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ONTOLOGY REPORT - ANNOTATIONS

Term:WASH complex
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Accession:GO:0071203 term browser browse the term
Definition:A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.


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WASH complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 part_of ISO
ISS		 (PMID:19922875)
GO_REF:0000024		 RGD
UniProt		 PMID:19922875 GO_REF:0000024 NCBI chr 2:192,319,696...192,364,755
Ensembl chr 2:192,319,702...192,364,480 		JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta part_of ISO
ISS
IEA		 (PMID:19922875)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19922875 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:151,435,600...151,535,409
Ensembl chr 5:151,434,871...151,535,409 		JBrowse link
G Dnajc13 DnaJ heat shock protein family (Hsp40) member C13 located_in ISO (PMID:24643499) RGD PMID:24643499 NCBI chr 8:104,767,785...104,877,317
Ensembl chr 8:104,767,788...104,877,317 		JBrowse link
G Rcsd1 RCSD domain containing 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr13:77,901,898...77,964,309
Ensembl chr13:77,901,898...77,966,228 		JBrowse link
G Snx27 sorting nexin 27 part_of
located_in		 IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:21602791), (PMID:23563491)		 Ensembl
UniProt
RGD		 PMID:21602791 PMID:23563491 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906 		JBrowse link
G Tbc1d23 TBC1 domain family, member 23 located_in
part_of		 ISO (PMID:29084197) RGD PMID:29084197 NCBI chr11:43,303,355...43,361,507
Ensembl chr11:43,303,355...43,361,503 		JBrowse link
G Washc1 WASH complex subunit 1 part_of ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:19922875)
GO_REF:0000002
GO_REF:0000033
(PMID:26965651), (PMID:27390154)		 UniProt
RGD
InterPro
GO_Central		 PMID:19922875 PMID:26965651 PMID:27390154 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 NCBI chr 9:105,722,779...105,830,836
Ensembl chr 9:105,722,899...105,733,009 		JBrowse link
G Washc1-ps2 WASH complex subunit 1, pseudogene 2 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:106,097,337...106,103,219
Ensembl chr 9:106,097,498...106,100,342
Ensembl chr 9:106,097,498...106,100,342 		JBrowse link
G Washc2c WASH complex subunit 2C part_of ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:19922875)
GO_REF:0000107
GO_REF:0000033
(PMID:27390154)		 UniProt
RGD
Ensembl
GO_Central		 PMID:19922875 PMID:27390154 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:149,267,851...149,325,850
Ensembl chr 4:149,267,924...149,325,851 		JBrowse link
G Washc3 WASH complex subunit 3 part_of ISO
IBA		 (PMID:19922875)
GO_REF:0000033
(PMID:27390154)		 RGD
GO_Central		 PMID:19922875 PMID:27390154 GO_REF:0000033 NCBI chr 7:22,621,078...22,665,550
Ensembl chr 7:22,621,078...22,690,696 		JBrowse link
G Washc4 WASH complex subunit 4 part_of ISO
IBA		 (PMID:19922875)
GO_REF:0000033
(PMID:27390154)		 RGD
GO_Central		 PMID:19922875 PMID:27390154 GO_REF:0000033 NCBI chr 7:20,187,905...20,240,228
Ensembl chr 7:20,187,922...20,240,226 		JBrowse link
G Washc5 WASH complex subunit 5 part_of ISO
IBA		 (PMID:19922875)
GO_REF:0000033
(PMID:27390154)		 RGD
GO_Central		 PMID:19922875 PMID:27390154 GO_REF:0000033 NCBI chr 7:90,884,192...90,936,096
Ensembl chr 7:90,884,197...90,936,103 		JBrowse link
G Wipf3 WAS/WASL interacting protein family, member 3 part_of IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:83,550,075...83,629,929
Ensembl chr 4:83,550,468...83,629,386 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20833
    protein-containing complex 6558
      WASH complex 13
Path 2
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      intracellular anatomical structure 15189
        cytoplasm 11893
          WASH complex 13
paths to the root