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ONTOLOGY REPORT - ANNOTATIONS


Term:membrane hyperpolarization
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Accession:GO:0060081 term browser browse the term
Definition:The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.


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membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:17001300 RGD:6903222 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054
JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:19,263,950...19,406,952
Ensembl chr19:19,267,426...19,406,883
JBrowse link
G CASP1 caspase 1 acts_upstream_of_or_within ISO (PMID:23028046) MGI PMID:23028046 NCBI chr 1:96,389,697...96,400,610
Ensembl chr 1:96,389,657...96,400,849
JBrowse link
G CFTR CF transmembrane conductance regulator involved_in ISO (PMID:21976599) UniProt PMID:21976599 NCBI chr21:86,154,313...86,332,436 JBrowse link
G CNTF ciliary neurotrophic factor ISO in fast-twitch flexor digitorum brevis muscle fibers RGD PMID:15831538 RGD:1626125 NCBI chr 1:14,724,562...14,730,698
Ensembl chr 1:14,728,383...14,730,150
JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:5,085,221...5,088,135
Ensembl chr11:5,085,518...5,087,335
JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:70,603,034...70,770,625
Ensembl chr11:70,603,003...70,768,859
JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:17091490 RGD:2326042 NCBI chr20:3,873,915...3,907,587
Ensembl chr20:3,902,513...3,903,652
JBrowse link
G KCNQ2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO MGI MGI:62459 NCBI chr 2:739,965...803,575
Ensembl chr 2:761,952...802,999
JBrowse link
G KCNQ3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:126,566,288...126,921,354
Ensembl chr 8:126,566,545...126,622,712
JBrowse link
G KCTD7 potassium channel tetramerization domain containing 7 involved_in IEA TreeGrafter
Ensembl
GO_REF:0000107 GO_REF:0000118 NCBI chr28:2,255,817...2,276,616
Ensembl chr28:2,256,743...2,271,099
JBrowse link
G PARK7 Parkinsonism associated deglycase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:123,776,084...123,808,031
Ensembl chr20:123,776,297...123,798,434
JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:15062979 RGD:1642685 NCBI chr20:129,367,309...129,502,681
Ensembl chr20:129,365,679...129,485,818
JBrowse link
G SLC26A3 solute carrier family 26 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:76,682,255...76,739,460
Ensembl chr21:76,681,951...76,721,139
JBrowse link
negative regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRTC1 CREB regulated transcription coactivator 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:17,146,954...17,246,209 JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 ISO RGD PMID:28993448 RGD:329848961 NCBI chr19:18,507,184...18,801,535 JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974
JBrowse link
positive regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO (PMID:15803439), (PMID:17703433) BHF-UCL PMID:15803439 PMID:17703433 NCBI chr25:67,964,840...67,977,006
Ensembl chr25:67,962,401...67,973,324
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:30408474 RGD:26923909 NCBI chr 4:44,029,173...44,443,669 JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr 9:53,727,790...54,557,252
Ensembl chr 9:54,182,910...54,554,716
JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr15:47,827,295...47,909,207
Ensembl chr15:47,827,247...47,909,202
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr11:105,020,972...105,072,660 JBrowse link
regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr11:45,056,116...45,071,076
Ensembl chr11:45,061,046...45,071,544
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:22884333 RGD:9686419 NCBI chr 4:44,029,173...44,443,669 JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 ISO RGD PMID:21179559 RGD:10043832 NCBI chr  X:99,546,923...99,856,971
Ensembl chr  X:99,550,595...99,736,668
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19829
    biological regulation 12152
      regulation of biological quality 3221
        regulation of membrane potential 526
          membrane hyperpolarization 24
            negative regulation of membrane hyperpolarization 3
            positive regulation of membrane hyperpolarization 5
            regulation of membrane hyperpolarization + 10
paths to the root