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ONTOLOGY REPORT - ANNOTATIONS

Term:cellular response to metal ion
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Accession:GO:0071248 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
Synonyms:exact_synonym: cellular response to metal
 narrow_synonym: cellular response to heavy metal


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cellular response to metal ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD86 CD86 molecule ISO titanium oxide particles RGD PMID:19653805 RGD:4892213 NCBI chr33:25,256,267...25,318,855
Ensembl chr33:25,256,267...25,318,087 		JBrowse link
G FSTL3 follistatin like 3 ISO potassium RGD PMID:14692692 RGD:1302294 NCBI chr20:57,878,623...57,884,240
Ensembl chr20:57,879,722...57,884,172 		JBrowse link
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 ISO hexavalent chromium RGD PMID:18602937 RGD:4890967 NCBI chr 9:20,402,124...20,407,143
Ensembl chr 9:20,405,019...20,406,792 		JBrowse link
G HSD17B2 hydroxysteroid 17-beta dehydrogenase 2 ISO hexavalent chromium RGD PMID:18602937 RGD:4890967 NCBI chr 5:69,927,888...70,009,306
Ensembl chr 5:69,927,984...70,009,179 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 ISO lanthanum RGD PMID:28722058 RGD:13439714 NCBI chr 5:79,979,593...79,990,875
Ensembl chr 5:79,978,865...79,989,860 		JBrowse link
G SERPINE1 serpin family E member 1 ISO barium RGD PMID:21596853 RGD:8547918 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301 		JBrowse link
G SLC34A1 solute carrier family 34 member 1 ISO uranium RGD PMID:16476458 RGD:7243141 NCBI chr 4:35,961,394...35,973,733
Ensembl chr 4:35,961,958...35,973,657 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO hexavalent chromium RGD PMID:18602937 RGD:4890967 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025 		JBrowse link
G TLR9 toll like receptor 9 ISO titanium
tin		 RGD PMID:17415764 PMID:21308757 RGD:5129495 RGD:5130196 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
cellular detoxification of cadmium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB6 ATP binding cassette subfamily B member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:25,760,478...25,767,753
Ensembl chr37:25,760,477...25,769,841 		JBrowse link
G SLC11A1 solute carrier family 11 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:25,039,203...25,047,461
Ensembl chr37:25,038,360...25,047,282 		JBrowse link
G SLC39A8 solute carrier family 39 member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:23,727,920...23,801,459
Ensembl chr32:23,729,476...23,800,941 		JBrowse link
cellular response to aluminum ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 ISO RGD PMID:22138567 RGD:6483058 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 ISO RGD PMID:20832780 RGD:9685488 NCBI chr28:9,181,851...9,311,835
Ensembl chr28:9,211,050...9,323,939 		JBrowse link
cellular response to cadmium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:17584760 RGD:8655656 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G CER1 cerberus 1, DAN family BMP antagonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15219627) Ensembl
MGI		 PMID:15219627 GO_REF:0000107 NCBI chr11:35,155,568...35,159,085
Ensembl chr11:35,156,430...35,158,942 		JBrowse link
G CYBB cytochrome b-245 beta chain ISO RGD PMID:21195169 RGD:11040689 NCBI chr  X:32,533,365...32,568,149
Ensembl chr  X:32,533,320...32,568,217 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO RGD PMID:17719163 RGD:4835171 NCBI chr30:37,474,997...37,487,028
Ensembl chr30:37,473,901...37,487,507 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16183037) Ensembl
MGI		 PMID:16183037 GO_REF:0000107 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G CYP2A13 cytochrome P450 family 2 subfamily A polypeptide 13 acts_upstream_of_or_within ISO (PMID:16183037) MGI PMID:16183037 NCBI chr 1:112,932,246...112,938,248
Ensembl chr 1:112,931,985...112,938,350 		JBrowse link
G DAXX death domain associated protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:2,755,960...2,760,687
Ensembl chr12:2,755,960...2,761,340 		JBrowse link
G ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 ISO RGD PMID:24361405 RGD:9685430 NCBI chr13:18,586,886...18,697,339
Ensembl chr13:18,587,129...18,697,324 		JBrowse link
G FOXA2 forkhead box A2 acts_upstream_of_or_within ISO (PMID:15219627) MGI PMID:15219627 NCBI chr24:1,010,370...1,013,791
Ensembl chr24:1,010,651...1,013,072 		JBrowse link
G GSN gelsolin ISO RGD PMID:16280379 RGD:1599859 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G HESX1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15219627) Ensembl
MGI		 PMID:15219627 GO_REF:0000107 NCBI chr20:33,193,813...33,197,226
Ensembl chr20:33,195,123...33,196,601 		JBrowse link
G HMOX1 heme oxygenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16183037) Ensembl
MGI		 PMID:16183037 GO_REF:0000107 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773 		JBrowse link
G HSF1 heat shock transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9736451 RGD:10059378 NCBI chr 5:11,292,219...11,296,851
Ensembl chr 5:11,292,262...11,296,797 		JBrowse link
G LOC100686073 metallothionein-1 involved_in ISO (PMID:16827180) UniProt PMID:16827180 NCBI chr 2:59,603,021...59,604,173
Ensembl chr 2:59,603,014...59,604,132 		JBrowse link
G LOC100687870 metallothionein-2-like involved_in ISO (PMID:16827180) UniProt PMID:16827180 NCBI chr 5:27,798,985...27,799,174 JBrowse link
G LOC100688390 metallothionein-2-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:46,319,153...46,319,335 JBrowse link
G LOC119877135 metallothionein-2-like involved_in IBA GO_Central GO_REF:0000033
G MT-III transcription initiation factor TFIID subunit 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G MT1E metallothionein 1E involved_in ISO (PMID:16827180), (PMID:19330122), (PMID:3403543) UniProt PMID:3403543 PMID:16827180 PMID:19330122
G MT4 metallothionein 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:59,640,784...59,643,370
Ensembl chr 2:59,640,784...59,643,370 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase ISO RGD PMID:12499121 RGD:2317151 NCBI chr20:8,486,150...8,491,448
Ensembl chr20:8,480,005...8,491,264 		JBrowse link
G PPP5C protein phosphatase 5 catalytic subunit ISO RGD PMID:18703135 RGD:8694082 NCBI chr 1:109,453,768...109,470,933
Ensembl chr 1:109,454,107...109,467,087 		JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:17584760 RGD:8655656 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G SOX2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO (PMID:15219627) MGI PMID:15219627 NCBI chr34:14,853,000...14,855,153 JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:17719163 RGD:4835171 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISO (PMID:11514557) UniProt PMID:11514557 NCBI chr37:11,199,937...11,229,743
Ensembl chr37:11,200,590...11,229,754 		JBrowse link
G UBE2D3 ubiquitin conjugating enzyme E2 D3 ISO RGD PMID:21467746 RGD:13830870 NCBI chr32:24,190,897...24,221,627 JBrowse link
cellular response to calcium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20935152)
(PMID:24037327)		 MGI
Ensembl		 PMID:20935152 PMID:24037327 GO_REF:0000107 NCBI chr27:25,199,580...25,352,637
Ensembl chr27:25,200,418...25,388,477 		JBrowse link
G ACER1 alkaline ceramidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:53,819,224...53,838,183
Ensembl chr20:53,819,074...53,838,438 		JBrowse link
G ADCY8 adenylate cyclase 8 involved_in ISO PMID:19158400
PMID:20410303		 RGD
UniProt		 PMID:19158400 PMID:19305019 PMID:20410303 RGD:13800545 RGD:7241269 RGD:7242424 NCBI chr13:27,723,530...27,937,821
Ensembl chr13:27,723,530...27,937,734 		JBrowse link
G ADD1 adducin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:61,356,643...61,443,851
Ensembl chr 3:61,358,162...61,474,830 		JBrowse link
G ADGRV1 adhesion G protein-coupled receptor V1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:24191038) MGI
GO_Central		 PMID:24191038 GO_REF:0000033 NCBI chr 3:17,866,459...18,351,532
Ensembl chr 3:17,866,808...18,351,532 		JBrowse link
G AGO2 argonaute RISC catalytic component 2 ISO RGD PMID:28404816 RGD:401900713 NCBI chr13:35,169,243...35,230,252
Ensembl chr13:35,180,912...35,268,577 		JBrowse link
G AKAP5 A-kinase anchoring protein 5 acts_upstream_of_or_within ISO (PMID:23259949) MGI PMID:23259949 NCBI chr 8:38,891,637...38,902,390
Ensembl chr 8:38,896,840...38,898,126 		JBrowse link
G AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) involved_in ISO (PMID:22170488) UniProt PMID:22170488 NCBI chr 2:30,661,333...30,691,283
Ensembl chr 2:30,674,558...30,690,043 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase involved_in ISO (PMID:17052953) UniProt PMID:17052953 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein involved_in ISO (PMID:2300173) UniProt PMID:2300173 NCBI chr25:9,320,868...9,351,056
Ensembl chr25:9,320,864...9,351,836 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein involved_in IEA Ensembl GO_REF:0000107
G ASPH aspartate beta-hydroxylase involved_in ISO (PMID:21062895) UniProt PMID:21062895 NCBI chr29:11,812,275...12,022,755
Ensembl chr29:11,814,554...12,022,680 		JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:8,222,909...8,318,179
Ensembl chr16:8,222,907...8,317,906 		JBrowse link
G CACYBP calcyclin binding protein ISO RGD PMID:11927578 RGD:625428 NCBI chr 7:24,372,599...24,384,084
Ensembl chr 7:24,372,596...24,383,926 		JBrowse link
G CAPN3 calpain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:9,329,190...9,384,622
Ensembl chr30:9,329,015...9,383,772 		JBrowse link
G CARF calcium responsive transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:11,786,976...11,884,644
Ensembl chr37:11,787,078...11,848,893 		JBrowse link
G CHP2 calcineurin like EF-hand protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:22,127,422...22,129,637 JBrowse link
G CLIC4 chloride intracellular channel 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,903,653...74,974,103
Ensembl chr 2:74,906,948...74,974,032 		JBrowse link
G CPNE1 copine 1 involved_in ISO (PMID:14674885) UniProt PMID:14674885 NCBI chr24:24,554,636...24,589,748
Ensembl chr24:24,554,636...24,589,731 		JBrowse link
G CPNE2 copine 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:59,226,410...59,257,170
Ensembl chr 2:59,226,410...59,259,900 		JBrowse link
G CPNE3 copine 3 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr29:32,682,019...32,736,871
Ensembl chr29:32,695,714...32,727,950 		JBrowse link
G CPNE4 copine 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr23:28,621,511...29,077,743
Ensembl chr23:28,622,845...29,077,642 		JBrowse link
G CPNE5 copine 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:5,812,460...5,902,467
Ensembl chr12:5,811,503...5,910,343 		JBrowse link
G CPNE6 copine 6 involved_in ISO (PMID:21087455) UniProt PMID:21087455 NCBI chr 8:4,078,240...4,084,744
Ensembl chr 8:4,046,544...4,084,744 		JBrowse link
G CPNE7 copine 7 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:63,951,547...63,978,389
Ensembl chr 5:63,951,549...63,978,601 		JBrowse link
G CPNE8 copine 8 involved_in IBA GO_Central GO_REF:0000033 NCBI chr27:14,620,300...14,938,470
Ensembl chr27:14,618,698...14,938,046 		JBrowse link
G CPNE9 copine family member 9 involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:8,511,267...8,529,630
Ensembl chr20:8,511,350...8,529,473 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein involved_in ISO (PMID:15976007) UniProt PMID:15976007 NCBI chr 3:29,726,316...29,737,748
Ensembl chr 3:29,705,031...29,758,111 		JBrowse link
G CRP C-reactive protein ISO RGD PMID:22090504 RGD:6904210 NCBI chr38:22,396,787...22,398,180
Ensembl chr38:22,396,263...22,399,166 		JBrowse link
G DPEP1 dipeptidase 1 involved_in ISO (PMID:11139399), (PMID:17615681) UniProt PMID:11139399 PMID:17615681 NCBI chr 5:63,909,034...63,923,309
Ensembl chr 5:63,909,042...63,923,492 		JBrowse link
G ECT2 epithelial cell transforming 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr34:36,897,441...36,958,501
Ensembl chr34:36,896,958...36,958,384 		JBrowse link
G EDN1 endothelin 1 ISO RGD PMID:1852000 RGD:8662267 NCBI chr35:11,808,892...11,815,383
Ensembl chr35:11,808,892...11,815,383 		JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase ISO RGD PMID:19188248 RGD:10401231 NCBI chr 6:23,368,296...23,433,853
Ensembl chr 6:23,371,546...23,433,929 		JBrowse link
G ENDOG endonuclease G ISO RGD PMID:12582256 RGD:9685368 NCBI chr 9:54,809,470...54,812,795
Ensembl chr 9:54,809,530...54,813,042 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19365557) Ensembl
MGI		 PMID:19365557 GO_REF:0000107 NCBI chr 8:48,330,856...48,334,273
Ensembl chr 8:48,331,026...48,333,467 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr 1:110,088,686...110,092,818
Ensembl chr 1:110,087,036...110,092,818 		JBrowse link
G FUS FUS RNA binding protein ISO RGD PMID:19103256 RGD:9685716 NCBI chr 6:17,059,904...17,071,227
Ensembl chr 6:17,060,061...17,071,178 		JBrowse link
G HPCA hippocalcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:68,464,631...68,473,661
Ensembl chr 2:68,465,280...68,473,310 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:9058202 RGD:11354978 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257 		JBrowse link
G INHBB inhibin subunit beta B ISO RGD PMID:1634019 RGD:9743923 NCBI chr19:29,765,697...29,768,485
Ensembl chr19:29,767,682...29,768,077 		JBrowse link
G IQGAP1 IQ motif containing GTPase activating protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,683,869...53,791,136
Ensembl chr 3:53,683,791...53,792,186 		JBrowse link
G ITPKA inositol-trisphosphate 3-kinase A involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:8,532,191...8,541,273
Ensembl chr30:8,532,284...8,541,285 		JBrowse link
G ITPKB inositol-trisphosphate 3-kinase B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,253,257...38,346,400
Ensembl chr 7:38,253,407...38,343,345 		JBrowse link
G ITPKC inositol-trisphosphate 3-kinase C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:113,037,833...113,053,877
Ensembl chr 1:113,039,093...113,053,738 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO (PMID:19303854) MGI PMID:19303854 NCBI chr 5:50,966,698...50,968,939 JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr20:49,358,904...49,360,746
Ensembl chr20:49,359,399...49,360,442 		JBrowse link
G JUND JunD proto-oncogene, AP-1 transcription factor subunit involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19303854) Ensembl
MGI		 PMID:19303854 GO_REF:0000107 NCBI chr20:44,737,021...44,738,932
Ensembl chr20:44,736,832...44,763,020 		JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 ISO RGD PMID:8978827 RGD:150527856 NCBI chr24:36,016,800...36,118,873
Ensembl chr24:36,025,472...36,117,934 		JBrowse link
G KCNH1 potassium voltage-gated channel subfamily H member 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:8790430 GO_REF:0000107 RGD:9693720 NCBI chr 7:9,317,804...9,631,144
Ensembl chr 7:9,252,488...9,631,150 		JBrowse link
G KCNQ2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO (PMID:23259949) MGI PMID:23259949 NCBI chr24:47,060,527...47,089,077
Ensembl chr24:47,060,245...47,089,711 		JBrowse link
G KCNQ3 potassium voltage-gated channel subfamily Q member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23259949) Ensembl
MGI		 PMID:23259949 GO_REF:0000107 NCBI chr13:28,765,472...29,062,371
Ensembl chr13:28,773,738...29,062,370 		JBrowse link
G KRT10 keratin 10 acts_upstream_of_or_within ISO (PMID:19303854) MGI PMID:19303854 NCBI chr 9:21,863,715...21,868,587
Ensembl chr 9:21,863,767...21,868,587 		JBrowse link
G LGMN legumain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:1,810,263...1,843,116
Ensembl chr 8:1,728,273...1,843,050 		JBrowse link
G LOC610636 tubulin alpha-1B chain involved_in ISO (PMID:27793670) MGI PMID:27793670 NCBI chr37:25,811,491...25,818,838 JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:52,318,411...52,327,389
Ensembl chr20:52,318,408...52,348,963 		JBrowse link
G MEF2A myocyte enhancer factor 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:41,012,103...41,177,588
Ensembl chr 3:41,015,713...41,179,448 		JBrowse link
G MEF2C myocyte enhancer factor 2C involved_in ISO (PMID:15998798) UniProt PMID:15998798 NCBI chr 3:19,778,997...19,948,203
Ensembl chr 3:19,779,007...19,943,852 		JBrowse link
G MICU1 mitochondrial calcium uptake 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:22,989,213...23,237,278
Ensembl chr 4:22,990,034...23,237,160 		JBrowse link
G MICU2 mitochondrial calcium uptake 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:16,726,766...16,854,590
Ensembl chr25:16,726,788...16,854,067 		JBrowse link
G MICU3 mitochondrial calcium uptake family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:40,362,572...40,457,665
Ensembl chr16:40,362,587...40,453,174 		JBrowse link
G MYLK myosin light chain kinase acts_upstream_of_or_within ISO (PMID:18524939) MGI PMID:18524939 NCBI chr33:26,663,991...26,867,370
Ensembl chr33:26,664,800...26,843,181 		JBrowse link
G NCSTN nicastrin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24889619) Ensembl
MGI		 PMID:24889619 GO_REF:0000107 NCBI chr38:21,878,071...21,891,362
Ensembl chr38:21,685,868...21,892,097 		JBrowse link
G NEUROD2 neuronal differentiation 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,864,708...22,869,044
Ensembl chr 9:22,866,212...22,867,360 		JBrowse link
G NFATC1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (PMID:23259949) MGI PMID:23259949 NCBI chr 1:1,027,021...1,121,362
Ensembl chr 1:1,028,695...1,121,588 		JBrowse link
G NFATC2 nuclear factor of activated T cells 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23259949) Ensembl
MGI		 PMID:23259949 GO_REF:0000107 NCBI chr24:37,606,977...37,734,813
Ensembl chr24:37,609,561...37,771,132 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 acts_upstream_of_or_within ISO (PMID:23219532) MGI PMID:23219532 NCBI chr 5:81,294,656...81,434,256
Ensembl chr 5:81,296,214...81,434,250 		JBrowse link
G NLGN1 neuroligin 1 involved_in ISO PMID:14522992 ARUK-UCL PMID:14522992 RGD:13210536 NCBI chr34:37,397,772...38,203,634
Ensembl chr34:37,572,629...38,203,177 		JBrowse link
G NRXN1 neurexin 1 involved_in ISO PMID:14522992 ARUK-UCL PMID:14522992 RGD:13210536 NCBI chr10:51,555,660...52,666,774
Ensembl chr10:51,558,452...52,667,569 		JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:11,383,441...11,437,603
Ensembl chr32:11,383,424...11,435,438 		JBrowse link
G PLCD1 phospholipase C delta 1 ISO RGD PMID:21767260 RGD:7349319 NCBI chr23:7,782,495...7,804,969
Ensembl chr23:7,781,787...7,805,336 		JBrowse link
G PLCG2 phospholipase C gamma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,054,683...70,233,459
Ensembl chr 5:70,059,255...70,207,049 		JBrowse link
G PPIF peptidylprolyl isomerase F involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:29,074,806...29,080,487 JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:18322138 RGD:8693423 NCBI chr11:22,388,327...22,410,052
Ensembl chr11:22,385,257...22,410,052 		JBrowse link
G PRKAA1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,579,061...68,614,548
Ensembl chr 4:68,579,037...68,611,841 		JBrowse link
G PRKAA2 protein kinase AMP-activated catalytic subunit alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:52,809,792...52,855,072
Ensembl chr 5:52,815,609...52,876,609 		JBrowse link
G RASA4B RAS p21 protein activator 4B involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:7,683,101...7,705,994 JBrowse link
G RASAL1 RAS protein activator like 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr26:10,503,309...10,532,217
Ensembl chr26:10,504,236...10,533,071 		JBrowse link
G RASGRP2 RAS guanyl releasing protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,412,331...52,426,910
Ensembl chr18:52,412,367...52,426,916 		JBrowse link
G SCN5A sodium voltage-gated channel alpha subunit 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:8,278,844...8,374,614
Ensembl chr23:8,280,793...8,358,560 		JBrowse link
G SLC25A23 solute carrier family 25 member 23 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23344948) Ensembl
MGI		 PMID:23344948 GO_REF:0000107 NCBI chr20:53,722,841...53,736,205
Ensembl chr20:53,722,320...53,733,331 		JBrowse link
G SLC25A24 solute carrier family 25 member 24 involved_in ISO (PMID:22015608) UniProt PMID:22015608 NCBI chr 6:43,424,079...43,476,861 JBrowse link
G SMPD1 sphingomyelin phosphodiesterase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:29,714,418...29,719,035
Ensembl chr21:29,714,557...29,719,033 		JBrowse link
G SYT1 synaptotagmin 1 involved_in ISO PMID:12526776 ParkinsonsUK-UCL PMID:12526776 RGD:10047386 NCBI chr15:21,629,061...22,042,734
Ensembl chr15:21,834,763...22,042,732 		JBrowse link
G TJP1 tight junction protein 1 involved_in IDA (PMID:8636221) UniProt PMID:8636221 NCBI chr 3:38,997,122...39,076,617
Ensembl chr 3:38,997,076...39,241,574 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:38,201,075...38,224,076 JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in ISO PMID:24803536 UniProt PMID:24803536 RGD:12910999 NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806 		JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:34,756,430...34,790,937
Ensembl chr20:34,769,930...34,786,673 		JBrowse link
cellular response to cobalt ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:23814049 RGD:11341692 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G BNIP3 BCL2 interacting protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:40,037,681...40,050,499
Ensembl chr28:40,038,643...40,049,797 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:15519734 RGD:8662904 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:10559391 RGD:2313660 NCBI chr 8:36,614,045...36,656,692
Ensembl chr 8:36,614,045...36,656,692 		JBrowse link
G SERPINF1 serpin family F member 1 ISO RGD PMID:21922517 RGD:8554899 NCBI chr 9:45,891,368...45,902,768
Ensembl chr 9:45,891,410...45,902,765 		JBrowse link
G TIGAR TP53 induced glycolysis regulatory phosphatase involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:40,521,751...40,549,304
Ensembl chr27:40,523,314...40,549,332 		JBrowse link
cellular response to copper ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APP amyloid beta precursor protein ISO RGD PMID:18583042 RGD:13782134 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G AQP1 aquaporin 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720 		JBrowse link
G AQP2 aquaporin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:4,743,127...4,750,907
Ensembl chr27:4,743,127...4,750,907 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:20671235 PMID:23174565 RGD:11341702 RGD:11341707 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G ATP7B ATPase copper transporting beta ISO RGD PMID:24614235 RGD:11341682 NCBI chr22:162,474...225,599
Ensembl chr22:191,888...225,266 		JBrowse link
G BACE1 beta-secretase 1 ISO RGD PMID:18583042 RGD:13782134 NCBI chr 5:16,308,953...16,319,100
Ensembl chr 5:16,308,944...16,319,100 		JBrowse link
G BECN1 beclin 1 ISO RGD PMID:22540380 RGD:11561917 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO RGD PMID:24599699 RGD:11352816 NCBI chr30:37,793,277...37,799,535
Ensembl chr30:37,793,508...37,796,866 		JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO RGD PMID:24599699 RGD:11352816 NCBI chr30:37,818,400...37,824,192
Ensembl chr30:37,799,140...37,824,135 		JBrowse link
G DAXX death domain associated protein involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:2,755,960...2,760,687
Ensembl chr12:2,755,960...2,761,340 		JBrowse link
G ELN elastin ISO RGD PMID:18847363 RGD:9585685 NCBI chr 6:6,299,524...6,331,425
Ensembl chr 6:6,300,727...6,331,325 		JBrowse link
G HSF1 heat shock transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252 		JBrowse link
G LOC100688390 metallothionein-2-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:46,319,153...46,319,335 JBrowse link
G LOC119877135 metallothionein-2-like involved_in IBA GO_Central GO_REF:0000033
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:22540380 RGD:11561917 NCBI chr24:23,672,343...23,673,937
Ensembl chr24:23,633,579...23,673,921 		JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G MT1E metallothionein 1E involved_in ISO (PMID:3403543) UniProt PMID:3403543
G MT4 metallothionein 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:59,640,784...59,643,370
Ensembl chr 2:59,640,784...59,643,370 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within ISO (PMID:24462598) MGI PMID:24462598 NCBI chr 9:24,344,697...24,356,918
Ensembl chr 9:24,346,585...24,362,646 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24462598) Ensembl
MGI		 PMID:24462598 GO_REF:0000107 NCBI chr36:20,989,205...21,087,044
Ensembl chr36:20,989,360...21,012,524 		JBrowse link
G PRNP prion protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16254249) MGI
Ensembl		 PMID:16254249 GO_REF:0000107 NCBI chr24:16,845,224...16,862,319
Ensembl chr24:16,846,207...16,859,815 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:12,915,871...13,079,338
Ensembl chr32:12,916,215...13,060,383 		JBrowse link
G TXNRD1 thioredoxin reductase 1 ISO RGD PMID:19781568 RGD:5130971 NCBI chr10:33,904,065...34,021,549
Ensembl chr10:33,886,343...34,021,696 		JBrowse link
cellular response to iron ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7A ATPase copper transporting alpha ISO RGD PMID:19679821 PMID:23174565 RGD:11341702 RGD:11341808 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:11,331,574...11,337,991
Ensembl chr30:11,331,569...11,337,997 		JBrowse link
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107
G BMP6 bone morphogenetic protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:24,031,479...24,038,922
Ensembl chr35:24,031,387...24,042,413 		JBrowse link
G LOC477072 serotransferrin involved_in ISO (PMID:18353247) BHF-UCL PMID:18353247 NCBI chr23:30,658,250...30,683,816
Ensembl chr23:30,595,704...30,683,845 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 ISO RGD PMID:17663481 RGD:5688717 NCBI chr27:3,788,785...3,823,852
Ensembl chr27:3,787,855...3,822,672 		JBrowse link
G SLC25A39 solute carrier family 25 member 39 involved_in ISO (PMID:37917749), (PMID:38157846) UniProt PMID:37917749 PMID:38157846 NCBI chr 9:19,103,104...19,107,691
Ensembl chr 9:19,102,787...19,107,694 		JBrowse link
G TFAP2A transcription factor AP-2 alpha involved_in ISO (PMID:20808827) UniProt PMID:20808827 NCBI chr35:10,157,043...10,180,484
Ensembl chr35:10,157,882...10,180,270 		JBrowse link
G TFR2 transferrin receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:9,059,501...9,076,646
Ensembl chr 6:9,060,629...9,076,158 		JBrowse link
cellular response to iron(II) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:19608791 RGD:10045561 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666 		JBrowse link
cellular response to iron(III) ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2M beta-2-microglobulin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9531620) Ensembl
MGI		 PMID:9531620 GO_REF:0000107 NCBI chr30:11,331,574...11,337,991
Ensembl chr30:11,331,569...11,337,997 		JBrowse link
G B2M beta-2-microglobulin involved_in IEA Ensembl GO_REF:0000107
G CCNB1 cyclin B1 ISO ferric ammonium citrate RGD PMID:18254965 RGD:2316320 NCBI chr 2:54,256,957...54,264,749 JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16135072 PMID:17469137 RGD:12904039 RGD:12904046 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:21683124 RGD:7207286 NCBI chr 5:28,978,385...28,986,644
Ensembl chr 5:28,978,473...28,986,648 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:21683124 RGD:7207286 NCBI chr24:33,274,260...33,281,116
Ensembl chr24:33,274,268...33,281,293 		JBrowse link
cellular response to lead ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase ISO lead, gallium RGD PMID:16566714 RGD:4144781 NCBI chr11:67,736,643...67,752,399
Ensembl chr11:67,741,390...67,752,321 		JBrowse link
G ANXA5 annexin A5 ISO RGD PMID:11578147 RGD:10053705 NCBI chr19:18,419,936...18,450,088
Ensembl chr19:18,407,587...18,570,378 		JBrowse link
G ATP7A ATPase copper transporting alpha ISO RGD PMID:24316150 RGD:11341684 NCBI chr  X:60,203,336...60,356,525
Ensembl chr  X:60,203,270...60,352,869 		JBrowse link
G CLDN1 claudin 1 ISO RGD PMID:17439918 RGD:11344879 NCBI chr34:22,303,058...22,319,101
Ensembl chr34:22,303,850...22,319,033 		JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:22764079 RGD:9588241 NCBI chr20:50,872,213...50,928,352
Ensembl chr20:50,879,527...50,928,029 		JBrowse link
G HMBS hydroxymethylbilane synthase ISO RGD PMID:16566714 RGD:4144781 NCBI chr 5:14,767,306...14,775,205
Ensembl chr 5:14,767,666...14,775,082 		JBrowse link
G HNRNPK heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:33576715 RGD:155582212 NCBI chr 1:75,499,334...75,511,525
Ensembl chr 1:75,499,393...75,511,425 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:25193092 RGD:13207490 NCBI chr 7:19,668,079...19,674,903
Ensembl chr 7:19,668,082...19,674,903 		JBrowse link
G UCP2 uncoupling protein 2 ISO RGD PMID:33576715 RGD:155582212 NCBI chr21:24,304,410...24,311,392
Ensembl chr21:24,304,457...24,311,128 		JBrowse link
cellular response to lithium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADCY7 adenylate cyclase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:65,003,891...65,034,812
Ensembl chr 2:65,006,038...65,034,777 		JBrowse link
G CALR calreticulin ISO RGD PMID:16236328 RGD:2326183 NCBI chr20:49,251,390...49,255,291
Ensembl chr20:49,251,777...49,255,245 		JBrowse link
G CDH1 cadherin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:80,757,508...80,834,878
Ensembl chr 5:80,757,508...80,834,878 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19056892) MGI
Ensembl		 PMID:19056892 GO_REF:0000107 NCBI chr27:33,609,154...33,613,558
Ensembl chr27:33,611,760...33,612,906 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha acts_upstream_of_or_within ISO (PMID:15673614) MGI PMID:15673614 NCBI chr 1:118,846,252...118,851,045 JBrowse link
G CTNNB1 catenin beta 1 ISO RGD PMID:12610652 RGD:10395276 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G FABP4 fatty acid binding protein 4 acts_upstream_of_or_within ISO (PMID:15673614) MGI PMID:15673614 NCBI chr29:28,651,550...28,656,255
Ensembl chr29:28,652,146...28,656,228 		JBrowse link
G FAS Fas cell surface death receptor acts_upstream_of_or_within ISO (PMID:20530871) MGI PMID:20530871 NCBI chr26:38,738,811...38,763,298
Ensembl chr26:38,737,611...38,763,321 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15673614) Ensembl
MGI		 PMID:15673614 GO_REF:0000107 NCBI chr 1:112,129,116...112,138,714
Ensembl chr 1:112,103,825...112,138,559 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta ISO RGD PMID:18932008 RGD:10045540 NCBI chr33:23,458,369...23,659,878
Ensembl chr33:23,463,767...23,659,666 		JBrowse link
G GSTA4 glutathione S-transferase alpha 4 ISO RGD PMID:18082333 RGD:2293846 NCBI chr12:20,426,724...20,443,200
Ensembl chr12:20,426,726...20,443,200 		JBrowse link
G LIG4 DNA ligase 4 ISO RGD PMID:19285016 RGD:2317095 NCBI chr22:56,980,333...56,987,636
Ensembl chr22:56,980,622...56,983,357 		JBrowse link
G LOC102151783 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO (PMID:18367557) MGI PMID:18367557 NCBI chr10:54,954,852...54,957,116 JBrowse link
G MYOG myogenin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15673614) Ensembl
MGI		 PMID:15673614 GO_REF:0000107 NCBI chr 7:112,116...114,604
Ensembl chr 7:112,034...113,892 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 acts_upstream_of_or_within ISO (PMID:20530871) MGI PMID:20530871 NCBI chr 5:81,294,656...81,434,256
Ensembl chr 5:81,296,214...81,434,250 		JBrowse link
G NFATC4 nuclear factor of activated T cells 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20530871) Ensembl
MGI		 PMID:20530871 GO_REF:0000107 NCBI chr 8:4,337,098...4,346,409
Ensembl chr 8:4,336,450...4,346,100 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:21994254 RGD:5508722 NCBI chr 9:42,171,821...42,210,217
Ensembl chr 9:42,171,821...42,208,588 		JBrowse link
G NTS neurotensin ISO RGD PMID:7898306 RGD:9743905 NCBI chr15:27,361,002...27,372,232
Ensembl chr15:27,361,002...27,372,232 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma acts_upstream_of_or_within ISO (PMID:15673614) MGI PMID:15673614 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17284610) Ensembl
MGI		 PMID:17284610 GO_REF:0000107 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903 		JBrowse link
G SLC13A2 solute carrier family 13 member 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:42,689,296...42,713,209
Ensembl chr 9:42,688,468...42,712,678 		JBrowse link
G SLC13A5 solute carrier family 13 member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:30,655,167...30,677,551
Ensembl chr 5:30,655,760...30,674,653 		JBrowse link
G SLC18A1 solute carrier family 18 member A1 ISO RGD PMID:11080216 RGD:5131196 NCBI chr25:36,859,047...36,904,057
Ensembl chr25:36,872,636...36,904,056 		JBrowse link
G TPH2 tryptophan hydroxylase 2 ISO RGD PMID:19840776 RGD:2317083 NCBI chr10:13,442,611...13,526,537
Ensembl chr10:13,442,611...13,527,243 		JBrowse link
G XRCC4 X-ray repair cross complementing 4 ISO RGD PMID:19285016 RGD:2317095 NCBI chr 3:24,316,598...24,547,463
Ensembl chr 3:24,269,974...24,533,465 		JBrowse link
cellular response to magnesium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANK3 ankyrin 3 involved_in ISO (PMID:23903368) UniProt PMID:23903368 NCBI chr 4:12,166,275...12,827,175
Ensembl chr 4:12,167,550...12,827,037 		JBrowse link
G AZGP1 alpha-2-glycoprotein 1, zinc-binding ISO RGD PMID:30950934 RGD:153350153 NCBI chr 6:9,622,991...9,629,154
Ensembl chr 6:9,622,992...9,629,154 		JBrowse link
G FBP1 fructose-bisphosphatase 1 involved_in ISO (PMID:10222032) UniProt PMID:10222032 NCBI chr 1:72,099,886...72,125,266
Ensembl chr 1:72,099,881...72,125,224 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19154422 RGD:2326036 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960 		JBrowse link
G KCNA1 potassium voltage-gated channel subfamily A member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:39,928,347...39,936,753
Ensembl chr27:39,933,825...39,935,312 		JBrowse link
G KCNJ1 potassium inwardly rectifying channel subfamily J member 1 ISO RGD PMID:21030597 RGD:7244391 NCBI chr 5:5,783,242...5,813,961
Ensembl chr 5:5,809,118...5,812,794 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO RGD PMID:15919495 RGD:7794721 NCBI chr16:15,054,196...15,072,454
Ensembl chr16:15,011,344...15,072,277 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO RGD PMID:20350433 RGD:4892212 NCBI chr 2:38,124,568...38,242,510
Ensembl chr 2:38,123,190...38,240,755 		JBrowse link
G SLC41A1 solute carrier family 41 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:2,216,378...2,239,303
Ensembl chr38:2,218,706...2,236,672 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23973266) Ensembl
MGI		 PMID:23973266 GO_REF:0000107 NCBI chr 5:81,089,657...81,172,173
Ensembl chr 5:81,142,888...81,172,189 		JBrowse link
cellular response to manganese ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A3GALT2 alpha 1,3-galactosyltransferase 2 ISO RGD PMID:1569388 RGD:13831122 NCBI chr 2:68,117,648...68,138,610
Ensembl chr 2:68,118,413...68,138,095 		JBrowse link
G APP amyloid beta precursor protein ISO RGD PMID:18583042 RGD:13782134 NCBI chr31:21,351,207...21,614,466
Ensembl chr31:21,351,207...21,614,337 		JBrowse link
G ATP13A2 ATPase cation transporting 13A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:81,196,355...81,215,736
Ensembl chr 2:81,196,463...81,215,689 		JBrowse link
G ATP7B ATPase copper transporting beta ISO RGD PMID:24614235 RGD:11341682 NCBI chr22:162,474...225,599
Ensembl chr22:191,888...225,266 		JBrowse link
G BACE1 beta-secretase 1 ISO RGD PMID:18583042 RGD:13782134 NCBI chr 5:16,308,953...16,319,100
Ensembl chr 5:16,308,944...16,319,100 		JBrowse link
G CASP12 caspase 12 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 5:27,162,840...27,176,964
Ensembl chr 5:27,161,700...27,177,683 		JBrowse link
G DBH dopamine beta-hydroxylase ISO RGD PMID:19276553 RGD:5129515 NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr10:1,606,693...1,612,410
Ensembl chr10:1,606,693...1,611,303 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 9:11,930,614...12,006,724
Ensembl chr 9:11,934,965...12,006,814 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO RGD PMID:19643132 RGD:2325970 NCBI chr 9:48,492,967...48,513,981
Ensembl chr 9:48,493,287...48,509,050 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19643132 RGD:2325970 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B ISO RGD PMID:19643132 RGD:2325970 NCBI chr27:32,470,889...32,883,606
Ensembl chr27:32,471,153...32,877,680 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr15:42,456,793...42,474,122
Ensembl chr15:42,456,764...42,579,311 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 9:57,850,870...57,855,607
Ensembl chr 9:57,850,922...57,855,257 		JBrowse link
G IREB2 iron responsive element binding protein 2 ISO RGD PMID:16568477 PMID:17469137 RGD:12904039 RGD:12904041 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870 		JBrowse link
G MFN2 mitofusin 2 ISO RGD PMID:28232070 RGD:12910738 NCBI chr 2:84,284,719...84,310,715
Ensembl chr 2:84,284,719...84,308,225 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:19781568 RGD:5130971 NCBI chr 1:49,886,887...51,201,930
Ensembl chr 1:49,889,005...51,201,764 		JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:19781568 RGD:5130971 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602 		JBrowse link
cellular response to mercury ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720 		JBrowse link
G AQP2 aquaporin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:4,743,127...4,750,907
Ensembl chr27:4,743,127...4,750,907 		JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:11768240 RGD:729934 NCBI chr37:22,456,854...22,522,410
Ensembl chr37:22,420,428...22,523,123 		JBrowse link
G IL4 interleukin 4 ISO RGD PMID:7657819 PMID:19604304 RGD:2317279 RGD:2317674 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534 		JBrowse link
G NOX1 NADPH oxidase 1 ISO RGD PMID:28935286 RGD:329961577 NCBI chr  X:74,784,627...74,811,796
Ensembl chr  X:74,785,168...74,811,698 		JBrowse link
G NOX4 NADPH oxidase 4 ISO RGD PMID:28935286 RGD:329961577 NCBI chr21:10,615,153...10,782,927
Ensembl chr21:10,615,970...10,775,277 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15635608) Ensembl
MGI		 PMID:15635608 GO_REF:0000107 NCBI chr 1:92,898,274...92,978,260
Ensembl chr 1:92,898,274...92,978,260 		JBrowse link
G UBE2D3 ubiquitin conjugating enzyme E2 D3 ISO RGD PMID:24212999 RGD:13830869 NCBI chr32:24,190,897...24,221,627 JBrowse link
cellular response to potassium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC9 ATP binding cassette subfamily C member 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:20935152) MGI
Ensembl		 PMID:20935152 GO_REF:0000107 NCBI chr27:25,199,580...25,352,637
Ensembl chr27:25,200,418...25,388,477 		JBrowse link
G ACTA1 actin alpha 1, skeletal muscle ISO RGD PMID:17146758 RGD:1598717 NCBI chr 4:9,811,726...9,814,533
Ensembl chr 4:9,811,801...9,814,530 		JBrowse link
G BDNF brain derived neurotrophic factor ISO RGD PMID:25424568 RGD:11060597 NCBI chr21:48,191,580...48,243,699
Ensembl chr21:48,192,670...48,204,480 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:39,510,129...39,533,129
Ensembl chr 6:39,510,121...39,533,753 		JBrowse link
G CRHBP corticotropin releasing hormone binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:29,726,316...29,737,748
Ensembl chr 3:29,705,031...29,758,111 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 involved_in ISO (PMID:19342457) UniProt PMID:19342457 NCBI chr13:36,866,476...36,880,625 JBrowse link
G DLG2 discs large MAGUK scaffold protein 2 involved_in ISO (PMID:26609151) ARUK-UCL PMID:26609151 NCBI chr21:13,796,725...15,776,601
Ensembl chr21:13,822,304...15,771,954 		JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,165,399...32,175,600
Ensembl chr 5:32,163,594...32,188,126 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 ISO RGD PMID:15028757 RGD:1300188 NCBI chr  X:116,249,079...116,287,008
Ensembl chr  X:116,249,142...116,321,439 		JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 ISO RGD PMID:17298175 RGD:10045993 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891 		JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:24478344 RGD:10402566 NCBI chr13:37,724,741...37,745,259
Ensembl chr13:37,724,759...37,745,252 		JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 involved_in ISO (PMID:31736353) MGI PMID:31736353 NCBI chr38:22,114,718...22,143,625
Ensembl chr38:22,130,508...22,140,813 		JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:14593183 RGD:12790707 NCBI chr  X:121,866,721...121,876,088
Ensembl chr  X:121,873,218...121,932,994 		JBrowse link
G MYLK myosin light chain kinase acts_upstream_of_or_within ISO (PMID:18524939) MGI PMID:18524939 NCBI chr33:26,663,991...26,867,370
Ensembl chr33:26,664,800...26,843,181 		JBrowse link
G NEK7 NIMA related kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:4,557,754...4,755,912
Ensembl chr 7:4,555,231...4,704,955 		JBrowse link
G NPTX1 neuronal pentraxin 1 ISO RGD PMID:22279230 RGD:6903322 NCBI chr 9:1,388,728...1,398,115
Ensembl chr 9:1,388,407...1,399,390 		JBrowse link
G NRG1 neuregulin 1 ISO RGD PMID:26043693 RGD:405650602 NCBI chr16:31,697,958...32,771,888
Ensembl chr16:31,706,851...32,771,932 		JBrowse link
G PPARGC1A PPARG coactivator 1 alpha ISO RGD PMID:17870059 RGD:10059655 NCBI chr 3:85,645,942...86,284,570
Ensembl chr 3:86,016,140...86,281,269 		JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:21596853 RGD:8547918 NCBI chr 6:8,719,547...8,727,160
Ensembl chr 6:8,720,825...8,726,301 		JBrowse link
G SLC12A2 solute carrier family 12 member 2 involved_in ISO (PMID:11940530) ARUK-UCL PMID:11940530 NCBI chr11:17,143,943...17,256,248
Ensembl chr11:17,143,943...17,253,695 		JBrowse link
G SOD1 superoxide dismutase 1 ISO RGD PMID:17403136 RGD:8657024 NCBI chr31:26,540,291...26,544,212
Ensembl chr31:26,486,274...26,662,815 		JBrowse link
G STK39 serine/threonine kinase 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:12,866,867...13,118,736
Ensembl chr36:12,867,188...13,183,160 		JBrowse link
cellular response to zinc ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREB1 cAMP responsive element binding protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23716681) Ensembl
MGI		 PMID:23716681 GO_REF:0000107 NCBI chr37:15,921,214...15,978,492
Ensembl chr37:15,939,138...15,977,556 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 acts_upstream_of_or_within ISO (PMID:12183328) MGI PMID:12183328 NCBI chr 3:33,878,948...34,101,987
Ensembl chr 3:33,878,904...34,097,764 		JBrowse link
G GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 ISO RGD PMID:20371809 RGD:402464051 NCBI chr 4:48,794,770...48,901,859
Ensembl chr 4:48,796,852...48,901,548 		JBrowse link
G GLRA1 glycine receptor alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:57,443,094...57,541,494
Ensembl chr 4:57,443,999...57,528,376 		JBrowse link
G GLRA2 glycine receptor alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:10,859,699...11,033,386
Ensembl chr  X:10,860,476...11,033,287 		JBrowse link
G GLRA3 glycine receptor alpha 3 involved_in ISO PMID:23895467 UniProt PMID:23895467 RGD:11035333 NCBI chr25:25,098,280...25,305,511
Ensembl chr25:25,131,250...25,305,027 		JBrowse link
G GPR39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (PMID:23133519)
(PMID:26375174)		 MGI PMID:23133519 PMID:26375174 NCBI chr19:35,385,835...35,585,953
Ensembl chr19:35,385,829...35,586,507 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO RGD PMID:19240037 RGD:2326029 NCBI chr 6:32,132,070...32,678,319
Ensembl chr 6:32,303,121...32,668,960 		JBrowse link
G HVCN1 hydrogen voltage gated channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:8,437,032...8,474,831
Ensembl chr26:8,419,269...8,466,523 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 ISO RGD PMID:9437008 RGD:61647 NCBI chr17:20,732,779...20,771,104
Ensembl chr17:20,732,819...20,768,730 		JBrowse link
G LOC100686073 metallothionein-1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:18605988) UniProt
MGI		 PMID:18605988 GO_REF:0000024 NCBI chr 2:59,603,021...59,604,173
Ensembl chr 2:59,603,014...59,604,132 		JBrowse link
G LOC100687870 metallothionein-2-like involved_in ISO (PMID:8119276) UniProt PMID:8119276 NCBI chr 5:27,798,985...27,799,174 JBrowse link
G LOC100688390 metallothionein-2-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:46,319,153...46,319,335 JBrowse link
G LOC119876467 metallothionein-1 involved_in ISS UniProt GO_REF:0000024
G LOC119877135 metallothionein-2-like involved_in IBA GO_Central GO_REF:0000033
G LOC491382 zinc finger protein 658 involved_in ISO (PMID:25582195) UniProt PMID:25582195 NCBI chr 1:69,663,288...69,691,171 JBrowse link
G MT-III transcription initiation factor TFIID subunit 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:59,624,845...59,630,386 JBrowse link
G MT1E metallothionein 1E involved_in ISS UniProt GO_REF:0000024
G MT2A metallothionein 1H involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:59,607,926...59,608,825
Ensembl chr 2:59,607,927...59,626,727 		JBrowse link
G MT4 metallothionein 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:59,640,784...59,643,370
Ensembl chr 2:59,640,784...59,643,370 		JBrowse link
G MTF1 metal regulatory transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:4,679,945...4,723,111
Ensembl chr15:4,680,372...4,717,561 		JBrowse link
G P2RX4 purinergic receptor P2X 4 involved_in ISO PMID:8551329 UniProt PMID:8551329 RGD:61682 NCBI chr26:7,897,528...7,914,279
Ensembl chr26:7,898,015...7,914,234 		JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 ISO RGD PMID:23582235 RGD:10414068 NCBI chr 7:38,503,072...38,542,556
Ensembl chr 7:38,503,067...38,542,127 		JBrowse link
G TSPO translocator protein ISO RGD PMID:18709649 RGD:2317141 NCBI chr10:22,388,498...22,399,329
Ensembl chr10:22,274,405...22,399,297 		JBrowse link
response to manganese-induced endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr10:25,528,880...25,531,018
Ensembl chr10:25,528,874...25,530,993 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr17:37,886,397...37,950,671
Ensembl chr17:37,886,601...37,949,812 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha involved_in ISO PMID:23934647 ParkinsonsUK-UCL PMID:23934647 RGD:10047151 NCBI chr 8:41,354,400...41,371,676
Ensembl chr 8:41,351,244...41,371,056 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22103
    response to stimulus 9553
      response to chemical 5158
        response to metal ion 519
          cellular response to metal ion 253
            cellular response to aluminum ion 2
            cellular response to cadmium ion + 31
            cellular response to calcium ion + 87
            cellular response to cesium ion 0
            cellular response to cobalt ion 6
            cellular response to copper ion + 23
            cellular response to iron ion + 15
            cellular response to lead ion 9
            cellular response to lithium ion 25
            cellular response to magnesium ion 10
            cellular response to manganese ion + 22
            cellular response to mercury ion 8
            cellular response to nickel ion 0
            cellular response to platinum ion 0
            cellular response to potassium ion + 22
            cellular response to selenium ion 0
            cellular response to silver ion 0
            cellular response to tellurium ion 0
            cellular response to zinc ion 24
paths to the root