Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:membrane depolarization
go back to main search page
Accession:GO:0051899 term browser browse the term
Definition:The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
Synonyms:xref: Reactome:R-HSA-112308 "Presynaptic depolarization and calcium channel opening"


show annotations for term's descendants           Sort by:
membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IMP RGD PMID:16644907 RGD:1625443 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Asic3 acid sensing ion channel subunit 3 involved_in IDA
ISO		 PMID:11120882
(PMID:9744806)		 RGD PMID:9744806 PMID:11120882 RGD:596936209 NCBI chr 4:11,652,946...11,657,415
Ensembl chr 4:10,760,597...10,764,643 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 acts_upstream_of_or_within ISO
IEA		 MGI:2451291 (PMID:30819023)
GO_REF:0000107		 RGD
Ensembl		 PMID:30819023 GO_REF:0000107 NCBI chr13:87,261,964...87,286,911
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 acts_upstream_of_or_within ISO MGI:3696954 (PMID:30819023) RGD PMID:30819023 NCBI chr 1:89,700,645...89,729,782
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Best2 bestrophin 2 involved_in ISO (PMID:16912113) RGD PMID:16912113 NCBI chr19:40,047,191...40,053,216
Ensembl chr19:23,141,602...23,148,339 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856209|MGI:1856210|MGI:1856211 (PMID:10908603), (PMID:11718712), (PMID:8158221) RGD PMID:8158221 PMID:10908603 PMID:11718712 NCBI chr19:40,425,560...40,724,810
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 acts_upstream_of_or_within ISO
IEA		 MGI:1856548 (PMID:9065835)
GO_REF:0000107		 RGD
Ensembl		 PMID:9065835 GO_REF:0000107 NCBI chr 7:111,451,605...111,579,071
Ensembl chr 7:109,574,459...109,697,227 		JBrowse link
G Cav1 caveolin 1 acts_upstream_of_or_within ISO
IEA		 MGI:2180364 (PMID:17098833)
GO_REF:0000107		 RGD
Ensembl		 PMID:17098833 GO_REF:0000107 NCBI chr 4:46,606,538...46,639,616
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Chrna1 cholinergic receptor nicotinic alpha 1 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:78,862,286...78,877,353
Ensembl chr 3:58,454,744...58,469,840 		JBrowse link
G Chrna10 cholinergic receptor nicotinic alpha 10 subunit involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 1:165,898,932...165,905,348
Ensembl chr 1:156,487,279...156,491,476 		JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:44,517,862...44,534,144
Ensembl chr15:40,342,317...40,358,601 		JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:64,297,755...64,311,251
Ensembl chr 8:55,401,702...55,415,165 		JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1926251|MGI:2158758|MGI:87891 (PMID:11222635), (PMID:11226318), (PMID:12944511), (PMID:15741168)		 GO_Central
RGD		 PMID:11222635 PMID:11226318 PMID:12944511 PMID:15741168 GO_REF:0000033 NCBI chr 3:188,506,802...188,535,558
Ensembl chr 3:168,136,266...168,156,957 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000107
MGI:2179133 (PMID:12944511)		 GO_Central
Ensembl
RGD		 PMID:12944511 GO_REF:0000033 GO_REF:0000107 NCBI chr16:71,400,615...71,407,315
Ensembl chr16:64,697,741...64,704,441 		JBrowse link
G Chrna9 cholinergic receptor nicotinic alpha 9 subunit involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr14:42,588,948...42,595,669
Ensembl chr14:42,235,226...42,242,192 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:54,999,943...55,015,137
Ensembl chr10:54,501,093...54,516,345 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1926253 (PMID:11222635)		 GO_Central
RGD		 PMID:11222635 GO_REF:0000033 NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:71,411,847...71,454,225
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 8:64,312,644...64,333,319
Ensembl chr 8:55,418,313...55,437,027 		JBrowse link
G Chrnd cholinergic receptor nicotinic delta subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:95,310,316...95,318,734
Ensembl chr 9:87,862,407...87,870,833 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:55,829,835...55,838,853
Ensembl chr10:55,331,212...55,335,530 		JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:95,325,984...95,332,092
Ensembl chr 9:87,878,085...87,914,482 		JBrowse link
G Cnga1 cyclic nucleotide gated channel subunit alpha 1 IDA RGD PMID:18048449 RGD:6902904 NCBI chr14:35,920,948...35,959,065
Ensembl chr14:35,567,125...35,605,065 		JBrowse link
G Cnga2 cyclic nucleotide gated channel subunit alpha 2 involved_in IDA PMID:1697649 RGD
UniProt		 PMID:18048449 PMID:1697649 RGD:6902904, RGD:1298763 NCBI chr  X:154,741,742...154,759,814
Ensembl chr  X:149,696,997...149,715,051 		JBrowse link
G Cnga3 cyclic nucleotide gated channel subunit alpha 3 involved_in IDA PMID:15178415 UniProt PMID:15178415 RGD:405650286 NCBI chr 9:46,943,353...46,989,862
Ensembl chr 9:39,448,034...39,493,183 		JBrowse link
G Cngb1 cyclic nucleotide gated channel subunit beta 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr19:9,732,646...9,798,864
Ensembl chr19:9,726,595...9,791,173 		JBrowse link
G Edn1 endothelin 1 IMP RGD PMID:15655307 RGD:1580292 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 acts_upstream_of_or_within ISO MGI:2176347 (PMID:17245443) RGD PMID:17245443 NCBI chr11:40,655,974...41,056,966
Ensembl chr11:27,169,740...27,570,645 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in TAS PMID:12514208 UniProt PMID:12514208 RGD:728711 NCBI chr 1:6,878,542...7,273,447
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit IDA induced in pulmonary artery smooth muscle cells RGD PMID:11571252 RGD:2290591 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kmt2a lysine methyltransferase 2A IEP RGD PMID:20211609 RGD:9588219 NCBI chr 8:54,013,547...54,089,219
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in ISO (PMID:9016352) RGD PMID:9016352 NCBI chr12:39,505,438...39,523,349
Ensembl chr12:33,844,396...33,862,253 		JBrowse link
G P2rx7 purinergic receptor P2X 7 involved_in ISO
IDA		 (PMID:9038151)
PMID:8614837		 RGD PMID:9038151 PMID:8614837 RGD:69918 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Park7 Parkinsonism associated deglycase acts_upstream_of_or_within ISO MGI:3579140 (PMID:16624565) RGD PMID:16624565 NCBI chr 5:166,636,551...166,659,825
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Phox2b paired-like homeobox 2b IEP RGD PMID:19036978 RGD:152025257 NCBI chr14:41,420,011...41,424,527
Ensembl chr14:41,066,264...41,068,978 		JBrowse link
G Prkcz protein kinase C, zeta IMP RGD PMID:15381257 RGD:1642699 NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IEA		 (PMID:21051419)
GO_REF:0000107		 RGD
Ensembl		 PMID:21051419 GO_REF:0000107 NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO
IEA		 (PMID:21051419)
GO_REF:0000107		 RGD
Ensembl		 PMID:21051419 GO_REF:0000107 NCBI chr 8:49,527,529...49,550,019
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:14500339), (PMID:21051419), (PMID:21895525)		 BHF-UCL
Ensembl
RGD		 PMID:14500339 PMID:21051419 PMID:21895525 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 involved_in IDA PMID:14642278 UniProt PMID:14642278 RGD:8553687 NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
membrane depolarization during action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1g calcium voltage-gated channel subunit alpha1 G involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:14,894,630...14,952,317
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,716,266...113,827,670
Ensembl chr 7:111,836,012...111,944,688 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 involved_in ISO (PMID:7604285) RGD PMID:7604285 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 involved_in ISO
IEA
IBA
ISS		 (PMID:23115331)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:23115331 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:128,228,424...128,340,749
Ensembl chr 8:119,350,724...119,462,614 		JBrowse link
G Scn11a sodium voltage-gated channel alpha subunit 11 involved_in ISO
IBA
IEA
IDA		 (PMID:12384689), (PMID:24036948), (PMID:24776970)
GO_REF:0000033
(PMID:24036948)
GO_REF:0000107
PMID:10196578		 RGD
GO_Central
Ensembl		 PMID:12384689 PMID:24036948 PMID:24776970 PMID:10196578 GO_REF:0000033 GO_REF:0000107, RGD:69980 NCBI chr 8:128,374,441...128,444,718
Ensembl chr 8:119,496,769...119,567,044 		JBrowse link
G Scn1a sodium voltage-gated channel alpha subunit 1 involved_in ISO
IBA
IEA
ISS		 (PMID:14672992)
GO_REF:0000033
(PMID:27281198)
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:14672992 PMID:27281198 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:71,360,840...71,479,870
Ensembl chr 3:50,952,791...51,071,699 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IEA		 (PMID:35277491)
GO_REF:0000107		 RGD
Ensembl		 PMID:35277491 GO_REF:0000107 NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Scn2a sodium voltage-gated channel alpha subunit 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:70,710,862...70,845,569
Ensembl chr 3:50,302,877...50,437,214 		JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in ISO
IEA		 (PMID:35277491)
GO_REF:0000107		 RGD
Ensembl		 PMID:35277491 GO_REF:0000107 NCBI chr 8:54,322,383...54,334,519
Ensembl chr 8:45,425,629...45,437,765 		JBrowse link
G Scn3a sodium voltage-gated channel alpha subunit 3 involved_in ISO
IBA
IEA		 (PMID:35277491)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:35277491 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:50,146,411...50,258,119
Ensembl chr 3:50,148,139...50,258,119 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO
IEA		 (PMID:20042427), (PMID:20226894), (PMID:21051419)
GO_REF:0000107		 RGD
Ensembl		 PMID:20042427 PMID:20226894 PMID:21051419 GO_REF:0000107 NCBI chr 8:49,527,529...49,550,019
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn4a sodium voltage-gated channel alpha subunit 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:91,745,459...91,796,452
Ensembl chr10:91,246,936...91,296,545 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000107
GO_REF:0000033
(PMID:14500339), (PMID:18065446), (PMID:22529811)		 BHF-UCL
Ensembl
GO_Central
RGD		 PMID:14500339 PMID:18065446 PMID:22529811 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Scn7a sodium voltage-gated channel alpha subunit 7 NOT|involved_in IDA PMID:9001394 UniProt PMID:9001394 RGD:61747 NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256 		JBrowse link
G Scn8a sodium voltage-gated channel alpha subunit 8 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:133,860,901...134,034,809
Ensembl chr 7:131,982,480...132,151,292 		JBrowse link
G Scn9a sodium voltage-gated channel alpha subunit 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:51,145,148...51,293,342
Ensembl chr 3:51,145,146...51,293,516 		JBrowse link
G Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:16728661)		 BHF-UCL
Ensembl
RGD		 PMID:16728661 GO_REF:0000024 GO_REF:0000107 NCBI chr14:81,920,819...81,930,202
Ensembl chr14:77,696,333...77,705,741 		JBrowse link
membrane depolarization during atrial cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO
ISS		 (PMID:17224476)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:17224476 GO_REF:0000024 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17224476)		 BHF-UCL
Ensembl
RGD		 PMID:17224476 GO_REF:0000024 GO_REF:0000107 NCBI chr17:82,473,097...82,818,564
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA		 (PMID:18065446)
GO_REF:0000107		 RGD
Ensembl		 PMID:18065446 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
membrane depolarization during AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISS
ISO		 GO_REF:0000024
(PMID:26253506)		 BHF-UCL
RGD		 PMID:26253506 GO_REF:0000024 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G involved_in ISS GO_REF:0000024 BHF-UCL GO_REF:0000024 NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 involved_in ISO
IEA
ISS		 (PMID:17224476)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
BHF-UCL		 PMID:17224476 GO_REF:0000024 GO_REF:0000107 NCBI chr17:82,473,097...82,818,564
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA
ISS		 (PMID:18616619)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
BHF-UCL		 PMID:18616619 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA		 (PMID:27207958)
GO_REF:0000107		 RGD
Ensembl		 PMID:27207958 GO_REF:0000107 NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
membrane depolarization during bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 involved_in ISO
IEA		 (PMID:21383000)
GO_REF:0000107		 RGD
Ensembl		 PMID:21383000 GO_REF:0000107 NCBI chr 4:19,902,324...20,330,287
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA
ISS		 (PMID:18065446)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
BHF-UCL		 PMID:18065446 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA		 (PMID:27207958)
GO_REF:0000107		 RGD
Ensembl		 PMID:27207958 GO_REF:0000107 NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C involved_in ISO
ISS		 (PMID:15454078)
GO_REF:0000024		 RGD
BHF-UCL		 PMID:15454078 GO_REF:0000024 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in IC PMID:21859974 BHF-UCL PMID:21859974 RGD:6767284 NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:128,228,424...128,340,749
Ensembl chr 8:119,350,724...119,462,614 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IEA
IBA		 (PMID:19808477)
GO_REF:0000107
GO_REF:0000033
(PMID:17884088)		 RGD
Ensembl
GO_Central		 PMID:17884088 PMID:19808477 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in ISO
IEA
IBA		 (PMID:19808477)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:19808477 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:54,322,383...54,334,519
Ensembl chr 8:45,425,629...45,437,765 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO
IEA
IBA		 (PMID:21051419)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:21051419 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:49,527,529...49,550,019
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn4b sodium voltage-gated channel beta subunit 4 involved_in ISO
IBA		 (PMID:17592081)
GO_REF:0000033		 RGD
GO_Central		 PMID:17592081 GO_REF:0000033 NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA
ISS
IMP		 (PMID:21895525)
GO_REF:0000107
GO_REF:0000024
PMID:29457789		 RGD
Ensembl
BHF-UCL		 PMID:21895525 PMID:29457789 GO_REF:0000024 GO_REF:0000107, RGD:126781740 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
membrane depolarization during Purkinje myocyte cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IEA		 (PMID:18464934)
GO_REF:0000107		 RGD
Ensembl		 PMID:18464934 GO_REF:0000107 NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:22766342)		 BHF-UCL
Ensembl
RGD		 PMID:22766342 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO
IEA		 (PMID:27207958)
GO_REF:0000107		 RGD
Ensembl		 PMID:27207958 GO_REF:0000107 NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
membrane depolarization during SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1d calcium voltage-gated channel subunit alpha1 D involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:21131953)
MGI:2180141 (PMID:12700358)
GO_REF:0000107		 RGD
Ensembl		 PMID:12700358 PMID:21131953 GO_REF:0000107 NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G involved_in ISS GO_REF:0000024 BHF-UCL GO_REF:0000024 NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 involved_in ISO
IEA		 (PMID:16407510)
GO_REF:0000107		 RGD
Ensembl		 PMID:16407510 GO_REF:0000107 NCBI chr 8:68,118,062...68,155,482
Ensembl chr 8:59,221,653...59,259,639 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:18616619)		 BHF-UCL
Ensembl
RGD		 PMID:18616619 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5if1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) RGD PMID:24005319 NCBI chr 5:150,022,960...150,026,677
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Casp1 caspase 1 acts_upstream_of_or_within ISO (PMID:23028046) RGD PMID:23028046 NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Cck cholecystokinin IDA RGD PMID:11964411 RGD:625521 NCBI chr 8:130,031,012...130,037,702
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:25217637) RGD PMID:25217637 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain acts_upstream_of_or_within ISO
IEA		 MGI:2145814|MGI:2153356 (PMID:19293339), (PMID:19519726), (PMID:24852368)
GO_REF:0000107		 RGD
Ensembl		 PMID:19293339 PMID:19519726 PMID:24852368 GO_REF:0000107 NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO (PMID:20885443) RGD PMID:20885443 NCBI chr 3:188,572,345...188,631,391
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Kcnq3 potassium voltage-gated channel subfamily Q member 3 acts_upstream_of_or_within ISO
IEA		 (PMID:20885443)
GO_REF:0000107		 RGD
Ensembl		 PMID:20885443 GO_REF:0000107 NCBI chr 7:99,614,089...99,914,736
Ensembl chr 7:97,730,465...98,025,653 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of ISO MGI:2386080 (PMID:16198349) RGD PMID:16198349 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Ppif peptidylprolyl isomerase F acts_upstream_of_or_within ISO MGI:88459 (PMID:19293339) RGD PMID:19293339 NCBI chr16:1,264,001...1,270,722
Ensembl chr16:1,257,106...1,263,913 		JBrowse link
negative regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO
IEA		 (PMID:25257915)
GO_REF:0000107		 RGD
Ensembl		 PMID:25257915 GO_REF:0000107 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
negative regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:16153637)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:16153637 GO_REF:0000024 GO_REF:0000107 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Bok BCL2 family apoptosis regulator BOK involved_in ISO
IEA		 (PMID:27098698)
GO_REF:0000107		 RGD
Ensembl		 PMID:27098698 GO_REF:0000107 NCBI chr 9:101,670,729...101,681,834
Ensembl chr 9:94,223,389...94,234,476 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 IMP RGD PMID:29215467 RGD:13504824 NCBI chr 1:252,306,541...252,337,622
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Hsh2d hematopoietic SH2 domain containing acts_upstream_of_or_within ISO
IEA		 (PMID:15569688)
GO_REF:0000107		 RGD
Ensembl		 PMID:15569688 GO_REF:0000107 NCBI chr16:17,664,548...17,686,976
Ensembl chr16:17,635,322...17,647,991 		JBrowse link
G Ngfr nerve growth factor receptor IMP RGD PMID:19457114 RGD:5508731 NCBI chr10:81,012,077...81,030,305
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Rbfox2 RNA binding fox-1 homolog 2 IMP RGD PMID:34731606 RGD:329845875 NCBI chr 7:110,691,230...110,934,901
Ensembl chr 7:108,810,628...109,054,691 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
positive regulation of membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C IMP RGD PMID:18562674 RGD:152177517 NCBI chr 4:153,431,169...154,051,932
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D IDA RGD PMID:7760845 RGD:70680 NCBI chr16:5,233,682...5,527,549
Ensembl chr16:5,228,306...5,668,215 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 IMP RGD PMID:16641242 RGD:401959318 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
positive regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 involved_in IMP
IDA		 PMID:18180363
PMID:15579534		 BHF-UCL PMID:18180363 PMID:15579534 RGD:6767295, RGD:6484228 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300 		JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO (PMID:18184654) RGD PMID:18184654 NCBI chr10:54,176,325...54,177,696
Ensembl chr10:53,677,467...53,678,840 		JBrowse link
positive regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31172217 RGD:329403053 NCBI chr13:80,280,595...80,366,939
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IMP RGD PMID:15564577 RGD:2313870 NCBI chr10:55,456,923...55,469,239
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Dcn decorin acts_upstream_of_or_within ISO UniProtKB:P35968 (PMID:23798385) RGD PMID:23798385 NCBI chr 7:34,167,973...34,208,004
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Kdr kinase insert domain receptor acts_upstream_of_or_within ISO
IEA		 UniProtKB:P07585 (PMID:23798385)
GO_REF:0000107		 RGD
Ensembl		 PMID:23798385 GO_REF:0000107 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor involved_in ISO
IEA
IBA
ISS		 (PMID:18852119)
GO_REF:0000107
GO_REF:0000033
GO_REF:0000024		 RGD
Ensembl
GO_Central
UniProt		 PMID:18852119 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199 		JBrowse link
G Myoc myocilin involved_in ISO
IEA
ISS		 (PMID:17516541)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17516541 GO_REF:0000024 GO_REF:0000107 NCBI chr13:77,509,963...77,520,361
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:19139380 RGD:2305938 NCBI chr 1:254,547,311...254,589,596
Ensembl chr 1:244,598,292...244,634,359 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (PMID:16198349) RGD PMID:16198349 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 IMP protein:increased activity:brain: RGD PMID:21616968 RGD:10413888 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISO (PMID:19767770) RGD PMID:19767770 NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Tspo translocator protein IDA RGD PMID:15183124 RGD:2317155 NCBI chr 7:116,600,214...116,610,461
Ensembl chr 7:114,720,188...114,730,450 		JBrowse link
positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IMP RGD PMID:20826763 RGD:10003037 NCBI chr 1:104,918,462...104,949,453
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
regulation of atrial cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1g calcium voltage-gated channel subunit alpha1 G acts_upstream_of_or_within ISO
IEA		 MGI:2182962 (PMID:16690884)
GO_REF:0000107		 RGD
Ensembl		 PMID:16690884 GO_REF:0000107 NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,355,008...79,422,752 		JBrowse link
G Fhl1 four and a half LIM domains 1 involved_in ISO (PMID:18281375) RGD PMID:18281375 NCBI chr  X:139,592,794...139,652,290
Ensembl chr  X:134,555,479...134,614,928 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177 (PMID:10969038) RGD PMID:10969038 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja5 gap junction protein, alpha 5 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:22247482), (PMID:23348765)
GO_REF:0000107
MGI:2445238 (PMID:10515563), (PMID:10969038), (PMID:9501070)		 RGD
Ensembl		 PMID:9501070 PMID:10515563 PMID:10969038 PMID:22247482 PMID:23348765 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Mir26a microRNA 26a acts_upstream_of ISO (PMID:23543060) RGD PMID:23543060 NCBI chr 8:127,633,048...127,633,137
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:20062061), (PMID:21041692)
GO_REF:0000107
MGI:2180183 (PMID:20062061)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:20062061 PMID:21041692 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:128,228,424...128,340,749
Ensembl chr 8:119,350,724...119,462,614 		JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 involved_in ISO
IEA		 (PMID:19808477), (PMID:22247482)
GO_REF:0000107		 RGD
Ensembl		 PMID:19808477 PMID:22247482 GO_REF:0000107 NCBI chr 1:95,481,298...95,491,211
Ensembl chr 1:86,353,917...86,363,739 		JBrowse link
G Scn2b sodium voltage-gated channel beta subunit 2 involved_in ISO
IEA		 (PMID:19808477)
GO_REF:0000107		 RGD
Ensembl		 PMID:19808477 GO_REF:0000107 NCBI chr 8:54,322,383...54,334,519
Ensembl chr 8:45,425,629...45,437,765 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO
IEA		 (PMID:21051419)
GO_REF:0000107
(PMID:19796257)		 RGD
Ensembl		 PMID:19796257 PMID:21051419 GO_REF:0000107 NCBI chr 8:49,527,529...49,550,019
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IBA
IEA
ISS		 (PMID:19167345), (PMID:22247482)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
BHF-UCL		 PMID:19167345 PMID:22247482 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Tbx5 T-box transcription factor 5 acts_upstream_of_positive_effect ISO
IEA		 UniProtKB:Q9JJV9 (PMID:22728936)
GO_REF:0000107		 RGD
Ensembl		 PMID:22728936 GO_REF:0000107 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
regulation of membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B2m beta-2 microglobulin involved_in ISO (PMID:23144825) RGD PMID:23144825 NCBI chr 3:129,549,236...129,555,354
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in ISO (PMID:22514276) RGD PMID:22514276 NCBI chr 2:217,698,324...217,961,898
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Cftr CF transmembrane conductance regulator NOT|involved_in ISO (PMID:24885604) RGD PMID:24885604 NCBI chr 4:47,422,084...47,694,646
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Fgf12 fibroblast growth factor 12 involved_in IDA PMID:12401812 BHF-UCL PMID:12401812 RGD:6484231 NCBI chr11:85,501,947...86,069,543
Ensembl chr11:71,997,099...72,562,607 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 involved_in IDA
IEA
ISO
IBA		 GO_REF:0000107
(PMID:16043489)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:16043489 PMID:20806410 GO_REF:0000033 GO_REF:0000107, RGD:9686372 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:10,620,422...10,639,457
Ensembl chr 7:9,970,368...9,988,841 		JBrowse link
G Hcn3 hyperpolarization-activated cyclic nucleotide-gated potassium channel 3 involved_in IBA
ISO		 GO_REF:0000033
(PMID:16043489)		 GO_Central
RGD		 PMID:16043489 GO_REF:0000033 NCBI chr 2:176,849,635...176,867,726
Ensembl chr 2:174,551,680...174,565,966 		JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 involved_in IEA
ISO
IBA		 GO_REF:0000107
(PMID:12750403), (PMID:16043489)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:12750403 PMID:16043489 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:68,118,062...68,155,482
Ensembl chr 8:59,221,653...59,259,639 		JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:15217910)
GO_REF:0000107		 RGD
Ensembl		 PMID:15217910 GO_REF:0000107 NCBI chr18:60,663,918...60,996,824
Ensembl chr18:58,393,509...58,723,137 		JBrowse link
G Npff neuropeptide FF-amide peptide precursor IDA RGD PMID:17289819 RGD:2316567 NCBI chr 7:135,533,050...135,533,839 JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:15120846 RGD:9743930 NCBI chr 3:187,983,778...188,033,934
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO
IEA		 (PMID:23420830)
GO_REF:0000107		 RGD
Ensembl		 PMID:23420830 GO_REF:0000107 NCBI chr10:54,176,325...54,177,696
Ensembl chr10:53,677,467...53,678,840 		JBrowse link
regulation of membrane depolarization during action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in IMP PMID:8816717 UniProt PMID:8816717 RGD:405650388 NCBI chr11:93,702,382...93,716,059
Ensembl chr11:80,198,153...80,211,657 		JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 involved_in ISO (PMID:16930557) RGD PMID:16930557 NCBI chr 5:76,703,687...76,822,584
Ensembl chr 5:71,911,135...72,065,443 		JBrowse link
regulation of membrane depolarization during cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO
IEA		 (PMID:17275750)
GO_REF:0000107		 RGD
Ensembl		 PMID:17275750 GO_REF:0000107 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO
IEA		 MGI:2445238 (PMID:9501070)
GO_REF:0000107		 RGD
Ensembl		 PMID:9501070 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Rangrf RAN guanine nucleotide release factor involved_in ISO
IBA		 (PMID:21621375)
GO_REF:0000033		 RGD
GO_Central		 PMID:21621375 GO_REF:0000033 NCBI chr10:54,176,325...54,177,696
Ensembl chr10:53,677,467...53,678,840 		JBrowse link
G Slmap sarcolemma associated protein involved_in ISO
IBA		 (PMID:23064965)
GO_REF:0000033		 RGD
GO_Central		 PMID:23064965 GO_REF:0000033 NCBI chr16:1,673,964...1,791,902
Ensembl chr16:1,667,208...1,785,149 		JBrowse link
regulation of mitochondrial depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcd1 ATP binding cassette subfamily D member 1 involved_in ISO (PMID:25583114) RGD PMID:25583114 NCBI chr  X:156,579,669...156,601,448
Ensembl chr  X:151,428,578...151,450,115 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit acts_upstream_of_or_within ISO
IEA		 MGI:104995 (PMID:15288121)
GO_REF:0000107		 RGD
Ensembl		 PMID:15288121 GO_REF:0000107 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit acts_upstream_of_or_within ISO
IEA		 MGI:104990 (PMID:15288121)
GO_REF:0000107		 RGD
Ensembl		 PMID:15288121 GO_REF:0000107 NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO
IEA		 (PMID:22736029)
GO_REF:0000107		 RGD
Ensembl		 PMID:22736029 GO_REF:0000107 NCBI chr 7:124,706,246...124,867,234
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma acts_upstream_of_or_within ISO
IEA		 MGI:3759678 (PMID:16129705)
GO_REF:0000107		 RGD
Ensembl		 PMID:16129705 GO_REF:0000107 NCBI chr 6:78,382,849...78,406,037
Ensembl chr 6:72,647,025...72,672,491 		JBrowse link
regulation of ventricular cardiac muscle cell membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 involved_in ISO
IEA		 (PMID:17060380)
GO_REF:0000107		 RGD
Ensembl		 PMID:17060380 GO_REF:0000107 NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Gja1 gap junction protein, alpha 1 acts_upstream_of_or_within ISO MGI:1857177|MGI:95716 (PMID:10969038), (PMID:9109444) RGD PMID:9109444 PMID:10969038 NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja5 gap junction protein, alpha 5 acts_upstream_of_or_within ISO
IEA		 MGI:2445238|MGI:95713 (PMID:10515563), (PMID:10969038), (PMID:9501070)
GO_REF:0000107
(PMID:26786475)		 RGD
Ensembl		 PMID:9501070 PMID:10515563 PMID:10969038 PMID:26786475 GO_REF:0000107 NCBI chr 2:187,291,227...187,310,770
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Gpd1l glycerol-3-phosphate dehydrogenase 1 like involved_in ISO (PMID:17967977), (PMID:19666841) RGD PMID:17967977 PMID:19666841 NCBI chr 8:123,469,282...123,498,948
Ensembl chr 8:114,588,487...114,620,723 		JBrowse link
G Scn3b sodium voltage-gated channel beta subunit 3 involved_in ISO
IEA		 (PMID:20042427)
GO_REF:0000107		 RGD
Ensembl		 PMID:20042427 GO_REF:0000107 NCBI chr 8:49,527,529...49,550,019
Ensembl chr 8:40,630,455...40,652,868 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 involved_in ISO
IEA
ISS		 (PMID:18065446), (PMID:22529811), (PMID:7889574)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
BHF-UCL		 PMID:7889574 PMID:18065446 PMID:22529811 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:128,098,613...128,196,515
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:18952608)		 Ensembl
RGD		 PMID:18952608 GO_REF:0000107 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological quality 3462
        regulation of membrane potential 545
          membrane depolarization 117
            membrane depolarization during action potential + 32
            mitochondrial depolarization + 31
            negative regulation of membrane depolarization + 8
            positive regulation of membrane depolarization + 17
            regulation of membrane depolarization + 57
            regulation of vascular associated smooth muscle cell membrane depolarization + 1
paths to the root