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ONTOLOGY REPORT - ANNOTATIONS

Term:membrane hyperpolarization
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Accession:GO:0060081 term browser browse the term
Definition:The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.


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membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:17001300 RGD:6903222 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680 		JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:11,067,016...11,185,480
Ensembl chr 5:11,067,692...11,185,480 		JBrowse link
G CASP1 caspase 1, apoptosis-related cysteine peptidase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:35,188,066...35,199,364
Ensembl chr 9:35,186,420...35,200,328 		JBrowse link
G CFTR CF transmembrane conductance regulator involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr18:28,627,717...28,818,209
Ensembl chr18:28,627,728...28,817,950 		JBrowse link
G CNTF ciliary neurotrophic factor ISO in fast-twitch flexor digitorum brevis muscle fibers RGD PMID:15831538 RGD:1626125 NCBI chr 2:12,492,777...12,495,401
Ensembl chr 2:12,493,169...12,496,159 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:65,439,336...65,442,207
Ensembl chr 5:65,439,336...65,442,207 		JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:38,326,408...38,535,826
Ensembl chr 5:38,326,414...38,533,110 		JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:17091490 RGD:2326042 NCBI chr 4:90,421,956...90,457,406
Ensembl chr 4:90,422,025...90,457,406 		JBrowse link
G KCNQ2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO MGI MGI:62459 NCBI chr17:62,459,277...62,506,403
Ensembl chr17:62,459,281...62,506,424 		JBrowse link
G KCNQ3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:8,669,969...8,978,656
Ensembl chr 4:8,669,121...8,970,342 		JBrowse link
G KCTD7 potassium channel tetramerization domain containing 7 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:16,382,333...16,393,861
Ensembl chr 3:16,385,006...16,393,841 		JBrowse link
G PARK7 Parkinsonism associated deglycase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,516 		JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:15062979 RGD:1642685 NCBI chr 6:64,073,343...64,159,187
Ensembl chr 6:64,068,577...64,163,472 		JBrowse link
G SLC26A3 solute carrier family 26 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,480,629...107,518,771
Ensembl chr 9:107,480,641...107,518,728 		JBrowse link
negative regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRTC1 CREB regulated transcription coactivator 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:59,069,334...59,157,196
Ensembl chr 2:59,069,335...59,157,176 		JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 ISO RGD PMID:28993448 RGD:329848961 NCBI chr 5:11,633,523...11,905,325
Ensembl chr 5:11,633,541...11,903,094 		JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560 		JBrowse link
positive regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO (PMID:15803439), (PMID:17703433) BHF-UCL PMID:15803439 PMID:17703433 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:30408474 RGD:26923909 NCBI chr16:29,439,294...29,808,855
Ensembl chr16:29,439,264...29,808,993 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 involved_in IMP (PMID:25139746) AgBase PMID:25139746 NCBI chr14:79,345,382...80,106,337
Ensembl chr14:79,352,005...80,106,295 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 involved_in IMP (PMID:25139746) AgBase PMID:25139746 NCBI chr13:83,436,343...83,498,419
Ensembl chr13:83,436,395...83,498,478 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in IMP (PMID:25139746) AgBase PMID:25139746 NCBI chr14:41,125,819...41,169,582
Ensembl chr14:41,125,869...41,169,578 		JBrowse link
regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr 5:14,875,524...14,888,224
Ensembl chr 5:14,874,465...14,888,223 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:22884333 RGD:9686419 NCBI chr16:29,439,294...29,808,855
Ensembl chr16:29,439,264...29,808,993 		JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 ISO RGD PMID:21179559 RGD:10043832 NCBI chr  X:91,716,334...91,988,364
Ensembl chr  X:91,721,644...91,988,120 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    biological regulation 13003
      regulation of biological quality 3273
        regulation of membrane potential 532
          membrane hyperpolarization 24
            negative regulation of membrane hyperpolarization 3
            positive regulation of membrane hyperpolarization 5
            regulation of membrane hyperpolarization + 10
paths to the root