ONTOLOGY REPORT - ANNOTATIONS
Term: detection of mechanical stimulus involved in sensory perception of pain
Accession: GO:0050966
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Definition: The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.
Synonyms: exact_synonym: perception of pain, detection of mechanical stimulus; perception of pain, sensory detection of mechanical stimulus; perception of pain, sensory transduction of mechanical stimulus; sensory detection of mechanical stimulus during perception of pain; sensory transduction of mechanical stimulus during perception of pain
related_synonym: mechanical nociception
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Ano1
anoctamin 1
NOT|involved_in
ISO
(PMID:22634729)
RGD
PMID:22634729
NCBI chr 1:209,180,755...209,329,413
Ensembl chr 1:199,751,439...199,900,069
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Asic3
acid sensing ion channel subunit 3
acts_upstream_of_or_within
ISO
MGI:2429689|MGI:2451051 (PMID:11754838), (PMID:12060708)
RGD
PMID:11754838 PMID:12060708
NCBI chr 4:11,652,946...11,657,415
Ensembl chr 4:10,760,597...10,764,643
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Bace1
beta-secretase 1
IMP
RGD
PMID:28012171
RGD:13782150
NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:46,142,116...46,165,876
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Cacnb3
calcium voltage-gated channel auxiliary subunit beta 3
IMP
RGD
PMID:22187436
RGD:13514092
NCBI chr 7:131,663,810...131,676,085
Ensembl chr 7:129,783,674...129,797,074
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Chrna5
cholinergic receptor nicotinic alpha 5 subunit
IMP
RGD
PMID:15652389
RGD:150530460
NCBI chr 8:64,265,879...64,294,233
Ensembl chr 8:55,369,794...55,398,146
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Cxcl12
C-X-C motif chemokine ligand 12
IMP
RGD
PMID:27760212
RGD:12910551
NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168
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Cxcr4
C-X-C motif chemokine receptor 4
IMP
RGD
PMID:27760212 PMID:28108674
RGD:12910551 , RGD:13463594
NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883
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Fyn
FYN proto-oncogene, Src family tyrosine kinase
acts_upstream_of_or_within
ISO IEA
MGI:1930480 (PMID:16190898) GO_REF:0000107
RGD Ensembl
PMID:16190898
GO_REF:0000107
NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
NOT|acts_upstream_of_or_within
ISO
MGI:1928285 (PMID:16190898)
RGD
PMID:16190898
NCBI chr10:6,136,458...6,560,003
Ensembl chr10:5,631,369...6,044,637
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
acts_upstream_of_or_within
ISO
(PMID:16190898)
RGD
PMID:16190898
NCBI chr 4:170,297,811...170,775,420
Ensembl chr 4:168,599,546...169,042,279
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Grin2d
glutamate ionotropic receptor NMDA type subunit 2D
NOT|acts_upstream_of_or_within
ISO
MGI:1928298 (PMID:16190898)
RGD
PMID:16190898
NCBI chr 1:105,443,317...105,483,400
Ensembl chr 1:96,308,365...96,344,793
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Grm8
glutamate metabotropic receptor 8
IDA
RGD
PMID:18533199
RGD:6771181
NCBI chr 4:56,771,247...57,696,951
Ensembl chr 4:55,805,955...56,730,831
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Htr2a
5-hydroxytryptamine receptor 2A
IMP
RGD
PMID:20531396
RGD:7257680
NCBI chr15:56,360,647...56,428,703
Ensembl chr15:49,950,804...50,020,928
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Htr7
5-hydroxytryptamine receptor 7
IDA
RGD
PMID:21843960
RGD:6482179
NCBI chr 1:243,049,064...243,173,636
Ensembl chr 1:233,636,452...233,760,626
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Il18
interleukin 18
IDA
RGD
PMID:19853379
RGD:2315887
NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887
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Itga2
integrin subunit alpha 2
IMP
RGD
PMID:18234883
RGD:2303705
NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:46,523,948...46,621,481
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Kcna1
potassium voltage-gated channel subfamily A member 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:23473320)
UniProt RGD
PMID:23473320
GO_REF:0000024
NCBI chr 4:161,150,378...161,160,051
Ensembl chr 4:159,464,188...159,472,682
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Mir15b
microRNA 15b
IDA
RGD
PMID:28012171
RGD:13782150
NCBI chr 2:155,555,178...155,555,275
Ensembl chr 2:153,245,200...153,245,297
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Mir338
microRNA 338
IMP
RGD
PMID:28108674
RGD:13463594
NCBI chr10:105,796,342...105,796,407
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Ntrk1
neurotrophic receptor tyrosine kinase 1
IMP
RGD
PMID:20351485
RGD:5684352
NCBI chr 2:175,534,844...175,551,664
Ensembl chr 2:173,236,963...173,253,770
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Pawr
pro-apoptotic WT1 regulator
IDA
RGD
PMID:21238854
RGD:9835398
NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:43,645,084...43,725,028
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Phf24
PHD finger protein 24
acts_upstream_of_or_within
ISO IEA
MGI:5706936 (PMID:25242222) GO_REF:0000107
RGD Ensembl
PMID:25242222
GO_REF:0000107
NCBI chr 5:61,939,261...61,966,879
Ensembl chr 5:57,142,632...57,168,497
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Scn11a
sodium voltage-gated channel alpha subunit 11
involved_in
IEA ISO
GO_REF:0000107 MGI:5608917 (PMID:31534133)
Ensembl RGD
PMID:31534133
GO_REF:0000107
NCBI chr 8:128,374,441...128,444,718
Ensembl chr 8:119,496,769...119,567,044
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Scn1a
sodium voltage-gated channel alpha subunit 1
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:27281198)
UniProt Ensembl RGD
PMID:27281198
GO_REF:0000024 GO_REF:0000107
NCBI chr 3:71,360,840...71,479,870
Ensembl chr 3:50,952,791...51,071,699
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Tlr4
toll-like receptor 4
IMP
RGD
PMID:27760212
RGD:12910551
NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
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Tmem120a
transmembrane protein 120A
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:32084332) GO_REF:0000107
UniProt RGD Ensembl
PMID:32084332
GO_REF:0000024 GO_REF:0000107
NCBI chr12:26,578,859...26,587,524
Ensembl chr12:20,942,439...20,990,316
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Tnf
tumor necrosis factor
IMP
RGD
PMID:16675114
RGD:7387300
NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
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Trpa1
transient receptor potential cation channel, subfamily A, member 1
acts_upstream_of_or_within
ISO IEA
MGI:3624810 (PMID:16630838) GO_REF:0000107
RGD Ensembl
PMID:16630838
GO_REF:0000107
NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:4,379,999...4,433,570
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