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ONTOLOGY REPORT - ANNOTATIONS

Term:membrane hyperpolarization
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Accession:GO:0060081 term browser browse the term
Definition:The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.


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membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:17001300 RGD:6903222 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261 		JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr22:36,560,857...36,703,752
Ensembl chr22:36,560,857...36,703,752 		JBrowse link
G CASP1 caspase 1 acts_upstream_of_or_within ISO (PMID:23028046) MGI PMID:23028046 NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250 		JBrowse link
G CFTR CF transmembrane conductance regulator involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971 		JBrowse link
G CNTF ciliary neurotrophic factor ISO in fast-twitch flexor digitorum brevis muscle fibers RGD PMID:15831538 RGD:1626125 NCBI chr11:58,622,665...58,625,733
Ensembl chr11:58,622,665...58,625,733 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IMP (PMID:16236819) BHF-UCL PMID:16236819 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788 		JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:75,040,078...75,209,839
Ensembl chr12:75,040,077...75,209,839 		JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:17091490 RGD:2326042 NCBI chr 1:160,037,467...160,070,160
Ensembl chr 1:159,998,651...160,070,483 		JBrowse link
G KCNQ2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO MGI MGI:62459 NCBI chr20:63,400,208...63,472,655
Ensembl chr20:63,400,208...63,472,677 		JBrowse link
G KCNQ3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:132,120,861...132,481,095
Ensembl chr 8:132,120,861...132,481,095 		JBrowse link
G KCTD7 potassium channel tetramerization domain containing 7 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:66,628,881...66,643,229
Ensembl chr 7:66,628,881...66,649,067 		JBrowse link
G PARK7 Parkinsonism associated deglycase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:15062979 RGD:1642685 NCBI chr 1:2,048,504...2,185,395
Ensembl chr 1:2,050,411...2,185,395 		JBrowse link
G SLC26A3 solute carrier family 26 member 3 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:107,765,469...107,803,223
Ensembl chr 7:107,765,467...107,803,225 		JBrowse link
negative regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRTC1 CREB regulated transcription coactivator 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:18,683,680...18,782,333
Ensembl chr19:18,683,678...18,782,333 		JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:28993448 GO_REF:0000107 RGD:329848961 NCBI chr22:35,738,736...36,028,824
Ensembl chr22:35,738,736...36,028,824 		JBrowse link
G SOD2 superoxide dismutase 2 involved_in ISO
IEA		 RGD
Ensembl		 PMID:20529999 GO_REF:0000107 RGD:27095884 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
positive regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in IMP (PMID:15803439), (PMID:17703433) BHF-UCL PMID:15803439 PMID:17703433 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:30408474 GO_REF:0000107 RGD:26923909 NCBI chr 5:45,254,948...45,696,380
Ensembl chr 5:45,254,948...45,696,498 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr10:76,869,602...77,637,808
Ensembl chr10:76,869,601...77,638,369 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr 3:142,724,034...142,807,888
Ensembl chr 3:142,724,034...142,807,888 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406 		JBrowse link
regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr12:48,814,480...48,828,941
Ensembl chr12:48,813,794...48,828,941 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:22884333 GO_REF:0000107 RGD:9686419 NCBI chr 5:45,254,948...45,696,380
Ensembl chr 5:45,254,948...45,696,498 		JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 involved_in ISO
IEA		 RGD
Ensembl		 PMID:21179559 GO_REF:0000107 RGD:10043832 NCBI chr  X:111,768,011...112,082,776
Ensembl chr  X:111,768,011...112,082,776 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 27142
    biological regulation 13699
      regulation of biological quality 3694
        regulation of membrane potential 560
          membrane hyperpolarization 24
            negative regulation of membrane hyperpolarization 3
            positive regulation of membrane hyperpolarization 5
            regulation of membrane hyperpolarization + 10
paths to the root