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ONTOLOGY REPORT - ANNOTATIONS


Term:cellular response to xenobiotic stimulus
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Accession:GO:0071466 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms:related_synonym: cellular response to drug
 alt_id: GO:0035690



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cellular response to xenobiotic stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 IEP pitavastatin, clofibrate, GW 6471 RGD PMID:21554872 RGD:21408554 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 IEP RGD PMID:27090119 RGD:15090804 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 IEP RGD PMID:27090119 RGD:15090804 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:24037327)
GO_REF:0000107
RGD
Ensembl
PMID:24037327 GO_REF:0000107 NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
JBrowse link
G Acer2 alkaline ceramidase 2 involved_in ISO (PMID:20628055) RGD PMID:20628055 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing involved_in ISS
ISO
GO_REF:0000024
(PMID:19109165)
UniProt
RGD
PMID:19109165 GO_REF:0000024 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adm adrenomedullin IEP RGD PMID:12193565 RGD:628358 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Adss1 adenylosuccinate synthase 1 IEP cyclosporin A RGD PMID:10636885 RGD:5135512 NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998
JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP losartan, metformin RGD PMID:22467055 RGD:7245559 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Aim2 absent in melanoma 2 acts_upstream_of_or_within ISO (PMID:19158679) RGD PMID:19158679 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975
JBrowse link
G Akap5 A-kinase anchoring protein 5 acts_upstream_of_or_within ISO MGI:3766311 (PMID:23259949) RGD PMID:23259949 NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
JBrowse link
G Ankrd1 ankyrin repeat domain 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:17239933)
Ensembl
RGD
PMID:17239933 GO_REF:0000107 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Asic2 acid sensing ion channel subunit 2 IDA amiloride RGD PMID:12736332 RGD:1298620 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
JBrowse link
G Bcl2l1 Bcl2-like 1 IEP carboplatin RGD PMID:18483861 RGD:2293312 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479
JBrowse link
G Blm BLM RecQ like helicase acts_upstream_of_or_within ISO MGI:2448558 (PMID:25520194) RGD PMID:25520194 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within ISO (PMID:22628551) RGD PMID:22628551 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IEP N-phosphonoacetyl-L-aspartate RGD PMID:8548770 RGD:5132280 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP nifedipine RGD PMID:16331110 RGD:2298662 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:24486487)
Ensembl
RGD
PMID:24486487 GO_REF:0000107 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Cd69 Cd69 molecule involved_in ISO (PMID:19109165) RGD PMID:19109165 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Cdh13 cadherin 13 IEP RGD PMID:12559965 RGD:632357 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha IEP rosiglitazone RGD PMID:1377818 RGD:69946 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cers1 ceramide synthase 1 involved_in ISO (PMID:19800881) RGD PMID:19800881 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
JBrowse link
G Chek2 checkpoint kinase 2 IEP alpha-difluoromethylornithine RGD PMID:21745814 RGD:10401653 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Crhbp corticotropin releasing hormone binding protein involved_in ISS
ISO
GO_REF:0000024
(PMID:15976007)
UniProt
RGD
PMID:15976007 GO_REF:0000024 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO (PMID:29581031) RGD PMID:29581031 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IEP RGD PMID:20613717 RGD:11352688 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Ddc dopa decarboxylase IEP L-DOPA RGD PMID:18602388 RGD:5129085 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Dpep1 dipeptidase 1 involved_in ISO
ISS
(PMID:20435919)
GO_REF:0000024
RGD
UniProt
PMID:20435919 GO_REF:0000024 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G E2f1 E2F transcription factor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:24726645)
Ensembl
RGD
PMID:24726645 GO_REF:0000107 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
JBrowse link
G Edn1 endothelin 1 IEP cyclosporine RGD PMID:8129032 RGD:8662286 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 IEP cilostazol RGD PMID:21390260 RGD:10401124 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 IEP flutamide RGD PMID:24793618 RGD:10045571 NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079
JBrowse link
G Egfr epidermal growth factor receptor IEP vorinostat
NADPH oxidase inhibitors VAS2870, apocynin
RGD PMID:21389970 PMID:21276422 RGD:5131459, RGD:5131479 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 IEP imipramine RGD PMID:21354245 RGD:5131879 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 IEP amitriptyline RGD PMID:22880885 RGD:9588218 NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
JBrowse link
G Ep300 E1A binding protein p300 IEP valproic acid RGD PMID:20888352 RGD:7364728 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Esr2 estrogen receptor 2 IEP tamoxifen RGD PMID:19279558 RGD:7364795 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fancb FA complementation group B acts_upstream_of_or_within ISO MGI:1328362|MGI:2156841 (PMID:25520194) RGD PMID:25520194 NCBI chr  X:29,403,771...29,420,484
Ensembl chr  X:29,403,771...29,420,192
JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISO
IEA
ISS
(PMID:16442285), (PMID:18650089)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:16442285 PMID:18650089 GO_REF:0000024 GO_REF:0000107 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fgf21 fibroblast growth factor 21 IEP RGD PMID:23118742 RGD:10401886 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Gas6 growth arrest specific 6 involved_in ISO
IDA
(PMID:16359517)
PMID:18374201
RGD PMID:16359517 PMID:18374201 RGD:8554638 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO
ISS
IEA
(PMID:17761367)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:17761367 GO_REF:0000024 GO_REF:0000107 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gstm1 glutathione S-transferase mu 1 acts_upstream_of_or_within ISO (PMID:8512323) RGD PMID:8512323 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm3 glutathione S-transferase mu 3 acts_upstream_of_or_within ISO (PMID:8512323) RGD PMID:8512323 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP isoproterenol RGD PMID:20193759 RGD:9068889 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hsf1 heat shock transcription factor 1 IEP amlodipine besylate, amlodipine camsylate RGD PMID:21988238 RGD:10402816 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IEP RGD PMID:18757512 RGD:11354916 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B involved_in ISO
ISS
(PMID:1315531)
GO_REF:0000024
RGD
UniProt
PMID:1315531 GO_REF:0000024 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Il1b interleukin 1 beta acts_upstream_of_or_within ISO (PMID:19158679) RGD PMID:19158679 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Itgb3 integrin subunit beta 3 IEP RGD PMID:12242040 RGD:4999478 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 IEP fluoxetine RGD PMID:11543764 RGD:9685702 NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 IEP RGD PMID:17293496 RGD:7247436 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in ISO
IDA
(PMID:10219239) RGD PMID:10219239 PMID:10219239 RGD:633041 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:7604285) RGD PMID:7604285 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO
IEA
(PMID:9108097)
GO_REF:0000107
RGD
Ensembl
PMID:9108097 GO_REF:0000107 NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO (PMID:23259949) RGD PMID:23259949 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:23259949)
Ensembl
RGD
PMID:23259949 GO_REF:0000107 NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653
JBrowse link
G Mcm7 minichromosome maintenance complex component 7 acts_upstream_of_or_within ISO (PMID:24726645) RGD PMID:24726645 NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO
GO_REF:0000024
(PMID:16775627)
UniProt
RGD
PMID:16775627 GO_REF:0000024 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mmp1 matrix metallopeptidase 1 IEP ibuprophen RGD PMID:19847888 RGD:7207385 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor involved_in IEP
ISO
emodin
(PMID:19179467)
(PMID:17873522), (PMID:19179467)
RGD PMID:17873522 PMID:19179467 PMID:17886230 RGD:10059617 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mylk myosin light chain kinase acts_upstream_of_or_within ISO (PMID:18524939) RGD PMID:18524939 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 acts_upstream_of_or_within ISO MGI:2386080 (PMID:24486487) RGD PMID:24486487 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in ISO (PMID:18757402) RGD PMID:18757402 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 IEP isoproterenol RGD PMID:11082283 RGD:2299080 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
JBrowse link
G Nos2 nitric oxide synthase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:24486487)
Ensembl
RGD
PMID:24486487 GO_REF:0000107 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 IDA
IEP
RGD PMID:29235094 PMID:27090119 RGD:15042872, RGD:15090804 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Pax6 paired box 6 IEP pramipexole RGD PMID:19619535 RGD:8552332 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
JBrowse link
G Pcna proliferating cell nuclear antigen acts_upstream_of_or_within ISO (PMID:24726645) RGD PMID:24726645 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pde2a phosphodiesterase 2A involved_in ISO (PMID:14687666) RGD PMID:14687666 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
JBrowse link
G Pde4a phosphodiesterase 4A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:11267656)
Ensembl
RGD
PMID:11267656 GO_REF:0000107 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961
JBrowse link
G Pde4b phosphodiesterase 4B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:11267656)
Ensembl
RGD
PMID:11267656 GO_REF:0000107 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase IEP malotilate RGD PMID:3012070 RGD:5135033 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144
JBrowse link
G Ppm1e protein phosphatase, Mg2+/Mn2+ dependent, 1E involved_in ISO (PMID:20801214) RGD PMID:20801214 NCBI chr10:72,051,643...72,187,439
Ensembl chr10:72,055,208...72,187,282
JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F involved_in ISO
ISS
(PMID:20801214)
GO_REF:0000024
RGD
UniProt
PMID:20801214 GO_REF:0000024 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:18524939)
Ensembl
RGD
PMID:18524939 GO_REF:0000107 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
G Ppp1r14a protein phosphatase 1, regulatory (inhibitor) subunit 14A acts_upstream_of_or_within ISO (PMID:18524939) RGD PMID:18524939 NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IEP methapyrilene RGD PMID:23274394 RGD:9999168 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B IEP haloperidol RGD PMID:16844384 RGD:10043796 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 IEP RGD PMID:27090119 RGD:15090804 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2448467 (PMID:23918774)
Ensembl
RGD
PMID:23918774 GO_REF:0000107 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prnp prion protein acts_upstream_of_or_within ISO (PMID:16254249) RGD PMID:16254249 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Qdpr quinoid dihydropteridine reductase IEP theophylline RGD PMID:2484967 RGD:5128599 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
JBrowse link
G Ranbp1 RAN binding protein 1 IEP phenylephrine RGD PMID:25341891 RGD:9835001 NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family IDA rolipram RGD PMID:10908723 RGD:10003157 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family IDA rolipram RGD PMID:10908723 RGD:10003157 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370
JBrowse link
G Rap2a RAP2A, member of RAS oncogene family involved_in ISO (PMID:22797597) RGD PMID:22797597 NCBI chr15:97,596,848...97,597,338
Ensembl chr15:97,596,020...97,624,138
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 IEP roflumilast RGD PMID:18276108 RGD:9835371 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1931018 (PMID:24726645)
Ensembl
RGD
PMID:24726645 GO_REF:0000107 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
JBrowse link
G Rbm22 RNA binding motif protein 22 involved_in ISO
ISS
(PMID:21122810)
GO_REF:0000024
RGD
UniProt
PMID:21122810 GO_REF:0000024 NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569
JBrowse link
G Recql5 RecQ like helicase 5 acts_upstream_of_or_within ISO MGI:2448558 (PMID:25520194) RGD PMID:25520194 NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652
JBrowse link
G Reg3b regenerating family member 3 beta IEP troglitazone RGD PMID:11854617 RGD:9831383 NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
JBrowse link
G Ren renin IEP secretagogue C4880 RGD PMID:21963836 RGD:6892652 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
ISS
IEA
(PMID:20564196)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:20564196 GO_REF:0000024 GO_REF:0000107 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
G Rnf149 ring finger protein 149 acts_upstream_of_or_within ISO (PMID:22628551) RGD PMID:22628551 NCBI chr 9:41,826,825...41,854,381
Ensembl chr 9:41,830,233...41,854,279
JBrowse link
G Serpine1 serpin family E member 1 IDA valproic acid RGD PMID:23378038 RGD:8547945 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Slamf8 SLAM family member 8 acts_upstream_of_or_within ISO MGI:5442794 (PMID:22593622) RGD PMID:22593622 NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211
JBrowse link
G Slc10a1 solute carrier family 10 member 1 IEP RGD PMID:27090119 RGD:15090804 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc18a2 solute carrier family 18 member A2 IMP 1-methyl-4-phenylpyridinium, acriflavine RGD PMID:20007701 RGD:5130957 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 IEP RGD PMID:27090119 RGD:15090804 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Sox10 SRY-box transcription factor 10 IEP arecaidine RGD PMID:24403178 RGD:12879828 NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544
JBrowse link
G Tfrc transferrin receptor acts_upstream_of_or_within ISO (PMID:16254249) RGD PMID:16254249 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Th tyrosine hydroxylase IEP L-DOPA RGD PMID:18602388 RGD:5129085 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tlr3 toll-like receptor 3 IEP methimazole derivative C10 RGD PMID:15661832 RGD:5128798 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tp53 tumor protein p53 involved_in ISO
IEA
(PMID:20810912)
GO_REF:0000107
RGD
Ensembl
PMID:20810912 GO_REF:0000107 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Txn1 thioredoxin 1 IEP dipyridamole RGD PMID:20453393 RGD:5133719 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 involved_in ISO (PMID:23064229) RGD PMID:23064229 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IEP RGD PMID:8632018 RGD:10769355 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Umps uridine monophosphate synthetase IEP pyrazofurin RGD PMID:6134725 RGD:5132277 NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903
JBrowse link
G Vegfa vascular endothelial growth factor A IEP RGD PMID:22326847 RGD:7421605 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Wdr35 WD repeat domain 35 IEP RGD PMID:18472094 RGD:11553927 NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 involved_in ISO (PMID:31496133) RGD PMID:31496133 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
JBrowse link
4-chlorobiphenyl metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
arsonoacetate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G As3mt arsenite methyltransferase involved_in IDA
IBA
ISO
IEA
PMID:11790780
GO_REF:0000033
(PMID:25997655)
GO_REF:0000107
GO_Central
RGD
Ensembl
PMID:25997655 PMID:11790780 GO_REF:0000033 GO_REF:0000107, RGD:625365 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872
JBrowse link
G N6amt1 N-6 adenine-specific DNA methyltransferase 1 involved_in ISO (PMID:25997655) RGD PMID:25997655 NCBI chr11:26,584,750...26,597,790
Ensembl chr11:26,584,724...26,608,248
JBrowse link
biphenyl catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 IDA RGD PMID:16006569 RGD:1600442 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
carbon tetrachloride metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnaja2 DnaJ heat shock protein family (Hsp40) member A2 IEP RGD PMID:15270078 RGD:4891447 NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
JBrowse link
dibenzo-p-dioxin catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA
IMP
2,3,7,8-tetrachlorodibenzo-p-dioxin RGD PMID:15812643 PMID:12914780 RGD:2306662, RGD:2306673 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
dichloromethane metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstt1 glutathione S-transferase theta 1 IDA RGD PMID:11453994 RGD:7794854 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
insecticide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IDA Deltamethrin (pyrethroid) RGD PMID:16169030 RGD:2306660 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
nitroglycerin metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh2 aldehyde dehydrogenase 2 family member involved_in ISS
ISO
GO_REF:0000024
(PMID:19506075)
UniProt
RGD
PMID:19506075 GO_REF:0000024 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 IEP RGD PMID:16520233 RGD:401900296 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
phenylacetate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaa1a acetyl-CoA acyltransferase 1A involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Pon3 paraoxonase 3 IDA RGD PMID:12946270 RGD:1303961 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855
JBrowse link
positive regulation of cellular response to drug term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sufu SUFU negative regulator of hedgehog signaling IEP RGD PMID:30790292 RGD:150573813 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
JBrowse link
propylene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO (PMID:21795692) RGD PMID:21795692 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
regulation of cellular response to drug term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 IDA RGD PMID:15198509 RGD:2303058 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Pon3 paraoxonase 3 involved_in ISO
IEA
(PMID:15772423)
GO_REF:0000107
RGD
Ensembl
PMID:15772423 GO_REF:0000107 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855
JBrowse link
thiocyanate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lpo lactoperoxidase involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr10:72,606,950...72,626,220
Ensembl chr10:72,606,944...72,626,535
JBrowse link
trichloroethylene metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 IDA RGD PMID:15987776 RGD:2301693 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
xenobiotic catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 IMP RGD PMID:18088505 RGD:14700808 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 IDA RGD PMID:10725307 RGD:2312871 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Cryz crystallin zeta involved_in ISO
IEA
ISS
(PMID:17497241)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:17497241 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 involved_in ISO
IEA
(PMID:18356043), (PMID:18619574)
GO_REF:0000107
RGD
Ensembl
PMID:18356043 PMID:18619574 GO_REF:0000107 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 involved_in ISO (PMID:19029318) RGD PMID:19029318 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 involved_in ISO
IDA
(PMID:19029318) RGD PMID:19029318 PMID:16039681 RGD:401965478 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:18619574) RGD PMID:18619574
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 involved_in
NOT|involved_in
ISO (PMID:15051713)
(PMID:18838503)
RGD PMID:15051713 PMID:18838503 NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in ISO (PMID:15039299), (PMID:15327587), (PMID:18356043), (PMID:18619574) RGD PMID:15039299 PMID:15327587 PMID:18356043 PMID:18619574 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 involved_in ISO (PMID:15039299) RGD PMID:15039299 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 acts_upstream_of_or_within ISO MGI:5487815 (PMID:19262426) RGD PMID:19262426 NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 involved_in IDA PMID:17112229 CAFA PMID:17112229 RGD:12793043 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gstm1 glutathione S-transferase mu 1 involved_in IDA
ISO
PMID:17112229
(PMID:8373352)
RGD PMID:8373352 PMID:17112229 RGD:12793043 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 involved_in IDA
ISO
PMID:17112229
(PMID:16549767), (PMID:2034681), (PMID:8373352)
RGD PMID:2034681 PMID:8373352 PMID:16549767 PMID:17112229 RGD:12793043 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gstm4 glutathione S-transferase mu 4 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:8373352)
(PMID:12069689)
GO_REF:0000107
RGD
Ensembl
PMID:8373352 PMID:12069689 GO_REF:0000107 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 involved_in ISO (PMID:8373352) RGD PMID:8373352 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203
JBrowse link
G Gsto1 glutathione S-transferase omega 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:12928150)
UniProt
Ensembl
RGD
PMID:12928150 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Nos1 nitric oxide synthase 1 acts_upstream_of_or_within ISO MGI:1857227 (PMID:11158245) RGD PMID:11158245 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 involved_in ISO
ISS
(PMID:12578355)
GO_REF:0000024
RGD
UniProt
PMID:12578355 GO_REF:0000024 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nudt15 nudix hydrolase 15 involved_in ISO (PMID:26878724) RGD PMID:26878724 NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363
JBrowse link
xenobiotic glucuronidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 involved_in IDA
ISO
(PMID:15472229), (PMID:18719240), (PMID:19830808), (PMID:20056724) RGD PMID:15472229 PMID:18719240 PMID:19830808 PMID:20056724 PMID:8806713 RGD:10769352 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 involved_in ISO (PMID:20056724) RGD PMID:20056724 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a3 UDP glycosyltransferase 1 family, polypeptide A3 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in ISO (PMID:20056724) RGD PMID:20056724 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b34l1 UDP glucuronosyltransferase 2 family, polypeptide B34 like 1 involved_in ISO (PMID:11300766) RGD PMID:11300766 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
xenobiotic metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 involved_in ISO
IEA
ISS
IMP
(PMID:18245269)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:18245269 PMID:18245269 GO_REF:0000024 GO_REF:0000107, RGD:30309924 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Ahr aryl hydrocarbon receptor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
JBrowse link
G Aip aryl-hydrocarbon receptor-interacting protein acts_upstream_of_or_within ISO PR:P30561 (PMID:9083006) RGD PMID:9083006 NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122
JBrowse link
G Aox1 aldehyde oxidase 1 involved_in TAS
ISO
IEA
ISS
(PMID:23462233)
GO_REF:0000107
GO_REF:0000024
(PMID:20444863), (PMID:22031625), (PMID:22522748), (PMID:23857892)
RGD
Ensembl
UniProt
PMID:20444863 PMID:22031625 PMID:22522748 PMID:23462233 PMID:23857892 More... GO_REF:0000024 GO_REF:0000107, RGD:730052 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Aox2 aldehyde oxidase 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:59,828,403...59,916,175
Ensembl chr 9:59,828,084...59,916,146
JBrowse link
G Aox3 aldehyde oxidase 3 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:59,664,784...59,749,701
Ensembl chr 9:59,664,809...59,818,169
JBrowse link
G Aox4 aldehyde oxidase 4 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:59,761,238...59,818,169
Ensembl chr 9:59,664,809...59,818,169
JBrowse link
G Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase IMP RGD PMID:18515330 RGD:2303526 NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861
JBrowse link
G Cbr1 carbonyl reductase 1 involved_in ISO
ISS
(PMID:18449627)
GO_REF:0000024
RGD
UniProt
PMID:18449627 GO_REF:0000024 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 involved_in ISO (PMID:19219744) RGD PMID:19219744 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 acts_upstream_of_or_within
involved_in
IDA
ISO
MGI:2182351 (PMID:8643688)
(PMID:15327587), (PMID:19219744)
RGD PMID:8643688 PMID:15327587 PMID:19219744 PMID:6772643 RGD:151347456 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 involved_in IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:22888116)
Ensembl
UniProt
RGD
PMID:22888116 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 involved_in ISO (PMID:26937021) RGD PMID:26937021 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:26937021)
UniProt
RGD
PMID:26937021 GO_REF:0000024 NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
JBrowse link
G Cyp2ab1 cytochrome P450, family 2, subfamily ab, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:80,582,633...80,591,217
Ensembl chr11:80,582,938...80,590,873
JBrowse link
G Cyp2ac1 cytochrome P450, family 2, subfamily ac, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:20,035,823...20,058,570
Ensembl chr 9:20,033,780...20,058,837
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 involved_in IDA
IBA
GO_REF:0000033 GO_Central
RGD
PMID:9425052 GO_REF:0000033, RGD:2301461 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,007,609...82,019,409
Ensembl chr 1:82,007,609...82,080,480
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 involved_in TAS
IBA
IDA
GO_REF:0000033 GO_Central
RGD
PMID:11996101 PMID:9425052 GO_REF:0000033, RGD:1298848, RGD:2301461 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b21 cytochrome P450, family 2, subfamily b, polypeptide 21 involved_in NAS
IBA
GO_REF:0000033 GO_Central
RGD
PMID:11159754 GO_REF:0000033, RGD:1299648 NCBI chr 1:81,886,097...81,915,066
Ensembl chr 1:81,886,098...81,915,066
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 involved_in ISO
IBA
(PMID:18356043), (PMID:19651758), (PMID:20061448)
GO_REF:0000033
RGD
GO_Central
PMID:18356043 PMID:19651758 PMID:20061448 GO_REF:0000033 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 involved_in TAS
IBA
GO_REF:0000033 GO_Central
RGD
PMID:8611037 GO_REF:0000033, RGD:1298853 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
JBrowse link
G Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738
JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:242,889,218...242,913,869
Ensembl chr 1:242,889,224...242,913,858
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:237,009,411...237,054,555
Ensembl chr 1:237,009,368...237,054,564
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 involved_in NAS
IBA
ISO
GO_REF:0000033
(PMID:19219744), (PMID:19651758)
GO_Central
RGD
PMID:19219744 PMID:19651758 PMID:12965116 GO_REF:0000033, RGD:728216 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c6-ps2 cytochrome P450, family 2, subfamily C, polypeptide 6, pseudogene 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:238,352,261...238,391,716
Ensembl chr 1:238,352,131...238,504,300
JBrowse link
G Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 involved_in ISO (PMID:19651758) RGD PMID:19651758
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 involved_in
NOT|involved_in
ISO
IBA
(PMID:15051713)
GO_REF:0000033
(PMID:18838503)
RGD
GO_Central
PMID:15051713 PMID:18838503 GO_REF:0000033 NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 involved_in IDA
IBA
ISO
GO_REF:0000033
(PMID:18356043), (PMID:19219744)
GO_Central
RGD
PMID:18356043 PMID:19219744 PMID:8910433 GO_REF:0000033, RGD:728177 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2d5 cytochrome P450, family 2, subfamily d, polypeptide 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,899,905...113,904,458
Ensembl chr 7:113,899,890...113,904,495
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 involved_in NAS
IBA
IEA
ISO
IMP
GO_REF:0000033
GO_REF:0000107
(PMID:18356043), (PMID:19219744)
GO_Central
Ensembl
RGD
PMID:18356043 PMID:19219744 PMID:12220509 PMID:21187827 GO_REF:0000033 GO_REF:0000107, RGD:625597, RGD:4892233 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp2g1 cytochrome P450, family 2, subfamily g, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828
JBrowse link
G Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:110,960,319...110,995,220
Ensembl chr 5:110,960,317...110,995,115
JBrowse link
G Cyp2j16 cytochrome P450, family 2, subfamily j, polypeptide 16 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:111,089,438...111,138,918
Ensembl chr 5:111,088,674...111,139,013
JBrowse link
G Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
JBrowse link
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 involved_in ISO
IBA
(PMID:16551781)
GO_REF:0000033
RGD
GO_Central
PMID:16551781 GO_REF:0000033 NCBI chr12:15,291,552...15,296,421
Ensembl chr12:15,291,704...15,296,421
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 involved_in IDA
ISO
(PMID:19219744) RGD PMID:19219744 PMID:12971802 RGD:5129544 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 IDA RGD PMID:12971802 RGD:5129544 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 involved_in ISO (PMID:20667828) RGD PMID:20667828 NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 acts_upstream_of_or_within ISO MGI:5487815 (PMID:19262426) RGD PMID:19262426 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:11744609)
Ensembl
RGD
PMID:11744609 GO_REF:0000107 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 IDA RGD PMID:17173378 RGD:1626480 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 involved_in ISO
IEA
ISS
(PMID:20947616), (PMID:28783300)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20947616 PMID:28783300 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta3l1 glutathione S-transferase alpha 3 like 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,619,691...23,628,517
Ensembl chr 9:23,620,010...23,632,333
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 involved_in ISO
IBA
(PMID:10329152)
GO_REF:0000033
RGD
GO_Central
PMID:10329152 GO_REF:0000033 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:23,743,262...23,806,260
Ensembl chr 9:23,744,288...23,801,131
JBrowse link
G Gstm2 glutathione S-transferase mu 2 TAS RGD PMID:3020050 RGD:730286 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
JBrowse link
G Gsto2 glutathione S-transferase omega 2 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:15970797)
UniProt
Ensembl
RGD
PMID:15970797 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
JBrowse link
G Gstp1 glutathione S-transferase pi 1 involved_in TAS
ISO
(PMID:1540159) RGD PMID:1540159 PMID:3029128 RGD:728729 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Guk1 guanylate kinase 1 involved_in ISO (PMID:6306664) RGD PMID:6306664 NCBI chr10:43,971,514...43,988,658
Ensembl chr10:43,971,509...43,980,107
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha involved_in
acts_upstream_of_positive_effect
IEA
ISO
GO_REF:0000107
(PMID:17827783)
Ensembl
RGD
PMID:17827783 GO_REF:0000107 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G LOC103691092 cytochrome P450 2B9-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:81,791,776...81,810,482
Ensembl chr 1:81,784,649...81,810,482
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 acts_upstream_of_or_within ISO MGI:3629327 (PMID:15840715) RGD PMID:15840715 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 involved_in ISO
ISS
(PMID:12578355)
GO_REF:0000024
RGD
UniProt
PMID:12578355 GO_REF:0000024 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Rora RAR-related orphan receptor A involved_in ISO UniProtKB:P51450 (PMID:17666523) RGD PMID:17666523 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
JBrowse link
G Rorc RAR-related orphan receptor C involved_in ISO UniProtKB:P51448 (PMID:17666523) RGD PMID:17666523 NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 involved_in TAS
ISO
IDA
(PMID:12471039), (PMID:20056724)
nitrofen
RGD PMID:12471039 PMID:20056724 PMID:1513323 PMID:6959650 PMID:14754874 RGD:730083, RGD:2301075, RGD:2301063 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 involved_in ISO (PMID:20056724) RGD PMID:20056724 NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 involved_in ISO (PMID:28992322) RGD PMID:28992322 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 involved_in IDA
ISS
ISO
GO_REF:0000024
(PMID:7854148)
UniProt
RGD
PMID:7854148 PMID:16099924 GO_REF:0000024, RGD:5129555 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Tpmt thiopurine S-methyltransferase involved_in ISO
IEA
(PMID:18484748), (PMID:657528)
GO_REF:0000107
RGD
Ensembl
PMID:657528 PMID:18484748 GO_REF:0000107 NCBI chr17:17,644,088...17,662,709
Ensembl chr17:17,644,173...17,662,709
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 involved_in ISO (PMID:3141926) RGD PMID:3141926 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in
NOT|involved_in
ISO (PMID:1910331)
(PMID:20610558)
RGD PMID:1910331 PMID:20610558 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 TAS RGD PMID:3084479 RGD:1299519 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 involved_in ISO (PMID:21127708) RGD PMID:21127708 NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    response to stimulus 10795
      response to chemical 5901
        response to xenobiotic stimulus 736
          cellular response to xenobiotic stimulus 223
            negative regulation of cellular response to drug 0
            positive regulation of cellular response to drug 1
            regulation of cellular response to drug + 3
            xenobiotic metabolic process + 113
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