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ONTOLOGY REPORT - ANNOTATIONS

Term:membrane hyperpolarization
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Accession:GO:0060081 term browser browse the term
Definition:The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.


show annotations for term's descendants           Sort by:
membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:17001300 RGD:6903222 NCBI chr17:53,828,482...53,847,043
Ensembl chr17:53,813,976...53,847,167 		JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:27,750,314...27,862,646
Ensembl chr10:27,750,935...27,862,885 		JBrowse link
G CFTR CF transmembrane conductance regulator involved_in ISS UniProt GO_REF:0000024 NCBI chr14:56,290,417...56,452,919
Ensembl chr14:56,290,275...56,453,977 		JBrowse link
G CNTF ciliary neurotrophic factor ISO in fast-twitch flexor digitorum brevis muscle fibers RGD PMID:15831538 RGD:1626125 NCBI chr18:37,758,148...37,765,698 JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:16236819) BHF-UCL PMID:16236819 NCBI chr27:39,808,987...39,810,789
Ensembl chr27:39,756,363...39,811,035 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in IEA Ensembl GO_REF:0000107
G KCNC2 potassium voltage-gated channel subfamily C member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:15,599,428...15,822,579
Ensembl chr10:15,643,962...15,818,097 		JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:17091490 RGD:2326042 NCBI chr38:22,114,718...22,143,625
Ensembl chr38:22,130,508...22,140,813 		JBrowse link
G KCNQ2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO MGI MGI:62459 NCBI chr24:47,060,527...47,089,077
Ensembl chr24:47,060,245...47,089,711 		JBrowse link
G KCNQ3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr13:28,765,472...29,062,371
Ensembl chr13:28,773,738...29,062,370 		JBrowse link
G KCTD7 potassium channel tetramerization domain containing 7 involved_in ISO (PMID:27742667) UniProt PMID:27742667
G PARK7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:16624565) MGI PMID:16624565 NCBI chr 5:61,576,219...61,592,325
Ensembl chr 5:61,576,069...61,592,303 		JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:15062979 RGD:1642685 NCBI chr 5:57,012,020...57,113,346
Ensembl chr 5:57,012,070...57,112,664 		JBrowse link
G SLC26A3 solute carrier family 26 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:12,817,177...12,843,502
Ensembl chr18:12,808,806...12,843,076 		JBrowse link
negative regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRTC1 CREB regulated transcription coactivator 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:44,315,021...44,394,385
Ensembl chr20:44,319,858...44,394,599 		JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 ISO RGD PMID:28993448 RGD:329848961 NCBI chr10:28,284,836...28,494,618
Ensembl chr10:28,192,683...28,489,114 		JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chr 1:48,943,472...48,955,158
Ensembl chr 1:48,836,262...48,955,706 		JBrowse link
positive regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO (PMID:15803439), (PMID:17703433) BHF-UCL PMID:15803439 PMID:17703433 NCBI chr 4:8,681,192...8,694,059
Ensembl chr 4:8,683,798...8,693,880 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:30408474 RGD:26923909 NCBI chr 4:64,777,069...65,162,603
Ensembl chr 4:64,775,577...65,160,444 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr 4:26,844,250...27,338,271
Ensembl chr 4:26,844,250...27,555,776 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr23:38,350,066...38,416,086
Ensembl chr23:38,350,278...38,414,464 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr26:17,293,334...17,330,156
Ensembl chr26:17,262,100...17,330,165 		JBrowse link
regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:22884333 RGD:9686419 NCBI chr 4:64,777,069...65,162,603
Ensembl chr 4:64,775,577...65,160,444 		JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 ISO RGD PMID:21179559 RGD:10043832 NCBI chr  X:84,835,130...84,989,609
Ensembl chr  X:84,801,096...85,116,625 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22141
    biological regulation 12559
      regulation of biological quality 3369
        regulation of membrane potential 538
          membrane hyperpolarization 24
            negative regulation of membrane hyperpolarization 3
            positive regulation of membrane hyperpolarization 5
            regulation of membrane hyperpolarization + 10
paths to the root