellular organismal process 9031
      system process 3586
        circulatory system process 639
          heart process 273
            heart contraction 263
              cardiac muscle contraction 153
                cardiac muscle cell contraction 75
                  cardiac muscle cell action potential involved in contraction 43
                    ventricular cardiac muscle cell action potential 31
                      membrane depolarization during ventricular cardiac muscle cell action potential 0
                      membrane repolarization during ventricular cardiac muscle cell action potential + 12
                      negative regulation of ventricular cardiac muscle cell action potential 1
                      positive regulation of ventricular cardiac muscle cell action potential 0
                      regulation of ventricular cardiac muscle cell action potential + 12
paths to the root