Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:multicellular organismal-level iron ion homeostasis
go back to main search page
Accession:GO:0060586 term browser browse the term
Definition:A chemical homeostatic process involved in the maintenance of a steady state level of iron within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell.
Synonyms:exact_synonym: multicellular organismal iron ion homeostasis


show annotations for term's descendants           Sort by:
multicellular organismal-level iron ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank1 ankyrin 1 acts_upstream_of_or_within ISO MGI:5502651 (PMID:23390527) RGD PMID:23390527 NCBI chr16:75,578,824...75,757,464
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G B2m beta-2 microglobulin acts_upstream_of_or_within ISO (PMID:11113132) RGD PMID:11113132 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Bmp6 bone morphogenetic protein 6 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:26582087), (PMID:28335084), (PMID:32464486)
(PMID:19252488)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19252488 PMID:26582087 PMID:28335084 PMID:32464486 GO_REF:0000024 GO_REF:0000107 NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Btbd9 BTB domain containing 9 acts_upstream_of_or_within ISO
IEA		 MGI:4127237 (PMID:22678064)
GO_REF:0000107		 RGD
Ensembl		 PMID:22678064 GO_REF:0000107 NCBI chr20:8,287,813...8,645,437
Ensembl chr20:8,288,711...8,643,960 		JBrowse link
G Cybrd1 cytochrome b reductase 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:30272000)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:30272000 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:55,934,874...55,962,132
Ensembl chr 3:55,934,874...55,962,108 		JBrowse link
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 acts_upstream_of_or_within ISO
IEA		 MGI:2679454 (PMID:17932563)
GO_REF:0000107		 RGD
Ensembl		 PMID:17932563 GO_REF:0000107 NCBI chr12:15,824,431...15,858,266
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Epas1 endothelial PAS domain protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:109169 (PMID:22128145)
GO_REF:0000107		 RGD
Ensembl		 PMID:22128145 GO_REF:0000107 NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
G Epb42 erythrocyte membrane protein band 4.2 acts_upstream_of_or_within ISO
IEA		 MGI:2182816 (PMID:10359562)
GO_REF:0000107		 RGD
Ensembl		 PMID:10359562 GO_REF:0000107 NCBI chr 3:128,433,460...128,451,683
Ensembl chr 3:107,979,713...107,997,932 		JBrowse link
G Fbxl5 F-box and leucine-rich repeat protein 5 acts_upstream_of_or_within ISO MGI:1928268|MGI:5295288 (PMID:21907140) RGD PMID:21907140 NCBI chr14:71,517,452...71,559,850
Ensembl chr14:67,267,801...67,347,383 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO
IEA		 MGI:1858114 (PMID:17003376)
GO_REF:0000107		 RGD
Ensembl		 PMID:17003376 GO_REF:0000107 NCBI chr18:60,215,325...60,248,525
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hamp hepcidin antimicrobial peptide involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:12469120)
GO_REF:0000107
MGI:3701082|MGI:4351741 (PMID:16574947), (PMID:20113314), (PMID:20530874), (PMID:20811044), (PMID:22128145), (PMID:23637785), (PMID:24357728), (PMID:24561287), (PMID:24646470)		 RGD
Ensembl		 PMID:12469120 PMID:16574947 PMID:20113314 PMID:20530874 PMID:20811044 More... GO_REF:0000107 NCBI chr 1:95,298,332...95,300,271
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Heph hephaestin involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:9988272)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9988272 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:65,160,628...65,412,457
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Hfe homeostatic iron regulator involved_in
acts_upstream_of_or_within		 IEP
ISO		 (PMID:21173098)
MGI:1934013|MGI:2181388|MGI:2385353|MGI:3775648 (PMID:10077651), (PMID:15131800), (PMID:15914561), (PMID:21059897), (PMID:22960056)		 RGD PMID:10077651 PMID:15131800 PMID:15914561 PMID:21059897 PMID:21173098 More... RGD:1582699 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hjv hemojuvelin BMP co-receptor acts_upstream_of_or_within ISO
IEA		 UniProtKB:Q92859 (PMID:16075058)
MGI:3587746|MGI:3587747 (PMID:16075058), (PMID:19751239), (PMID:22960056), (PMID:24409331)
GO_REF:0000107		 RGD
Ensembl		 PMID:16075058 PMID:19751239 PMID:22960056 PMID:24409331 GO_REF:0000107 NCBI chr 2:186,754,801...186,758,708
Ensembl chr 2:184,065,970...184,069,850 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in ISO
IEA		 (PMID:9884342)
GO_REF:0000107		 RGD
Ensembl		 PMID:9884342 GO_REF:0000107 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:1857180 (PMID:11092755) RGD PMID:11092755 NCBI chr14:80,070,456...80,219,668
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Hyal2 hyaluronidase 2 acts_upstream_of_or_within ISO
IEA		 MGI:3836764 (PMID:18772348)
GO_REF:0000107		 RGD
Ensembl		 PMID:18772348 GO_REF:0000107 NCBI chr 8:117,121,802...117,125,494
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Ireb2 iron responsive element binding protein 2 acts_upstream_of_or_within ISO
IEA		 MGI:2152883 (PMID:21907140)
GO_REF:0000107		 RGD
Ensembl		 PMID:21907140 GO_REF:0000107 NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Mir122 microRNA 122 acts_upstream_of_or_within ISO MGI:2676805 (PMID:21364282) RGD PMID:21364282 NCBI chr18:61,028,817...61,028,901 JBrowse link
G Mir17 microRNA 17 acts_upstream_of_or_within ISO (PMID:21364282) RGD PMID:21364282 NCBI chr15:98,587,848...98,587,931
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO
IEA		 MGI:1934018 (PMID:29624734)
GO_REF:0000107		 RGD
Ensembl		 PMID:29624734 GO_REF:0000107 NCBI chr10:86,501,864...86,509,333
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Neo1 neogenin 1 acts_upstream_of_or_within ISO
IEA		 UniProtKB:Q6ZVN8 (PMID:16075058)
GO_REF:0000107		 RGD
Ensembl		 PMID:16075058 GO_REF:0000107 NCBI chr 8:68,169,711...68,322,158
Ensembl chr 8:59,275,569...59,430,348 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:22952941)		 Ensembl
Alzheimers_University_of_Toronto
RGD		 PMID:22952941 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:153,468,982...153,550,086
Ensembl chr 1:144,056,721...144,137,557 		JBrowse link
G Rhag Rh-associated glycoprotein acts_upstream_of_or_within ISO
IEA		 MGI:5318589 (PMID:19807729)
GO_REF:0000107		 RGD
Ensembl		 PMID:19807729 GO_REF:0000107 NCBI chr 9:27,566,349...27,594,390
Ensembl chr 9:20,069,807...20,097,836 		JBrowse link
G Rhd Rh blood group, D antigen acts_upstream_of_or_within ISO MGI:5318588 (PMID:19807729) RGD PMID:19807729 NCBI chr 5:152,371,160...152,405,396
Ensembl chr 5:147,087,518...147,121,715 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857755|MGI:2446573 (PMID:19321419), (PMID:9824471)
GO_REF:0000107		 RGD
Ensembl		 PMID:9824471 PMID:19321419 GO_REF:0000107 NCBI chr 9:83,406,327...83,417,252
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Slc11a2 solute carrier family 11 member 2 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:15459009)
GO_REF:0000107
MGI:1856400 (PMID:18076961), (PMID:5070129)		 RGD
Ensembl		 PMID:5070129 PMID:15459009 PMID:18076961 GO_REF:0000107 NCBI chr 7:133,381,878...133,429,921
Ensembl chr 7:131,503,081...131,540,145 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1889622 (PMID:15342464), (PMID:19596281)
(PMID:15084469)
GO_REF:0000107		 RGD
Ensembl		 PMID:15084469 PMID:15342464 PMID:19596281 GO_REF:0000107 NCBI chr 9:55,525,457...55,633,463
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO
IEA		 MGI:1857344 (PMID:15205258)
GO_REF:0000107		 RGD
Ensembl		 PMID:15205258 GO_REF:0000107 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tf transferrin involved_in ISO (PMID:11113131) RGD PMID:11113131 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tfr2 transferrin receptor 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:21173098)
MGI:2384726 (PMID:22960056)		 RGD PMID:21173098 PMID:22960056 NCBI chr12:24,744,450...24,761,413
Ensembl chr12:19,107,673...19,124,591 		JBrowse link
G Tfrc transferrin receptor involved_in ISO
IEA		 (PMID:26642240)
GO_REF:0000107		 RGD
Ensembl		 PMID:26642240 GO_REF:0000107 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tmprss6 transmembrane serine protease 6 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:18408718)
MGI:3776631 (PMID:19751239)
GO_REF:0000107		 RGD
Ensembl		 PMID:18408718 PMID:19751239 GO_REF:0000107 NCBI chr 7:111,871,504...111,902,127
Ensembl chr 7:109,985,931...110,021,624 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    multicellular organismal process 9031
      multicellular organismal-level homeostasis 979
        multicellular organismal-level chemical homeostasis 88
          multicellular organismal-level iron ion homeostasis 33
Path 2
Term Annotations click to browse term
  biological_process 20567
    homeostatic process 2032
      chemical homeostasis 1241
        monoatomic ion homeostasis 687
          monoatomic cation homeostasis 673
            multicellular organismal-level iron ion homeostasis 33
paths to the root