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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of intracellular pH
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Accession:GO:0051453 term browser browse the term
Definition:Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
Synonyms:exact_synonym: cell pH regulation;   cellular pH regulation;   pH regulation in cell;   regulation of cell pH



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regulation of intracellular pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5F1B ATP synthase F1 subunit beta involved_in IMP (PMID:17510399) UniProt PMID:17510399 NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
JBrowse link
G CA2 carbonic anhydrase 2 involved_in ISS
IBA
IEA
UniProt
GO_Central
Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
JBrowse link
G CA7 carbonic anhydrase 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:66,844,414...66,854,147
Ensembl chr16:66,844,414...66,854,153
JBrowse link
G CHP1 calcineurin like EF-hand protein 1 involved_in IDA (PMID:15035633), (PMID:8901634) UniProt PMID:8901634 PMID:15035633 NCBI chr15:41,231,268...41,281,887
Ensembl chr15:41,230,839...41,281,887
JBrowse link
G CLCNKB chloride voltage-gated channel Kb involved_in ISO (PMID:35349181) UniProt PMID:35349181 NCBI chr 1:16,043,782...16,057,326
Ensembl chr 1:16,040,252...16,057,311
JBrowse link
G HVCN1 hydrogen voltage gated channel 1 involved_in ISO
IMP
IEA
ISS
(PMID:20548053) RGD
UniProt
Ensembl
PMID:20548053 PMID:24935944 GO_REF:0000024 GO_REF:0000107 RGD:14985214 NCBI chr12:110,648,686...110,704,952
Ensembl chr12:110,627,841...110,704,950
JBrowse link
G SLC26A6 solute carrier family 26 member 6 involved_in IDA
IMP
IEA
(PMID:15990874)
(PMID:20501439)
UniProt
Ensembl
PMID:15990874 PMID:20501439 GO_REF:0000107 NCBI chr 3:48,625,723...48,635,461
Ensembl chr 3:48,625,723...48,635,493
JBrowse link
G SLC4A1 solute carrier family 4 member 1 (Diego blood group) involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:44,248,390...44,268,135
Ensembl chr17:44,248,390...44,268,141
JBrowse link
G SLC4A10 solute carrier family 4 member 10 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:161,624,416...161,985,270
Ensembl chr 2:161,424,332...161,985,282
JBrowse link
G SLC4A2 solute carrier family 4 member 2 involved_in ISO
IBA
IEA
RGD
GO_Central
Ensembl
PMID:16440368 GO_REF:0000033 GO_REF:0000107 RGD:9999231 NCBI chr 7:151,058,200...151,076,527
Ensembl chr 7:151,057,210...151,076,526
JBrowse link
G SLC4A3 solute carrier family 4 member 3 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(PMID:2686841) Ensembl
MGI
GO_Central
PMID:2686841 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:219,627,630...219,641,971
Ensembl chr 2:219,627,394...219,641,980
JBrowse link
G SLC4A4 solute carrier family 4 member 4 involved_in
acts_upstream_of
IMP
IBA
ISS
IGI
IDA
(PMID:24453308)
(PMID:21976511)
(PMID:10069984)
ARUK-UCL
GO_Central
PMID:10069984 PMID:21976511 PMID:24453308 GO_REF:0000033 NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087
JBrowse link
G SLC4A5 solute carrier family 4 member 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:74,216,242...74,343,416
Ensembl chr 2:74,216,242...74,343,416
JBrowse link
G SLC4A7 solute carrier family 4 member 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:27,372,723...27,484,384
Ensembl chr 3:27,372,723...27,484,420
JBrowse link
G SLC4A8 solute carrier family 4 member 8 acts_upstream_of_or_within
involved_in
IDA
IBA
IEA
ISS
(PMID:11133997), (PMID:18577713) ARUK-UCL
GO_Central
Ensembl
PMID:11133997 PMID:18577713 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr12:51,391,446...51,515,763
Ensembl chr12:51,391,317...51,515,763
JBrowse link
G SLC4A9 solute carrier family 4 member 9 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:140,360,194...140,375,141
Ensembl chr 5:140,360,194...140,375,141
JBrowse link
G SLC9A1 solute carrier family 9 member A1 involved_in ISO
IBA
IEA
IDA
(PMID:15035633), (PMID:24840010) RGD
GO_Central
Ensembl
BHF-UCL
PMID:15035633 PMID:22387884 PMID:24840010 GO_REF:0000033 GO_REF:0000107 RGD:6771326 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981
JBrowse link
G SLC9A2 solute carrier family 9 member A2 involved_in IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 2:102,619,553...102,711,355
Ensembl chr 2:102,619,553...102,711,355
JBrowse link
G SLC9A3 solute carrier family 9 member A3 involved_in IDA
IBA
(PMID:35613257) UniProt
GO_Central
PMID:35613257 GO_REF:0000033 NCBI chr 5:470,456...524,449
Ensembl chr 5:470,456...524,449
JBrowse link
G SLC9A4 solute carrier family 9 member A4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:102,473,226...102,533,972
Ensembl chr 2:102,473,226...102,533,972
JBrowse link
G SLC9A5 solute carrier family 9 member A5 involved_in IDA
IBA
(PMID:24936055) UniProt
GO_Central
PMID:24936055 GO_REF:0000033 NCBI chr16:67,248,979...67,272,191
Ensembl chr16:67,237,683...67,272,191
JBrowse link
G SLC9A6 solute carrier family 9 member A6 involved_in IMP
IBA
IDA
IEA
(PMID:30296617)
(PMID:28635961)
UniProt
GO_Central
Ensembl
PMID:28635961 PMID:30296617 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:135,973,837...136,047,269
Ensembl chr  X:135,973,841...136,047,269
JBrowse link
G SLC9A7 solute carrier family 9 member A7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr  X:46,599,251...46,759,118
Ensembl chr  X:46,599,251...46,759,118
JBrowse link
G SLC9A8 solute carrier family 9 member A8 involved_in IMP
IBA
IEA
(PMID:34288721) UniProt
GO_Central
Ensembl
PMID:34288721 GO_REF:0000033 GO_REF:0000107 NCBI chr20:49,812,828...49,892,242
Ensembl chr20:49,812,713...49,892,242
JBrowse link
G SLC9A9 solute carrier family 9 member A9 involved_in IEA
IBA
IDA
(PMID:15522866), (PMID:24065030) Ensembl
GO_Central
UniProt
PMID:15522866 PMID:24065030 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:143,265,222...143,848,468
Ensembl chr 3:143,265,222...143,848,485
JBrowse link
G SLC9B1 solute carrier family 9 member B1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:102,885,049...103,019,705
Ensembl chr 4:102,885,048...103,019,719
JBrowse link
G SLC9C1 solute carrier family 9 member C1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:112,140,898...112,294,216
Ensembl chr 3:112,140,898...112,294,227
JBrowse link
G SLC9C2 solute carrier family 9 member C2 (putative) involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:173,500,460...173,603,072
Ensembl chr 1:173,500,460...173,603,072
JBrowse link
G TM9SF4 transmembrane 9 superfamily member 4 involved_in IMP (PMID:19893578) UniProt PMID:19893578 NCBI chr20:32,109,714...32,167,256
Ensembl chr20:32,109,714...32,167,258
JBrowse link
G TP53 tumor protein p53 ISO RGD PMID:16688778 RGD:1598619 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546
JBrowse link
endosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16107722) Ensembl
MGI
PMID:16107722 GO_REF:0000107 NCBI chr11:77,589,953...77,610,356
Ensembl chr11:77,589,391...77,610,356
JBrowse link
G ATP6AP1 ATPase H+ transporting accessory protein 1 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr  X:154,428,677...154,436,516
Ensembl chr  X:154,428,633...154,436,516
JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr17:42,458,878...42,522,579
Ensembl chr17:42,458,844...42,522,582
JBrowse link
G ATP6V0B ATPase H+ transporting V0 subunit b involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 1:43,974,960...43,978,295
Ensembl chr 1:43,974,487...43,978,295
JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218
JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,746,770...113,812,056
JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265
JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 7:128,862,856...128,865,847
Ensembl chr 7:128,862,856...128,865,847
JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558
JBrowse link
G CLCN3 chloride voltage-gated channel 3 involved_in TAS (PMID:12471024) UniProt PMID:12471024 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673
JBrowse link
G FASLG Fas ligand involved_in ISO
IEA
RGD
Ensembl
PMID:18045865 GO_REF:0000107 RGD:2315735 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
JBrowse link
G RNASEK ribonuclease K involved_in IPI
NAS
(PMID:26212330)
(PMID:32001091)
UniProt
ComplexPortal
PMID:26212330 PMID:32001091 NCBI chr17:7,012,624...7,014,532
Ensembl chr17:7,012,417...7,014,532
JBrowse link
G TMEM9 transmembrane protein 9 involved_in IDA (PMID:30374053) UniProt PMID:30374053 NCBI chr 1:201,134,772...201,171,558
Ensembl chr 1:201,134,772...201,171,574
JBrowse link
Golgi lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP1 ATPase H+ transporting accessory protein 1 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr  X:154,428,677...154,436,516
Ensembl chr  X:154,428,633...154,436,516
JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G ATP6V0A2 ATPase H+ transporting V0 subunit a2 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr12:123,712,353...123,761,755
Ensembl chr12:123,712,353...123,761,755
JBrowse link
G ATP6V0B ATPase H+ transporting V0 subunit b involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 1:43,974,960...43,978,295
Ensembl chr 1:43,974,487...43,978,295
JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218
JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,746,770...113,812,056
JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265
JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 7:128,862,856...128,865,847
Ensembl chr 7:128,862,856...128,865,847
JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558
JBrowse link
G RNASEK ribonuclease K involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr17:7,012,624...7,014,532
Ensembl chr17:7,012,417...7,014,532
JBrowse link
intracellular pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CFTR CF transmembrane conductance regulator involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:117,480,025...117,668,665
Ensembl chr 7:117,287,120...117,715,971
JBrowse link
G SLC26A3 solute carrier family 26 member 3 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:107,765,469...107,803,223
Ensembl chr 7:107,765,467...107,803,225
JBrowse link
G SLC26A6 solute carrier family 26 member 6 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:48,625,723...48,635,461
Ensembl chr 3:48,625,723...48,635,493
JBrowse link
intracellular pH reduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP1 ATPase H+ transporting accessory protein 1 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr  X:154,428,677...154,436,516
Ensembl chr  X:154,428,633...154,436,516
JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G ATP6V0A4 ATPase H+ transporting V0 subunit a4 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 7:138,706,294...138,798,196
Ensembl chr 7:138,706,294...138,799,560
JBrowse link
G ATP6V0B ATPase H+ transporting V0 subunit b involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 1:43,974,960...43,978,295
Ensembl chr 1:43,974,487...43,978,295
JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218
JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,746,770...113,812,056
JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265
JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 7:128,862,856...128,865,847
Ensembl chr 7:128,862,856...128,865,847
JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558
JBrowse link
G GPR89A G protein-coupled receptor 89A involved_in IDA
IBA
(PMID:18794847) UniProt
GO_Central
PMID:18794847 GO_REF:0000033 NCBI chr 1:145,607,988...145,670,650
Ensembl chr 1:145,607,988...145,670,650
Ensembl chr 1:145,607,988...145,670,650
JBrowse link
G GPR89B G protein-coupled receptor 89B involved_in IDA
IBA
(PMID:18794847) UniProt
GO_Central
PMID:18794847 GO_REF:0000033 NCBI chr 1:147,928,420...148,025,934
Ensembl chr 1:147,928,393...147,993,592
Ensembl chr 1:147,928,393...147,993,592
JBrowse link
G RNASEK ribonuclease K involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr17:7,012,624...7,014,532
Ensembl chr17:7,012,417...7,014,532
JBrowse link
G SLC12A5 solute carrier family 12 member 5 involved_in ISO
IEA
RGD
Ensembl
PMID:16420452 GO_REF:0000107 RGD:2303953 NCBI chr20:46,021,686...46,060,150
Ensembl chr20:46,021,690...46,060,150
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23908015) Ensembl
MGI
PMID:23908015 GO_REF:0000107 NCBI chr11:68,039,025...68,053,762
Ensembl chr11:68,039,025...68,050,895
JBrowse link
G TPCN2 two pore segment channel 2 involved_in IDA
IEA
(PMID:27140606) UniProt
Ensembl
PMID:27140606 GO_REF:0000107 NCBI chr11:69,048,932...69,090,597
Ensembl chr11:69,048,932...69,136,316
JBrowse link
G TTPA alpha tocopherol transfer protein ISO RGD PMID:22147702 RGD:7247589 NCBI chr 8:63,058,409...63,086,053
Ensembl chr 8:63,048,553...63,086,053
JBrowse link
lysosomal lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP1 ATPase H+ transporting accessory protein 1 involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr  X:154,428,677...154,436,516
Ensembl chr  X:154,428,633...154,436,516
JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IMP
NAS
(PMID:32276428)
(PMID:32001091), (PMID:33065002)
UniProt
ComplexPortal
PMID:32001091 PMID:32276428 PMID:33065002 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 involved_in NAS (PMID:33065002) ComplexPortal PMID:33065002 NCBI chr17:42,458,878...42,522,579
Ensembl chr17:42,458,844...42,522,582
JBrowse link
G ATP6V0B ATPase H+ transporting V0 subunit b involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 1:43,974,960...43,978,295
Ensembl chr 1:43,974,487...43,978,295
JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218
JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A involved_in NAS
IC
(PMID:32001091), (PMID:33065002) ComplexPortal
UniProt
PMID:32001091 PMID:33065002 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,746,770...113,812,056
JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265
JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 7:128,862,856...128,865,847
Ensembl chr 7:128,862,856...128,865,847
JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558
JBrowse link
G CCDC115 coiled-coil domain containing 115 involved_in IMP (PMID:28296633) UniProt PMID:28296633 NCBI chr 2:130,337,933...130,342,681
Ensembl chr 2:130,337,933...130,342,699
JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IMP
IBA
(PMID:11722572) UniProt
GO_Central
PMID:11722572 GO_REF:0000033 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575
JBrowse link
G CLN5 CLN5 intracellular trafficking protein involved_in IMP (PMID:11722572) UniProt PMID:11722572 NCBI chr13:76,992,081...77,005,117
Ensembl chr13:76,990,660...77,019,143
JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IMP (PMID:11722572) UniProt PMID:11722572 NCBI chr15:68,206,992...68,257,211
Ensembl chr15:68,206,992...68,257,211
JBrowse link
G CREG1 cellular repressor of E1A stimulated genes 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:33966596) Ensembl
MGI
PMID:33966596 GO_REF:0000107 NCBI chr 1:167,541,013...167,553,762
Ensembl chr 1:167,529,117...167,553,805
JBrowse link
G GRN granulin precursor involved_in IMP (PMID:28073925) UniProt PMID:28073925 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
G LAMP1 lysosomal associated membrane protein 1 involved_in IDA (PMID:37390818) UniProt PMID:37390818 NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672
JBrowse link
G LAMP2 lysosomal associated membrane protein 2 involved_in IDA (PMID:37390818) UniProt PMID:37390818 NCBI chr  X:120,426,148...120,469,349
Ensembl chr  X:120,426,148...120,469,365
JBrowse link
G PPT1 palmitoyl-protein thioesterase 1 involved_in IMP (PMID:11722572) UniProt PMID:11722572 NCBI chr 1:40,071,461...40,097,252
Ensembl chr 1:40,072,710...40,097,260
JBrowse link
G RNASEK ribonuclease K involved_in NAS (PMID:32001091), (PMID:33065002) ComplexPortal PMID:32001091 PMID:33065002 NCBI chr17:7,012,624...7,014,532
Ensembl chr17:7,012,417...7,014,532
JBrowse link
G SNAPIN SNAP associated protein involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:20920792) Ensembl
MGI
PMID:20920792 GO_REF:0000107 NCBI chr 1:153,658,654...153,661,852
Ensembl chr 1:153,658,703...153,661,852
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr11:68,039,025...68,053,762
Ensembl chr11:68,039,025...68,050,895
JBrowse link
G TMEM106B transmembrane protein 106B involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:28728022) Ensembl
MGI
PMID:28728022 GO_REF:0000107 NCBI chr 7:12,211,294...12,243,367
Ensembl chr 7:12,211,270...12,243,367
JBrowse link
G TMEM199 transmembrane protein 199 involved_in IMP (PMID:28296633) UniProt PMID:28296633 NCBI chr17:28,357,647...28,363,683
Ensembl chr17:28,357,642...28,363,683
JBrowse link
G TMEM9 transmembrane protein 9 involved_in IDA (PMID:30374053) UniProt PMID:30374053 NCBI chr 1:201,134,772...201,171,558
Ensembl chr 1:201,134,772...201,171,574
JBrowse link
lysosomal lumen pH elevation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IDA (PMID:10924275) UniProt PMID:10924275 NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575
JBrowse link
G OCA2 OCA2 melanosomal transmembrane protein involved_in IDA (PMID:25513726), (PMID:32966160) UniProt PMID:25513726 PMID:32966160 NCBI chr15:27,719,008...28,099,315
Ensembl chr15:27,754,875...28,099,315
JBrowse link
G SLC45A2 solute carrier family 45 member 2 involved_in ISS
IEA
IDA
(PMID:32966160) UniProt
Ensembl
PMID:32966160 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:33,944,623...33,984,693
Ensembl chr 5:33,944,623...33,984,693
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IDA (PMID:35333573), (PMID:35750034), (PMID:37390818) UniProt PMID:35333573 PMID:35750034 PMID:37390818 NCBI chr 4:932,460...958,656
Ensembl chr 4:932,387...958,656
JBrowse link
negative regulation of cellular pH reduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator involved_in IDA (PMID:10506221) UniProt PMID:10506221 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
phagosome acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RAB20 RAB20, member RAS oncogene family involved_in IMP (PMID:21255211) UniProt PMID:21255211 NCBI chr13:110,523,066...110,561,722
Ensembl chr13:110,523,066...110,561,722
JBrowse link
G RAB38 RAB38, member RAS oncogene family involved_in IMP (PMID:21255211) UniProt PMID:21255211 NCBI chr11:87,803,715...88,175,443
Ensembl chr11:88,113,251...88,175,443
JBrowse link
G RAB39A RAB39A, member RAS oncogene family involved_in IMP (PMID:21255211) UniProt PMID:21255211 NCBI chr11:107,928,448...107,963,482
Ensembl chr11:107,928,448...107,963,482
JBrowse link
G RAB7A RAB7A, member RAS oncogene family involved_in IMP (PMID:21255211) UniProt PMID:21255211 NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942
JBrowse link
G SLAMF8 SLAM family member 8 acts_upstream_of_or_within ISS UniProt GO_REF:0000024 NCBI chr 1:159,826,873...159,837,492
Ensembl chr 1:159,826,811...159,837,492
JBrowse link
G SLC4A7 solute carrier family 4 member 7 involved_in IDA (PMID:29779931) UniProt PMID:29779931 NCBI chr 3:27,372,723...27,484,384
Ensembl chr 3:27,372,723...27,484,420
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19549681) Ensembl
MGI
PMID:19549681 GO_REF:0000107 NCBI chr11:68,039,025...68,053,762
Ensembl chr11:68,039,025...68,050,895
JBrowse link
positive regulation of cellular pH reduction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AVP arginine vasopressin involved_in ISO
IEA
RGD
Ensembl
PMID:17762181 GO_REF:0000107 RGD:2300343 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724
JBrowse link
G AVPR1A arginine vasopressin receptor 1A involved_in ISO
IEA
RGD
Ensembl
PMID:17762181 GO_REF:0000107 RGD:2300343 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201
JBrowse link
G AVPR1B arginine vasopressin receptor 1B ISO RGD PMID:17762181 RGD:2300343 NCBI chr 1:206,106,936...206,117,388
Ensembl chr 1:206,106,936...206,117,699
JBrowse link
G CA2 carbonic anhydrase 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:23881097) RGD
MGI
Ensembl
PMID:9665810 PMID:23881097 GO_REF:0000107 RGD:1342423 NCBI chr 8:85,464,007...85,481,493
Ensembl chr 8:85,463,968...85,481,493
JBrowse link
G CA7 carbonic anhydrase 7 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:23881097) Ensembl
MGI
PMID:23881097 GO_REF:0000107 NCBI chr16:66,844,414...66,854,147
Ensembl chr16:66,844,414...66,854,153
JBrowse link
positive regulation of Golgi lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UBE3A ubiquitin protein ligase E3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:25,333,728...25,439,056
Ensembl chr15:25,333,728...25,439,051
JBrowse link
regulation of Golgi lumen acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC9A7 solute carrier family 9 member A7 involved_in IMP (PMID:30335141) UniProt PMID:30335141 NCBI chr  X:46,599,251...46,759,118
Ensembl chr  X:46,599,251...46,759,118
JBrowse link
G SLC9A8 solute carrier family 9 member A8 involved_in IDA (PMID:15522866) UniProt PMID:15522866 NCBI chr20:49,812,828...49,892,242
Ensembl chr20:49,812,713...49,892,242
JBrowse link
regulation of lysosomal lumen pH term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LRRK2 leucine rich repeat kinase 2 involved_in IMP (PMID:22012985) ParkinsonsUK-UCL PMID:22012985 NCBI chr12:40,224,997...40,369,285
Ensembl chr12:40,196,744...40,369,285
JBrowse link
G SPNS1 SPNS lysolipid transporter 1, lysophospholipid involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:36161949) Ensembl
MGI
PMID:36161949 GO_REF:0000107 NCBI chr16:28,974,778...28,984,765
Ensembl chr16:28,974,221...28,984,548
JBrowse link
G TASL TLR adaptor interacting with endolysosomal SLC15A4 involved_in IDA
IBA
(PMID:31001245) UniProt
GO_Central
PMID:31001245 GO_REF:0000033 NCBI chr  X:30,558,809...30,577,766
Ensembl chr  X:30,558,809...30,577,766
JBrowse link
G TMEM165 transmembrane protein 165 involved_in IMP (PMID:23569283) UniProt PMID:23569283 NCBI chr 4:55,395,957...55,453,397
Ensembl chr 4:55,395,957...55,453,397
JBrowse link
G TMEM175 transmembrane protein 175 involved_in IEA
IDA
(PMID:35750034) Ensembl
UniProt
PMID:35750034 GO_REF:0000107 NCBI chr 4:932,460...958,656
Ensembl chr 4:932,387...958,656
JBrowse link
G VPS33A VPS33A core subunit of CORVET and HOPS complexes involved_in IMP (PMID:28013294) UniProt PMID:28013294 NCBI chr12:122,229,564...122,266,494
Ensembl chr12:122,229,564...122,266,502
JBrowse link
vacuolar acidification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP1 ATPase H+ transporting accessory protein 1 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr  X:154,428,677...154,436,516
Ensembl chr  X:154,428,633...154,436,516
JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848
JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 involved_in TAS
IBA
(PMID:22982048) ParkinsonsUK-UCL
GO_Central
PMID:22982048 GO_REF:0000033 NCBI chr17:42,458,878...42,522,579
Ensembl chr17:42,458,844...42,522,582
JBrowse link
G ATP6V0A2 ATPase H+ transporting V0 subunit a2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:123,712,353...123,761,755
Ensembl chr12:123,712,353...123,761,755
JBrowse link
G ATP6V0A4 ATPase H+ transporting V0 subunit a4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:138,706,294...138,798,196
Ensembl chr 7:138,706,294...138,799,560
JBrowse link
G ATP6V0B ATPase H+ transporting V0 subunit b involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 1:43,974,960...43,978,295
Ensembl chr 1:43,974,487...43,978,295
JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr16:2,513,726...2,520,218
Ensembl chr16:2,513,952...2,520,218
JBrowse link
G ATP6V0D1 ATPase H+ transporting V0 subunit d1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:67,438,019...67,481,157
Ensembl chr16:67,438,014...67,481,181
JBrowse link
G ATP6V0D2 ATPase H+ transporting V0 subunit d2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:86,098,910...86,154,225
Ensembl chr 8:85,987,323...86,154,225
JBrowse link
G ATP6V0E1 ATPase H+ transporting V0 subunit e1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 5:172,983,771...173,035,445
Ensembl chr 5:172,983,771...173,035,445
JBrowse link
G ATP6V0E2 ATPase H+ transporting V0 subunit e2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:149,872,964...149,880,713
Ensembl chr 7:149,872,968...149,891,204
JBrowse link
G ATP6V1A ATPase H+ transporting V1 subunit A involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 3:113,747,035...113,812,056
Ensembl chr 3:113,746,770...113,812,056
JBrowse link
G ATP6V1B1 ATPase H+ transporting V1 subunit B1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:70,935,900...70,965,431
Ensembl chr 2:70,935,900...70,965,431
JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:20,197,381...20,221,696
Ensembl chr 8:20,197,381...20,230,399
JBrowse link
G ATP6V1D ATPase H+ transporting V1 subunit D involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr14:67,337,872...67,359,804
Ensembl chr14:67,294,371...67,360,265
JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr 7:128,862,856...128,865,847
Ensembl chr 7:128,862,856...128,865,847
JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H involved_in NAS (PMID:32001091), (PMID:9442887) UniProt PMID:9442887 PMID:32001091 NCBI chr 8:53,715,543...53,843,245
Ensembl chr 8:53,715,543...53,843,558
JBrowse link
G CLIC4 chloride intracellular channel 4 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:19197003) Ensembl
MGI
PMID:19197003 GO_REF:0000107 NCBI chr 1:24,745,447...24,844,321
Ensembl chr 1:24,745,382...24,844,321
JBrowse link
G DMXL1 Dmx like 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:119,071,027...119,249,127
Ensembl chr 5:119,037,772...119,249,138
JBrowse link
G DMXL2 Dmx like 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:51,447,791...51,622,771
Ensembl chr15:51,447,711...51,622,833
JBrowse link
G RNASEK ribonuclease K involved_in NAS (PMID:32001091) ComplexPortal PMID:32001091 NCBI chr17:7,012,624...7,014,532
Ensembl chr17:7,012,417...7,014,532
JBrowse link
G SLC11A1 solute carrier family 11 member 1 involved_in
acts_upstream_of_or_within
IEA
ISO
ISS
(PMID:9670047)
(PMID:11067873), (PMID:18984740)
Ensembl
MGI
BHF-UCL
PMID:9670047 PMID:11067873 PMID:18984740 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:218,382,273...218,396,894
Ensembl chr 2:218,382,029...218,396,894
JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in NAS
IBA
(PMID:32001091) ComplexPortal
GO_Central
PMID:32001091 GO_REF:0000033 NCBI chr11:68,039,025...68,053,762
Ensembl chr11:68,039,025...68,050,895
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20484
    biological regulation 13635
      regulation of biological quality 3628
        regulation of intracellular pH 94
          intracellular pH elevation + 7
          intracellular pH reduction + 59
          regulation of cellular pH reduction + 9
          regulation of lysosomal lumen pH + 32
Path 2
Term Annotations click to browse term
  biological_process 20484
    homeostatic process 2115
      chemical homeostasis 1288
        monoatomic ion homeostasis 707
          monoatomic cation homeostasis 693
            regulation of pH 115
              regulation of cellular pH 100
                regulation of intracellular pH 94
                  intracellular pH elevation + 7
                  intracellular pH reduction + 59
                  regulation of cellular pH reduction + 9
                  regulation of lysosomal lumen pH + 32
paths to the root