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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to metal ion
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Accession:GO:0071248 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
Synonyms:exact_synonym: cellular response to metal
 narrow_synonym: cellular response to heavy metal


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cellular response to metal ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule ISO titanium oxide particles RGD PMID:19653805 RGD:4892213 NCBI chr13:138,427,573...138,504,307
Ensembl chr13:138,427,533...138,504,310 		JBrowse link
G FSTL3 follistatin like 3 ISO potassium RGD PMID:14692692 RGD:1302294 NCBI chr 2:77,656,655...77,662,608
Ensembl chr 2:77,656,663...77,662,613 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 ISO hexavalent chromium RGD PMID:18602937 RGD:4890967 NCBI chr12:20,269,468...20,271,349
Ensembl chr12:20,269,056...20,271,548 		JBrowse link
G HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 ISO hexavalent chromium RGD PMID:18602937 RGD:4890967 NCBI chr 6:6,296,429...6,360,434
Ensembl chr 6:6,292,707...6,360,633 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO lanthanum RGD PMID:28722058 RGD:13439714 NCBI chr 6:17,292,962...17,302,593
Ensembl chr 6:17,292,770...17,302,590 		JBrowse link
G SERPINE1 serpin family E member 1 ISO barium RGD PMID:21596853 RGD:8547918 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SLC34A1 solute carrier family 34 member 1 ISO uranium RGD PMID:16476458 RGD:7243141 NCBI chr 2:80,548,208...80,563,380
Ensembl chr 2:80,548,232...80,563,321 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO hexavalent chromium RGD PMID:18602937 RGD:4890967 NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,377,521...48,385,462 		JBrowse link
G TLR9 toll like receptor 9 ISO titanium
tin		 RGD PMID:17415764 PMID:21308757 RGD:5129495 RGD:5130196 NCBI chr13:34,353,444...34,370,990
Ensembl chr13:34,349,609...34,357,673 		JBrowse link
cellular detoxification of cadmium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB6 ATP binding cassette subfamily B member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:121,246,180...121,254,350
Ensembl chr15:121,246,187...121,254,331 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:120,434,100...120,446,396
Ensembl chr15:120,433,952...120,446,396 		JBrowse link
G SLC39A8 solute carrier family 39 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:118,604,852...118,678,115
Ensembl chr 8:118,605,402...118,678,107 		JBrowse link
cellular response to aluminum ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO RGD PMID:22138567 RGD:6483058 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:20832780 RGD:9685488 NCBI chr14:107,263,546...107,390,923
Ensembl chr14:107,263,449...107,389,010 		JBrowse link
cellular response to cadmium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:17584760 RGD:8655656 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15219627) Ensembl
MGI		 PMID:15219627 GO_REF:0000107 NCBI chr 1:207,817,095...207,821,800
Ensembl chr 1:207,818,175...207,822,291 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO RGD PMID:17719163 RGD:4835171 NCBI chr 7:59,172,829...59,188,479
Ensembl chr 7:59,175,758...59,188,478 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16183037) Ensembl
MGI		 PMID:16183037 GO_REF:0000107 NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100 		JBrowse link
G DAXX death domain associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110 		JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO RGD PMID:24361405 RGD:9685430 NCBI chr 4:19,319,815...19,433,492
Ensembl chr 4:19,319,810...19,433,488 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:15219627) MGI PMID:15219627 NCBI chr17:29,997,397...30,001,704
Ensembl chr17:29,997,401...30,001,707 		JBrowse link
G GP91-PHOX NADPH oxidase heavy chain subunit ISO RGD PMID:21195169 RGD:11040689 NCBI chr  X:33,654,656...33,678,346
Ensembl chr  X:33,643,648...33,680,580 		JBrowse link
G GSN gelsolin ISO RGD PMID:16280379 RGD:1599859 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,307,008...261,372,848 		JBrowse link
G HESX1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15219627) Ensembl
MGI		 PMID:15219627 GO_REF:0000107 NCBI chr13:39,046,961...39,088,926
Ensembl chr13:39,046,465...39,088,875 		JBrowse link
G HMOX1 heme oxygenase 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:16183037) AgBase
MGI
Ensembl		 PMID:16183037 GO_REF:0000024 GO_REF:0000107
G HSF1 heat shock transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:463,531...486,483
Ensembl chr 4:463,393...486,473 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9736451 RGD:10059378 NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508 		JBrowse link
G LOC102166944 metallothionein-1E-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,660,665...18,662,000 JBrowse link
G MT-2B metallothionein-2A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,645,125...18,646,034
Ensembl chr 6:18,645,153...18,646,033 		JBrowse link
G MT1A metallothionein 1A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,672,016...18,673,673
Ensembl chr 6:18,672,001...18,673,672 		JBrowse link
G MT1D metallothionein-1E involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,650,985...18,652,317 JBrowse link
G MT3 metallothionein 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,261...18,636,131 		JBrowse link
G MT4 metallothionein 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,611,245...18,613,956
Ensembl chr 6:18,610,820...18,614,782 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO RGD PMID:12499121 RGD:2317151 NCBI chr13:66,038,669...66,045,478 JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit ISO RGD PMID:18703135 RGD:8694082 NCBI chr 6:52,373,266...52,402,048
Ensembl chr 6:52,377,979...52,402,045 		JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:17584760 RGD:8655656 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:15219627) MGI PMID:15219627 NCBI chr13:119,668,476...119,669,435
Ensembl chr13:119,668,476...119,669,435 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:17719163 RGD:4835171 NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,377,521...48,385,462 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr15:105,820,237...105,850,099
Ensembl chr15:105,818,858...105,850,233 		JBrowse link
G UBE2D3 ubiquitin conjugating enzyme E2 D3 ISO RGD PMID:21467746 RGD:13830870 NCBI chr 8:118,218,224...118,229,002
Ensembl chr 8:118,203,289...118,232,029 		JBrowse link
G UBE2D4 ubiquitin conjugating enzyme E2 D4 ISO RGD PMID:21467746 RGD:13830870 NCBI chr18:48,735,258...48,756,314
Ensembl chr18:48,733,395...48,756,291 		JBrowse link
cellular response to calcium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20935152)
(PMID:24037327)		 MGI
Ensembl		 PMID:20935152 PMID:24037327 GO_REF:0000107 NCBI chr 5:51,536,531...51,673,583
Ensembl chr 5:51,536,526...51,691,595 		JBrowse link
G ACER1 alkaline ceramidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:72,704,603...72,767,474
Ensembl chr 2:72,743,643...72,769,570 		JBrowse link
G ADCY8 adenylate cyclase 8 involved_in ISO PMID:19158400
PMID:20410303		 RGD
UniProt		 PMID:19158400 PMID:19305019 PMID:20410303 RGD:13800545 RGD:7241269 RGD:7242424 NCBI chr 4:9,645,398...9,867,065
Ensembl chr 4:9,645,659...9,866,550 		JBrowse link
G ADD1 adducin 1 involved_in ISO (PMID:25978380) CAFA PMID:25978380 NCBI chr 8:1,627,146...1,710,653
Ensembl chr 8:1,627,062...1,710,650 		JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 (PMID:24191038) GO_Central
MGI		 PMID:24191038 GO_REF:0000033 NCBI chr 2:97,703,648...98,277,847
Ensembl chr 2:97,735,053...98,275,748 		JBrowse link
G AGO2 argonaute RISC catalytic component 2 ISO RGD PMID:28404816 RGD:401900713 NCBI chr 4:2,966,794...3,012,388
Ensembl chr 4:2,919,511...3,015,334 		JBrowse link
G AKAP5 A-kinase anchoring protein 5 acts_upstream_of_or_within ISO (PMID:23259949) MGI PMID:23259949 NCBI chr 7:88,538,938...88,544,330
Ensembl chr 7:88,538,984...88,547,392 		JBrowse link
G AKR1C1 aldo-keto reductase family 1, member C1 involved_in ISO (PMID:22170488) UniProt PMID:22170488 NCBI chr10:65,580,297...65,594,998
Ensembl chr10:65,576,464...65,678,248 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,401,810...52,414,903 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:52,287,174...52,295,873
Ensembl chr12:52,287,160...52,295,871 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:7,371,328...7,438,111
Ensembl chr11:7,411,644...7,438,108 		JBrowse link
G ASPH aspartate beta-hydroxylase involved_in ISO (PMID:21062895) UniProt PMID:21062895 NCBI chr 4:71,902,891...72,107,047
Ensembl chr 4:71,903,318...72,107,044 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,991...9,132,553 		JBrowse link
G CACYBP calcyclin binding protein ISO RGD PMID:11927578 RGD:625428 NCBI chr 9:117,062,303...117,077,442
Ensembl chr 9:117,064,187...117,123,126 		JBrowse link
G CAPN3 calpain 3 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:128,960,117...129,013,508
Ensembl chr 1:128,960,118...129,013,546 		JBrowse link
G CARF calcium responsive transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:106,410,245...106,482,502
Ensembl chr15:106,410,491...106,466,799 		JBrowse link
G CHP2 calcineurin like EF-hand protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:22,473,241...22,478,697
Ensembl chr 3:22,473,247...22,478,588 		JBrowse link
G CLIC4 chloride intracellular channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:82,401,041...82,483,038
Ensembl chr 6:82,401,188...82,483,724 		JBrowse link
G CPNE1 copine 1 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr17:38,956,489...38,997,189
Ensembl chr17:38,956,673...38,964,890 		JBrowse link
G CPNE2 copine 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:19,046,795...19,096,111
Ensembl chr 6:19,046,795...19,096,107 		JBrowse link
G CPNE3 copine 3 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:50,276,330...50,345,400
Ensembl chr 4:50,276,426...50,345,366 		JBrowse link
G CPNE4 copine 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:367,801...963,775
Ensembl chr13:367,651...963,773 		JBrowse link
G CPNE5 copine 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:32,396,735...32,510,242
Ensembl chr 7:32,409,688...32,508,380 		JBrowse link
G CPNE6 copine 6 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:75,213,643...75,219,031
Ensembl chr 7:75,213,644...75,219,031 		JBrowse link
G CPNE7 copine 7 involved_in ISO (PMID:21087455) UniProt PMID:21087455 NCBI chr 6:393,756...410,781 JBrowse link
G CPNE8 copine 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:70,391,854...70,660,213
Ensembl chr 5:70,394,578...70,660,195 		JBrowse link
G CPNE9 copine family member 9 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:65,994,369...66,019,080
Ensembl chr13:65,995,534...66,019,077 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein involved_in ISO (PMID:15976007) UniProt PMID:15976007 NCBI chr 2:85,814,399...85,830,598
Ensembl chr 2:85,816,816...85,831,179 		JBrowse link
G CRP C-reactive protein, pentraxin-related ISO RGD PMID:22090504 RGD:6904210 NCBI chr 4:90,793,361...90,801,020
Ensembl chr 4:90,793,350...90,805,218 		JBrowse link
G DPEP1 dipeptidase 1 involved_in IDA (PMID:11139399), (PMID:17615681) UniProt PMID:11139399 PMID:17615681 NCBI chr 6:361,187...385,757
Ensembl chr 6:361,197...376,616 		JBrowse link
G ECT2 epithelial cell transforming 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:111,248,215...111,310,746
Ensembl chr13:111,248,131...111,314,828 		JBrowse link
G EDN1 endothelin 1 ISO RGD PMID:1852000 RGD:8662267 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase ISO RGD PMID:19188248 RGD:10401231 NCBI chr 3:23,887,120...23,980,231
Ensembl chr 3:23,887,125...23,956,373 		JBrowse link
G ENDOG endonuclease G ISO RGD PMID:12582256 RGD:9685368 NCBI chr 1:269,153,955...269,157,789
Ensembl chr 1:269,154,090...269,157,788 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19365557) Ensembl
MGI		 PMID:19365557 GO_REF:0000107 NCBI chr 7:98,449,508...98,451,971
Ensembl chr 7:98,449,349...98,455,554 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr 6:51,836,780...51,844,531
Ensembl chr 6:51,837,719...51,844,529 		JBrowse link
G FUS FUS RNA binding protein ISO RGD PMID:19103256 RGD:9685716 NCBI chr 3:17,314,936...17,326,663
Ensembl chr 3:17,314,332...17,326,637 		JBrowse link
G HPCA hippocalcin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:89,187,544...89,197,049
Ensembl chr 6:89,188,133...89,197,045 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:9058202 RGD:11354978 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G INHBB inhibin subunit beta B ISO RGD PMID:1634019 RGD:9743923 NCBI chr15:30,999,994...31,004,405
Ensembl chr15:30,999,520...31,004,405 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:53,020,479...53,129,964
Ensembl chr 7:52,958,106...53,129,958 		JBrowse link
G ITPKA inositol-trisphosphate 3-kinase A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:129,867,261...129,877,762
Ensembl chr 1:129,867,642...129,875,639 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in ISO (PMID:12747803), (PMID:1654894) UniProt PMID:1654894 PMID:12747803 NCBI chr10:14,362,883...14,469,586 JBrowse link
G ITPKC inositol-trisphosphate 3-kinase C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:48,943,207...48,962,101
Ensembl chr 6:48,943,357...48,961,438 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:19303854) MGI PMID:19303854 NCBI chr 6:153,686,425...153,687,635
Ensembl chr 6:153,685,682...153,687,636 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr 2:66,214,086...66,219,435
Ensembl chr 2:66,214,138...66,217,002 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:19303854) MGI PMID:19303854 NCBI chr 2:59,530,991...59,532,846 JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 ISO RGD PMID:8978827 RGD:150527856 NCBI chr17:51,032,163...51,152,566
Ensembl chr17:51,039,987...51,142,644 		JBrowse link
G KCNH1 potassium voltage-gated channel subfamily H member 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:8790430 GO_REF:0000107 RGD:9693720 NCBI chr 9:131,960,566...132,336,029
Ensembl chr 9:131,960,480...132,334,953 		JBrowse link
G KCNQ2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO (PMID:23259949) MGI PMID:23259949 NCBI chr17:62,459,277...62,506,403
Ensembl chr17:62,459,281...62,506,424 		JBrowse link
G KCNQ3 potassium voltage-gated channel subfamily Q member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23259949) Ensembl
MGI		 PMID:23259949 GO_REF:0000107 NCBI chr 4:8,669,969...8,978,656
Ensembl chr 4:8,669,121...8,970,342 		JBrowse link
G KRT10 keratin 10 acts_upstream_of_or_within ISO (PMID:19303854) MGI PMID:19303854 NCBI chr12:21,641,263...21,645,642
Ensembl chr12:21,641,271...21,646,377 		JBrowse link
G LGMN legumain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:114,176,217...114,210,096
Ensembl chr 7:114,173,693...114,217,102 		JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:71,602,888...71,613,331
Ensembl chr 2:71,602,770...71,613,312 		JBrowse link
G MEF2A myocyte enhancer factor 2A involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:138,398,270...138,508,639
Ensembl chr 1:138,341,158...138,511,314 		JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:96,122,407...96,296,927
Ensembl chr 2:96,124,168...96,296,810 		JBrowse link
G MICU1 mitochondrial calcium uptake 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:75,203,731...75,445,628
Ensembl chr14:75,203,752...75,445,626 		JBrowse link
G MICU2 mitochondrial calcium uptake 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:1,421,169...1,500,411
Ensembl chr11:1,421,171...1,500,396 		JBrowse link
G MICU3 mitochondrial calcium uptake family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:4,720,918...4,827,996
Ensembl chr17:4,721,164...4,823,695 		JBrowse link
G MYLK myosin light chain kinase acts_upstream_of_or_within ISO (PMID:18524939) MGI PMID:18524939 NCBI chr13:136,509,878...136,809,674
Ensembl chr13:136,509,755...136,809,668 		JBrowse link
G NCSTN nicastrin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24889619) Ensembl
MGI		 PMID:24889619 GO_REF:0000107 NCBI chr 4:90,121,209...90,142,934
Ensembl chr 4:90,119,002...90,142,890 		JBrowse link
G NEUROD2 neuronal differentiation 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,709,473...22,713,785
Ensembl chr12:22,709,609...22,713,778 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (PMID:23259949) MGI PMID:23259949 NCBI chr 1:145,940,099...146,002,897
Ensembl chr 1:145,911,046...146,008,139 		JBrowse link
G NFATC2 nuclear factor of activated T cells 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23259949) Ensembl
MGI		 PMID:23259949 GO_REF:0000107 NCBI chr17:52,743,570...52,907,373
Ensembl chr17:52,743,568...52,906,821 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 acts_upstream_of_or_within ISO (PMID:23219532) MGI PMID:23219532 NCBI chr 6:28,666,458...28,806,432
Ensembl chr 6:28,666,549...28,806,419 		JBrowse link
G NLGN1 neuroligin 1 involved_in ISO PMID:14522992 ARUK-UCL PMID:14522992 RGD:13210536 NCBI chr13:111,851,007...112,727,202
Ensembl chr13:112,035,854...112,725,618 		JBrowse link
G NRXN1 neurexin 1 involved_in ISO PMID:14522992 ARUK-UCL PMID:14522992 RGD:13210536 NCBI chr 3:89,799,426...90,914,205
Ensembl chr 3:89,803,519...90,382,034 		JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:131,002,973...131,058,932
Ensembl chr 8:131,005,407...131,058,932 		JBrowse link
G PLCD1 phospholipase C delta 1 ISO RGD PMID:21767260 RGD:7349319 NCBI chr13:22,851,581...22,872,950
Ensembl chr13:22,851,584...22,872,992 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:6,433,146...6,603,092
Ensembl chr 6:6,433,153...6,603,060 		JBrowse link
G PPIF peptidylprolyl isomerase F involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:81,674,671...81,681,977
Ensembl chr14:81,667,672...81,689,495 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:18322138 RGD:8693423 NCBI chr 2:136,497,780...136,522,630
Ensembl chr 2:136,494,541...136,522,646 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:25,745,902...25,783,524
Ensembl chr16:25,745,324...25,783,707 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:155,683,392...155,754,283
Ensembl chr 6:155,681,784...155,754,278 		JBrowse link
G RASA4B RAS p21 protein activator 4B involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:9,816,576...9,846,340 JBrowse link
G RASAL1 RAS protein activator like 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:38,598,901...38,633,190
Ensembl chr14:38,601,394...38,633,425 		JBrowse link
G RASGRP2 RAS guanyl releasing protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:7,424,805...7,440,404
Ensembl chr 2:7,422,846...7,440,404 		JBrowse link
G RYR1 ryanodine receptor 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:47,339,759...47,458,457
Ensembl chr 6:47,343,768...47,458,458 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:23,336,143...23,424,755
Ensembl chr13:23,336,153...23,424,755 		JBrowse link
G SLC25A23 solute carrier family 25 member 23 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23344948) Ensembl
MGI		 PMID:23344948 GO_REF:0000107 NCBI chr 2:72,625,544...72,643,572
Ensembl chr 2:72,625,583...72,641,791 		JBrowse link
G SLC25A24 solute carrier family 25 member 24 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:111,580,186...111,632,390
Ensembl chr 4:111,579,663...111,634,266 		JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,324,091...3,328,493
Ensembl chr 9:3,324,442...3,328,457 		JBrowse link
G SYT1 synaptotagmin 1 involved_in ISO PMID:12526776 ParkinsonsUK-UCL PMID:12526776 RGD:10047386 NCBI chr 5:101,871,313...102,394,310
Ensembl chr 5:101,871,314...102,215,581 		JBrowse link
G TJP1 tight junction protein 1 involved_in ISO (PMID:8636221) UniProt PMID:8636221 NCBI chr 1:144,930,387...145,195,857
Ensembl chr 1:144,930,370...145,195,836 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:207,212,339...207,263,313
Ensembl chr13:207,212,457...207,262,064 		JBrowse link
G TUBA1A tubulin alpha 1a involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:15,186,059...15,190,211
Ensembl chr 5:15,185,532...15,190,428 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in ISO PMID:24803536 UniProt PMID:24803536 RGD:12910999 NCBI chr 5:68,000,792...68,142,533
Ensembl chr 5:68,000,905...68,140,755 		JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207 		JBrowse link
G ZNF774 zinc finger protein 774 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:52,985,669...52,994,797
Ensembl chr 7:52,958,106...53,129,958 		JBrowse link
cellular response to cobalt ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:23814049 RGD:11341692 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:140,362,123...140,371,951
Ensembl chr14:140,362,127...140,371,907 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:15519734 RGD:8662904 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:10559391 RGD:2313660 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G SERPINF1 serpin family F member 1 ISO RGD PMID:21922517 RGD:8554899 NCBI chr12:47,949,004...47,959,471
Ensembl chr12:47,948,510...47,959,470 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:66,044,679...66,067,571
Ensembl chr 5:66,044,686...66,067,377 		JBrowse link
cellular response to copper ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein ISO RGD PMID:18583042 RGD:13782134 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746 		JBrowse link
G AQP2 aquaporin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:15,862,739...15,868,565
Ensembl chr 5:15,863,486...15,868,565 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:20671235 PMID:23174565 RGD:11341702 RGD:11341707 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G ATP7B ATPase copper transporting beta ISO RGD PMID:24614235 RGD:11341682 NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064 		JBrowse link
G BACE1 beta-secretase 1 ISO RGD PMID:18583042 RGD:13782134 NCBI chr 9:44,640,389...44,665,863
Ensembl chr 9:44,640,394...44,665,835 		JBrowse link
G BECN1 beclin 1 ISO RGD PMID:22540380 RGD:11561917 NCBI chr12:20,041,914...20,054,249
Ensembl chr12:20,041,956...20,054,373 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:24599699 RGD:11352816 NCBI chr 7:58,802,887...58,809,155
Ensembl chr 7:58,802,887...58,809,775 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO RGD PMID:24599699 RGD:11352816 NCBI chr 7:58,779,529...58,786,155
Ensembl chr 7:58,779,475...58,786,100 		JBrowse link
G DAXX death domain associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:29,676,854...29,681,145
Ensembl chr 7:29,676,856...29,681,110 		JBrowse link
G ELN elastin ISO RGD PMID:18847363 RGD:9585685 NCBI chr 3:11,214,194...11,245,891
Ensembl chr 3:11,214,205...11,244,897 		JBrowse link
G HSF1 heat shock transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:463,531...486,483
Ensembl chr 4:463,393...486,473 		JBrowse link
G LOC102166944 metallothionein-1E-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,660,665...18,662,000 JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:22540380 RGD:11561917 NCBI chr17:37,957,830...37,959,505
Ensembl chr17:37,957,507...37,959,505 		JBrowse link
G MT-2B metallothionein-2A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,645,125...18,646,034
Ensembl chr 6:18,645,153...18,646,033 		JBrowse link
G MT1A metallothionein 1A involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,672,016...18,673,673
Ensembl chr 6:18,672,001...18,673,672 		JBrowse link
G MT1D metallothionein-1E involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,650,985...18,652,317 JBrowse link
G MT3 metallothionein 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,261...18,636,131 		JBrowse link
G MT4 metallothionein 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,611,245...18,613,956
Ensembl chr 6:18,610,820...18,614,782 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO (PMID:24462598) MGI PMID:24462598 NCBI chr12:24,303,381...24,316,765
Ensembl chr12:24,303,399...24,316,763 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24462598) Ensembl
MGI		 PMID:24462598 GO_REF:0000107 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G PRNP prion protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16254249) MGI
Ensembl		 PMID:16254249 GO_REF:0000107 NCBI chr17:13,694,195...13,705,126
Ensembl chr17:13,694,190...13,705,124 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:129,247,724...129,388,307
Ensembl chr 8:129,248,819...129,271,128 		JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO RGD PMID:19781568 RGD:5130971 NCBI chr 5:80,170,334...80,213,889
Ensembl chr 5:80,172,260...80,236,219 		JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:19679821 PMID:23174565 RGD:11341702 RGD:11341808 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G B2M beta-2-microglobulin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582 		JBrowse link
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:17663481 RGD:5688717
G SLC25A39 solute carrier family 25 member 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:18,913,261...18,919,761
Ensembl chr12:18,915,422...18,919,757 		JBrowse link
G TF transferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:74,930,655...74,970,599
Ensembl chr13:74,930,655...74,972,763 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:7,221,654...7,244,626
Ensembl chr 7:7,221,656...7,244,612 		JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,539,316...8,553,993
Ensembl chr 3:8,539,320...8,578,763 		JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,554,322...8,568,774
Ensembl chr 3:8,539,320...8,578,763 		JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:19608791 RGD:10045561 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569 		JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin acts_upstream_of_or_within ISO (PMID:9531620) MGI PMID:9531620 NCBI chr 1:126,837,721...126,844,043
Ensembl chr 1:126,835,143...126,981,582 		JBrowse link
G CCNB1 cyclin B1 ISO ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chr16:47,338,239...47,348,385
Ensembl chr16:47,338,110...47,348,377 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16135072 PMID:17469137 RGD:12904039 RGD:12904046 NCBI chr 7:47,481,539...47,529,199
Ensembl chr 7:47,478,706...47,529,242 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:21683124 RGD:7207286 NCBI chr 9:33,411,738...33,420,205
Ensembl chr 9:33,411,065...33,420,076 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:21683124 RGD:7207286 NCBI chr17:48,179,690...48,186,782
Ensembl chr17:48,179,671...48,186,788 		JBrowse link
cellular response to lead ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase ISO lead, gallium RGD PMID:16566714 RGD:4144781 NCBI chr 1:254,015,426...254,027,584
Ensembl chr 1:254,011,833...254,027,537 		JBrowse link
G ANXA5 annexin A5 ISO RGD PMID:11578147 RGD:10053705 NCBI chr 8:102,387,833...102,420,868
Ensembl chr 8:102,388,103...102,425,750 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:24316150 RGD:11341684 NCBI chr  X:61,972,544...62,110,058
Ensembl chr  X:61,972,991...62,110,048 		JBrowse link
G CLDN1 claudin 1 ISO RGD PMID:17439918 RGD:11344879 NCBI chr13:127,714,857...127,730,628
Ensembl chr13:127,712,777...127,730,657 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:22764079 RGD:9588241 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,566...69,029,844 		JBrowse link
G HMBS hydroxymethylbilane synthase ISO RGD PMID:16566714 RGD:4144781 NCBI chr 9:46,300,039...46,308,681
Ensembl chr 9:46,300,050...46,308,868 		JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:33576715 RGD:155582212 NCBI chr10:30,975,639...30,987,955
Ensembl chr10:30,975,702...30,987,956 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:25193092 RGD:13207490 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G UCP2 uncoupling protein 2 ISO RGD PMID:33576715 RGD:155582212 NCBI chr 9:8,358,559...8,364,552
Ensembl chr 9:8,358,025...8,365,547 		JBrowse link
cellular response to lithium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY7 adenylate cyclase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:34,521,503...34,586,384
Ensembl chr 6:34,519,180...34,585,779 		JBrowse link
G CALR calreticulin ISO RGD PMID:16236328 RGD:2326183 NCBI chr 2:66,098,263...66,102,074
Ensembl chr 2:66,098,229...66,102,132 		JBrowse link
G CDH1 cadherin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19056892) MGI
Ensembl		 PMID:19056892 GO_REF:0000107 NCBI chr 5:59,731,224...59,735,831
Ensembl chr 5:59,731,206...59,735,831 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15673614) Ensembl
MGI		 PMID:15673614 GO_REF:0000107 NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,207...43,085,836 		JBrowse link
G CTNNB1 catenin beta 1 ISO RGD PMID:12610652 RGD:10395276 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311 		JBrowse link
G FABP4 fatty acid binding protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15673614) Ensembl
MGI		 PMID:15673614 GO_REF:0000107 NCBI chr 4:55,096,400...55,101,209
Ensembl chr 4:55,096,404...55,101,896 		JBrowse link
G FAS Fas cell surface death receptor acts_upstream_of_or_within ISO (PMID:20530871) MGI PMID:20530871 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15673614) Ensembl
MGI		 PMID:15673614 GO_REF:0000107 NCBI chr 6:49,690,319...49,700,735
Ensembl chr 6:49,690,370...49,701,189 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:18932008 RGD:10045540 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569 		JBrowse link
G GSTA4 glutathione S-transferase alpha 4 ISO RGD PMID:18082333 RGD:2293846 NCBI chr 7:46,635,903...46,656,491
Ensembl chr 7:46,635,902...46,656,450 		JBrowse link
G ID2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (PMID:18367557) MGI PMID:18367557 NCBI chr 3:127,500,759...127,503,207
Ensembl chr 3:127,500,763...127,503,257 		JBrowse link
G LIG4 DNA ligase 4 ISO RGD PMID:19285016 RGD:2317095 NCBI chr11:75,537,027...75,547,711
Ensembl chr11:75,537,036...75,547,716 		JBrowse link
G MYOG myogenin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15673614) Ensembl
MGI		 PMID:15673614 GO_REF:0000107 NCBI chr 9:113,783,233...113,785,312
Ensembl chr 9:113,782,284...113,787,340 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 acts_upstream_of_or_within ISO (PMID:20530871) MGI PMID:20530871 NCBI chr 6:28,666,458...28,806,432
Ensembl chr 6:28,666,549...28,806,419 		JBrowse link
G NFATC4 nuclear factor of activated T cells 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20530871) Ensembl
MGI		 PMID:20530871 GO_REF:0000107 NCBI chr 7:74,918,982...74,929,688
Ensembl chr 7:74,918,984...74,929,600 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:21994254 RGD:5508722 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NTS neurotensin ISO RGD PMID:7898306 RGD:9743905 NCBI chr 5:96,261,299...96,272,947
Ensembl chr 5:96,260,560...96,272,976 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within ISO (PMID:15673614) MGI PMID:15673614 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17284610) Ensembl
MGI		 PMID:17284610 GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484 		JBrowse link
G SLC13A2 solute carrier family 13 member 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:44,733,038...44,754,476
Ensembl chr12:44,730,773...44,754,468 		JBrowse link
G SLC13A5 solute carrier family 13 member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:50,679,900...50,710,985
Ensembl chr12:50,680,444...50,705,261 		JBrowse link
G SLC18A1 solute carrier family 18 member A1 ISO RGD PMID:11080216 RGD:5131196 NCBI chr14:4,243,553...4,279,341
Ensembl chr14:4,243,557...4,275,243 		JBrowse link
G TPH2 tryptophan hydroxylase 2 ISO RGD PMID:19840776 RGD:2317083 NCBI chr 5:35,917,159...36,016,981
Ensembl chr 5:35,918,370...36,017,509 		JBrowse link
G VCAN versican ISO RGD PMID:19285016 RGD:2317095 NCBI chr 2:91,358,348...91,643,697
Ensembl chr 2:91,384,391...91,811,208 		JBrowse link
cellular response to magnesium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK3 ankyrin 3 involved_in ISO (PMID:23903368) UniProt PMID:23903368 NCBI chr14:63,416,154...63,809,220
Ensembl chr14:63,416,161...64,194,128 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding ISO RGD PMID:30950934 RGD:153350153 NCBI chr 3:7,867,521...7,874,857 JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:27,588,609...27,622,225
Ensembl chr10:27,588,570...27,622,674 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19154422 RGD:2326036 NCBI chr 3:32,749,329...33,149,350
Ensembl chr 3:32,750,700...33,143,499 		JBrowse link
G KCNA1 potassium voltage-gated channel subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:65,556,837...65,565,880
Ensembl chr 5:65,561,962...65,565,116 		JBrowse link
G KCNJ1 potassium inwardly rectifying channel subfamily J member 1 ISO RGD PMID:21030597 RGD:7244391 NCBI chr 9:55,779,020...55,812,761
Ensembl chr 9:55,780,257...55,781,375 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO RGD PMID:15919495 RGD:7794721 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:20350433 RGD:4892212 NCBI chr 2:144,822,937...144,956,451
Ensembl chr 2:144,822,939...144,956,451 		JBrowse link
G SLC41A1 solute carrier family 41 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:66,473,369...66,500,367
Ensembl chr 9:66,473,341...66,499,805 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23973266) Ensembl
MGI		 PMID:23973266 GO_REF:0000107 NCBI chr 6:28,938,287...29,025,397
Ensembl chr 6:28,938,290...29,025,357 		JBrowse link
cellular response to manganese ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3GALT2 alpha 1,3-galactosyltransferase 2 ISO RGD PMID:1569388 RGD:13831122 NCBI chr 6:89,557,492...89,562,835
Ensembl chr 6:89,558,423...89,562,490 		JBrowse link
G APP amyloid beta precursor protein ISO RGD PMID:18583042 RGD:13782134 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G ATP13A2 ATPase cation transporting 13A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:75,618,317...75,638,591
Ensembl chr 6:75,618,319...75,638,591 		JBrowse link
G ATP7B ATPase copper transporting beta ISO RGD PMID:24614235 RGD:11341682 NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064 		JBrowse link
G BACE1 beta-secretase 1 ISO RGD PMID:18583042 RGD:13782134 NCBI chr 9:44,640,389...44,665,863
Ensembl chr 9:44,640,394...44,665,835 		JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:19276553 RGD:5129515 NCBI chr 1:273,204,407...273,225,562
Ensembl chr 1:273,204,175...273,225,552 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr12:14,881,913...14,963,290
Ensembl chr12:14,881,923...14,963,284 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:19643132 RGD:2325970
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19643132 RGD:2325970 NCBI chr 3:32,749,329...33,149,350
Ensembl chr 3:32,750,700...33,143,499 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:19643132 RGD:2325970 NCBI chr 5:58,477,862...58,948,735
Ensembl chr 5:58,480,528...58,927,558 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 5:80,511,513...80,531,016
Ensembl chr 5:80,511,506...80,530,991 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,894 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16568477 PMID:17469137 RGD:12904039 RGD:12904041 NCBI chr 7:47,481,539...47,529,199
Ensembl chr 7:47,478,706...47,529,242 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:28232070 RGD:12910738 NCBI chr 6:72,026,512...72,056,439
Ensembl chr 6:72,028,499...72,056,438 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:19781568 RGD:5130971 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,312...6,730,872 		JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:19781568 RGD:5130971 NCBI chr 2:1,499,628...1,506,180
Ensembl chr 2:1,499,620...1,506,170 		JBrowse link
cellular response to mercury ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 (Colton blood group) involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:42,063,482...42,076,741
Ensembl chr18:42,063,485...42,076,746 		JBrowse link
G AQP2 aquaporin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:15,862,739...15,868,565
Ensembl chr 5:15,863,486...15,868,565 		JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:11768240 RGD:729934 NCBI chr15:117,658,158...117,737,145
Ensembl chr15:117,658,099...117,731,043 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ISO RGD PMID:2253967 RGD:4889587 NCBI chr 4:101,565,229...101,574,110 JBrowse link
G IL4 interleukin 4 ISO RGD PMID:7657819 PMID:19604304 RGD:2317279 RGD:2317674 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G NOX1 NADPH oxidase 1 ISO RGD PMID:28935286 RGD:329961577 NCBI chr  X:82,540,664...82,575,811
Ensembl chr  X:82,540,667...82,586,532 		JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:28935286 RGD:329961577 NCBI chr 9:22,622,105...22,776,691
Ensembl chr 9:22,624,212...22,776,534 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15635608) Ensembl
MGI		 PMID:15635608 GO_REF:0000107 NCBI chr 1:217,366,493...217,441,643
Ensembl chr 1:217,366,499...217,441,674 		JBrowse link
G UBE2D3 ubiquitin conjugating enzyme E2 D3 ISO RGD PMID:24212999 RGD:13830869 NCBI chr 8:118,218,224...118,229,002
Ensembl chr 8:118,203,289...118,232,029 		JBrowse link
cellular response to potassium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20935152) MGI
Ensembl		 PMID:20935152 GO_REF:0000107 NCBI chr 5:51,536,531...51,673,583
Ensembl chr 5:51,536,526...51,691,595 		JBrowse link
G ACTA1 actin alpha 1, skeletal muscle ISO RGD PMID:17146758 RGD:1598717 NCBI chr14:60,412,651...60,415,687
Ensembl chr14:60,412,812...60,415,674 		JBrowse link
G BDNF brain derived neurotrophic factor ISO RGD PMID:25424568 RGD:11060597 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,624,048...32,679,765 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:40,637,420...40,694,616
Ensembl chr 3:40,637,427...40,695,177 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,814,399...85,830,598
Ensembl chr 2:85,816,816...85,831,179 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in ISO (PMID:19342457) UniProt PMID:19342457 NCBI chr 4:1,365,725...1,373,138 JBrowse link
G DLG2 discs large MAGUK scaffold protein 2 involved_in ISO (PMID:26609151) ARUK-UCL PMID:26609151 NCBI chr 9:17,575,991...19,547,417
Ensembl chr 9:17,576,135...19,545,916 		JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,550,138...52,574,021
Ensembl chr12:52,550,141...52,575,143 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 ISO RGD PMID:15028757 RGD:1300188 NCBI chr  X:120,361,232...120,400,282
Ensembl chr  X:120,361,367...120,399,831 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO RGD PMID:17298175 RGD:10045993 NCBI chr 5:19,485,033...19,491,418
Ensembl chr 5:19,485,096...19,491,417 		JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:24478344 RGD:10402566 NCBI chr 4:463,531...486,483
Ensembl chr 4:463,393...486,473 		JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:90,421,956...90,457,406
Ensembl chr 4:90,422,025...90,457,406 		JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:14593183 RGD:12790707 NCBI chr  X:124,735,523...124,789,063
Ensembl chr  X:124,735,656...124,738,659 		JBrowse link
G MYLK myosin light chain kinase acts_upstream_of_or_within ISO (PMID:18524939) MGI PMID:18524939 NCBI chr13:136,509,878...136,809,674
Ensembl chr13:136,509,755...136,809,668 		JBrowse link
G NEK7 NIMA related kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:20,966,660...21,124,283
Ensembl chr10:20,966,651...21,124,271 		JBrowse link
G NPTX1 neuronal pentraxin 1 ISO RGD PMID:22279230 RGD:6903322 NCBI chr12:2,036,727...2,046,202
Ensembl chr12:2,036,810...2,046,193 		JBrowse link
G NRG1 neuregulin 1 ISO RGD PMID:26043693 RGD:405650602 NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,630,679...52,839,505 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:17870059 RGD:10059655 NCBI chr 8:17,841,844...18,527,953
Ensembl chr 8:17,841,844...17,946,992 		JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:21596853 RGD:8547918 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SLC12A2 solute carrier family 12 member 2 involved_in ISO (PMID:11940530) ARUK-UCL PMID:11940530 NCBI chr 2:131,016,430...131,109,307
Ensembl chr 2:131,016,418...131,109,299 		JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:17403136 RGD:8657024 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G STK39 serine/threonine kinase 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:74,441,019...74,757,851
Ensembl chr15:74,447,787...74,758,122 		JBrowse link
cellular response to zinc ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23716681) Ensembl
MGI		 PMID:23716681 GO_REF:0000107 NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,705,496...110,771,728 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 acts_upstream_of_or_within ISO (PMID:12183328) MGI PMID:12183328 NCBI chr 1:140,566,443...140,906,516
Ensembl chr 1:140,566,540...140,905,623 		JBrowse link
G GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 ISO RGD PMID:20371809 RGD:402464051 NCBI chr16:61,441,622...61,543,375
Ensembl chr16:61,441,632...61,543,361 		JBrowse link
G GLRA1 glycine receptor alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:71,140,751...71,236,867
Ensembl chr16:71,142,198...71,230,344 		JBrowse link
G GLRA2 glycine receptor alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:11,111,655...11,288,496
Ensembl chr  X:11,111,822...11,288,587 		JBrowse link
G GLRA3 glycine receptor alpha 3 involved_in ISO PMID:23895467 UniProt PMID:23895467 RGD:11035333 NCBI chr14:15,120,091...15,603,509
Ensembl chr14:15,423,767...15,595,422 		JBrowse link
G GPR39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (PMID:23133519)
(PMID:26375174)		 MGI PMID:23133519 PMID:26375174 NCBI chr15:19,556,066...19,801,203
Ensembl chr15:19,557,893...19,799,040 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19240037 RGD:2326029 NCBI chr 3:32,749,329...33,149,350
Ensembl chr 3:32,750,700...33,143,499 		JBrowse link
G HVCN1 hydrogen voltage gated channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:32,006,837...32,044,165
Ensembl chr14:31,989,170...32,043,744 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 ISO RGD PMID:9437008 RGD:61647 NCBI chr 3:112,322,446...112,359,212
Ensembl chr 3:112,322,446...112,359,212 		JBrowse link
G LOC102166944 metallothionein-1E-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,660,665...18,662,000 JBrowse link
G MT-2B metallothionein-2A involved_in ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:18,645,125...18,646,034
Ensembl chr 6:18,645,153...18,646,033 		JBrowse link
G MT1A metallothionein 1A involved_in ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:18,672,016...18,673,673
Ensembl chr 6:18,672,001...18,673,672 		JBrowse link
G MT1D metallothionein-1E involved_in ISS
IBA		 UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:18,650,985...18,652,317 JBrowse link
G MT3 metallothionein 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,634,735...18,636,134
Ensembl chr 6:18,634,261...18,636,131 		JBrowse link
G MT4 metallothionein 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,611,245...18,613,956
Ensembl chr 6:18,610,820...18,614,782 		JBrowse link
G MTF1 metal regulatory transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:93,837,195...93,884,427
Ensembl chr 6:93,839,205...93,884,409 		JBrowse link
G P2RX4 purinergic receptor P2X 4 involved_in ISO PMID:8551329 UniProt PMID:8551329 RGD:61682 NCBI chr14:31,368,542...31,387,960
Ensembl chr14:31,368,303...31,387,905 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:23582235 RGD:10414068 NCBI chr10:14,203,157...14,241,164
Ensembl chr10:14,203,160...14,241,196 		JBrowse link
G TSPO translocator protein ISO RGD PMID:18709649 RGD:2317141 NCBI chr 5:5,723,190...5,735,097
Ensembl chr 5:5,723,190...5,735,131 		JBrowse link
G ZNF658 zinc finger protein 658 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:38,797,314...38,818,459
Ensembl chr10:38,797,315...38,818,047 		JBrowse link
response to manganese-induced endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18933
    response to stimulus 10090
      response to chemical 5798
        response to metal ion 516
          cellular response to metal ion 252
            cellular response to aluminum ion 2
            cellular response to cadmium ion + 30
            cellular response to calcium ion + 89
            cellular response to cesium ion 0
            cellular response to cobalt ion 6
            cellular response to copper ion + 24
            cellular response to iron ion + 15
            cellular response to lead ion 9
            cellular response to lithium ion 25
            cellular response to magnesium ion 10
            cellular response to manganese ion + 21
            cellular response to mercury ion 9
            cellular response to nickel ion 0
            cellular response to platinum ion 0
            cellular response to potassium ion + 22
            cellular response to selenium ion 0
            cellular response to silver ion 0
            cellular response to tellurium ion 0
            cellular response to zinc ion 21
paths to the root