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ONTOLOGY REPORT - ANNOTATIONS

Term:membrane hyperpolarization
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Accession:GO:0060081 term browser browse the term
Definition:The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.

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membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:17001300 RGD:6903222 NCBI chrNW_004624772:12,099,523...12,127,437
Ensembl chrNW_004624772:12,099,435...12,127,737 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 acts_upstream_of_or_within ISO (PMID:9065835) MGI PMID:9065835 NCBI chrNW_004624752:11,062,059...11,172,357
Ensembl chrNW_004624752:11,062,002...11,170,406 		JBrowse link
G Cftr CF transmembrane conductance regulator involved_in ISO (PMID:21976599) UniProt PMID:21976599 NCBI chrNW_004624827:1,704,733...1,893,579 JBrowse link
G Cntf ciliary neurotrophic factor ISO in fast-twitch flexor digitorum brevis muscle fibers RGD PMID:15831538 RGD:1626125 NCBI chrNW_004624864:1,785,215...1,788,608
Ensembl chrNW_004624864:1,782,139...1,792,879 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:16236819) BHF-UCL PMID:16236819 NCBI chrNW_004624860:2,042,325...2,045,953
Ensembl chrNW_004624860:2,039,771...2,045,867 		JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 involved_in ISO (PMID:17761775) UniProt PMID:17761775 NCBI chrNW_004624750:22,807,234...22,996,614
Ensembl chrNW_004624750:22,807,370...22,996,753 		JBrowse link
G Kcnj10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:17091490 RGD:2326042 NCBI chrNW_004624794:1,180,822...1,211,781
Ensembl chrNW_004624794:1,180,834...1,212,456 		JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO MGI MGI:62459 NCBI chrNW_004624741:29,089,894...29,143,681
Ensembl chrNW_004624741:29,091,119...29,143,589 		JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within ISO (PMID:19060215) MGI PMID:19060215 NCBI chrNW_004624735:23,441,042...23,752,197
Ensembl chrNW_004624735:23,441,042...23,751,247 		JBrowse link
G Kctd7 potassium channel tetramerization domain containing 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624740:8,588,339...8,609,541
Ensembl chrNW_004624740:8,598,309...8,609,696 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:16624565) MGI PMID:16624565 NCBI chrNW_004624818:3,900,917...3,915,457
Ensembl chrNW_004624818:3,900,917...3,911,042 		JBrowse link
G Prkcz protein kinase C zeta ISO RGD PMID:15062979 RGD:1642685 NCBI chrNW_004624818:7,758,192...7,846,950
Ensembl chrNW_004624818:7,759,770...7,847,208 		JBrowse link
G Slc26a3 solute carrier family 26 member 3 involved_in ISO (PMID:21976599) UniProt PMID:21976599 NCBI chrNW_004624739:21,979,164...22,004,794
Ensembl chrNW_004624739:21,979,172...22,004,716 		JBrowse link
negative regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crtc1 CREB regulated transcription coactivator 1 acts_upstream_of_or_within ISO (PMID:23223304) MGI PMID:23223304 NCBI chrNW_004624908:1,814,079...1,868,717
Ensembl chrNW_004624908:1,814,148...1,866,915 		JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 ISO RGD PMID:28993448 RGD:329848961 NCBI chrNW_004624752:11,766,033...12,027,804
Ensembl chrNW_004624752:11,765,679...12,022,320 		JBrowse link
G Sod2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chrNW_004624855:3,260,800...3,271,864
Ensembl chrNW_004624855:3,260,809...3,271,367 		JBrowse link
positive regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in ISO (PMID:15803439), (PMID:17703433) BHF-UCL PMID:15803439 PMID:17703433 NCBI chrNW_004624775:18,846,222...18,856,093
Ensembl chrNW_004624775:18,849,118...18,855,577 		JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:30408474 RGD:26923909 NCBI chrNW_004624759:9,636,380...10,044,832
Ensembl chrNW_004624759:9,636,457...10,049,403 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chrNW_004624754:10,152,635...10,885,239
Ensembl chrNW_004624754:10,153,809...10,885,079 		JBrowse link
G Trpc1 transient receptor potential cation channel subfamily C member 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chrNW_004624730:19,307,346...19,375,537 JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chrNW_004624747:10,675,625...10,685,351 JBrowse link
regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chrNW_004624816:3,334,934...3,348,355
Ensembl chrNW_004624816:3,334,684...3,347,842 		JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:22884333 RGD:9686419 NCBI chrNW_004624759:9,636,380...10,044,832
Ensembl chrNW_004624759:9,636,457...10,049,403 		JBrowse link
G Trpc5 transient receptor potential cation channel subfamily C member 5 ISO RGD PMID:21179559 RGD:10043832 NCBI chrNW_004624803:3,494,311...3,812,985
Ensembl chrNW_004624803:3,666,276...3,813,401 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17653
    biological regulation 11854
      regulation of biological quality 3014
        regulation of membrane potential 500
          membrane hyperpolarization 23
            negative regulation of membrane hyperpolarization 3
            positive regulation of membrane hyperpolarization 5
            regulation of membrane hyperpolarization + 10
paths to the root