ONTOLOGY REPORT - ANNOTATIONS
Term: cellular response to xenobiotic stimulus
Accession: GO:0071466
browse the term
Definition: Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.
Synonyms: related_synonym: cellular response to drug
alt_id: GO:0035690
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Abca1
ATP binding cassette subfamily A member 1
IEP
pitavastatin, clofibrate, GW 6471
RGD
PMID:21554872
RGD:21408554
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abcb11
ATP binding cassette subfamily B member 11
IEP
RGD
PMID:27090119
RGD:15090804
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcc2
ATP binding cassette subfamily C member 2
IEP
RGD
PMID:27090119
RGD:15090804
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc9
ATP binding cassette subfamily C member 9
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:24037327) GO_REF:0000107
RGD Ensembl
PMID:24037327
GO_REF:0000107
NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
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Acer2
alkaline ceramidase 2
involved_in
ISO
(PMID:20628055)
RGD
PMID:20628055
NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
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Adipoq
adiponectin, C1Q and collagen domain containing
involved_in
ISS ISO
GO_REF:0000024 (PMID:19109165)
UniProt RGD
PMID:19109165
GO_REF:0000024
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Adm
adrenomedullin
IEP
RGD
PMID:12193565
RGD:628358
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adss1
adenylosuccinate synthase 1
IEP
cyclosporin A
RGD
PMID:10636885
RGD:5135512
NCBI chr 6:131,679,795...131,702,012
Ensembl chr 6:131,679,701...131,701,998
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Ager
advanced glycosylation end product-specific receptor
IEP
losartan, metformin
RGD
PMID:22467055
RGD:7245559
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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Aim2
absent in melanoma 2
acts_upstream_of_or_within
ISO
(PMID:19158679)
RGD
PMID:19158679
NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975
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Akap5
A-kinase anchoring protein 5
acts_upstream_of_or_within
ISO
MGI:3766311 (PMID:23259949)
RGD
PMID:23259949
NCBI chr 6:95,051,527...95,061,075
Ensembl chr 6:95,051,537...95,061,578
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Ankrd1
ankyrin repeat domain 1
involved_in
IEA ISO
GO_REF:0000107 (PMID:17239933)
Ensembl RGD
PMID:17239933
GO_REF:0000107
NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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Asic2
acid sensing ion channel subunit 2
IDA
amiloride
RGD
PMID:12736332
RGD:1298620
NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
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Bcl2l1
Bcl2-like 1
IEP
carboplatin
RGD
PMID:18483861
RGD:2293312
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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Blm
BLM RecQ like helicase
acts_upstream_of_or_within
ISO
MGI:2448558 (PMID:25520194)
RGD
PMID:25520194
NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
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Braf
B-Raf proto-oncogene, serine/threonine kinase
acts_upstream_of_or_within
ISO
(PMID:22628551)
RGD
PMID:22628551
NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
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Cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
IEP
N-phosphonoacetyl-L-aspartate
RGD
PMID:8548770
RGD:5132280
NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861
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Ccl2
C-C motif chemokine ligand 2
IEP
nifedipine
RGD
PMID:16331110
RGD:2298662
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl4
C-C motif chemokine ligand 4
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:24486487)
Ensembl RGD
PMID:24486487
GO_REF:0000107
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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Cd69
Cd69 molecule
involved_in
ISO
(PMID:19109165)
RGD
PMID:19109165
NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
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Cdh13
cadherin 13
IEP
RGD
PMID:12559965
RGD:632357
NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459
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Cebpa
CCAAT/enhancer binding protein alpha
IEP
rosiglitazone
RGD
PMID:1377818
RGD:69946
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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Cers1
ceramide synthase 1
involved_in
ISO
(PMID:19800881)
RGD
PMID:19800881
NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519
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Chek2
checkpoint kinase 2
IEP
alpha-difluoromethylornithine
RGD
PMID:21745814
RGD:10401653
NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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Crhbp
corticotropin releasing hormone binding protein
involved_in
ISS ISO
GO_REF:0000024 (PMID:15976007)
UniProt RGD
PMID:15976007
GO_REF:0000024
NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
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Crkl
CRK like proto-oncogene, adaptor protein
acts_upstream_of_or_within
ISO
(PMID:29581031)
RGD
PMID:29581031
NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238
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Cxcr4
C-X-C motif chemokine receptor 4
IEP
RGD
PMID:20613717
RGD:11352688
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Ddc
dopa decarboxylase
IEP
L-DOPA
RGD
PMID:18602388
RGD:5129085
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
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Dpep1
dipeptidase 1
involved_in
ISO ISS
(PMID:20435919) GO_REF:0000024
RGD UniProt
PMID:20435919
GO_REF:0000024
NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
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E2f1
E2F transcription factor 1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:24726645)
Ensembl RGD
PMID:24726645
GO_REF:0000107
NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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Edn1
endothelin 1
IEP
cyclosporine
RGD
PMID:8129032
RGD:8662286
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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Eef1a1
eukaryotic translation elongation factor 1 alpha 1
IEP
cilostazol
RGD
PMID:21390260
RGD:10401124
NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
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Eftud2
elongation factor Tu GTP binding domain containing 2
IEP
flutamide
RGD
PMID:24793618
RGD:10045571
NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079
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Egfr
epidermal growth factor receptor
IEP
vorinostat NADPH oxidase inhibitors VAS2870, apocynin
RGD
PMID:21389970 PMID:21276422
RGD:5131459 , RGD:5131479
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Egr1
early growth response 1
IEP
imipramine
RGD
PMID:21354245
RGD:5131879
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Ehmt2
euchromatic histone lysine methyltransferase 2
IEP
amitriptyline
RGD
PMID:22880885
RGD:9588218
NCBI chr20:3,919,623...3,936,751
Ensembl chr20:3,919,624...3,941,547
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Ep300
E1A binding protein p300
IEP
valproic acid
RGD
PMID:20888352
RGD:7364728
NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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Esr2
estrogen receptor 2
IEP
tamoxifen
RGD
PMID:19279558
RGD:7364795
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Fancb
FA complementation group B
acts_upstream_of_or_within
ISO
MGI:1328362|MGI:2156841 (PMID:25520194)
RGD
PMID:25520194
NCBI chr X:29,403,771...29,420,484
Ensembl chr X:29,403,771...29,420,192
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Fbp1
fructose-bisphosphatase 1
involved_in
ISO IEA ISS
(PMID:16442285), (PMID:18650089) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:16442285 PMID:18650089
GO_REF:0000024 GO_REF:0000107
NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
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Fgf21
fibroblast growth factor 21
IEP
RGD
PMID:23118742
RGD:10401886
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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Gas6
growth arrest specific 6
involved_in
ISO IDA
(PMID:16359517) PMID:18374201
RGD
PMID:16359517 PMID:18374201
RGD:8554638
NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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Gpld1
glycosylphosphatidylinositol specific phospholipase D1
involved_in
ISO ISS IEA
(PMID:17761367) GO_REF:0000024 GO_REF:0000107
RGD UniProt Ensembl
PMID:17761367
GO_REF:0000024 GO_REF:0000107
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
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Gstm1
glutathione S-transferase mu 1
acts_upstream_of_or_within
ISO
(PMID:8512323)
RGD
PMID:8512323
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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Gstm3
glutathione S-transferase mu 3
acts_upstream_of_or_within
ISO
(PMID:8512323)
RGD
PMID:8512323
NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
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Hif1a
hypoxia inducible factor 1 subunit alpha
IEP
isoproterenol
RGD
PMID:20193759
RGD:9068889
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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Hsf1
heat shock transcription factor 1
IEP
amlodipine besylate, amlodipine camsylate
RGD
PMID:21988238
RGD:10402816
NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
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Hspa5
heat shock protein family A (Hsp70) member 5
IEP
RGD
PMID:18757512
RGD:11354916
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Htr1b
5-hydroxytryptamine receptor 1B
involved_in
ISO ISS
(PMID:1315531) GO_REF:0000024
RGD UniProt
PMID:1315531
GO_REF:0000024
NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
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Il1b
interleukin 1 beta
acts_upstream_of_or_within
ISO
(PMID:19158679)
RGD
PMID:19158679
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Itgb3
integrin subunit beta 3
IEP
RGD
PMID:12242040
RGD:4999478
NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
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Kcnc1
potassium voltage-gated channel subfamily C member 1
IEP
fluoxetine
RGD
PMID:11543764
RGD:9685702
NCBI chr 1:96,902,953...96,944,744
Ensembl chr 1:96,902,953...96,944,744
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Kcnd2
potassium voltage-gated channel subfamily D member 2
IEP
RGD
PMID:17293496
RGD:7247436
NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
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Kcne2
potassium voltage-gated channel subfamily E regulatory subunit 2
involved_in
ISO IDA
(PMID:10219239)
RGD
PMID:10219239 PMID:10219239
RGD:633041
NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
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Kcnh2
potassium voltage-gated channel subfamily H member 2
involved_in
ISO
(PMID:7604285)
RGD
PMID:7604285
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Kcnq1
potassium voltage-gated channel subfamily Q member 1
involved_in
ISO IEA
(PMID:9108097) GO_REF:0000107
RGD Ensembl
PMID:9108097
GO_REF:0000107
NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
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Kcnq2
potassium voltage-gated channel subfamily Q member 2
acts_upstream_of_or_within
ISO
(PMID:23259949)
RGD
PMID:23259949
NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
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Kcnq3
potassium voltage-gated channel subfamily Q member 3
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:23259949)
Ensembl RGD
PMID:23259949
GO_REF:0000107
NCBI chr 7:97,730,219...98,025,652
Ensembl chr 7:97,730,465...98,025,653
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Mcm7
minichromosome maintenance complex component 7
acts_upstream_of_or_within
ISO
(PMID:24726645)
RGD
PMID:24726645
NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
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Mef2c
myocyte enhancer factor 2C
involved_in
ISS ISO
GO_REF:0000024 (PMID:16775627)
UniProt RGD
PMID:16775627
GO_REF:0000024
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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Mmp1
matrix metallopeptidase 1
IEP
ibuprophen
RGD
PMID:19847888
RGD:7207385
NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Myc
MYC proto-oncogene, bHLH transcription factor
involved_in
IEP ISO
emodin (PMID:19179467) (PMID:17873522), (PMID:19179467)
RGD
PMID:17873522 PMID:19179467 PMID:17886230
RGD:10059617
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Mylk
myosin light chain kinase
acts_upstream_of_or_within
ISO
(PMID:18524939)
RGD
PMID:18524939
NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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Nfe2l2
NFE2 like bZIP transcription factor 2
acts_upstream_of_or_within
ISO
MGI:2386080 (PMID:24486487)
RGD
PMID:24486487
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nkx3-1
NK3 homeobox 1
involved_in
ISO
(PMID:18757402)
RGD
PMID:18757402
NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
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Nme1
NME/NM23 nucleoside diphosphate kinase 1
IEP
isoproterenol
RGD
PMID:11082283
RGD:2299080
NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
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Nos2
nitric oxide synthase 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:24486487)
Ensembl RGD
PMID:24486487
GO_REF:0000107
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
IDA IEP
RGD
PMID:29235094 PMID:27090119
RGD:15042872 , RGD:15090804
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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Pax6
paired box 6
IEP
pramipexole
RGD
PMID:19619535
RGD:8552332
NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014
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Pcna
proliferating cell nuclear antigen
acts_upstream_of_or_within
ISO
(PMID:24726645)
RGD
PMID:24726645
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pde2a
phosphodiesterase 2A
involved_in
ISO
(PMID:14687666)
RGD
PMID:14687666
NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434
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Pde4a
phosphodiesterase 4A
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:11267656)
Ensembl RGD
PMID:11267656
GO_REF:0000107
NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961
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Pde4b
phosphodiesterase 4B
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:11267656)
Ensembl RGD
PMID:11267656
GO_REF:0000107
NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
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Ppat
phosphoribosyl pyrophosphate amidotransferase
IEP
malotilate
RGD
PMID:3012070
RGD:5135033
NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144
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Ppm1e
protein phosphatase, Mg2+/Mn2+ dependent, 1E
involved_in
ISO
(PMID:20801214)
RGD
PMID:20801214
NCBI chr10:72,051,643...72,187,439
Ensembl chr10:72,055,208...72,187,282
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Ppm1f
protein phosphatase, Mg2+/Mn2+ dependent, 1F
involved_in
ISO ISS
(PMID:20801214) GO_REF:0000024
RGD UniProt
PMID:20801214
GO_REF:0000024
NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340
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Ppp1r12a
protein phosphatase 1, regulatory subunit 12A
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:18524939)
Ensembl RGD
PMID:18524939
GO_REF:0000107
NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
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Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
acts_upstream_of_or_within
ISO
(PMID:18524939)
RGD
PMID:18524939
NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
IEP
methapyrilene
RGD
PMID:23274394
RGD:9999168
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Ppp1r9b
protein phosphatase 1, regulatory subunit 9B
IEP
haloperidol
RGD
PMID:16844384
RGD:10043796
NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083
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Prkaa1
protein kinase AMP-activated catalytic subunit alpha 1
IEP
RGD
PMID:27090119
RGD:15090804
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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Prkaa2
protein kinase AMP-activated catalytic subunit alpha 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2448467 (PMID:23918774)
Ensembl RGD
PMID:23918774
GO_REF:0000107
NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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Prnp
prion protein
acts_upstream_of_or_within
ISO
(PMID:16254249)
RGD
PMID:16254249
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
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Qdpr
quinoid dihydropteridine reductase
IEP
theophylline
RGD
PMID:2484967
RGD:5128599
NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854
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Ranbp1
RAN binding protein 1
IEP
phenylephrine
RGD
PMID:25341891
RGD:9835001
NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
G
Rap1a
RAP1A, member of RAS oncogene family
IDA
rolipram
RGD
PMID:10908723
RGD:10003157
NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501
G
Rap1b
RAP1B, member of RAS oncogene family
IDA
rolipram
RGD
PMID:10908723
RGD:10003157
NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370
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Rap2a
RAP2A, member of RAS oncogene family
involved_in
ISO
(PMID:22797597)
RGD
PMID:22797597
NCBI chr15:97,596,848...97,597,338
Ensembl chr15:97,596,020...97,624,138
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Rapgef3
Rap guanine nucleotide exchange factor 3
IEP
roflumilast
RGD
PMID:18276108
RGD:9835371
NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521
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Rb1
RB transcriptional corepressor 1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1931018 (PMID:24726645)
Ensembl RGD
PMID:24726645
GO_REF:0000107
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
G
Rbm22
RNA binding motif protein 22
involved_in
ISO ISS
(PMID:21122810) GO_REF:0000024
RGD UniProt
PMID:21122810
GO_REF:0000024
NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569
G
Recql5
RecQ like helicase 5
acts_upstream_of_or_within
ISO
MGI:2448558 (PMID:25520194)
RGD
PMID:25520194
NCBI chr10:101,126,544...101,165,739
Ensembl chr10:101,126,547...101,165,652
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Reg3b
regenerating family member 3 beta
IEP
troglitazone
RGD
PMID:11854617
RGD:9831383
NCBI chr 4:110,861,775...110,865,015
Ensembl chr 4:110,861,775...110,865,015
G
Ren
renin
IEP
secretagogue C4880
RGD
PMID:21963836
RGD:6892652
NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
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Rest
RE1-silencing transcription factor
involved_in
ISO ISS IEA
(PMID:20564196) GO_REF:0000024 GO_REF:0000107
RGD UniProt Ensembl
PMID:20564196
GO_REF:0000024 GO_REF:0000107
NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
G
Rnf149
ring finger protein 149
acts_upstream_of_or_within
ISO
(PMID:22628551)
RGD
PMID:22628551
NCBI chr 9:41,826,825...41,854,381
Ensembl chr 9:41,830,233...41,854,279
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Serpine1
serpin family E member 1
IDA
valproic acid
RGD
PMID:23378038
RGD:8547945
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Slamf8
SLAM family member 8
acts_upstream_of_or_within
ISO
MGI:5442794 (PMID:22593622)
RGD
PMID:22593622
NCBI chr13:85,047,729...85,057,571
Ensembl chr13:85,047,727...85,057,211
G
Slc10a1
solute carrier family 10 member 1
IEP
RGD
PMID:27090119
RGD:15090804
NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
G
Slc18a2
solute carrier family 18 member A2
IMP
1-methyl-4-phenylpyridinium, acriflavine
RGD
PMID:20007701
RGD:5130957
NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
G
Slco1a4
solute carrier organic anion transporter family, member 1a4
IEP
RGD
PMID:27090119
RGD:15090804
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
G
Sox10
SRY-box transcription factor 10
IEP
arecaidine
RGD
PMID:24403178
RGD:12879828
NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544
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Tfrc
transferrin receptor
acts_upstream_of_or_within
ISO
(PMID:16254249)
RGD
PMID:16254249
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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Th
tyrosine hydroxylase
IEP
L-DOPA
RGD
PMID:18602388
RGD:5129085
NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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Tlr3
toll-like receptor 3
IEP
methimazole derivative C10
RGD
PMID:15661832
RGD:5128798
NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
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Tp53
tumor protein p53
involved_in
ISO IEA
(PMID:20810912) GO_REF:0000107
RGD Ensembl
PMID:20810912
GO_REF:0000107
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Txn1
thioredoxin 1
IEP
dipyridamole
RGD
PMID:20453393
RGD:5133719
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
G
Uchl1
ubiquitin C-terminal hydrolase L1
involved_in
ISO
(PMID:23064229)
RGD
PMID:23064229
NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
IEP
RGD
PMID:8632018
RGD:10769355
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Umps
uridine monophosphate synthetase
IEP
pyrazofurin
RGD
PMID:6134725
RGD:5132277
NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903
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Vegfa
vascular endothelial growth factor A
IEP
RGD
PMID:22326847
RGD:7421605
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Wdr35
WD repeat domain 35
IEP
RGD
PMID:18472094
RGD:11553927
NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029
G
Wnk4
WNK lysine deficient protein kinase 4
involved_in
ISO
(PMID:31496133)
RGD
PMID:31496133
NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
G
Ugt1a6
UDP glucuronosyltransferase family 1 member A6
IDA
RGD
PMID:16006569
RGD:1600442
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
As3mt
arsenite methyltransferase
involved_in
IDA IBA ISO IEA
PMID:11790780 GO_REF:0000033 (PMID:25997655) GO_REF:0000107
GO_Central RGD Ensembl
PMID:25997655 PMID:11790780
GO_REF:0000033 GO_REF:0000107, RGD:625365
NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872
G
N6amt1
N-6 adenine-specific DNA methyltransferase 1
involved_in
ISO
(PMID:25997655)
RGD
PMID:25997655
NCBI chr11:26,584,750...26,597,790
Ensembl chr11:26,584,724...26,608,248
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
IDA
RGD
PMID:16006569
RGD:1600442
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
IDA
RGD
PMID:16006569
RGD:1600442
NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
G
Dnaja2
DnaJ heat shock protein family (Hsp40) member A2
IEP
RGD
PMID:15270078
RGD:4891447
NCBI chr19:21,497,792...21,516,904
Ensembl chr19:21,497,729...21,516,901
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
IDA IMP
2,3,7,8-tetrachlorodibenzo-p-dioxin
RGD
PMID:15812643 PMID:12914780
RGD:2306662 , RGD:2306673
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Gstt1
glutathione S-transferase theta 1
IDA
RGD
PMID:11453994
RGD:7794854
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
IDA
Deltamethrin (pyrethroid)
RGD
PMID:16169030
RGD:2306660
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Aldh2
aldehyde dehydrogenase 2 family member
involved_in
ISS ISO
GO_REF:0000024 (PMID:19506075)
UniProt RGD
PMID:19506075
GO_REF:0000024
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
IEP
RGD
PMID:16520233
RGD:401900296
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Acaa1a
acetyl-CoA acyltransferase 1A
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
G
Acaa1b
acetyl-Coenzyme A acyltransferase 1B
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
G
Pon3
paraoxonase 3
IDA
RGD
PMID:12946270
RGD:1303961
NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855
G
Sufu
SUFU negative regulator of hedgehog signaling
IEP
RGD
PMID:30790292
RGD:150573813
NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
G
Grin1
glutamate ionotropic receptor NMDA type subunit 1
involved_in
ISO
(PMID:21795692)
RGD
PMID:21795692
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
G
Abcc1
ATP binding cassette subfamily C member 1
IDA
RGD
PMID:15198509
RGD:2303058
NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
G
Pon3
paraoxonase 3
involved_in
ISO IEA
(PMID:15772423) GO_REF:0000107
RGD Ensembl
PMID:15772423
GO_REF:0000107
NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855
G
Lpo
lactoperoxidase
involved_in
IEA
GO_REF:0000108
GOC
GO_REF:0000108
NCBI chr10:72,606,950...72,626,220
Ensembl chr10:72,606,944...72,626,535
G
Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
IDA
RGD
PMID:15987776
RGD:2301693
NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
G
Abcc2
ATP binding cassette subfamily C member 2
IMP
RGD
PMID:18088505
RGD:14700808
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
G
Acsl1
acyl-CoA synthetase long-chain family member 1
IDA
RGD
PMID:10725307
RGD:2312871
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
G
Cryz
crystallin zeta
involved_in
ISO IEA ISS
(PMID:17497241) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:17497241
GO_REF:0000024 GO_REF:0000107
NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
involved_in
ISO IEA
(PMID:18356043), (PMID:18619574) GO_REF:0000107
RGD Ensembl
PMID:18356043 PMID:18619574
GO_REF:0000107
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
involved_in
ISO
(PMID:19029318)
RGD
PMID:19029318
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
involved_in
ISO IDA
(PMID:19029318)
RGD
PMID:19029318 PMID:16039681
RGD:401965478
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
involved_in
ISO
(PMID:18619574)
RGD
PMID:18619574
G
Cyp2d1
cytochrome P450, family 2, subfamily d, polypeptide 1
involved_in NOT|involved_in
ISO
(PMID:15051713) (PMID:18838503)
RGD
PMID:15051713 PMID:18838503
NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
involved_in
ISO
(PMID:15039299)
RGD
PMID:15039299
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
involved_in
ISO
(PMID:15039299), (PMID:15327587), (PMID:18356043), (PMID:18619574)
RGD
PMID:15039299 PMID:15327587 PMID:18356043 PMID:18619574
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
G
Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
involved_in
ISO
(PMID:15039299)
RGD
PMID:15039299
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
G
Fmo4
flavin containing dimethylaniline monoxygenase 4
acts_upstream_of_or_within
ISO
MGI:5487815 (PMID:19262426)
RGD
PMID:19262426
NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874
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Gsta1
glutathione S-transferase alpha 1
involved_in
IDA
PMID:17112229
CAFA
PMID:17112229
RGD:12793043
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
G
Gsta2
glutathione S-transferase alpha 2
involved_in
IDA
PMID:17112229
CAFA
PMID:17112229
RGD:12793043
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
G
Gsta5
glutathione S-transferase alpha 5
involved_in
IDA
PMID:17112229
CAFA
PMID:17112229
RGD:12793043
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
G
Gstm1
glutathione S-transferase mu 1
involved_in
IDA ISO
PMID:17112229 (PMID:8373352)
RGD
PMID:8373352 PMID:17112229
RGD:12793043
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Gstm2
glutathione S-transferase mu 2
involved_in
IDA ISO
PMID:17112229 (PMID:16549767), (PMID:2034681), (PMID:8373352)
RGD
PMID:2034681 PMID:8373352 PMID:16549767 PMID:17112229
RGD:12793043
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
G
Gstm4
glutathione S-transferase mu 4
involved_in acts_upstream_of_or_within
ISO IEA
(PMID:8373352) (PMID:12069689) GO_REF:0000107
RGD Ensembl
PMID:8373352 PMID:12069689
GO_REF:0000107
NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
G
Gstm5
glutathione S-transferase, mu 5
involved_in
ISO
(PMID:8373352)
RGD
PMID:8373352
NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
G
Gstm7
glutathione S-transferase, mu 7
involved_in
IEA
GO_REF:0000107
Ensembl
GO_REF:0000107
NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203
G
Gsto1
glutathione S-transferase omega 1
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:12928150)
UniProt Ensembl RGD
PMID:12928150
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
G
Nos1
nitric oxide synthase 1
acts_upstream_of_or_within
ISO
MGI:1857227 (PMID:11158245)
RGD
PMID:11158245
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
involved_in
ISO ISS
(PMID:12578355) GO_REF:0000024
RGD UniProt
PMID:12578355
GO_REF:0000024
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nudt15
nudix hydrolase 15
involved_in
ISO
(PMID:26878724)
RGD
PMID:26878724
NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363
G
Ugt1a1
UDP glucuronosyltransferase family 1 member A1
involved_in
IDA ISO
(PMID:15472229), (PMID:18719240), (PMID:19830808), (PMID:20056724)
RGD
PMID:15472229 PMID:18719240 PMID:19830808 PMID:20056724 PMID:8806713
RGD:10769352
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a2
UDP glucuronosyltransferase 1 family, polypeptide A2
involved_in
ISO
(PMID:20056724)
RGD
PMID:20056724
NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a3
UDP glycosyltransferase 1 family, polypeptide A3
involved_in
ISS
GO_REF:0000024
UniProt
GO_REF:0000024
NCBI chr 9:88,780,328...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a9
UDP glucuronosyltransferase family 1 member A9
involved_in
ISO
(PMID:20056724)
RGD
PMID:20056724
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt2b34l1
UDP glucuronosyltransferase 2 family, polypeptide B34 like 1
involved_in
ISO
(PMID:11300766)
RGD
PMID:11300766
NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
G
Abcb11
ATP binding cassette subfamily B member 11
involved_in
ISO IEA ISS IMP
(PMID:18245269) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:18245269 PMID:18245269
GO_REF:0000024 GO_REF:0000107, RGD:30309924
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
G
Ahr
aryl hydrocarbon receptor
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
G
Ahrr
aryl-hydrocarbon receptor repressor
involved_in
IEA
GO_REF:0000002
InterPro
GO_REF:0000002
NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673
G
Aip
aryl-hydrocarbon receptor-interacting protein
acts_upstream_of_or_within
ISO
PR:P30561 (PMID:9083006)
RGD
PMID:9083006
NCBI chr 1:201,408,002...201,419,220
Ensembl chr 1:201,407,288...201,419,122
G
Aox1
aldehyde oxidase 1
involved_in
TAS ISO IEA ISS
(PMID:23462233) GO_REF:0000107 GO_REF:0000024 (PMID:20444863), (PMID:22031625), (PMID:22522748), (PMID:23857892)
RGD Ensembl UniProt
PMID:20444863 PMID:22031625 PMID:22522748 PMID:23462233 PMID:23857892 PMID:11913970 More...
GO_REF:0000024 GO_REF:0000107, RGD:730052
NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
G
Aox2
aldehyde oxidase 2
involved_in
ISS
GO_REF:0000024
UniProt
GO_REF:0000024
NCBI chr 9:59,828,403...59,916,175
Ensembl chr 9:59,828,084...59,916,146
G
Aox3
aldehyde oxidase 3
involved_in
ISS
GO_REF:0000024
UniProt
GO_REF:0000024
NCBI chr 9:59,664,784...59,749,701
Ensembl chr 9:59,664,809...59,818,169
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Aox4
aldehyde oxidase 4
involved_in
ISS
GO_REF:0000024
UniProt
GO_REF:0000024
NCBI chr 9:59,761,238...59,818,169
Ensembl chr 9:59,664,809...59,818,169
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Cad
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
IMP
RGD
PMID:18515330
RGD:2303526
NCBI chr 6:25,292,133...25,315,078
Ensembl chr 6:25,292,133...25,319,861
G
Cbr1
carbonyl reductase 1
involved_in
ISO ISS
(PMID:18449627) GO_REF:0000024
RGD UniProt
PMID:18449627
GO_REF:0000024
NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
involved_in
ISO
(PMID:19219744)
RGD
PMID:19219744
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
acts_upstream_of_or_within involved_in
IDA ISO
MGI:2182351 (PMID:8643688) (PMID:15327587), (PMID:19219744)
RGD
PMID:8643688 PMID:15327587 PMID:19219744 PMID:6772643
RGD:151347456
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
involved_in
IEA ISS ISO
GO_REF:0000107 GO_REF:0000024 (PMID:22888116)
Ensembl UniProt RGD
PMID:22888116
GO_REF:0000024 GO_REF:0000107
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
G
Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
involved_in
ISO
(PMID:26937021)
RGD
PMID:26937021
NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
G
Cyp26b1
cytochrome P450, family 26, subfamily b, polypeptide 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:26937021)
UniProt RGD
PMID:26937021
GO_REF:0000024
NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
G
Cyp2a1
cytochrome P450, family 2, subfamily a, polypeptide 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
G
Cyp2a2
cytochrome P450, family 2, subfamily a, polypeptide 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:82,263,833...82,289,487
Ensembl chr 1:82,263,833...82,289,487
G
Cyp2a3
cytochrome P450, family 2, subfamily a, polypeptide 3
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
G
Cyp2ab1
cytochrome P450, family 2, subfamily ab, polypeptide 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr11:80,582,633...80,591,217
Ensembl chr11:80,582,938...80,590,873
G
Cyp2ac1
cytochrome P450, family 2, subfamily ac, polypeptide 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 9:20,035,823...20,058,570
Ensembl chr 9:20,033,780...20,058,837
G
Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
involved_in
IDA IBA
GO_REF:0000033
GO_Central RGD
PMID:9425052
GO_REF:0000033, RGD:2301461
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
G
Cyp2b12
cytochrome P450, family 2, subfamily b, polypeptide 12
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:82,007,609...82,019,409
Ensembl chr 1:82,007,609...82,080,480
G
Cyp2b15
cytochrome P450, family 2, subfamily b, polypeptide 15
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
G
Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
involved_in
TAS IBA IDA
GO_REF:0000033
GO_Central RGD
PMID:11996101 PMID:9425052
GO_REF:0000033, RGD:1298848 , RGD:2301461
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
G
Cyp2b21
cytochrome P450, family 2, subfamily b, polypeptide 21
involved_in
NAS IBA
GO_REF:0000033
GO_Central RGD
PMID:11159754
GO_REF:0000033, RGD:1299648
NCBI chr 1:81,886,097...81,915,066
Ensembl chr 1:81,886,098...81,915,066
G
Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
involved_in
ISO IBA
(PMID:18356043), (PMID:19651758), (PMID:20061448) GO_REF:0000033
RGD GO_Central
PMID:18356043 PMID:19651758 PMID:20061448
GO_REF:0000033
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
G
Cyp2c11
cytochrome P450, subfamily 2, polypeptide 11
involved_in
TAS IBA
GO_REF:0000033
GO_Central RGD
PMID:8611037
GO_REF:0000033, RGD:1298853
NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
G
Cyp2c12
cytochrome P450, family 2, subfamily c, polypeptide 12
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
G
Cyp2c13
cytochrome P450, family 2, subfamily c, polypeptide 13
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:238,786,764...238,867,195
Ensembl chr 1:238,786,765...238,867,191
G
Cyp2c22
cytochrome P450, family 2, subfamily c, polypeptide 22
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738
G
Cyp2c23
cytochrome P450, family 2, subfamily c, polypeptide 23
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:242,889,218...242,913,869
Ensembl chr 1:242,889,224...242,913,858
G
Cyp2c24
cytochrome P450, family 2, subfamily c, polypeptide 24
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
G
Cyp2c55
cytochrome P450, family 2, subfamily c, polypeptide 55
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:237,009,411...237,054,555
Ensembl chr 1:237,009,368...237,054,564
G
Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
involved_in
NAS IBA ISO
GO_REF:0000033 (PMID:19219744), (PMID:19651758)
GO_Central RGD
PMID:19219744 PMID:19651758 PMID:12965116
GO_REF:0000033, RGD:728216
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp2c6-ps2
cytochrome P450, family 2, subfamily C, polypeptide 6, pseudogene 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:238,352,261...238,391,716
Ensembl chr 1:238,352,131...238,504,300
G
Cyp2c7
cytochrome P450, family 2, subfamily c, polypeptide 7
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:237,332,641...237,388,714
Ensembl chr 1:237,332,659...237,388,709
G
Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
involved_in
ISO
(PMID:19651758)
RGD
PMID:19651758
G
Cyp2d1
cytochrome P450, family 2, subfamily d, polypeptide 1
involved_in NOT|involved_in
ISO IBA
(PMID:15051713) GO_REF:0000033 (PMID:18838503)
RGD GO_Central
PMID:15051713 PMID:18838503
GO_REF:0000033
NCBI chr 7:113,908,950...113,913,420
Ensembl chr 7:113,908,947...113,922,084
G
Cyp2d2
cytochrome P450, family 2, subfamily d, polypeptide 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 7:113,935,138...113,939,209
Ensembl chr 7:113,935,138...113,939,209
G
Cyp2d3
cytochrome P450, family 2, subfamily d, polypeptide 3
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
G
Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
involved_in
IDA IBA ISO
GO_REF:0000033 (PMID:18356043), (PMID:19219744)
GO_Central RGD
PMID:18356043 PMID:19219744 PMID:8910433
GO_REF:0000033, RGD:728177
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
G
Cyp2d5
cytochrome P450, family 2, subfamily d, polypeptide 5
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 7:113,899,905...113,904,458
Ensembl chr 7:113,899,890...113,904,495
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
involved_in
NAS IBA IEA ISO IMP
GO_REF:0000033 GO_REF:0000107 (PMID:18356043), (PMID:19219744)
GO_Central Ensembl RGD
PMID:18356043 PMID:19219744 PMID:12220509 PMID:21187827
GO_REF:0000033 GO_REF:0000107, RGD:625597 , RGD:4892233
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
G
Cyp2g1
cytochrome P450, family 2, subfamily g, polypeptide 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828
G
Cyp2j10
cytochrome P450, family 2, subfamily j, polypeptide 10
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 5:110,960,319...110,995,220
Ensembl chr 5:110,960,317...110,995,115
G
Cyp2j16
cytochrome P450, family 2, subfamily j, polypeptide 16
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 5:111,089,438...111,138,918
Ensembl chr 5:111,088,674...111,139,013
G
Cyp2j3
cytochrome P450, family 2, subfamily j, polypeptide 3
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794
G
Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
G
Cyp2r1
cytochrome P450, family 2, subfamily r, polypeptide 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
G
Cyp2s1
cytochrome P450, family 2, subfamily s, polypeptide 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
G
Cyp2t1
cytochrome P450, family 2, subfamily t, polypeptide 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
G
Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
G
Cyp2w1
cytochrome P450, family 2, subfamily w, polypeptide 1
involved_in
ISO IBA
(PMID:16551781) GO_REF:0000033
RGD GO_Central
PMID:16551781
GO_REF:0000033
NCBI chr12:15,291,552...15,296,421
Ensembl chr12:15,291,704...15,296,421
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
involved_in
IDA ISO
(PMID:19219744)
RGD
PMID:19219744 PMID:12971802
RGD:5129544
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
G
Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
IDA
RGD
PMID:12971802
RGD:5129544
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
G
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
involved_in
ISO
(PMID:20667828)
RGD
PMID:20667828
NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760
G
Fmo1
flavin containing dimethylaniline monoxygenase 1
acts_upstream_of_or_within
ISO
MGI:5487815 (PMID:19262426)
RGD
PMID:19262426
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
G
Fmo2
flavin containing dimethylaniline monoxygenase 2
involved_in
IEA ISO
GO_REF:0000107 (PMID:11744609)
Ensembl RGD
PMID:11744609
GO_REF:0000107
NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
G
Fmo3
flavin containing dimethylaniline monoxygenase 3
IDA
RGD
PMID:17173378
RGD:1626480
NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028
G
Fmo5
flavin containing dimethylaniline monoxygenase 5
involved_in
ISO IEA ISS
(PMID:20947616), (PMID:28783300) GO_REF:0000107 GO_REF:0000024
RGD Ensembl UniProt
PMID:20947616 PMID:28783300
GO_REF:0000024 GO_REF:0000107
NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
G
Gsta1
glutathione S-transferase alpha 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
G
Gsta2
glutathione S-transferase alpha 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
G
Gsta3
glutathione S-transferase alpha 3
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
G
Gsta3l1
glutathione S-transferase alpha 3 like 1
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 9:23,619,691...23,628,517
Ensembl chr 9:23,620,010...23,632,333
G
Gsta4
glutathione S-transferase alpha 4
involved_in
ISO IBA
(PMID:10329152) GO_REF:0000033
RGD GO_Central
PMID:10329152
GO_REF:0000033
NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
G
Gsta5
glutathione S-transferase alpha 5
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
G
Gsta6
glutathione S-transferase alpha 6
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 9:23,743,262...23,806,260
Ensembl chr 9:23,744,288...23,801,131
G
Gstm2
glutathione S-transferase mu 2
TAS
RGD
PMID:3020050
RGD:730286
NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
G
Gsto2
glutathione S-transferase omega 2
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:15970797)
UniProt Ensembl RGD
PMID:15970797
GO_REF:0000024 GO_REF:0000107
NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
G
Gstp1
glutathione S-transferase pi 1
involved_in
TAS ISO
(PMID:1540159)
RGD
PMID:1540159 PMID:3029128
RGD:728729
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Guk1
guanylate kinase 1
involved_in
ISO
(PMID:6306664)
RGD
PMID:6306664
NCBI chr10:43,971,514...43,988,658
Ensembl chr10:43,971,509...43,980,107
G
Hnf4a
hepatocyte nuclear factor 4, alpha
involved_in acts_upstream_of_positive_effect
IEA ISO
GO_REF:0000107 (PMID:17827783)
Ensembl RGD
PMID:17827783
GO_REF:0000107
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
G
LOC103691092
cytochrome P450 2B9-like
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:81,791,776...81,810,482
Ensembl chr 1:81,784,649...81,810,482
G
Nceh1
neutral cholesterol ester hydrolase 1
acts_upstream_of_or_within
ISO
MGI:3629327 (PMID:15840715)
RGD
PMID:15840715
NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
involved_in
ISO ISS
(PMID:12578355) GO_REF:0000024
RGD UniProt
PMID:12578355
GO_REF:0000024
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
G
Rora
RAR-related orphan receptor A
involved_in
ISO
UniProtKB:P51450 (PMID:17666523)
RGD
PMID:17666523
NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931
G
Rorc
RAR-related orphan receptor C
involved_in
ISO
UniProtKB:P51448 (PMID:17666523)
RGD
PMID:17666523
NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
G
Sult1a1
sulfotransferase family 1A member 1
involved_in
TAS ISO IDA
(PMID:12471039), (PMID:20056724) nitrofen
RGD
PMID:12471039 PMID:20056724 PMID:1513323 PMID:6959650 PMID:14754874
RGD:730083 , RGD:2301075 , RGD:2301063
NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
G
Sult1b1
sulfotransferase family 1B member 1
involved_in
ISO
(PMID:20056724)
RGD
PMID:20056724
NCBI chr14:20,492,763...20,505,491
Ensembl chr14:20,492,708...20,505,483
G
Sult1c3
sulfotransferase family 1C member 3
involved_in
ISO
(PMID:28992322)
RGD
PMID:28992322
NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
G
Sult2a1
sulfotransferase family 2A member 1
involved_in
IDA ISS ISO
GO_REF:0000024 (PMID:7854148)
UniProt RGD
PMID:7854148 PMID:16099924
GO_REF:0000024, RGD:5129555
NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
G
Tpmt
thiopurine S-methyltransferase
involved_in
ISO IEA
(PMID:18484748), (PMID:657528) GO_REF:0000107
RGD Ensembl
PMID:657528 PMID:18484748
GO_REF:0000107
NCBI chr17:17,644,088...17,662,709
Ensembl chr17:17,644,173...17,662,709
G
Ugt1a6
UDP glucuronosyltransferase family 1 member A6
involved_in
ISO
(PMID:3141926)
RGD
PMID:3141926
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt1a9
UDP glucuronosyltransferase family 1 member A9
involved_in NOT|involved_in
ISO
(PMID:1910331) (PMID:20610558)
RGD
PMID:1910331 PMID:20610558
NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
TAS
RGD
PMID:3084479
RGD:1299519
NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
G
Vkorc1
vitamin K epoxide reductase complex, subunit 1
involved_in
ISO
(PMID:21127708)
RGD
PMID:21127708
NCBI chr 1:182,502,491...182,505,012
Ensembl chr 1:182,500,844...182,505,008
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