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ONTOLOGY REPORT - ANNOTATIONS

Term:membrane hyperpolarization
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Accession:GO:0060081 term browser browse the term
Definition:The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.


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membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO RGD PMID:17001300 RGD:6903222 NCBI chr 1:86,162,401...86,193,883
Ensembl chr 1:121,212,488...121,243,099 		JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr22:17,475,693...17,618,299
Ensembl chr22:35,317,121...35,454,850 		JBrowse link
G CASP1 caspase 1 acts_upstream_of_or_within ISO (PMID:23028046) MGI PMID:23028046 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G CFTR CF transmembrane conductance regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864 		JBrowse link
G CNTF ciliary neurotrophic factor ISO in fast-twitch flexor digitorum brevis muscle fibers RGD PMID:15831538 RGD:1626125 NCBI chr11:53,876,081...53,882,870
Ensembl chr11:57,336,792...57,341,121 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 involved_in ISO (PMID:16236819) BHF-UCL PMID:16236819 NCBI chr12:5,165,057...5,168,307 JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 involved_in ISO (PMID:17761775) UniProt PMID:17761775 NCBI chr12:72,566,924...72,736,270 JBrowse link
G KCNJ10 potassium inwardly rectifying channel subfamily J member 10 ISO RGD PMID:17091490 RGD:2326042 NCBI chr 1:135,391,321...135,424,100 JBrowse link
G KCNQ2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO MGI MGI:62459 Ensembl chr20:61,325,365...61,395,266 JBrowse link
G KCNQ3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:128,769,930...129,134,671
Ensembl chr 8:131,755,454...131,815,237 		JBrowse link
G KCTD7 potassium channel tetramerization domain containing 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:59,392,366...59,435,993
Ensembl chr 7:73,687,952...73,697,728 		JBrowse link
G PARK7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO (PMID:16624565) MGI PMID:16624565 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G PRKCZ protein kinase C zeta ISO RGD PMID:15062979 RGD:1642685 NCBI chr 1:763,942...901,531
Ensembl chr 1:1,920,219...2,045,855 		JBrowse link
G SLC26A3 solute carrier family 26 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:99,747,405...99,776,763
Ensembl chr 7:112,470,041...112,507,671 		JBrowse link
negative regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRTC1 CREB regulated transcription coactivator 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr19:18,123,375...18,221,832
Ensembl chr19:19,131,484...19,228,980 		JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 ISO RGD PMID:28993448 RGD:329848961 NCBI chr22:16,740,707...17,031,415
Ensembl chr22:34,586,044...34,870,257 		JBrowse link
G SOD2 superoxide dismutase 2 ISO RGD PMID:20529999 RGD:27095884 NCBI chr 6:157,562,814...157,610,155
Ensembl chr 6:162,576,082...162,589,960 		JBrowse link
positive regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen involved_in ISO (PMID:15803439), (PMID:17703433) BHF-UCL PMID:15803439 PMID:17703433 NCBI chr 1:206,252,141...206,263,830
Ensembl chr 1:211,279,015...211,291,044 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:30408474 RGD:26923909 NCBI chr 5:64,673,392...65,116,259
Ensembl chr 5:69,724,767...70,158,761 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr10:73,391,297...74,158,488
Ensembl chr10:76,062,047...76,820,644 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr 3:139,757,408...139,841,006
Ensembl chr 3:147,349,056...147,432,332 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:25139746) AgBase PMID:25139746 NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182 		JBrowse link
regulation of membrane hyperpolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 ISO RGD PMID:15024042 RGD:13514097 NCBI chr12:39,918,022...39,931,386
Ensembl chr12:40,797,293...40,811,409 		JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 ISO RGD PMID:22884333 RGD:9686419 NCBI chr 5:64,673,392...65,116,259
Ensembl chr 5:69,724,767...70,158,761 		JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 ISO RGD PMID:21179559 RGD:10043832 NCBI chr  X:100,886,122...101,191,425
Ensembl chr  X:111,346,804...111,648,201 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    biological regulation 11853
      regulation of biological quality 3156
        regulation of membrane potential 524
          membrane hyperpolarization 24
            negative regulation of membrane hyperpolarization 3
            positive regulation of membrane hyperpolarization 5
            regulation of membrane hyperpolarization + 10
paths to the root