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ONTOLOGY REPORT - ANNOTATIONS

Term:cardiac neural crest cell differentiation involved in heart development
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Accession:GO:0061307 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.


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cardiac neural crest cell differentiation involved in heart development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd11 ankyrin repeat domain containing 11 acts_upstream_of_or_within ISO (PMID:38951500) RGD PMID:38951500 NCBI chr19:67,848,836...68,007,491
Ensembl chr19:50,940,299...51,098,962 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (PMID:19705442) RGD PMID:19705442 NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
cardiac neural crest cell development involved in heart development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 acts_upstream_of_or_within ISO MGI:2179740 (PMID:11694877) RGD PMID:11694877 NCBI chr 1:14,132,303...14,134,746
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within ISO
IEA		 MGI:1346859 (PMID:18952847)
GO_REF:0000107		 RGD
Ensembl		 PMID:18952847 GO_REF:0000107 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 acts_upstream_of_or_within ISO MGI:1346858 (PMID:18952847) RGD PMID:18952847 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
cardiac neural crest cell development involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589208 (PMID:21098571) RGD PMID:21098571 NCBI chr 6:129,392,298...129,457,252
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO
IEA		 (PMID:19008477)
GO_REF:0000107		 RGD
Ensembl		 PMID:19008477 GO_REF:0000107 NCBI chr16:37,928,145...37,931,488
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO
IEA		 (PMID:19609448)
GO_REF:0000107		 RGD
Ensembl		 PMID:19609448 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19509466)		 Ensembl
RGD		 PMID:19509466 GO_REF:0000107 NCBI chr 3:144,859,453...144,894,883
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857265 (PMID:18539270) RGD PMID:18539270 NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc42 cell division cycle 42 involved_in ISO (PMID:31219639) RGD PMID:31219639 NCBI chr 5:154,838,478...154,876,629
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Edn1 endothelin 1 involved_in ISO
IEA		 (PMID:31219639)
GO_REF:0000107		 RGD
Ensembl		 PMID:31219639 GO_REF:0000107 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A involved_in IEA
ISO		 GO_REF:0000107
MGI:1857473|MGI:2687362 (PMID:31219639)		 Ensembl
RGD		 PMID:31219639 GO_REF:0000107 NCBI chr19:47,137,360...47,207,961
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Folr1 folate receptor alpha involved_in ISO
IEA		 (PMID:17286298)
GO_REF:0000107		 RGD
Ensembl		 PMID:17286298 GO_REF:0000107 NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 acts_upstream_of_or_within ISO
IEA		 MGI:2386570|MGI:3803647 (PMID:20144608)
GO_REF:0000107		 RGD
Ensembl		 PMID:20144608 GO_REF:0000107 NCBI chr16:37,928,145...37,931,488
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Nrp1 neuropilin 1 NOT|involved_in ISO (PMID:26053665) RGD PMID:26053665 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Pitx2 paired-like homeodomain 2 involved_in ISO (PMID:12464179) RGD PMID:12464179 NCBI chr 2:220,391,417...220,411,588
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:1857265 (PMID:18539270) RGD PMID:18539270 NCBI chr 6:56,402,309...56,404,303
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
neural crest cell migration involved in heart formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Folr1 folate receptor alpha involved_in ISO
IEA		 (PMID:17286298)
GO_REF:0000107		 RGD
Ensembl		 PMID:17286298 GO_REF:0000107 NCBI chr 1:165,631,462...165,650,430
Ensembl chr 1:156,219,460...156,230,667 		JBrowse link
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:P23359 (PMID:23863481)		 Ensembl
RGD		 PMID:23863481 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp7 bone morphogenetic protein 7 involved_in ISO
IEA		 UniProtKB:P21275 (PMID:23863481)
GO_REF:0000107		 RGD
Ensembl		 PMID:23863481 GO_REF:0000107 NCBI chr 3:182,059,318...182,135,273
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Sema3c semaphorin 3C involved_in ISO
IEA		 (PMID:26053665)
GO_REF:0000107		 RGD
Ensembl		 PMID:26053665 GO_REF:0000107 NCBI chr 4:18,538,452...18,702,453
Ensembl chr 4:17,583,212...17,746,534 		JBrowse link
regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eng endoglin NOT|involved_in ISO (PMID:17628518) RGD PMID:17628518 NCBI chr 3:36,332,190...36,370,324
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      cellular developmental process 4838
        cell differentiation 4837
          cardiocyte differentiation 211
            cardiac neural crest cell differentiation involved in heart development 20
              cardiac neural crest cell development involved in heart development + 18
Path 2
Term Annotations click to browse term
  biological_process 20567
    developmental process 7160
      anatomical structure development 6656
        multicellular organism development 5362
          system development 4644
            circulatory system development 1387
              heart development 750
                cardiocyte differentiation 211
                  cardiac neural crest cell differentiation involved in heart development 20
                    cardiac neural crest cell development involved in heart development + 18
paths to the root