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ONTOLOGY REPORT - ANNOTATIONS


Term:membrane hyperpolarization
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Accession:GO:0060081 term browser browse the term
Definition:The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.


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membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:17001300 RGD:6903222 NCBI chrNW_004936627:1,555,151...1,584,370
Ensembl chrNW_004936627:1,554,873...1,584,638
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936492:4,125,182...4,232,239
Ensembl chrNW_004936492:4,125,173...4,236,062
JBrowse link
G Cftr CF transmembrane conductance regulator involved_in ISO (PMID:21976599) UniProt PMID:21976599 NCBI chrNW_004936589:1,565,933...1,719,208 JBrowse link
G Cntf ciliary neurotrophic factor ISO in fast-twitch flexor digitorum brevis muscle fibers RGD PMID:15831538 RGD:1626125 NCBI chrNW_004936581:3,710,171...3,715,753
Ensembl chrNW_004936581:3,710,160...3,715,638
JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936568:3,508,212...3,694,459
Ensembl chrNW_004936568:3,511,244...3,694,781
JBrowse link
G Kcnj10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:17091490 RGD:2326042 NCBI chrNW_004936740:555,948...589,219
Ensembl chrNW_004936740:555,998...586,353
JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO MGI MGI:62459 NCBI chrNW_004936514:10,735,247...10,787,682
Ensembl chrNW_004936514:10,735,809...10,787,678
JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936470:16,712,508...17,009,648
Ensembl chrNW_004936470:16,712,703...17,009,397
JBrowse link
G LOC101954543 caspase-1-like acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936551:3,230,060...3,240,496 JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936623:2,422,780...2,436,817
Ensembl chrNW_004936623:2,422,833...2,436,817
JBrowse link
G Prkcz protein kinase C zeta ISO RGD PMID:15062979 RGD:1642685 NCBI chrNW_004936737:1,303,502...1,383,135
Ensembl chrNW_004936737:1,303,887...1,321,944
JBrowse link
G Slc26a3 solute carrier family 26 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:16,350,746...16,374,911
Ensembl chrNW_004936479:16,350,773...16,377,367
JBrowse link
negative regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crtc1 CREB regulated transcription coactivator 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chrNW_004936596:2,551,621...2,625,327
Ensembl chrNW_004936596:2,551,506...2,625,327
JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 ISO RGD PMID:28993448 RGD:329848961 NCBI chrNW_004936492:4,624,013...4,826,715
Ensembl chrNW_004936492:4,645,167...4,821,291
JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chrNW_004936489:11,178,338...11,191,601
Ensembl chrNW_004936489:11,178,015...11,191,781
JBrowse link
positive regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:15803439), (PMID:17703433) BHF-UCL PMID:15803439 PMID:17703433 NCBI chrNW_004936484:19,713,299...19,721,144
Ensembl chrNW_004936484:19,716,165...19,721,261
JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:30408474 RGD:26923909 NCBI chrNW_004936480:17,051,902...17,416,335
Ensembl chrNW_004936480:17,051,898...17,413,657
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chrNW_004936521:2,000,113...2,706,010
Ensembl chrNW_004936521:2,000,109...2,705,365
JBrowse link
G Trpc1 transient receptor potential cation channel subfamily C member 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chrNW_004936540:4,340,672...4,417,655
Ensembl chrNW_004936540:4,323,528...4,418,685
JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chrNW_004936769:1,424,526...1,447,547
Ensembl chrNW_004936769:1,424,549...1,447,516
JBrowse link
regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chrNW_004936512:6,652,836...6,666,171
Ensembl chrNW_004936512:6,653,777...6,666,758
JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:22884333 RGD:9686419 NCBI chrNW_004936480:17,051,902...17,416,335
Ensembl chrNW_004936480:17,051,898...17,413,657
JBrowse link
G Trpc5 transient receptor potential cation channel subfamily C member 5 ISO RGD PMID:21179559 RGD:10043832 NCBI chrNW_004936499:3,391,386...3,541,406
Ensembl chrNW_004936499:3,343,669...3,543,035
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17417
    biological regulation 11394
      regulation of biological quality 3050
        regulation of membrane potential 519
          membrane hyperpolarization 22
            negative regulation of membrane hyperpolarization 3
            positive regulation of membrane hyperpolarization 5
            regulation of membrane hyperpolarization + 10
paths to the root