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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of ERK1 and ERK2 cascade
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Accession:GO:0070374 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
Synonyms:exact_synonym: positive regulation of ERK1 and ERK2 signaling pathway;   positive regulation of ERK1 and ERK2 signalling pathway;   positive regulation of ERK1/2 cascade;   up regulation of ERK1 and ERK2 cascade;   upregulation of ERK1 and ERK2 cascade
 narrow_synonym: activation of ERK1 and ERK2 cascade;   positive regulation of ERK1 cascade;   positive regulation of ERK2 cascade;   positive regulation of MAPK1 cascade;   positive regulation of MAPK3 cascade;   stimulation of ERK1 and ERK2 cascade
 broad_synonym: positive regulation of ERK cascade


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positive regulation of ERK1 and ERK2 cascade term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16908670)		 Alzheimers_University_of_Toronto
RGD		 PMID:16908670 GO_REF:0000024 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:18827006) RGD PMID:18827006 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Abl2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO MGI:99511 (PMID:18827006) RGD PMID:18827006 NCBI chr13:68,673,702...68,770,846
Ensembl chr13:68,673,722...68,839,742 		JBrowse link
G Ackr3 atypical chemokine receptor 3 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1341264|MGI:95294|MGI:98397 (PMID:22956548)
(PMID:22300987)		 UniProt
RGD		 PMID:22300987 PMID:22956548 GO_REF:0000024 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Acta2 actin alpha 2, smooth muscle IMP RGD PMID:24204762 RGD:12879446 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 involved_in IMP
ISO		 (PMID:23389627) RGD PMID:23389627 PMID:23688779 RGD:13703057 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 involved_in ISO
IBA
IDA		 (PMID:23800469)
GO_REF:0000033		 RGD
GO_Central		 PMID:23800469 PMID:23800469 GO_REF:0000033, RGD:8554519 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Adora2a adenosine A2a receptor IDA RGD PMID:15211592 RGD:1625666 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adra1a adrenoceptor alpha 1A involved_in IMP PMID:19011682 BHF-UCL PMID:19011682 RGD:5688340 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Ager advanced glycosylation end product-specific receptor involved_in ISO
IEA		 UniProtKB:P05067 (PMID:15457210)
GO_REF:0000107		 RGD
Ensembl		 PMID:15457210 GO_REF:0000107 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Akap12 A-kinase anchoring protein 12 IMP RGD PMID:19937403 RGD:14348968 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Alkal1 ALK and LTK ligand 1 involved_in ISO
IBA		 (PMID:26418745)
GO_REF:0000033		 RGD
GO_Central		 PMID:26418745 GO_REF:0000033 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948 		JBrowse link
G Alkal2 ALK and LTK ligand 2 involved_in ISO
IBA		 (PMID:26418745)
GO_REF:0000033		 RGD
GO_Central		 PMID:26418745 GO_REF:0000033 NCBI chr 6:47,495,645...47,505,235
Ensembl chr 6:47,495,782...47,505,234 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in ISO
ISS		 (PMID:21831839)
GO_REF:0000024		 RGD
UniProt		 PMID:21831839 GO_REF:0000024 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Angpt1 angiopoietin 1 involved_in
acts_upstream_of_or_within_positive_effect		 IEA
ISO		 GO_REF:0000107
(PMID:18425120)
(PMID:19615361)		 Ensembl
RGD		 PMID:18425120 PMID:19615361 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Apela apelin receptor early endogenous ligand involved_in IMP PMID:26611206 UniProt PMID:26611206 RGD:11534624 NCBI chr16:24,694,356...24,703,466
Ensembl chr16:24,694,324...24,703,465 		JBrowse link
G Apoe apolipoprotein E involved_in IEA
ISO		 GO_REF:0000107
(PMID:28111074)		 Ensembl
RGD		 PMID:28111074 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G App amyloid beta precursor protein involved_in IGI
ISO
IEA
IDA		 PMID:11404397
UniProtKB:P25090|UniProtKB:Q9UEW3 (PMID:18723082), (PMID:20141570)
GO_REF:0000107
UniProtKB:Q15109 (PMID:15457210)		 RGD
Ensembl		 PMID:15457210 PMID:18723082 PMID:20141570 PMID:11404397 PMID:11404397 GO_REF:0000107, RGD:12790656, RGD:12790656 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arhgap8 Rho GTPase activating protein 8 involved_in ISO (PMID:20179103) RGD PMID:20179103 NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093 		JBrowse link
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) RGD PMID:23389627 NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355 		JBrowse link
G Arrb1 arrestin, beta 1 involved_in IMP
ISO
IBA		 (PMID:19915011)
GO_REF:0000033
(PMID:10644702)		 RGD
GO_Central		 PMID:10644702 PMID:19915011 PMID:19289825 GO_REF:0000033, RGD:5509998 NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061 		JBrowse link
G Arrb2 arrestin, beta 2 involved_in IMP
IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
(PMID:10644702), (PMID:12582207)		 GO_Central
Ensembl
RGD		 PMID:10644702 PMID:12582207 PMID:19171933 PMID:19014370 PMID:19254952 More... GO_REF:0000033 GO_REF:0000107, RGD:5510006, RGD:401938609, RGD:5509898, RGD:13506828 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C IMP RGD PMID:17845832 RGD:14700553 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA		 (PMID:19664780), (PMID:22540193)
GO_REF:0000107		 RGD
Ensembl		 PMID:19664780 PMID:22540193 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18692041)		 Ensembl
RGD		 PMID:18692041 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmper BMP-binding endothelial regulator involved_in ISO (PMID:18787191) RGD PMID:18787191 NCBI chr 8:21,732,225...21,977,261
Ensembl chr 8:21,732,225...21,977,256 		JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase acts_upstream_of_or_within
involved_in		 IMP
ISO		 MGI:1857579|MGI:3620008|MGI:3622450|MGI:3711006 (PMID:15199148), (PMID:15784729), (PMID:16342120), (PMID:18228248), (PMID:22892241), (PMID:23334952), (PMID:23616533)
(PMID:22065586)		 RGD PMID:15199148 PMID:15784729 PMID:16342120 PMID:18228248 PMID:22065586 More... RGD:2315869 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463 		JBrowse link
G C1qtnf3 C1q and TNF related 3 acts_upstream_of_or_within ISO (PMID:20952387) RGD PMID:20952387 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433 		JBrowse link
G C3 complement C3 IDA RGD PMID:18178156 RGD:5129534 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C5ar1 complement C5a receptor 1 involved_in ISO
ISS		 (PMID:22496247)
GO_REF:0000024		 RGD
UniProt		 PMID:22496247 GO_REF:0000024 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Calcr calcitonin receptor involved_in ISO
IEA		 UniProtKB:O60896|UniProtKB:P05067-PRO_0000000092 (PMID:22500019)
GO_REF:0000107		 RGD
Ensembl		 PMID:22500019 GO_REF:0000107 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta IMP RGD PMID:18385282 RGD:6907067 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Card9 caspase recruitment domain family, member 9 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25267792)		 UniProt
RGD		 PMID:25267792 GO_REF:0000024 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casr calcium-sensing receptor IDA RGD PMID:22192592 RGD:7207059 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811 		JBrowse link
G Cavin3 caveolae associated protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:5518819 (PMID:24069528)		 Ensembl
RGD		 PMID:24069528 GO_REF:0000107 NCBI chr 1:159,826,549...159,828,138
Ensembl chr 1:159,826,549...159,828,161 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO UniProtKB:O00182 (PMID:15778365), (PMID:25754930) RGD PMID:15778365 PMID:25754930 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 involved_in ISO (PMID:12729902), (PMID:15778365) RGD PMID:12729902 PMID:15778365 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 involved_in ISO
ISS		 (PMID:21403648)
GO_REF:0000024		 RGD
UniProt		 PMID:21403648 GO_REF:0000024 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccn2 cellular communication network factor 2 involved_in ISO
IEA		 (PMID:20008146)
GO_REF:0000107		 RGD
Ensembl		 PMID:20008146 GO_REF:0000107 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 involved_in ISO (PMID:21403648) RGD PMID:21403648 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr1l1 chemokine (C-C motif) receptor 1-like 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:123,589,997...123,613,767
Ensembl chr 8:123,589,621...123,612,687 		JBrowse link
G Cd36 CD36 molecule involved_in IEA
ISO		 GO_REF:0000107
(PMID:21610069)		 Ensembl
RGD		 PMID:21610069 GO_REF:0000107 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd4 Cd4 molecule involved_in ISO
IEA		 (PMID:24942581)
GO_REF:0000107		 RGD
Ensembl		 PMID:24942581 GO_REF:0000107 NCBI chr 4:157,668,878...157,695,366
Ensembl chr 4:157,668,878...157,695,191 		JBrowse link
G Cd44 CD44 molecule involved_in ISO
IBA
IEA		 (PMID:17045821)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:17045821 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd74 CD74 molecule involved_in ISO
IBA
IEA
ISS		 (PMID:12782713), (PMID:17045821), (PMID:24942581)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
BHF-UCL		 PMID:12782713 PMID:17045821 PMID:24942581 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator IMP RGD PMID:23412386 RGD:11341713 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Chi3l1 chitinase 3 like 1 involved_in ISO
IEA
ISS		 (PMID:21385870)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21385870 GO_REF:0000024 GO_REF:0000107 NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit involved_in IMP
ISO
IEA
IDA		 PMID:11404397
UniProtKB:P05067 (PMID:11404397), (PMID:17898229), (PMID:20164328)
GO_REF:0000107		 RGD
Ensembl		 PMID:11404397 PMID:17898229 PMID:20164328 PMID:11404397 PMID:17898229 GO_REF:0000107, RGD:12790656, RGD:12050111 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Cib1 calcium and integrin binding 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:17975111)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:17975111 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:134,178,331...134,183,895
Ensembl chr 1:134,178,331...134,213,423 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:23959425)
MGI:1931805 (PMID:16399079)
GO_REF:0000033		 RGD
GO_Central		 PMID:16399079 PMID:23959425 GO_REF:0000033 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Csf1r colony stimulating factor 1 receptor involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:8007983)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:8007983 GO_REF:0000024 GO_REF:0000107 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:24520418) RGD PMID:24520418 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 acts_upstream_of_or_within ISO MGI:1341264 (PMID:22956548) RGD PMID:22956548 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl17 C-X-C motif chemokine ligand 17 involved_in ISO
ISS		 (PMID:23115081)
GO_REF:0000024		 RGD
UniProt		 PMID:23115081 GO_REF:0000024 NCBI chr 1:80,984,751...80,996,842
Ensembl chr 1:80,984,964...80,996,726 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 acts_upstream_of_or_within ISO (PMID:20376365) RGD PMID:20376365 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 IMP RGD PMID:21055410 RGD:5144006 NCBI chr15:48,189,476...48,228,750
Ensembl chr15:48,189,073...48,304,136 		JBrowse link
G Dcc DCC netrin 1 receptor IMP RGD PMID:15811950 RGD:2314384 NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 IMP RGD PMID:26674152 RGD:11554781 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ddt D-dopachrome tautomerase involved_in ISO UniProtKB:P14174 (PMID:21817065) RGD PMID:21817065 NCBI chr20:12,884,216...12,886,687
Ensembl chr20:12,884,243...12,888,482 		JBrowse link
G Dennd2b DENN domain containing 2B acts_upstream_of_or_within ISO (PMID:9632734) RGD PMID:9632734 NCBI chr 1:163,544,075...163,734,736
Ensembl chr 1:163,544,074...163,694,680 		JBrowse link
G Dnajc27 DnaJ heat shock protein family (Hsp40) member C27 involved_in ISO (PMID:24746703) RGD PMID:24746703 NCBI chr 6:27,068,713...27,098,449
Ensembl chr 6:27,068,686...27,098,449 		JBrowse link
G Drd2 dopamine receptor D2 IMP RGD PMID:18809670 RGD:2311559 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dstyk dual serine/threonine and tyrosine protein kinase involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(PMID:23862974)		 UniProt
GO_Central
Ensembl
RGD		 PMID:23862974 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr13:43,857,266...43,905,280
Ensembl chr13:43,857,266...43,905,269 		JBrowse link
G Dusp15 dual specificity phosphatase 15 involved_in IMP
IBA		 PMID:27891578
GO_REF:0000033		 GO_Central PMID:27891578 GO_REF:0000033, RGD:12903239 NCBI chr 3:141,408,495...141,419,137
Ensembl chr 3:141,408,498...141,418,999 		JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:16543720 RGD:4892323 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Egf epidermal growth factor IDA RGD PMID:17310240 RGD:1626216 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor involved_in ISO (PMID:20551055), (PMID:21673316) RGD PMID:20551055 PMID:21673316 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G ENSRNOG00000063241 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 Ensembl chr13:26,511,609...26,513,494 JBrowse link
G Epo erythropoietin IMP RGD PMID:21749867 RGD:10400910 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Epor erythropoietin receptor IMP RGD PMID:21749867 RGD:10400910 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 involved_in ISO
IEA
ISS		 (PMID:10348342)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:10348342 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Esr1 estrogen receptor 1 IDA RGD PMID:17928626 RGD:5128669 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 IDA
IMP		 RGD PMID:17928626 PMID:24440742 RGD:5128669, RGD:10045880 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:20215560)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:20215560 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO
IBA
ISS		 (PMID:10725339)
GO_REF:0000033
(PMID:20215560)
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:10725339 PMID:20215560 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 involved_in ISO (PMID:20208556) RGD PMID:20208556 NCBI chr 2:170,149,706...170,311,536
Ensembl chr 2:170,149,694...170,309,941 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 involved_in ISO (PMID:24226523) RGD PMID:24226523 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Ffar4 free fatty acid receptor 4 involved_in ISS
ISO		 GO_REF:0000024
(PMID:15774482)		 UniProt
RGD		 PMID:15774482 GO_REF:0000024 NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO (PMID:10903502), (PMID:19193866) RGD PMID:10903502 PMID:19193866 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:10903502), (PMID:19193866) RGD PMID:10903502 PMID:19193866 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgf1 fibroblast growth factor 1 involved_in ISO
ISS		 (PMID:18441324)
GO_REF:0000024		 RGD
UniProt		 PMID:18441324 GO_REF:0000024 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1345138|MGI:1345139|MGI:1859647|MGI:95523 (PMID:15130516), (PMID:17202188), (PMID:21764747) RGD PMID:15130516 PMID:17202188 PMID:21764747 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:11741978)		 Ensembl
RGD		 PMID:11741978 GO_REF:0000107 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818 		JBrowse link
G Fgf19 fibroblast growth factor 19 involved_in ISO (PMID:17623664), (PMID:19085950) RGD PMID:17623664 PMID:19085950 NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287 		JBrowse link
G Fgf2 fibroblast growth factor 2 involved_in
acts_upstream_of_or_within		 IDA
ISO		 (PMID:29501879)
(PMID:16858399)
(PMID:17167778)		 RGD PMID:16858399 PMID:17167778 PMID:29501879 PMID:19952283 RGD:2325174 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf20 fibroblast growth factor 20 acts_upstream_of_or_within IDA PMID:12704805 MGI PMID:12704805 RGD:8553960 NCBI chr16:52,030,549...52,038,201
Ensembl chr16:52,010,194...52,038,204 		JBrowse link
G Fgf21 fibroblast growth factor 21 involved_in ISO (PMID:17623664) RGD PMID:17623664 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgf23 fibroblast growth factor 23 involved_in ISO (PMID:17086194) RGD PMID:17086194 NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Fgf4 fibroblast growth factor 4 involved_in ISO (PMID:17167778) RGD PMID:17167778 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:99511 (PMID:24431450) RGD PMID:24431450 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Fgfbp3 fibroblast growth factor binding protein 3 involved_in ISO (PMID:20851768) RGD PMID:20851768 NCBI chr 1:234,644,023...234,646,028
Ensembl chr 1:234,644,019...234,646,547 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 acts_upstream_of_or_within ISO MGI:1099809 (PMID:17202188) RGD PMID:17202188 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 involved_in ISO (PMID:11294897) RGD PMID:11294897 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 involved_in ISO
IBA
IEA
ISS		 (PMID:21653700)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:21653700 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:10903502), (PMID:19193866) RGD PMID:10903502 PMID:19193866 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Flt4 Fms related receptor tyrosine kinase 4 involved_in ISO
IEA		 (PMID:11532940)
GO_REF:0000107		 RGD
Ensembl		 PMID:11532940 GO_REF:0000107 NCBI chr10:33,913,725...33,954,770
Ensembl chr10:33,913,608...33,954,770 		JBrowse link
G Fpr2 formyl peptide receptor 2 involved_in ISO UniProtKB:P05067-PRO_0000000092|UniProtKB:Q9UEW3 (PMID:20141570) RGD PMID:20141570 NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019 		JBrowse link
G Fshr follicle stimulating hormone receptor involved_in ISO
ISS		 (PMID:24058690)
GO_REF:0000024		 RGD
UniProt		 PMID:24058690 GO_REF:0000024 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Garem1 GRB2 associated regulator of MAPK1 subtype 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:19509291)
(PMID:36084556)		 RGD PMID:19509291 PMID:36084556 NCBI chr18:12,420,169...12,585,323
Ensembl chr18:12,423,882...12,585,345 		JBrowse link
G Gas6 growth arrest specific 6 acts_upstream_of_or_within ISO (PMID:15184064) RGD PMID:15184064 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gcg glucagon involved_in IEA
ISO		 GO_REF:0000107
(PMID:19915011)
(PMID:25050009)		 Ensembl
RGD		 PMID:19915011 PMID:25050009 GO_REF:0000107 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 involved_in ISO (PMID:21750175) RGD PMID:21750175 NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611 		JBrowse link
G Glipr2 GLI pathogenesis-related 2 involved_in ISO (PMID:23516513) RGD PMID:23516513 NCBI chr 5:58,170,417...58,202,258
Ensembl chr 5:58,170,425...58,202,272 		JBrowse link
G Gnai2 G protein subunit alpha i2 IMP RGD PMID:11495629 RGD:728462 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 IMP RGD PMID:28543567 RGD:14700993 NCBI chr 9:75,860,758...75,863,260
Ensembl chr 9:75,860,677...75,863,168 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA
ISO
IMP
IEA		 (PMID:21673097), (PMID:23545157)
GO_REF:0000107
PMID:23283935
(PMID:20551055), (PMID:21427217)
PMID:23907461		 RGD
Ensembl		 PMID:20551055 PMID:21427217 PMID:21673097 PMID:23545157 PMID:19717735 More... GO_REF:0000107, RGD:4892081, RGD:4892081, RGD:8553898, RGD:8553942, RGD:4892084 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gpnmb glycoprotein nmb involved_in ISO (PMID:18036345) RGD PMID:18036345 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21673108), (PMID:25297897)		 UniProt
RGD		 PMID:21673108 PMID:25297897 GO_REF:0000024 NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559 		JBrowse link
G Gpr55 G protein-coupled receptor 55 involved_in ISO (PMID:19805329) RGD PMID:19805329 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 IMP RGD PMID:23690069 RGD:13792722 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24161931)		 Ensembl
RGD		 PMID:24161931 GO_REF:0000107 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:18006747) RGD PMID:18006747 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Hcrtr1 hypocretin receptor 1 acts_upstream_of_or_within ISO (PMID:22028875) RGD PMID:22028875 NCBI chr 5:142,477,214...142,486,674
Ensembl chr 5:142,477,214...142,486,674 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:22370717)
(PMID:16365390)		 RGD PMID:16365390 PMID:22370717 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP RGD PMID:17161379 RGD:5508698 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in IMP
ISO		 (PMID:22065586) RGD PMID:22065586 PMID:18163378 RGD:2314843 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A involved_in ISO
IMP		 (PMID:19057895) RGD PMID:19057895 PMID:24997405 RGD:401938605 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B involved_in ISO
ISS
IEA		 (PMID:19057895)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19057895 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C involved_in ISO (PMID:19057895) RGD PMID:19057895 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Iapp islet amyloid polypeptide involved_in ISO ComplexPortal:CPX-3187|UniProtKB:O60896|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Icam1 intercellular adhesion molecule 1 involved_in ISO (PMID:10903502) RGD PMID:10903502 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19578119), (PMID:24508636)		 Ensembl
RGD		 PMID:19578119 PMID:24508636 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:16595703 RGD:2311095 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta involved_in IDA
ISO		 (PMID:19727662) RGD PMID:19727662 PMID:15671867 RGD:1358666 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 IDA RGD PMID:19061939 PMID:20227492 RGD:2306937, RGD:5128677 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhba inhibin subunit beta A IDA RGD PMID:27477354 RGD:151665478 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Ins2 insulin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:12059784)		 Ensembl
RGD		 PMID:12059784 GO_REF:0000107 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:17620283 RGD:4892659 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit acts_upstream_of_or_within ISO MGI:2673694 (PMID:25224220) RGD PMID:25224220 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kdr kinase insert domain receptor involved_in IEA
ISO		 GO_REF:0000107
(PMID:24863063)		 Ensembl
RGD		 PMID:24863063 GO_REF:0000107 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lgals9 galectin 9 involved_in ISO UniProtKB:Q99731 (PMID:24465902), (PMID:25754930) RGD PMID:24465902 PMID:25754930 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lrp1 LDL receptor related protein 1 IMP RGD PMID:24865476 RGD:13800516 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24375836)		 Ensembl
RGD		 PMID:24375836 GO_REF:0000107 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 involved_in ISO
IEA
ISS		 (PMID:28111074)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:28111074 GO_REF:0000024 GO_REF:0000107 NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:28111074)		 UniProt
Ensembl
RGD		 PMID:28111074 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:19664780) RGD PMID:19664780 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Marco macrophage receptor with collagenous structure involved_in IDA PMID:20141570 ARUK-UCL PMID:20141570 RGD:12907556 NCBI chr13:31,616,278...31,648,521
Ensembl chr13:31,616,278...31,648,521 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 involved_in ISO (PMID:23327923) RGD PMID:23327923 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO UniProtKB:P30046 (PMID:12782713), (PMID:17045821), (PMID:21817065)
(PMID:10364264), (PMID:17045821)		 RGD PMID:10364264 PMID:12782713 PMID:17045821 PMID:21817065 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:23239100) RGD PMID:23239100 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir23a microRNA 23a involved_in ISO RNAcentral:URS0000183BED_9606 (PMID:21536891) RGD PMID:21536891 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Mir27a microRNA 27a involved_in ISO RNAcentral:URS000059311D_9606 (PMID:21536891) RGD PMID:21536891 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b involved_in ISO RNAcentral:URS00003B95DA_9606 (PMID:21536891) RGD PMID:21536891 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mirlet7b microRNA let-7b involved_in ISO (PMID:26296645) RGD PMID:26296645 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270 		JBrowse link
G Mos MOS proto-oncogene, serine/threonine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:34779126)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:34779126 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:16,859,957...16,861,264
Ensembl chr 5:16,859,957...16,861,264 		JBrowse link
G Mt3 metallothionein 3 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:21726645)
GO_REF:0000033
(PMID:18295594)		 UniProt
RGD
GO_Central		 PMID:18295594 PMID:21726645 GO_REF:0000024 GO_REF:0000033 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mturn maturin, neural progenitor differentiation regulator homolog involved_in ISO
IEA		 (PMID:24681962)
GO_REF:0000107		 RGD
Ensembl		 PMID:24681962 GO_REF:0000107 NCBI chr 4:83,807,528...83,828,494
Ensembl chr 4:83,807,579...83,824,950 		JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:23354122 RGD:12798521 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
(PMID:19727662)		 Ensembl
RGD		 PMID:19727662 GO_REF:0000107 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Ndrg4 NDRG family member 4 involved_in IDA
IBA
IEA
ISO		 PMID:16408304
GO_REF:0000033
GO_REF:0000107
(PMID:12755708)		 GO_Central
Ensembl
RGD		 PMID:12755708 PMID:16408304 GO_REF:0000033 GO_REF:0000107, RGD:10047195 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914 		JBrowse link
G Necab2 N-terminal EF-hand calcium binding protein 2 involved_in ISO
IEA		 (PMID:19694902)
GO_REF:0000107		 RGD
Ensembl		 PMID:19694902 GO_REF:0000107 NCBI chr19:47,501,351...47,527,722
Ensembl chr19:47,501,302...47,527,684 		JBrowse link
G Nelfe negative elongation factor complex member E IMP RGD PMID:19014935 RGD:9693721 NCBI chr20:3,976,512...3,982,389
Ensembl chr20:3,976,518...3,982,355 		JBrowse link
G Ngf nerve growth factor IDA RGD PMID:17310240 PMID:25062286 RGD:1626216, RGD:401977578 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nod1 nucleotide-binding oligomerization domain containing 1 acts_upstream_of_or_within ISO (PMID:18261938) RGD PMID:18261938 NCBI chr 4:84,060,871...84,111,668
Ensembl chr 4:84,060,880...84,111,404 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within
involved_in		 ISO MGI:3529594 (PMID:18261938), (PMID:22033934)
(PMID:21156799)		 RGD PMID:18261938 PMID:21156799 PMID:22033934 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nodal nodal growth differentiation factor involved_in ISO (PMID:21116837) RGD PMID:21116837 NCBI chr20:29,368,436...29,376,837
Ensembl chr20:29,368,436...29,376,837 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:11306509) RGD PMID:11306509 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:11306509)		 Ensembl
RGD		 PMID:11306509 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Nox4 NADPH oxidase 4 involved_in IEA
ISO		 GO_REF:0000107
(PMID:17942966)		 Ensembl
RGD		 PMID:17942966 GO_REF:0000107 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Npnt nephronectin involved_in ISO (PMID:19944102) RGD PMID:19944102 NCBI chr 2:221,391,151...221,459,527
Ensembl chr 2:221,391,153...221,459,401 		JBrowse link
G Npsr1 neuropeptide S receptor 1 IMP RGD PMID:23761908 RGD:9831201 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558 		JBrowse link
G Nptn neuroplastin IDA RGD PMID:19952283 RGD:2325174 NCBI chr 8:58,996,873...59,063,402
Ensembl chr 8:58,996,887...59,063,401 		JBrowse link
G Npy neuropeptide Y IDA RGD PMID:21595512 RGD:10448272 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Npy5r neuropeptide Y receptor Y5 IMP RGD PMID:21595512 RGD:10448272 NCBI chr16:23,055,427...23,063,384
Ensembl chr16:23,055,427...23,063,382 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 IMP RGD PMID:23554738 RGD:11073697 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO
IEA
ISS		 (PMID:20682778)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20682778 GO_REF:0000024 GO_REF:0000107 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (PMID:23639442) RGD PMID:23639442 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISO (PMID:26078884) RGD PMID:26078884 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in
NOT|involved_in		 ISS
ISO		 GO_REF:0000024
(PMID:15488758)		 UniProt
RGD		 PMID:15488758 GO_REF:0000024 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Ntsr2 neurotensin receptor 2 IDA RGD PMID:16564027 RGD:9743898 NCBI chr 6:39,424,297...39,431,015
Ensembl chr 6:39,424,324...39,431,014 		JBrowse link
G Olr35 olfactory receptor 35 involved_in ISO (PMID:24999593) RGD PMID:24999593 NCBI chr 1:153,994,678...154,043,281
Ensembl chr 1:154,041,306...154,043,257 		JBrowse link
G Oprm1 opioid receptor, mu 1 involved_in IDA PMID:17384143 UniProt PMID:17384143 RGD:8656005 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in IDA PMID:20847060 BHF-UCL PMID:20847060 RGD:8554370 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457 		JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:28277742) RGD PMID:28277742 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808 		JBrowse link
G Pde8a phosphodiesterase 8A involved_in ISO
IBA		 (PMID:23509299)
GO_REF:0000033		 RGD
GO_Central		 PMID:23509299 GO_REF:0000033 NCBI chr 1:135,166,143...135,288,986
Ensembl chr 1:135,166,237...135,288,024 		JBrowse link
G Pde8b phosphodiesterase 8B involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209 		JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
IBA
IEA
ISS		 (PMID:11788434)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:11788434 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in IEA
IBA
ISS
ISO		 GO_REF:0000107
GO_REF:0000033
GO_REF:0000024
(PMID:11788434), (PMID:16530387), (PMID:17942966)		 Ensembl
GO_Central
UniProt
RGD		 PMID:11788434 PMID:16530387 PMID:17942966 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfc platelet derived growth factor C involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433 		JBrowse link
G Pdgfd platelet derived growth factor D involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISO
IEA
ISS		 (PMID:10734113)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:10734113 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta involved_in ISO
IEA
ISS		 (PMID:21679854)
(PMID:14624252), (PMID:17942966)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:14624252 PMID:17942966 PMID:21679854 GO_REF:0000024 GO_REF:0000107 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Phb1 prohibitin 1 involved_in ISO (PMID:22417827) RGD PMID:22417827 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Phb2 prohibitin 2 involved_in ISO
IEA		 (PMID:22417827)
GO_REF:0000107		 RGD
Ensembl		 PMID:22417827 GO_REF:0000107 NCBI chr 4:157,517,662...157,522,268
Ensembl chr 4:157,517,577...157,522,272 		JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in ISO (PMID:22837859) RGD PMID:22837859 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in ISO
IEA		 (PMID:22837859)
GO_REF:0000107		 RGD
Ensembl		 PMID:22837859 GO_REF:0000107 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Prkca protein kinase C, alpha involved_in IMP PMID:11864993 UniProt PMID:11864993 RGD:8554603 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prkcz protein kinase C, zeta involved_in IMP
ISS
ISO		 PMID:8557035
GO_REF:0000024
(PMID:11035106)		 UniProt
RGD		 PMID:11035106 PMID:8557035 GO_REF:0000024, RGD:8554313 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Prkd2 protein kinase D2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:17226786)		 UniProt
RGD		 PMID:17226786 GO_REF:0000024 NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376 		JBrowse link
G Prxl2c peroxiredoxin like 2C involved_in ISO (PMID:29901208) RGD PMID:29901208 NCBI chr17:812,199...839,536
Ensembl chr17:812,213...844,075 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO (PMID:25512490) RGD PMID:25512490 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in ISO
ISS		 (PMID:7544443)
GO_REF:0000024		 RGD
UniProt		 PMID:7544443 GO_REF:0000024 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in
acts_upstream_of_or_within		 ISS
ISO
IBA
IEA		 GO_REF:0000024
MGI:87860|MGI:99604 (PMID:18827006), (PMID:24431450)
GO_REF:0000033
GO_REF:0000107
(PMID:28074573)		 UniProt
RGD
GO_Central
Ensembl		 PMID:18827006 PMID:24431450 PMID:28074573 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO (PMID:23991106) RGD PMID:23991106 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO UniProtKB:P05480 (PMID:15661907) RGD PMID:15661907 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Pycard PYD and CARD domain containing involved_in ISO (PMID:21487011) RGD PMID:21487011 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Ramp3 receptor activity modifying protein 3 involved_in ISO ComplexPortal:CPX-1134|UniProtKB:P30988 (PMID:22500019) RGD PMID:22500019 NCBI chr14:81,527,404...81,544,905
Ensembl chr14:81,527,385...81,544,902 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in
acts_upstream_of_or_within		 IMP
ISO		 PMID:17724123
MGI:894315 (PMID:23616533)		 RGD PMID:23616533 PMID:17724123 RGD:8554481 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family acts_upstream_of_or_within ISO MGI:97852 (PMID:23616533) RGD PMID:23616533 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 IMP RGD PMID:16507992 RGD:11534985 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in IMP
ISO
ISS		 PMID:17724123
(PMID:16272156), (PMID:23800469)
GO_REF:0000024		 RGD
UniProt		 PMID:16272156 PMID:23800469 PMID:17724123 GO_REF:0000024, RGD:8554481 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (PMID:11894098), (PMID:18261938) RGD PMID:11894098 PMID:18261938 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:24942581) RGD PMID:24942581 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein involved_in ISO (PMID:21930792) RGD PMID:21930792 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171 		JBrowse link
G Sema7a semaphorin 7A (John Milton Hagen blood group) involved_in ISO (PMID:12879062)
(PMID:17377534)		 RGD PMID:12879062 PMID:17377534 NCBI chr 8:58,348,448...58,370,536
Ensembl chr 8:58,348,448...58,370,536 		JBrowse link
G Serpinf2 serpin family F member 2 involved_in ISO (PMID:20008146) RGD PMID:20008146 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243 		JBrowse link
G Shc1 SHC adaptor protein 1 involved_in ISO
IEA		 (PMID:20624904)
GO_REF:0000107		 RGD
Ensembl		 PMID:20624904 GO_REF:0000107 NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (PMID:20231852) RGD PMID:20231852 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Slc30a10 solute carrier family 30, member 10 acts_upstream_of ISO (PMID:26728129) RGD PMID:26728129 NCBI chr13:96,998,143...97,048,076
Ensembl chr13:96,998,143...97,009,103 		JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 involved_in ISO (PMID:18070883) RGD PMID:18070883 NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP
ISO		 PMID:16530387
(PMID:17045821)		 RGD PMID:17045821 PMID:16530387 RGD:8553998 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Sstr4 somatostatin receptor 4 IDA RGD PMID:8175684 RGD:2325010 NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689 		JBrowse link
G Tek TEK receptor tyrosine kinase involved_in
acts_upstream_of_or_within_positive_effect		 ISO (PMID:19615361)
(PMID:18425120)		 RGD PMID:18425120 PMID:19615361 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tff2 trefoil factor 2 acts_upstream_of_or_within ISO UniProtKB:P61072 (PMID:19064997) RGD PMID:19064997 NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
ISS		 (PMID:25310401)
GO_REF:0000024		 RGD
UniProt		 PMID:25310401 GO_REF:0000024 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Thpo thrombopoietin involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:22128142)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:22128142 GO_REF:0000024 GO_REF:0000033 Ensembl chr11:80,182,820...80,188,167 JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:11544529) RGD PMID:11544529 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlr2 toll-like receptor 2 acts_upstream_of_or_within ISO MGI:2674036 (PMID:22033934) RGD PMID:22033934 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:18261938)		 Ensembl
RGD		 PMID:18261938 GO_REF:0000107 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnfaip8l3 TNF alpha induced protein 8 like 3 involved_in ISO (PMID:25242044) RGD PMID:25242044 NCBI chr 8:54,413,503...54,455,512
Ensembl chr 8:54,414,457...54,500,079 		JBrowse link
G Tnfrsf11a TNF receptor superfamily member 11A involved_in ISO (PMID:18606301) RGD PMID:18606301 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18606301)		 Ensembl
RGD		 PMID:18606301 GO_REF:0000107 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tpbg trophoblast glycoprotein acts_upstream_of_or_within ISO MGI:103556|MGI:109563 (PMID:20376365), (PMID:22956548) RGD PMID:20376365 PMID:22956548 NCBI chr 8:86,793,953...86,797,324
Ensembl chr 8:86,793,749...86,797,741 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO
IBA		 (PMID:11602640), (PMID:27995897)
(PMID:28592261)
GO_REF:0000033		 RGD
GO_Central		 PMID:11602640 PMID:27995897 PMID:28592261 GO_REF:0000033 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (PMID:23021218) RGD PMID:23021218 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:23639442), (PMID:24863063)
(PMID:21828096)		 RGD PMID:21828096 PMID:23639442 PMID:24863063 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfb vascular endothelial growth factor B involved_in ISO (PMID:18259607) RGD PMID:18259607 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    cellular process 19525
      signal transduction 7251
        intracellular signal transduction 3150
          positive regulation of intracellular signal transduction 1242
            positive regulation of MAPK cascade 549
              positive regulation of ERK1 and ERK2 cascade 227
Path 2
Term Annotations click to browse term
  biological_process 20536
    biological regulation 13822
      regulation of biological process 13376
        signaling 7809
          signal transduction 7251
            intracellular signal transduction 3150
              intracellular signaling cassette 2022
                MAPK cascade 870
                  regulation of MAPK cascade 773
                    regulation of ERK1 and ERK2 cascade 338
                      positive regulation of ERK1 and ERK2 cascade 227
paths to the root