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ONTOLOGY REPORT - ANNOTATIONS

Term:blood coagulation, fibrin clot formation
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Accession:GO:0072378 term browser browse the term
Definition:A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.
Comment:See also the biological process term 'blood coagulation, intrinsic pathway ; GO:0007597'.


show annotations for term's descendants           Sort by:
blood coagulation, fibrin clot formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F13a1 coagulation factor XIII A1 chain involved_in ISS
ISO
IBA
IEA		 GO_REF:0000024
MGI:5645817 (PMID:18224415)
GO_REF:0000033
GO_REF:0000107
(PMID:27363989)		 UniProt
RGD
GO_Central
Ensembl		 PMID:18224415 PMID:27363989 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr17:28,021,197...28,197,960
Ensembl chr17:27,815,702...27,992,700 		JBrowse link
G F13b coagulation factor XIII B chain involved_in ISO
IEA		 (PMID:27363989)
GO_REF:0000107		 RGD
Ensembl		 PMID:27363989 GO_REF:0000107 NCBI chr13:51,130,908...51,156,383
Ensembl chr13:51,130,920...51,156,381 		JBrowse link
G Fbln1 fibulin 1 involved_in ISO
IEA		 (PMID:7642629)
GO_REF:0000107		 RGD
Ensembl		 PMID:7642629 GO_REF:0000107 NCBI chr 7:118,190,347...118,269,965
Ensembl chr 7:116,310,582...116,390,075 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO
IEA
IBA		 (PMID:16846481)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:16846481 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:11001902), (PMID:16846481) RGD PMID:11001902 PMID:16846481 NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Itgb3 integrin subunit beta 3 acts_upstream_of_or_within ISO
IEA		 MGI:2175913 (PMID:28576878)
GO_REF:0000107		 RGD
Ensembl		 PMID:28576878 GO_REF:0000107 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 acts_upstream_of_or_within ISO MGI:5636896 (PMID:28576878) RGD PMID:28576878 NCBI chr 4:78,134,144...78,153,191
Ensembl chr 4:76,803,198...76,822,107 		JBrowse link
blood coagulation, common pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fga fibrinogen alpha chain involved_in ISO
IBA		 (PMID:12706644)
GO_REF:0000033
(PMID:10891444)		 RGD
GO_Central		 PMID:10891444 PMID:12706644 GO_REF:0000033 NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
blood coagulation, extrinsic pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F5 coagulation factor V TAS RGD PMID:15172885 RGD:1601118 NCBI chr13:79,046,657...79,116,247
Ensembl chr13:76,513,255...76,582,317 		JBrowse link
blood coagulation, intrinsic pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO (PMID:4052628) RGD PMID:4052628 NCBI chr10:93,841,992...93,855,897
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G F8 coagulation factor VIII involved_in IMP
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:2513867 GO_REF:0000033, RGD:1582368 NCBI chr18:155,237...187,186
Ensembl chr18:140,955...171,857 		JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:10501658) RGD PMID:10501658 NCBI chr10:55,831,901...55,856,729
Ensembl chr10:55,352,899...55,356,774 		JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta involved_in ISO (PMID:10501658) RGD PMID:10501658 NCBI chr11:95,882,561...95,883,738
Ensembl chr11:82,378,199...82,379,392 		JBrowse link
G Gp5 glycoprotein V (platelet) involved_in ISO
IEA		 (PMID:10501658)
GO_REF:0000107		 RGD
Ensembl		 PMID:10501658 GO_REF:0000107 NCBI chr11:83,948,507...83,952,362
Ensembl chr11:70,443,613...70,446,705 		JBrowse link
G Gp9 glycoprotein IX (platelet) involved_in ISO
IEA		 (PMID:10501658)
GO_REF:0000107		 RGD
Ensembl		 PMID:10501658 GO_REF:0000107 NCBI chr 4:120,235,500...120,237,110
Ensembl chr 4:120,235,421...120,237,110 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    multicellular organismal process 9017
      coagulation 217
        blood coagulation 209
          blood coagulation, fibrin clot formation 15
            blood coagulation, common pathway + 1
            blood coagulation, extrinsic pathway + 1
            blood coagulation, intrinsic pathway + 6
Path 2
Term Annotations click to browse term
  biological_process 20558
    cellular process 19550
      metabolic process 12180
        biosynthetic process 8654
          macromolecule biosynthetic process 7646
            gene expression 7208
              protein maturation 644
                protein activation cascade 20
                  blood coagulation, fibrin clot formation 15
                    blood coagulation, common pathway + 1
                    blood coagulation, extrinsic pathway + 1
                    blood coagulation, intrinsic pathway + 6
paths to the root