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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of B cell activation
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Accession:GO:0050871 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of B cell activation.
Synonyms:exact_synonym: positive regulation of B lymphocyte activation;   up regulation of B cell activation;   upregulation of B cell activation
 narrow_synonym: activation of B cell activation;   stimulation of B cell activation



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positive regulation of B cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akirin2 akirin 2 involved_in ISO (PMID:26041538) RGD PMID:26041538 NCBI chr 5:53,897,792...53,918,873
Ensembl chr 5:49,108,220...49,122,568
JBrowse link
G Cd81 Cd81 molecule involved_in ISS
ISO
GO_REF:0000024
(PMID:23499492)
UniProt
RGD
PMID:23499492 GO_REF:0000024 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:16129705), (PMID:8566034), (PMID:9798653) RGD PMID:8566034 PMID:9798653 PMID:16129705 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:3491322) RGD PMID:3491322 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO (PMID:20844241) RGD PMID:20844241 NCBI chr19:34,555,832...34,596,281
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (PMID:19734906) RGD PMID:19734906 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285
JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:29636373)
Ensembl
RGD
PMID:29636373 GO_REF:0000107 NCBI chr  X:38,686,530...39,031,658
Ensembl chr  X:34,877,866...35,222,747
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:3029019 (PMID:12855817) RGD PMID:12855817 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:23857366) RGD PMID:23857366 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:9670042) RGD PMID:9670042 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in ISO (PMID:16633345) RGD PMID:16633345 NCBI chr14:80,452,936...80,470,141
Ensembl chr14:76,228,371...76,275,265
JBrowse link
B cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd320 CD320 molecule involved_in ISO
ISS
(PMID:10727470)
GO_REF:0000024
RGD
UniProt
PMID:10727470 GO_REF:0000024 NCBI chr 7:14,626,171...14,631,976
Ensembl chr 7:14,609,146...14,631,976
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18762567) RGD PMID:18762567 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:15240667)
GO_Central
RGD
PMID:15240667 GO_REF:0000033 NCBI chr 7:113,736,046...113,738,523
Ensembl chr 7:113,736,055...113,738,517
JBrowse link
G Tnfsf13b TNF superfamily member 13b acts_upstream_of_or_within ISO (PMID:15240667) RGD PMID:15240667 NCBI chr16:86,164,377...86,195,072
Ensembl chr16:79,462,402...79,492,693
JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase phospholipid transporting 11C involved_in ISO (PMID:21423173) RGD PMID:21423173 NCBI chr  X:143,600,763...143,788,407
Ensembl chr  X:138,565,836...138,751,204
JBrowse link
G Bad BCL2-associated agonist of cell death involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3029528 (PMID:12431371)
Ensembl
RGD
PMID:12431371 GO_REF:0000107 NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Cd27 CD27 molecule involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:158,030,700...158,035,862
Ensembl chr 4:158,030,703...158,035,592
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma acts_upstream_of_or_within ISO MGI:2429736|MGI:5544783 (PMID:23918385), (PMID:9252128) RGD PMID:9252128 PMID:23918385 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823
JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:16797412)
Ensembl
RGD
PMID:16797412 GO_REF:0000107 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:2386884 (PMID:10704460), (PMID:9620849)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:9620849 PMID:10704460 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:95,735,533...95,840,584
Ensembl chr 9:88,287,677...88,392,746
JBrowse link
G Mmp14 matrix metallopeptidase 14 involved_in ISS
ISO
GO_REF:0000024
(PMID:21572390)
UniProt
RGD
PMID:21572390 GO_REF:0000024 NCBI chr15:31,857,824...31,867,049
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISS
ISO
GO_REF:0000024
(PMID:19015308)
UniProt
RGD
PMID:19015308 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
G Pcid2 PCI domain containing 2 involved_in ISO (PMID:20870947) RGD PMID:20870947 NCBI chr16:76,423,245...76,448,712
Ensembl chr16:76,423,245...76,448,712
JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:3759678 (PMID:16129705)
GO_REF:0000033
Ensembl
RGD
GO_Central
PMID:16129705 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:78,382,849...78,406,037
Ensembl chr 6:72,647,025...72,672,491
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO
IEA
ISS
(PMID:33951726)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:33951726 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:77,073,012...77,092,393
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035 (PMID:10979977) RGD PMID:10979977 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:103036 (PMID:10979977)
Ensembl
RGD
PMID:10979977 GO_REF:0000107 NCBI chr10:86,205,148...86,276,178
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Syk spleen associated tyrosine kinase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857421|MGI:2384078 (PMID:7477352), (PMID:7477353)
(PMID:18369315)
Ensembl
RGD
PMID:7477352 PMID:7477353 PMID:18369315 GO_REF:0000107 NCBI chr17:12,756,493...12,830,927
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
ISS
(PMID:11460154)
GO_REF:0000024
RGD
UniProt
PMID:11460154 GO_REF:0000024 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693
JBrowse link
positive regulation of B cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857117|MGI:2683027 (PMID:14607964)
Ensembl
RGD
PMID:14607964 GO_REF:0000107 NCBI chr 3:172,818,174...172,842,283
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:4127920 (PMID:25404367) RGD PMID:25404367 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Bcl2 BCL2, apoptosis regulator involved_in ISO
IEA
(PMID:17875758)
GO_REF:0000107
RGD
Ensembl
PMID:17875758 GO_REF:0000107 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158437 (PMID:9171827) RGD PMID:9171827 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger involved_in ISO (PMID:15964995) RGD PMID:15964995 NCBI chr17:86,240,683...86,250,044
Ensembl chr17:81,332,214...81,388,690
JBrowse link
G Bst1 bone marrow stromal cell antigen 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr14:71,466,179...71,482,671
Ensembl chr14:67,252,998...67,270,180
JBrowse link
G Btk Bruton tyrosine kinase IMP RGD PMID:28352114 RGD:151665126 NCBI chr  X:102,016,070...102,055,448
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G Card11 caspase recruitment domain family, member 11 acts_upstream_of_or_within ISO MGI:3039682 (PMID:12867038) RGD PMID:12867038 NCBI chr12:13,621,140...13,758,115
Ensembl chr12:13,621,087...13,758,112
JBrowse link
G Cd320 CD320 molecule involved_in ISO
ISS
(PMID:10727470)
GO_REF:0000024
RGD
UniProt
PMID:10727470 GO_REF:0000024 NCBI chr 7:14,626,171...14,631,976
Ensembl chr 7:14,609,146...14,631,976
JBrowse link
G Cd38 CD38 molecule involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17875758)
(PMID:8666928)
GO_REF:0000033
RGD
GO_Central
PMID:8666928 PMID:17875758 GO_REF:0000033 NCBI chr14:71,384,532...71,424,794
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO MGI:87891 (PMID:10979977), (PMID:11894097), (PMID:14607964), (PMID:15963492), (PMID:8666928), (PMID:8920854) RGD PMID:8666928 PMID:8920854 PMID:10979977 PMID:11894097 PMID:14607964 More... NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Cd40lg CD40 ligand IDA RGD PMID:18384807 RGD:2313415 NCBI chr  X:140,164,341...140,176,057
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Cd74 CD74 molecule involved_in ISO
IEA
(PMID:12782713)
GO_REF:0000107
RGD
Ensembl
PMID:12782713 GO_REF:0000107 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd81 Cd81 molecule involved_in ISO
IEA
(PMID:10400713)
GO_REF:0000107
RGD
Ensembl
PMID:10400713 GO_REF:0000107 NCBI chr 1:207,665,274...207,681,094
Ensembl chr 1:198,241,484...198,251,660
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A acts_upstream_of_or_within ISO MGI:107739 (PMID:12970760) RGD PMID:12970760 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:88336 (PMID:15963492) RGD PMID:15963492 NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in IBA
ISO
GO_REF:0000033
(PMID:12023368)
GO_Central
RGD
PMID:12023368 GO_REF:0000033 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:201,507,859...201,517,605
JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO (PMID:24803541) RGD PMID:24803541 NCBI chr 5:154,179,065...154,360,459
Ensembl chr 5:148,897,246...149,077,059
JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in ISS
ISO
GO_REF:0000024
(PMID:21673108)
UniProt
RGD
PMID:21673108 GO_REF:0000024 NCBI chr15:105,445,129...105,457,192
Ensembl chr15:99,036,367...99,050,559
JBrowse link
G Il13 interleukin 13 IDA requires CD40 antigen RGD PMID:11573960 PMID:10331006 RGD:633067, RGD:61509 NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 IDA requires CD40 antigen RGD PMID:11573960 RGD:633067 NCBI chr  X:120,213,670...120,294,777
Ensembl chr  X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:9184696) RGD PMID:9184696 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:17673207)
GO_REF:0000107
RGD
Ensembl
PMID:17673207 GO_REF:0000107 NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within ISO (PMID:7736574) RGD PMID:7736574 NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:10979977), (PMID:14607964) RGD PMID:10979977 PMID:14607964 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il5 interleukin 5 IDA RGD PMID:10529595 RGD:2303750 NCBI chr10:38,375,132...38,378,003
Ensembl chr10:37,874,342...37,877,213
JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within
ISS
ISO
IEA
GO_REF:0000024
MGI:87859 (PMID:12970760), (PMID:7671324)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:7671324 PMID:12970760 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:96,142,523...96,186,282
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Irs2 insulin receptor substrate 2 involved_in ISO (PMID:15572028) RGD PMID:15572028 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO
GO_REF:0000024
(PMID:18955699)
UniProt
RGD
PMID:18955699 GO_REF:0000024 NCBI chr 2:15,708,732...15,871,639
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (PMID:12782713) RGD PMID:12782713 NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504
JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO
ISS
(PMID:17875758)
GO_REF:0000024
RGD
UniProt
PMID:17875758 GO_REF:0000024 NCBI chr 7:136,455,900...136,501,384
Ensembl chr 7:134,577,482...134,622,934
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:157,198,872...157,328,325
JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (PMID:19734906) RGD PMID:19734906 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285
JBrowse link
G Prlr prolactin receptor IMP RGD PMID:8650199 PMID:9447986 RGD:151665811, RGD:151667430 NCBI chr 2:60,861,391...61,051,883
Ensembl chr 2:59,134,588...59,324,718
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in
acts_upstream_of_or_within
ISO (PMID:1793833)
MGI:1857277|MGI:2181288 (PMID:8566034), (PMID:8666928), (PMID:9015183), (PMID:9254656)
RGD PMID:1793833 PMID:8566034 PMID:8666928 PMID:9015183 PMID:9254656 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Sash3 SAM and SH3 domain containing 3 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3716944 (PMID:16227612)
GO_REF:0000033
RGD
GO_Central
PMID:16227612 GO_REF:0000033 NCBI chr  X:132,204,717...132,219,421
Ensembl chr  X:127,326,859...127,341,519
JBrowse link
G Slc39a10 solute carrier family 39 member 10 acts_upstream_of_or_within ISO MGI:5642299 (PMID:25074919) RGD PMID:25074919 NCBI chr 9:62,331,281...62,454,754
Ensembl chr 9:54,876,141...54,960,325
JBrowse link
G Tcf3 transcription factor 3 involved_in ISO
ISS
(PMID:11509675)
GO_REF:0000024
RGD
UniProt
PMID:11509675 GO_REF:0000024 NCBI chr 7:9,931,251...9,952,994
Ensembl chr 7:9,280,571...9,302,314
JBrowse link
G Tfrc transferrin receptor involved_in ISS
ISO
GO_REF:0000024
(PMID:26642240)
UniProt
RGD
PMID:26642240 GO_REF:0000024 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within ISO MGI:3029019 (PMID:12855817) RGD PMID:12855817 NCBI chr 9:1,189,717...1,197,730
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tirap TIR domain containing adaptor protein involved_in ISO (PMID:12447442) RGD PMID:12447442 NCBI chr 8:41,789,557...41,805,903
Ensembl chr 8:33,531,725...33,547,432
JBrowse link
G Tlr4 toll-like receptor 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1860885 (PMID:10549626)
Ensembl
RGD
PMID:10549626 GO_REF:0000107 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO (PMID:23857366) RGD PMID:23857366 NCBI chr 8:115,743,407...115,747,523
Ensembl chr 8:106,864,680...106,868,796
JBrowse link
G Tnfrsf13c TNF receptor superfamily member 13C involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
(PMID:15240667)
GO_Central
RGD
PMID:15240667 GO_REF:0000033 NCBI chr 7:113,736,046...113,738,523
Ensembl chr 7:113,736,055...113,738,517
JBrowse link
G Tnfrsf4 TNF receptor superfamily member 4 involved_in ISO (PMID:7749983) RGD PMID:7749983 NCBI chr 5:171,889,134...171,891,824
Ensembl chr 5:166,606,909...166,609,599
JBrowse link
G Tnfsf13 TNF superfamily member 13 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,400,065...54,403,042
JBrowse link
G Tnfsf13b TNF superfamily member 13b involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:17499850)
(PMID:15240667)
GO_REF:0000033
RGD
GO_Central
PMID:15240667 PMID:17499850 GO_REF:0000033 NCBI chr16:86,164,377...86,195,072
Ensembl chr16:79,462,402...79,492,693
JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 involved_in ISO (PMID:17875758) RGD PMID:17875758 NCBI chr 2:199,699,861...200,042,344
Ensembl chr 2:197,011,831...197,354,321
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO (PMID:10933391) RGD PMID:10933391 NCBI chr10:44,533,734...44,577,919
Ensembl chr10:44,034,194...44,078,324
JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 TNF superfamily member 4 involved_in ISO (PMID:12496423) RGD PMID:12496423 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788
JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within ISO (PMID:21255825) RGD PMID:21255825 NCBI chr 5:64,369,495...64,374,711
Ensembl chr 5:59,573,886...59,579,060
JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within ISO (PMID:21255825) RGD PMID:21255825 NCBI chr19:55,931,523...55,932,937
Ensembl chr19:39,022,183...39,023,515
JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific involved_in ISS
ISO
GO_REF:0000024
(PMID:31806351)
UniProt
RGD
PMID:31806351 GO_REF:0000024 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616
JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in ISS
ISO
GO_REF:0000024
(PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024 NCBI chr 1:210,429,672...210,479,042
Ensembl chr 1:201,000,444...201,049,819
JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in ISS
ISO
GO_REF:0000024
(PMID:28114273)
UniProt
RGD
PMID:28114273 GO_REF:0000024 NCBI chr 1:69,099,531...69,107,145
Ensembl chr 1:69,099,539...69,107,145
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr 5:163,846,678...163,859,851
Ensembl chr 5:158,563,567...158,576,693
JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:20671152) RGD PMID:20671152 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548
JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in ISO (PMID:23306439), (PMID:23333305), (PMID:23333306) RGD PMID:23306439 PMID:23333305 PMID:23333306 NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA
(PMID:29656893)
GO_REF:0000033
RGD
GO_Central
PMID:29656893 GO_REF:0000033 NCBI chr 3:140,391,611...140,462,273
Ensembl chr 3:119,938,833...120,009,550
JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO (PMID:29656893) RGD PMID:29656893 NCBI chr16:9,554,921...9,646,186
Ensembl chr16:9,548,660...9,639,965
JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO
IBA
(PMID:29656893)
GO_REF:0000033
RGD
GO_Central
PMID:29656893 GO_REF:0000033 NCBI chr 2:35,297,255...35,302,071
Ensembl chr 2:35,295,859...35,302,346
JBrowse link
G Tfrc transferrin receptor involved_in ISS
ISO
GO_REF:0000024
(PMID:26642240)
UniProt
RGD
PMID:26642240 GO_REF:0000024 NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257
JBrowse link
G Tp53bp1 tumor protein p53 binding protein 1 involved_in ISO (PMID:23345425), (PMID:23760478)
(PMID:15077110), (PMID:15159415)
RGD PMID:15077110 PMID:15159415 PMID:23345425 PMID:23760478 NCBI chr 3:128,620,320...128,724,716
Ensembl chr 3:108,169,980...108,269,822
JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within ISO (PMID:23241889) RGD PMID:23241889 NCBI chr14:81,057,727...81,135,866
Ensembl chr14:76,835,637...76,913,641
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (PMID:10430621) RGD PMID:10430621 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(PMID:14988498)
AgBase
RGD
PMID:14988498 GO_REF:0000024 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnfsf13 TNF superfamily member 13 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:14988498)
MGI:3038886 (PMID:14988498)
GO_REF:0000033
RGD
GO_Central
PMID:14988498 GO_REF:0000033 NCBI chr10:54,898,805...54,901,815
Ensembl chr10:54,400,065...54,403,042
JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in ISO (PMID:12023368) RGD PMID:12023368 NCBI chr 1:210,937,763...210,947,064
Ensembl chr 1:201,507,859...201,517,605
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:14988498) RGD PMID:14988498 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within ISO MGI:107187 (PMID:10490661) RGD PMID:10490661 NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within ISO MGI:4127920 (PMID:25404367) RGD PMID:25404367 NCBI chr10:65,568,569...65,616,379
Ensembl chr10:65,070,689...65,117,845
JBrowse link
G Cd28 Cd28 molecule acts_upstream_of_or_within ISO MGI:1857150 (PMID:7688139) RGD PMID:7688139 NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685
JBrowse link
G Cd40 CD40 molecule acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534
JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within ISO (PMID:12882831) RGD PMID:12882831 NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO MGI:1857191 (PMID:1830926) RGD PMID:1830926 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:12882831), (PMID:14988498) RGD PMID:12882831 PMID:14988498 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Mlh1 mutL homolog 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 NCBI chr 8:120,074,871...120,112,109
Ensembl chr 8:111,196,468...111,233,617
JBrowse link
G Msh2 mutS homolog 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:10430621)
Ensembl
RGD
PMID:10430621 GO_REF:0000107 NCBI chr 6:12,567,368...12,626,534
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Pagr1 Paxip1-associated glutamate-rich protein 1 involved_in ISO (PMID:26744420) RGD PMID:26744420 NCBI chr 1:181,622,698...181,625,024 JBrowse link
G Paxip1 PAX interacting protein 1 involved_in ISO (PMID:26744420) RGD PMID:26744420 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component involved_in ISO UniProtKB:Q9JK91 (PMID:10430621) RGD PMID:10430621 NCBI chr12:15,790,478...15,814,790
Ensembl chr12:10,676,764...10,701,066
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C acts_upstream_of_or_within ISO MGI:2181288 (PMID:9015183) RGD PMID:9015183 NCBI chr13:52,147,717...52,259,810
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Tbx21 T-box transcription factor 21 acts_upstream_of_or_within ISO MGI:2180194 (PMID:12882831) RGD PMID:12882831 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,082,322...82,098,831
JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:30842412) RGD PMID:30842412 NCBI chr 3:138,315,006...138,336,691
Ensembl chr 3:117,861,653...117,882,680
JBrowse link
G Il10 interleukin 10 acts_upstream_of ISO UniProtKB:P60568 (PMID:22962438) RGD PMID:22962438 NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO UniProtKB:P22301 (PMID:22962438) RGD PMID:22962438 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO
IEA
ISS
(PMID:11460154)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:11460154 GO_REF:0000024 GO_REF:0000107 NCBI chr14:84,604,623...84,609,707
Ensembl chr14:80,390,643...80,395,693
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20553
    immune system process 3120
      leukocyte activation 1075
        lymphocyte activation 869
          B cell activation 306
            positive regulation of B cell activation 92
              B cell costimulation 4
              positive regulation of B cell differentiation + 18
              positive regulation of B cell proliferation 49
              positive regulation of isotype switching + 31
Path 2
Term Annotations click to browse term
  biological_process 20553
    biological regulation 13833
      regulation of biological process 13387
        regulation of multicellular organismal process 3345
          positive regulation of multicellular organismal process 1895
            positive regulation of cell activation 380
              positive regulation of leukocyte activation 356
                positive regulation of lymphocyte activation 318
                  positive regulation of B cell activation 92
                    B cell costimulation 4
                    positive regulation of B cell differentiation + 18
                    positive regulation of B cell proliferation 49
                    positive regulation of isotype switching + 31
paths to the root