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ONTOLOGY REPORT - ANNOTATIONS


Term:nuclear pore transmembrane ring
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Accession:GO:0070762 term browser browse the term
Definition:A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.
Synonyms:exact_synonym: NDC1 complex;   NDC1 subcomplex



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nuclear pore transmembrane ring term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndc1 NDC1 transmembrane nucleoporin part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:122,155,992...122,202,295
Ensembl chr 5:122,155,967...122,202,291
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Path 1
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  cellular_component 20824
    protein-containing complex 6552
      nuclear protein-containing complex 1279
        nuclear pore transmembrane ring 1
Path 2
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  cellular_component 20824
    cellular anatomical structure 20625
      organelle 13967
        membrane-bounded organelle 12555
          intracellular membrane-bounded organelle 12003
            nucleus 7451
              nuclear protein-containing complex 1279
                nuclear pore 78
                  nuclear pore transmembrane ring 1
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