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ONTOLOGY REPORT - ANNOTATIONS


Term:3'-UTR-mediated mRNA destabilization
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Accession:GO:0061158 term browser browse the term
Definition:An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.


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3'-UTR-mediated mRNA destabilization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 involved_in ISO (PMID:21336257) UniProt PMID:21336257 NCBI chrNW_004624737:3,352,064...3,570,317
Ensembl chrNW_004624737:3,355,360...3,542,731
JBrowse link
G Dhx36 DEAH-box helicase 36 involved_in ISO (PMID:26489465) UniProt PMID:26489465 NCBI chrNW_004624730:31,857,157...31,913,985
Ensembl chrNW_004624730:31,855,992...31,914,253
JBrowse link
G Dnd1 DND microRNA-mediated repression inhibitor 1 involved_in ISO (PMID:28297718) CACAO PMID:28297718 NCBI chrNW_004624743:33,421,810...33,424,515
Ensembl chrNW_004624743:33,421,810...33,424,635
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D ISO RGD PMID:20805360 RGD:10042974 NCBI chrNW_004624757:8,532,373...8,549,840
Ensembl chrNW_004624757:8,531,601...8,549,835
JBrowse link
G Khsrp KH-type splicing regulatory protein involved_in ISO (PMID:28275056)
(PMID:16126846)
CACAO
UniProt
PMID:16126846 PMID:28275056 NCBI chrNW_004624828:3,535,372...3,546,083
Ensembl chrNW_004624828:3,535,093...3,545,978
JBrowse link
G Mov10 Mov10 RNA helicase involved_in ISO (PMID:24726324) UniProt PMID:24726324 NCBI chrNW_004624772:8,458,470...8,481,462
Ensembl chrNW_004624772:8,459,517...8,484,972
JBrowse link
G Plekhn1 pleckstrin homology domain containing N1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624818:8,537,044...8,545,393
Ensembl chrNW_004624818:8,537,631...8,544,676
JBrowse link
G Rbm24 RNA binding motif protein 24 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624756:9,253,310...9,262,859
Ensembl chrNW_004624756:9,250,945...9,262,899
JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO (PMID:26000482) UniProt PMID:26000482 NCBI chrNW_004624771:7,837,547...7,948,217 JBrowse link
G Tardbp TAR DNA binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624818:1,759,496...1,789,806
Ensembl chrNW_004624818:1,759,497...1,789,813
JBrowse link
G Trim71 tripartite motif containing 71 involved_in ISO (PMID:23125361) CACAO PMID:23125361 NCBI chrNW_004624788:10,858,490...10,929,693
Ensembl chrNW_004624788:10,859,932...10,929,029
JBrowse link
G Upf1 UPF1 RNA helicase and ATPase involved_in ISO (PMID:24726324) UniProt PMID:24726324 NCBI chrNW_004624908:1,909,995...1,935,370
Ensembl chrNW_004624908:1,910,315...1,933,655
JBrowse link
G Zc3h12a zinc finger CCCH-type containing 12A involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624764:20,224,919...20,234,108
Ensembl chrNW_004624764:20,224,906...20,234,629
JBrowse link
G Zc3h12d zinc finger CCCH-type containing 12D involved_in ISO (PMID:26134560) UniProt PMID:26134560 NCBI chrNW_004624785:8,588,480...8,613,199 JBrowse link
G Zfp36 ZFP36 ring finger protein involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004624794:12,732,222...12,738,006
Ensembl chrNW_004624794:12,734,191...12,737,971
JBrowse link
G Zfp36l1 ZFP36 ring finger protein like 1 involved_in IEA UniProt
Ensembl
GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004624734:32,251,100...32,256,458
Ensembl chrNW_004624734:32,251,114...32,257,211
JBrowse link
G Zfp36l2 ZFP36 ring finger protein like 2 involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004624738:24,743,388...24,747,572
Ensembl chrNW_004624738:24,744,213...24,747,591
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17638
    biological regulation 11844
      regulation of biological quality 3007
        regulation of RNA stability 181
          regulation of mRNA stability 168
            mRNA destabilization 95
              3'-UTR-mediated mRNA destabilization 17
Path 2
Term Annotations click to browse term
  biological_process 17638
    biological regulation 11844
      regulation of biological process 11485
        regulation of cellular process 11159
          regulation of metabolic process 5974
            regulation of biosynthetic process 4840
              regulation of macromolecule biosynthetic process 4648
                regulation of gene expression 4537
                  negative regulation of gene expression 1077
                    mRNA catabolic process 249
                      regulation of mRNA catabolic process 183
                        regulation of mRNA stability 168
                          mRNA destabilization 95
                            3'-UTR-mediated mRNA destabilization 17
paths to the root