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ONTOLOGY REPORT - ANNOTATIONS

Term:sodium ion homeostasis
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Accession:GO:0055078 term browser browse the term
Definition:Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.


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sodium ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 involved_in ISO (PMID:9838244) BHF-UCL PMID:9838244 NCBI chr 4:1,365,725...1,373,138 JBrowse link
G EDNRA endothelin receptor type A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:81,210,750...81,279,053
Ensembl chr 8:81,209,327...81,276,853 		JBrowse link
G EDNRB endothelin receptor type B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:50,073,300...50,102,879
Ensembl chr11:50,072,554...50,102,884 		JBrowse link
G EXT1 exostosin glycosyltransferase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:20,645,002...20,935,769
Ensembl chr 4:20,645,610...20,935,540 		JBrowse link
G EXT2 exostosin glycosyltransferase 2 acts_upstream_of_or_within ISO (PMID:31365577) MGI PMID:31365577 NCBI chr 2:18,099,790...18,239,229
Ensembl chr 2:18,209,102...18,232,025 		JBrowse link
G MC3R melanocortin 3 receptor ISO RGD PMID:19570553 RGD:6484660 NCBI chr17:56,868,525...56,869,605
Ensembl chr17:56,868,525...56,869,605 		JBrowse link
G SCN7A sodium voltage-gated channel alpha subunit 7 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:72,946,147...73,026,656
Ensembl chr15:72,945,288...73,026,656 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:64,287,529...64,312,917
Ensembl chr 5:64,285,015...64,313,612 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta acts_upstream_of_or_within
involved_in 		IEA Ensembl GO_REF:0000107 NCBI chr 3:22,832,259...22,902,592
Ensembl chr 3:22,832,262...22,902,063 		JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:22,977,940...23,013,384
Ensembl chr 3:22,977,947...23,013,384 		JBrowse link
G SLC12A1 solute carrier family 12 member 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:123,481,892...123,571,655
Ensembl chr 1:123,481,369...123,571,630 		JBrowse link
G SLC12A2 solute carrier family 12 member 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:131,016,430...131,109,307
Ensembl chr 2:131,016,418...131,109,299 		JBrowse link
G SLC12A3 solute carrier family 12 member 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:18,844,752...18,885,497
Ensembl chr 6:18,844,600...18,885,476 		JBrowse link
G SLC9B2 solute carrier family 9 member B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:117,996,777...118,049,430
Ensembl chr 8:117,997,128...118,046,506 		JBrowse link
G UMOD uromodulin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:25,473,048...25,492,286
Ensembl chr 3:25,473,162...25,492,278 		JBrowse link
G UPK3A uroplakin 3A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:4,109,985...4,122,272
Ensembl chr 5:4,109,938...4,119,289 		JBrowse link
intracellular sodium ion homeostasis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen ISO RGD PMID:16380540 RGD:1582118 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:16380540 RGD:1582118 NCBI chr  X:95,267,709...95,272,237
Ensembl chr  X:95,269,300...95,270,388 		JBrowse link
G ATP12A ATPase H+/K+ transporting non-gastric alpha2 subunit involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:113,901...144,765
Ensembl chr11:114,325...144,092 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 involved_in IDA
IBA
IEA 		(PMID:19542013) ComplexPortal
GO_Central
Ensembl		 PMID:19542013 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,506...104,384,680 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:90,341,316...90,371,040
Ensembl chr 4:90,341,322...90,370,996 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:49,905,851...49,927,437
Ensembl chr 6:49,905,847...49,927,633 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 involved_in IDA
IBA
IEA 		(PMID:19542013) ComplexPortal
GO_Central
Ensembl		 PMID:19542013 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:81,912,543...81,937,015
Ensembl chr 4:81,911,561...81,991,840 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:52,925,697...52,932,638
Ensembl chr12:52,925,693...52,932,635 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:82,680,442...82,727,052 JBrowse link
G ATP4A ATPase H+/K+ transporting subunit alpha involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:44,984,014...45,057,796
Ensembl chr 6:44,984,233...44,997,552 		JBrowse link
G ATP4B ATPase H+/K+ transporting subunit beta involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:78,780,013...78,785,143
Ensembl chr11:78,780,013...78,785,116 		JBrowse link
G C7 complement C7 ISO RGD PMID:10792960 RGD:1599525 NCBI chr16:25,846,860...25,902,707
Ensembl chr16:25,846,860...25,903,980 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 involved_in IDA (PMID:19542013) ComplexPortal PMID:19542013 NCBI chr 9:45,165,314...45,172,440 JBrowse link
G IL1A interleukin 1 alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:43,718,320...43,731,668
Ensembl chr 3:43,718,368...43,731,121 		JBrowse link
G LOC100157711 sodium/potassium-transporting ATPase subunit alpha-4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 4:90,291,281...90,319,590
Ensembl chr 4:90,290,394...90,332,760 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 acts_upstream_of_or_within ISO (PMID:9689096) MGI PMID:9689096 NCBI chr 8:80,303,172...80,669,050
Ensembl chr 8:80,312,234...80,668,412 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:64,287,529...64,312,917
Ensembl chr 5:64,285,015...64,313,612 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:22,832,259...22,902,592
Ensembl chr 3:22,832,262...22,902,063 		JBrowse link
G SCNN1D sodium channel epithelial 1 subunit delta involved_in ISO (PMID:16423824) ComplexPortal PMID:16423824 NCBI chr 6:63,568,171...63,578,623 JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:22,977,940...23,013,384
Ensembl chr 3:22,977,947...23,013,384 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 ISO RGD PMID:11250940 RGD:628514 NCBI chr 1:29,625,786...29,753,619
Ensembl chr 1:29,745,114...29,753,602 		JBrowse link
G SLC12A2 solute carrier family 12 member 2 acts_upstream_of_or_within ISO (PMID:11940530) ARUK-UCL PMID:11940530 NCBI chr 2:131,016,430...131,109,307
Ensembl chr 2:131,016,418...131,109,299 		JBrowse link
G SLC1A3 solute carrier family 1 member 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:21,873,691...21,965,315
Ensembl chr16:21,873,691...21,964,990 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:99,823,503...100,257,306
Ensembl chr 3:99,897,162...100,244,759 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:84,373,921...84,426,447
Ensembl chr 6:84,372,649...84,426,997 		JBrowse link
G SPP1 secreted phosphoprotein 1 acts_upstream_of_or_within ISO (PMID:17898038) MGI PMID:17898038 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340 		JBrowse link
G TMPRSS3 transmembrane serine protease 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr13:205,707,501...205,733,037
Ensembl chr13:205,709,663...205,732,824 		JBrowse link
G UMOD uromodulin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:25,473,048...25,492,286
Ensembl chr 3:25,473,162...25,492,278 		JBrowse link
negative regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPX spexin hormone involved_in ISO PMID:22038051 UniProt PMID:22038051 RGD:8693358 NCBI chr 5:51,919,474...51,929,204
Ensembl chr 5:51,920,400...51,941,598 		JBrowse link
positive regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DRD2 dopamine receptor D2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599 		JBrowse link
G EDN1 endothelin 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
regulation of renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORIN corin, serine peptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:37,530,812...37,811,226
Ensembl chr 8:37,530,815...37,809,761 		JBrowse link
renal sodium excretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6V1B1 ATPase H+ transporting V1 subunit B1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:71,560,102...71,591,885
Ensembl chr 3:71,561,236...71,591,845 		JBrowse link
G COMT catechol-O-methyltransferase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:51,384,729...51,403,997
Ensembl chr14:51,385,738...51,403,998 		JBrowse link
G EDNRB endothelin receptor type B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:50,073,300...50,102,879
Ensembl chr11:50,072,554...50,102,884 		JBrowse link
G MLLT6 MLLT6, PHD finger containing acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:23,380,190...23,404,853
Ensembl chr12:23,380,209...23,404,837 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 acts_upstream_of_or_within ISO (PMID:9689096) MGI PMID:9689096 NCBI chr 8:80,303,172...80,669,050
Ensembl chr 8:80,312,234...80,668,412 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    homeostatic process 1938
      chemical homeostasis 1178
        inorganic ion homeostasis 565
          sodium ion homeostasis 46
            intracellular sodium ion homeostasis + 28
            renal sodium excretion + 9
Path 2
Term Annotations click to browse term
  biological_process 18944
    homeostatic process 1938
      chemical homeostasis 1178
        monoatomic ion homeostasis 644
          monoatomic cation homeostasis 630
            sodium ion homeostasis 46
              intracellular sodium ion homeostasis + 28
              renal sodium excretion + 9
paths to the root