ONTOLOGY REPORT - ANNOTATIONS
Term: chaperone-mediated autophagy
Accession: GO:0061684
browse the term
Definition: The autophagy process which begins when chaperones and co-chaperones recognize a target motif and unfold the substrate protein. The proteins are then transported to the lysosome where they are degraded.
Synonyms: exact_synonym: CASA; chaperone-assisted selective autophagy
related_synonym: CMA
xref: Reactome:R-HSA-9613829 "Chaperone Mediated Autophagy"; Wikipedia:Chaperone-mediated_autophagy
G
Atg5
autophagy related 5
involved_in
IMP
PMID:23434281
ARUK-UCL
PMID:23434281
RGD:12793031
NCBI chr20:49,380,835...49,471,826
Ensembl chr20:47,798,290...47,889,209
G
Atg7
autophagy related 7
involved_in
IMP
PMID:23434281
ARUK-UCL
PMID:23434281
RGD:12793031
NCBI chr 4:149,390,000...149,597,534
Ensembl chr 4:147,718,752...147,925,593
G
Hsp90aa1
heat shock protein 90 alpha family class A member 1
involved_in
NAS
PMID:18644871
ParkinsonsUK-UCL
PMID:18644871
RGD:10412301
NCBI chr 6:135,523,604...135,529,687
Ensembl chr 6:129,702,383...129,707,268
G
Hsp90ab1
heat shock protein 90 alpha family class B member 1
involved_in
NAS
PMID:18644871
ParkinsonsUK-UCL
PMID:18644871
RGD:10412301
NCBI chr 9:22,930,249...22,935,929
Ensembl chr 9:15,433,691...15,438,488
G
Hspa8
heat shock protein family A (Hsp70) member 8
involved_in acts_upstream_of_or_within
IDA IGI
PMID:18644871
ParkinsonsUK-UCL MGI
PMID:18644871 PMID:18644871
RGD:10412301 , RGD:10412301
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:41,183,264...41,187,259
G
Lamp2
lysosomal-associated membrane protein 2
involved_in acts_upstream_of_or_within
IDA ISO
PMID:11082038 UniProtKB:P13473 (PMID:18644871), (PMID:27628032) (PMID:18579532) (PMID:36586411) (PMID:24880125), (PMID:27628032) (PMID:8662539)
RGD
PMID:8662539 PMID:18579532 PMID:18644871 PMID:24880125 PMID:27628032 PMID:36586411 PMID:11082038 More...
RGD:1581607
NCBI chr X:122,038,734...122,087,745
Ensembl chr X:117,057,606...117,260,522
G
Synpo2
synaptopodin 2
involved_in
IMP
PMID:23434281
ARUK-UCL
PMID:23434281
RGD:12793031
NCBI chr 2:211,217,099...211,371,267
Ensembl chr 2:211,216,783...211,371,267
G
Ctsa
cathepsin A
involved_in
ISO
UniProtKB:P10619 (PMID:12505983)
RGD
PMID:12505983
NCBI chr 3:173,988,443...173,994,320
Ensembl chr 3:153,568,381...153,576,215
G
Snca
synuclein alpha
involved_in
ISO IEA
(PMID:20697033) GO_REF:0000107
RGD Ensembl
PMID:20697033
GO_REF:0000107
NCBI chr 4:91,026,474...91,127,444
Ensembl chr 4:89,696,420...89,796,262
G
Plk3
polo-like kinase 3
involved_in
ISO
(PMID:27344333)
RGD
PMID:27344333
NCBI chr 5:135,843,725...135,848,900
Ensembl chr 5:130,607,142...130,612,317
G
Clu
clusterin
involved_in
ISO IEA
(PMID:9228033) GO_REF:0000107
RGD Ensembl
PMID:9228033
GO_REF:0000107
NCBI chr15:44,336,619...44,375,861
Ensembl chr15:40,174,617...40,200,315
G
Hspa8
heat shock protein family A (Hsp70) member 8
involved_in
ISS ISO
GO_REF:0000024 (PMID:11559757), (PMID:26212789), (PMID:36586411)
UniProt RGD
PMID:11559757 PMID:26212789 PMID:36586411
GO_REF:0000024
NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:41,183,264...41,187,259
G
Lamp2
lysosomal-associated membrane protein 2
involved_in acts_upstream_of_or_within
ISO IBA IEA IGI IMP ISS
(PMID:27628032) GO_REF:0000033 GO_REF:0000107 PMID:18644871 GO_REF:0000024
RGD GO_Central Ensembl UniProt
PMID:27628032 PMID:18644871 PMID:18644871
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107, RGD:10412301 , RGD:10412301
NCBI chr X:122,038,734...122,087,745
Ensembl chr X:117,057,606...117,260,522
G
Gfap
glial fibrillary acidic protein
involved_in
ISO IMP IBA
(PMID:20797626) GO_REF:0000033
RGD GO_Central
PMID:20797626 PMID:20797626
GO_REF:0000033, RGD:10412296
NCBI chr10:88,352,987...88,361,661
Ensembl chr10:87,852,890...87,861,589
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all