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ONTOLOGY REPORT - ANNOTATIONS

Term:protein homotetramerization
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Accession:GO:0051289 term browser browse the term
Definition:The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
Synonyms:exact_synonym: protein homotetramer assembly;   protein homotetramer biosynthesis;   protein homotetramer biosynthetic process;   protein homotetramer formation


show annotations for term's descendants           Sort by:
protein homotetramerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:20952656)		 UniProt
Ensembl
RGD		 PMID:20952656 GO_REF:0000024 GO_REF:0000107 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta involved_in ISO (PMID:20952656) RGD PMID:20952656 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 involved_in ISO UniProtKB:Q9NPJ3 (PMID:16934754), (PMID:19170545) RGD PMID:16934754 PMID:19170545 NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 involved_in ISO
ISS		 (PMID:29240402)
GO_REF:0000024		 RGD
UniProt		 PMID:29240402 GO_REF:0000024 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 involved_in ISO
ISS
IEA		 (PMID:27759097)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:27759097 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family, member A1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:30914451)		 UniProt
RGD		 PMID:30914451 GO_REF:0000024 NCBI chr13:79,505,738...79,522,539
Ensembl chr13:79,505,695...79,540,568 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Apip APAF1 interacting protein involved_in ISO (PMID:24367089) RGD PMID:24367089 NCBI chr 3:89,431,964...89,458,000
Ensembl chr 3:89,432,037...89,458,340 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:23055524) RGD PMID:23055524 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754 		JBrowse link
G Aqp10 aquaporin 10 involved_in ISO (PMID:30420639) RGD PMID:30420639 NCBI chr 2:175,402,609...175,407,677
Ensembl chr 2:175,403,263...175,406,815 		JBrowse link
G Aqp2 aquaporin 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24733887)		 UniProt
Ensembl
RGD		 PMID:24733887 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468 		JBrowse link
G Aqp4 aquaporin 4 involved_in IDA
ISO
IEA		 PMID:16325200
(PMID:19383790)
GO_REF:0000107		 RGD
Ensembl		 PMID:19383790 PMID:16325200 GO_REF:0000107, RGD:14397562 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Aqp5 aquaporin 5 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:18768791), (PMID:26569106)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18768791 PMID:26569106 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209 		JBrowse link
G B2m beta-2 microglobulin involved_in ISO
IEA		 UniProtKB:P61769 (PMID:28468825)
GO_REF:0000107		 RGD
Ensembl		 PMID:28468825 GO_REF:0000107 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766 		JBrowse link
G Cbr4 carbonyl reductase 4 involved_in ISO
IEA		 (PMID:19000905)
GO_REF:0000107		 RGD
Ensembl		 PMID:19000905 GO_REF:0000107 NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712 		JBrowse link
G Cby1 chibby 1, beta catenin antagonist involved_in ISO (PMID:21182262) RGD PMID:21182262 NCBI chr 7:111,216,835...111,223,305 JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:18,988,197...19,046,914
Ensembl chr16:18,988,250...19,043,381 		JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:175,709,603...175,719,768
Ensembl chr 2:175,709,644...175,719,763 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500 		JBrowse link
G Cryz crystallin zeta involved_in ISO
IEA		 UniProtKB:Q08257 (PMID:17497241)
GO_REF:0000107		 RGD
Ensembl		 PMID:17497241 GO_REF:0000107 NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758 		JBrowse link
G Cth cystathionine gamma-lyase involved_in ISO
IEA		 UniProtKB:P32929 (PMID:19019829)
GO_REF:0000107		 RGD
Ensembl		 PMID:19019829 GO_REF:0000107 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Defa5 defensin alpha 5 involved_in ISO (PMID:23163963) RGD PMID:23163963 NCBI chr16:70,342,530...70,344,854
Ensembl chr16:70,342,530...70,344,836 		JBrowse link
G Dnm1 dynamin 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:9362482)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9362482 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:15,604,782...15,648,654
Ensembl chr 3:15,604,784...15,648,538 		JBrowse link
G Evl Enah/Vasp-like involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:127,473,119...127,594,342
Ensembl chr 6:127,474,543...127,594,344 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) RGD PMID:22461501 NCBI chr 2:231,237,748...231,257,071
Ensembl chr 2:231,237,748...231,257,061 		JBrowse link
G Gls glutaminase involved_in ISO
ISS
IEA		 (PMID:22049910)
GO_REF:0000024
GO_REF:0000107
(PMID:22228304)		 RGD
UniProt
Ensembl		 PMID:22049910 PMID:22228304 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900 		JBrowse link
G Gnmt glycine N-methyltransferase involved_in ISO
IPI
IEA
IBA		 UniProtKB:Q14749 (PMID:15340920)
GO_REF:0000107
GO_REF:0000033
UniProtKB:Q9QXF8 (PMID:15340920)		 RGD
Ensembl
GO_Central		 PMID:15340920 PMID:15340920 GO_REF:0000033 GO_REF:0000107, RGD:8553948 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434 		JBrowse link
G Golga2 golgin A2 involved_in IDA PMID:25787021 UniProt PMID:25787021 RGD:10400873 NCBI chr 3:15,583,862...15,604,279
Ensembl chr 3:15,584,039...15,604,279 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 involved_in ISO
ISS
IEA		 (PMID:17989220)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:17989220 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:28086084)		 UniProt
RGD		 PMID:28086084 GO_REF:0000024 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO
IEA		 UniProtKB:P00492 (PMID:15990111)
GO_REF:0000107		 RGD
Ensembl		 PMID:15990111 GO_REF:0000107 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 involved_in ISO
IEA		 (PMID:25925575)
GO_REF:0000107		 RGD
Ensembl		 PMID:25925575 GO_REF:0000107 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 involved_in ISS
IDA
IEA
ISO		 GO_REF:0000024
PMID:36376291
GO_REF:0000107
(PMID:35568199)		 UniProt
Ensembl
RGD		 PMID:35568199 PMID:36376291 GO_REF:0000024 GO_REF:0000107, RGD:405650379 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 involved_in ISO
ISS
IEA		 (PMID:37898605)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:37898605 GO_REF:0000024 GO_REF:0000107 NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337 		JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 involved_in ISO
ISS		 (PMID:21874019)
GO_REF:0000024		 RGD
UniProt		 PMID:21874019 GO_REF:0000024 NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20921230), (PMID:36149965)		 UniProt
RGD		 PMID:20921230 PMID:36149965 GO_REF:0000024 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in ISO
IEA		 (PMID:29724949)
GO_REF:0000107		 RGD
Ensembl		 PMID:29724949 GO_REF:0000107 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Kcnt1 potassium sodium-activated channel subfamily T member 1 involved_in ISO
ISS		 (PMID:37494189)
GO_REF:0000024		 RGD
UniProt		 PMID:37494189 GO_REF:0000024 NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667 		JBrowse link
G Mat1a methionine adenosyltransferase 1A involved_in ISO (PMID:23425511) RGD PMID:23425511 NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274 		JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in ISO (PMID:29019983)
(PMID:29019981)		 RGD PMID:29019981 PMID:29019983 NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252 		JBrowse link
G Me1 malic enzyme 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:7757881)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:7757881 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Osbpl2 oxysterol binding protein-like 2 involved_in ISO (PMID:30581148) RGD PMID:30581148 NCBI chr 3:167,210,945...167,256,219
Ensembl chr 3:167,210,832...167,256,219 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:28092368) RGD PMID:28092368 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO (PMID:30004384) RGD PMID:30004384 NCBI chr 1:243,032,891...243,070,031
Ensembl chr 1:243,032,913...243,070,031 		JBrowse link
G Pkm pyruvate kinase M1/2 IDA RGD PMID:10734049 RGD:151708737 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Ryr1 ryanodine receptor 1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (PMID:23601106), (PMID:24217394), (PMID:26294762)
(PMID:29379009)		 RGD PMID:23601106 PMID:24217394 PMID:26294762 PMID:29379009 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:24698160) RGD PMID:24698160 NCBI chr10:45,468,698...45,490,833
Ensembl chr10:45,468,700...45,497,820 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in ISO (PMID:29180469) RGD PMID:29180469 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO UniProtKB:P04179 (PMID:19265433) RGD PMID:19265433 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:31550240)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:31550240 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135 		JBrowse link
G Sycp1 synaptonemal complex protein 1 involved_in ISO
IEA
ISS		 (PMID:29915389)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:29915389 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:190,296,688...190,456,687
Ensembl chr 2:190,296,954...190,456,737 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in ISO
ISS		 (PMID:27762317), (PMID:28285122)
GO_REF:0000024		 RGD
UniProt		 PMID:27762317 PMID:28285122 GO_REF:0000024 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511 		JBrowse link
G Thg1l tRNA-histidine guanylyltransferase 1-like involved_in ISO
IEA		 UniProtKB:Q9NWX6 (PMID:21059936)
GO_REF:0000107		 RGD
Ensembl		 PMID:21059936 GO_REF:0000107 NCBI chr10:30,387,929...30,396,579
Ensembl chr10:30,387,940...30,396,687 		JBrowse link
G Tk1 thymidine kinase 1 involved_in ISO
ISS		 UniProtKB:P04183 (PMID:14697231), (PMID:17407781)
GO_REF:0000024		 RGD
UniProt		 PMID:14697231 PMID:17407781 GO_REF:0000024 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 involved_in ISO
ISS		 (PMID:25855297)
GO_REF:0000024		 RGD
UniProt		 PMID:25855297 GO_REF:0000024 NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:30467180)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:30467180 GO_REF:0000024 GO_REF:0000107 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:29211723), (PMID:29217581)
GO_REF:0000107
(PMID:29211714)		 UniProt
RGD
Ensembl		 PMID:29211714 PMID:29211723 PMID:29217581 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 involved_in ISS
ISO		 GO_REF:0000024
(PMID:30108148)		 UniProt
RGD		 PMID:30108148 GO_REF:0000024 NCBI chr 3:114,046,258...114,134,799
Ensembl chr 3:114,046,258...114,135,190 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 involved_in IDA PMID:27281200 UniProt PMID:27281200 RGD:11344330 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745 		JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 involved_in IPI PMID:27296226 UniProt PMID:27296226 RGD:11344952 NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017 		JBrowse link
G Upb1 beta-ureidopropionase 1 involved_in ISO (PMID:29976570) RGD PMID:29976570 NCBI chr20:13,217,252...13,243,590
Ensembl chr20:13,217,258...13,243,590 		JBrowse link
G Usp16 ubiquitin specific peptidase 16 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q9Y5T5 (PMID:17914355)		 UniProt
RGD		 PMID:17914355 GO_REF:0000024 NCBI chr11:26,681,359...26,711,313
Ensembl chr11:26,681,414...26,710,539 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20537
    cellular process 19526
      cellular component organization or biogenesis 7187
        cellular component organization 6903
          cellular component assembly 3197
            protein-containing complex assembly 1601
              protein complex oligomerization 286
                protein homooligomerization 213
                  protein homotetramerization 65
                    negative regulation of protein homotetramerization 0
                    positive regulation of protein homotetramerization 0
                    regulation of protein homotetramerization + 0
paths to the root