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ONTOLOGY REPORT - ANNOTATIONS


Term:protein homotetramerization
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Accession:GO:0051289 term browser browse the term
Definition:The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
Synonyms:exact_synonym: protein homotetramer assembly;   protein homotetramer biosynthesis;   protein homotetramer biosynthetic process;   protein homotetramer formation



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protein homotetramerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha involved_in IEA
ISS
(PMID:20952656) Ensembl
UniProt
PMID:20952656 GO_REF:0000024 GO_REF:0000107 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
JBrowse link
G ACACB acetyl-CoA carboxylase beta involved_in IDA (PMID:20952656) UniProt PMID:20952656 NCBI chr12:109,111,189...109,268,226
Ensembl chr12:109,116,587...109,268,226
JBrowse link
G ACOT13 acyl-CoA thioesterase 13 involved_in IPI (PMID:16934754), (PMID:19170545) UniProt PMID:16934754 PMID:19170545 NCBI chr 6:24,667,077...24,705,046
Ensembl chr 6:24,667,035...24,705,065
JBrowse link
G ALDH1A2 aldehyde dehydrogenase 1 family member A2 involved_in IDA (PMID:29240402) UniProt PMID:29240402 NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866
JBrowse link
G ALDH1A3 aldehyde dehydrogenase 1 family member A3 involved_in IDA (PMID:27759097) UniProt PMID:27759097 NCBI chr15:100,879,831...100,916,626
Ensembl chr15:100,861,924...100,916,626
JBrowse link
G ALDH9A1 aldehyde dehydrogenase 9 family member A1 involved_in IDA (PMID:30914451) UniProt PMID:30914451 NCBI chr 1:165,662,216...165,698,562
Ensembl chr 1:165,662,216...165,698,562
JBrowse link
G ALDOA aldolase, fructose-bisphosphate A involved_in ISS UniProt GO_REF:0000024 NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457
JBrowse link
G APIP APAF1 interacting protein involved_in IDA (PMID:24367089) UniProt PMID:24367089 NCBI chr11:34,882,295...34,916,379
Ensembl chr11:34,853,094...34,916,379
JBrowse link
G APPL2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in IDA (PMID:23055524) UniProt PMID:23055524 NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203
JBrowse link
G AQP10 aquaporin 10 involved_in IDA (PMID:30420639) UniProt PMID:30420639 NCBI chr 1:154,321,093...154,325,325
Ensembl chr 1:154,321,090...154,325,325
JBrowse link
G AQP2 aquaporin 2 involved_in IDA (PMID:24733887) UniProt PMID:24733887 NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878
JBrowse link
G AQP4 aquaporin 4 involved_in IDA (PMID:19383790) UniProt PMID:19383790 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771
JBrowse link
G AQP5 aquaporin 5 involved_in IDA (PMID:18768791), (PMID:26569106) UniProt PMID:18768791 PMID:26569106 NCBI chr12:49,961,872...49,965,682
Ensembl chr12:49,961,872...49,965,682
JBrowse link
G B2M beta-2-microglobulin involved_in IPI (PMID:28468825) ARUK-UCL PMID:28468825 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851
JBrowse link
G CBR4 carbonyl reductase 4 involved_in IDA (PMID:19000905) UniProt PMID:19000905 NCBI chr 4:168,894,486...169,010,255
Ensembl chr 4:168,863,770...169,010,275
JBrowse link
G CBY1 chibby 1, beta catenin antagonist involved_in IDA (PMID:21182262) CAFA PMID:21182262 NCBI chr22:38,656,638...38,673,850
Ensembl chr22:38,656,636...38,673,854
JBrowse link
G CRTC1 CREB regulated transcription coactivator 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr19:18,683,680...18,782,333
Ensembl chr19:18,683,678...18,782,333
JBrowse link
G CRTC2 CREB regulated transcription coactivator 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:153,947,675...153,958,612
Ensembl chr 1:153,947,669...153,958,615
JBrowse link
G CRTC3 CREB regulated transcription coactivator 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr15:90,529,923...90,645,345
Ensembl chr15:90,529,923...90,645,345
JBrowse link
G CRYZ crystallin zeta involved_in IPI (PMID:17497241) UniProt PMID:17497241 NCBI chr 1:74,705,486...74,733,050
Ensembl chr 1:74,705,482...74,733,408
JBrowse link
G CTH cystathionine gamma-lyase involved_in IPI (PMID:19019829) UniProt PMID:19019829 NCBI chr 1:70,411,268...70,439,851
Ensembl chr 1:70,411,218...70,439,851
JBrowse link
G DEFA5 defensin alpha 5 involved_in IDA (PMID:23163963) UniProt PMID:23163963 NCBI chr 8:7,055,304...7,056,739
Ensembl chr 8:7,055,304...7,056,739
JBrowse link
G DNM1 dynamin 1 involved_in IDA (PMID:9362482) UniProt PMID:9362482 NCBI chr 9:128,203,379...128,255,244
Ensembl chr 9:128,191,655...128,255,248
JBrowse link
G EVL Enah/Vasp-like involved_in IEA InterPro GO_REF:0000002 NCBI chr14:99,971,422...100,144,236
Ensembl chr14:99,971,449...100,144,236
JBrowse link
G GBP5 guanylate binding protein 5 involved_in IDA (PMID:22461501) UniProt PMID:22461501 NCBI chr 1:89,256,189...89,272,860
Ensembl chr 1:89,256,189...89,272,860
JBrowse link
G GLS glutaminase involved_in IEA
IDA
(PMID:22049910) Ensembl
UniProt
PMID:22049910 GO_REF:0000107 NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
JBrowse link
G GNMT glycine N-methyltransferase involved_in IPI
IBA
IEA
(PMID:15340920) UniProt
GO_Central
Ensembl
PMID:15340920 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:42,960,754...42,963,880
Ensembl chr 6:42,960,754...42,963,880
JBrowse link
G GOLGA2 golgin A2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:128,255,829...128,276,007
Ensembl chr 9:128,255,829...128,276,026
JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 involved_in IDA (PMID:17989220) UniProt PMID:17989220 NCBI chr  X:123,184,278...123,490,915
Ensembl chr  X:123,184,153...123,490,915
JBrowse link
G HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 involved_in IDA (PMID:28086084) UniProt PMID:28086084 NCBI chr 5:45,254,948...45,696,380
Ensembl chr 5:45,254,948...45,696,498
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 involved_in IPI (PMID:15990111) UniProt PMID:15990111 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513
JBrowse link
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 involved_in IDA (PMID:25925575) UniProt PMID:25925575 NCBI chr  X:53,431,258...53,434,376
Ensembl chr  X:53,431,258...53,434,370
JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506
JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 involved_in IDA (PMID:37898605) UniProt PMID:37898605 NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574
JBrowse link
G KCNJ12 potassium inwardly rectifying channel subfamily J member 12 involved_in IDA (PMID:21874019) UniProt PMID:21874019 NCBI chr17:21,376,357...21,419,870
Ensembl chr17:21,376,357...21,419,870
JBrowse link
G KCNJ2 potassium inwardly rectifying channel subfamily J member 2 involved_in IDA (PMID:20921230), (PMID:36149965) UniProt PMID:20921230 PMID:36149965 NCBI chr17:70,169,532...70,180,044
Ensembl chr17:70,168,673...70,180,044
JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 involved_in IDA (PMID:29724949) UniProt PMID:29724949 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976
JBrowse link
G KCNT1 potassium sodium-activated channel subfamily T member 1 involved_in IDA (PMID:37494189) UniProt PMID:37494189 NCBI chr 9:135,702,185...135,795,502
Ensembl chr 9:135,702,185...135,795,508
JBrowse link
G KIF25 kinesin family member 25 involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:167,997,671...168,045,091
Ensembl chr 6:167,996,241...168,045,091
JBrowse link
G MAT1A methionine adenosyltransferase 1A involved_in IDA (PMID:23425511) UniProt PMID:23425511 NCBI chr10:80,271,820...80,289,658
Ensembl chr10:80,271,820...80,289,658
JBrowse link
G MCOLN1 mucolipin TRP cation channel 1 involved_in IEA
IDA
(PMID:29019983) Ensembl
UniProt
PMID:29019983 GO_REF:0000107 NCBI chr19:7,522,624...7,534,009
Ensembl chr19:7,522,624...7,534,009
JBrowse link
G ME1 malic enzyme 1 involved_in IDA (PMID:7757881) UniProt PMID:7757881 NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051
JBrowse link
G OSBPL2 oxysterol binding protein like 2 involved_in IDA (PMID:30581148) UniProt PMID:30581148 NCBI chr20:62,238,521...62,296,183
Ensembl chr20:62,231,922...62,296,213
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel involved_in IDA (PMID:28092368) UniProt PMID:28092368 NCBI chr 4:88,007,635...88,077,777
Ensembl chr 4:88,007,635...88,077,777
JBrowse link
G PKD2L1 polycystin 2 like 1, transient receptor potential cation channel involved_in IDA (PMID:30004384) UniProt PMID:30004384 NCBI chr10:100,288,149...100,330,228
Ensembl chr10:100,288,149...100,330,264
JBrowse link
G PKM pyruvate kinase M1/2 ISO RGD PMID:10734049 RGD:151708737 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819
JBrowse link
G RYR1 ryanodine receptor 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273
JBrowse link
G RYR3 ryanodine receptor 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr15:33,310,967...33,866,102
Ensembl chr15:33,310,962...33,866,121
JBrowse link
G SAMHD1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in IEA
IDA
(PMID:23601106), (PMID:24217394), (PMID:26294762) Ensembl
UniProt
PMID:23601106 PMID:24217394 PMID:26294762 GO_REF:0000107 NCBI chr20:36,889,773...36,951,708
Ensembl chr20:36,890,229...36,951,893
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in IDA (PMID:24698160) UniProt PMID:24698160 NCBI chr17:18,327,873...18,363,550
Ensembl chr17:18,327,873...18,363,550
JBrowse link
G SHMT2 serine hydroxymethyltransferase 2 involved_in IDA (PMID:29180469) UniProt PMID:29180469 NCBI chr12:57,229,711...57,234,935
Ensembl chr12:57,229,573...57,234,935
JBrowse link
G SOD2 superoxide dismutase 2 involved_in IPI (PMID:19265433) UniProt PMID:19265433 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SSBP1 single stranded DNA binding protein 1 involved_in IDA (PMID:31550240) UniProt PMID:31550240 NCBI chr 7:141,738,321...141,750,488
Ensembl chr 7:141,738,334...141,787,922
JBrowse link
G SYCP1 synaptonemal complex protein 1 involved_in IDA (PMID:29915389) UniProt PMID:29915389 NCBI chr 1:114,854,088...114,995,370
Ensembl chr 1:114,854,863...114,995,370
JBrowse link
G TDO2 tryptophan 2,3-dioxygenase involved_in IDA (PMID:27762317), (PMID:28285122) UniProt PMID:27762317 PMID:28285122 NCBI chr 4:155,903,696...155,920,406
Ensembl chr 4:155,854,738...155,920,406
JBrowse link
G THG1L tRNA-histidine guanylyltransferase 1 like involved_in IPI (PMID:21059936) UniProt PMID:21059936 NCBI chr 5:157,731,420...157,741,449
Ensembl chr 5:157,731,420...157,741,449
JBrowse link
G TK1 thymidine kinase 1 involved_in IPI
IDA
(PMID:17407781)
(PMID:14697231)
UniProt PMID:14697231 PMID:17407781 NCBI chr17:78,174,079...78,187,204
Ensembl chr17:78,174,091...78,187,233
JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 involved_in IDA (PMID:25855297) UniProt PMID:25855297 NCBI chr 8:72,021,250...72,090,010
Ensembl chr 8:72,019,917...72,075,584
JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 involved_in IDA (PMID:30467180) UniProt PMID:30467180 NCBI chr21:44,353,621...44,442,644
Ensembl chr21:44,350,163...44,443,081
JBrowse link
G TRPM3 transient receptor potential cation channel subfamily M member 3 involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:70,529,060...71,446,971
Ensembl chr 9:70,529,060...71,446,977
JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IDA
IEA
(PMID:29211723), (PMID:29217581) UniProt
Ensembl
PMID:29211723 PMID:29217581 GO_REF:0000107 NCBI chr19:49,157,792...49,211,836
Ensembl chr19:49,157,741...49,211,836
JBrowse link
G TRPM7 transient receptor potential cation channel subfamily M member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:50,557,158...50,686,797
Ensembl chr15:50,552,473...50,686,797
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
JBrowse link
G TRPV5 transient receptor potential cation channel subfamily V member 5 involved_in ISS UniProt GO_REF:0000024 NCBI chr 7:142,908,101...142,933,746
Ensembl chr 7:142,908,101...142,933,746
JBrowse link
G TRPV6 transient receptor potential cation channel subfamily V member 6 involved_in ISO PMID:27296226 UniProt PMID:27296226 RGD:11344952 NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745
JBrowse link
G UPB1 beta-ureidopropionase 1 involved_in IDA (PMID:29976570) UniProt PMID:29976570 NCBI chr22:24,495,332...24,528,390
Ensembl chr22:24,494,107...24,528,390
JBrowse link
G USP16 ubiquitin specific peptidase 16 involved_in IEA
IPI
(PMID:17914355) UniProt PMID:17914355 GO_REF:0000104 NCBI chr21:29,024,668...29,054,488
Ensembl chr21:29,024,629...29,054,488
JBrowse link
G VASP vasodilator stimulated phosphoprotein involved_in IEA InterPro GO_REF:0000002 NCBI chr19:45,507,479...45,526,983
Ensembl chr19:45,506,579...45,526,989
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20484
    cellular process 19726
      cellular component organization or biogenesis 7903
        cellular component organization 7673
          cellular component assembly 3750
            protein-containing complex assembly 2086
              protein complex oligomerization 293
                protein homooligomerization 221
                  protein homotetramerization 68
                    negative regulation of protein homotetramerization 0
                    positive regulation of protein homotetramerization 0
                    regulation of protein homotetramerization + 0
paths to the root