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ONTOLOGY REPORT - ANNOTATIONS

Term:FHF complex
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Accession:GO:0070695 term browser browse the term
Definition:A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
Comment:Note that the gene/protein name 'APC' should not be confused with the abbreviation for 'anaphase promoting complex'.


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FHF complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aktip AKT interacting protein part_of ISS
ISO
IEA		 GO_REF:0000024
(PMID:18799622), (PMID:32073997)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18799622 PMID:32073997 GO_REF:0000024 GO_REF:0000107 NCBI chr19:15,866,811...15,877,123
Ensembl chr19:15,866,928...15,886,663 		JBrowse link
G Fhip1b FHF complex subunit HOOK interacting protein 1B part_of ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:18799622), (PMID:32073997)
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:18799622 PMID:32073997 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:159,718,679...159,748,449
Ensembl chr 1:159,726,004...159,748,408 		JBrowse link
G Hook1 hook microtubule-tethering protein 1 part_of ISO (PMID:18799622), (PMID:32073997) RGD PMID:18799622 PMID:32073997 NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787 		JBrowse link
G Hook2 hook microtubule-tethering protein 2 part_of ISO (PMID:18799622), (PMID:32073997) RGD PMID:18799622 PMID:32073997 NCBI chr19:23,151,869...23,170,139
Ensembl chr19:23,151,870...23,164,181 		JBrowse link
G Hook3 hook microtubule-tethering protein 3 part_of ISO (PMID:18799622), (PMID:32073997) RGD PMID:18799622 PMID:32073997 NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20833
    protein-containing complex 6558
      FHF complex 5
Path 2
Term Annotations click to browse term
  cellular_component 20833
    cellular anatomical structure 20633
      intracellular anatomical structure 15189
        cytoplasm 11893
          FHF complex 5
paths to the root