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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cardiac muscle cell contraction
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Accession:GO:0086004 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction.



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regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA RGD PMID:19525381 RGD:2317914 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Adrb1 adrenoceptor beta 1 IMP
IDA
RGD PMID:22216755 PMID:19525381 RGD:6893639, RGD:2317914 NCBI chr 1:265,777,103...265,780,114
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Akap6 A-kinase anchoring protein 6 involved_in IMP PMID:11179196 BHF-UCL PMID:11179196 RGD:8553373 NCBI chr 6:75,919,350...76,359,667
Ensembl chr 6:70,184,175...70,619,738
JBrowse link
G Ank2 ankyrin 2 involved_in ISO UniProtKB:Q8C8R3 (PMID:17242276) RGD PMID:17242276 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 IMP RGD PMID:15629895 RGD:6903236 NCBI chr 2:191,709,311...191,737,414
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 IMP RGD PMID:17442282 RGD:6903343 NCBI chr13:87,261,964...87,286,911
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Casq2 calsequestrin 2 involved_in IMP PMID:17569730 BHF-UCL PMID:17569730 RGD:2314601 NCBI chr 2:192,214,556...192,270,821
Ensembl chr 2:189,525,960...189,582,267
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 IMP RGD PMID:14684371 RGD:9685468 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278
JBrowse link
G Gata4 GATA binding protein 4 IMP RGD PMID:21702924 RGD:7207043 NCBI chr15:41,635,572...41,707,252
Ensembl chr15:37,459,601...37,505,636
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 IMP RGD PMID:22426100 RGD:7247430 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Myh7b myosin heavy chain 7B IMP RGD PMID:32207065 RGD:126925946 NCBI chr 3:164,537,211...164,582,441
Ensembl chr 3:144,098,190...144,122,084
JBrowse link
G Pde4b phosphodiesterase 4B involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pde4d phosphodiesterase 4D involved_in IMP
ISO
(PMID:21670503), (PMID:21903937)
PMID:19801680
RGD PMID:21670503 PMID:21903937 PMID:19801680 PMID:19801680 RGD:7327160, RGD:7327160 NCBI chr 2:41,748,337...43,262,567
Ensembl chr 2:40,019,933...41,525,884
JBrowse link
G Pln phospholamban acts_upstream_of_or_within
involved_in
ISO MGI:2158357 (PMID:8620604)
(PMID:26673394)
RGD PMID:8620604 PMID:26673394 NCBI chr20:33,166,512...33,182,241 JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in
acts_upstream_of_or_within
ISO
ISS
IEA
(PMID:22529811)
MGI:2179753 (PMID:16172272)
GO_REF:0000024
GO_REF:0000107
RGD
BHF-UCL
Ensembl
PMID:16172272 PMID:22529811 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Sri sorcin involved_in ISO (PMID:12754254), (PMID:17130302) RGD PMID:12754254 PMID:17130302 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
JBrowse link
G Stc1 stanniocalcin 1 involved_in ISO (PMID:12663264) RGD PMID:12663264 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 involved_in ISO (PMID:21900893) RGD PMID:21900893 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761
JBrowse link
negative regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31754830 RGD:329403060 NCBI chr13:80,280,595...80,366,939
Ensembl chr13:77,768,468...77,833,951
JBrowse link
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bin1 bridging integrator 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:24836577)
Ensembl
RGD
PMID:24836577 GO_REF:0000107 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263
JBrowse link
positive regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:23954346 RGD:10003031 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
JBrowse link
positive regulation of cardiac muscle cell contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:190,457,198...190,475,410
Ensembl chr 1:181,026,608...181,044,838
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H IMP RGD PMID:19443576 RGD:7205486 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Strit1 small transmembrane regulator of ion transport 1 involved_in ISO (PMID:30299255) RGD PMID:30299255 NCBI chr 2:147,935,219...147,938,083
Ensembl chr 2:147,935,222...147,938,083
JBrowse link
regulation of atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank2 ankyrin 2 involved_in ISO (PMID:12571597) RGD PMID:12571597 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:23348765) RGD PMID:23348765 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17875969) RGD PMID:17875969 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:58,389,925...58,975,142
JBrowse link
regulation of cardiac muscle cell action potential involved in regulation of contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap9 A-kinase anchoring protein 9 involved_in ISO (PMID:18093912) RGD PMID:18093912 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 involved_in IDA PMID:9851937 BHF-UCL PMID:9851937 RGD:10047146 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in IC PMID:12676813 BHF-UCL PMID:12676813 RGD:10047271 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:215,024,004...215,286,178
JBrowse link
G Cav3 caveolin 3 involved_in ISO (PMID:17060380) RGD PMID:17060380 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Fgf13 fibroblast growth factor 13 involved_in ISO (PMID:21817159) RGD PMID:21817159 NCBI chr  X:142,312,381...142,838,581
Ensembl chr  X:137,276,511...137,800,391
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 involved_in ISO
IEA
(PMID:16407510)
GO_REF:0000107
RGD
Ensembl
PMID:16407510 GO_REF:0000107 NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639
JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:21621375) RGD PMID:21621375 NCBI chr10:53,677,467...53,678,880
Ensembl chr10:53,677,467...53,678,840
JBrowse link
regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISS
ISO
GO_REF:0000024
(PMID:15454078), (PMID:26253506)
BHF-UCL
RGD
PMID:15454078 PMID:26253506 GO_REF:0000024 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cav1 caveolin 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:25017399)
Ensembl
RGD
PMID:25017399 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ctnna3 catenin alpha 3 involved_in ISO (PMID:23136403) RGD PMID:23136403 NCBI chr20:23,613,016...25,198,699
Ensembl chr20:23,623,560...25,199,978
JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:25447080)
Ensembl
RGD
PMID:25447080 GO_REF:0000107 NCBI chr11:82,416,853...82,607,797
Ensembl chr11:68,911,883...69,102,689
JBrowse link
G Dsc2 desmocollin 2 involved_in ISO (PMID:23863954) RGD PMID:23863954 NCBI chr18:11,725,466...11,757,591
Ensembl chr18:11,450,390...11,482,392
JBrowse link
G Dsg2 desmoglein 2 involved_in ISO (PMID:16505173), (PMID:23381804) RGD PMID:16505173 PMID:23381804 NCBI chr18:12,121,287...12,179,590
Ensembl chr18:11,846,183...11,904,156
JBrowse link
G Dsp desmoplakin involved_in ISO (PMID:12373648) RGD PMID:12373648 NCBI chr17:26,829,153...26,877,419
Ensembl chr17:26,623,588...26,671,800
JBrowse link
G Jup junction plakoglobin involved_in ISO
IEA
(PMID:17924338)
GO_REF:0000107
RGD
Ensembl
PMID:17924338 GO_REF:0000107 NCBI chr10:85,800,812...85,827,881
Ensembl chr10:85,300,440...85,327,057
JBrowse link
G Pkp2 plakophilin 2 involved_in ISO (PMID:22889254) RGD PMID:22889254 NCBI chr11:98,165,974...98,231,916
Ensembl chr11:84,661,783...84,727,730
JBrowse link
G Ryr2 ryanodine receptor 2 involved_in ISO (PMID:17875969) RGD PMID:17875969 NCBI chr17:63,081,527...63,667,141
Ensembl chr17:58,389,925...58,975,142
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA
(PMID:27207958)
GO_REF:0000107
RGD
Ensembl
PMID:27207958 GO_REF:0000107 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    regulation of biological process 13389
      regulation of cellular process 13025
        regulation of actin filament-based process 426
          regulation of actin filament-based movement 52
            regulation of cardiac muscle cell contraction 42
              negative regulation of cardiac muscle cell contraction + 2
              positive regulation of cardiac muscle cell contraction + 3
              regulation of atrial cardiac muscle cell action potential + 4
              regulation of cardiac muscle cell action potential involved in regulation of contraction 7
              regulation of ventricular cardiac muscle cell action potential + 12
Path 2
Term Annotations click to browse term
  biological_process 20546
    biological regulation 13834
      regulation of biological process 13389
        regulation of multicellular organismal process 3344
          regulation of system process 683
            regulation of muscle system process 283
              regulation of muscle contraction 175
                regulation of striated muscle contraction 99
                  regulation of cardiac muscle contraction 79
                    regulation of cardiac muscle cell contraction 42
                      negative regulation of cardiac muscle cell contraction + 2
                      positive regulation of cardiac muscle cell contraction + 3
                      regulation of atrial cardiac muscle cell action potential + 4
                      regulation of cardiac muscle cell action potential involved in regulation of contraction 7
                      regulation of ventricular cardiac muscle cell action potential + 12
paths to the root