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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of T cell activation
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Accession:GO:0050868 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.
Synonyms:exact_synonym: down regulation of T cell activation;   downregulation of T cell activation;   negative regulation of T lymphocyte activation
 narrow_synonym: inhibition of T cell activation


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negative regulation of T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 8:66,925,650...66,944,861
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Ctsg cathepsin G involved_in ISO
IEA
ISS		 (PMID:15100291)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:15100291 GO_REF:0000024 GO_REF:0000107 NCBI chr15:33,901,230...33,907,596
Ensembl chr15:29,931,003...29,937,353 		JBrowse link
G Dusp22 dual specificity phosphatase 22 acts_upstream_of_or_within ISO (PMID:24714587) RGD PMID:24714587 NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,780,981...33,831,321 		JBrowse link
G Dusp3 dual specificity phosphatase 3 involved_in ISO
IBA		 (PMID:12447358)
GO_REF:0000033		 RGD
GO_Central		 PMID:12447358 GO_REF:0000033 NCBI chr10:87,420,213...87,434,202
Ensembl chr10:86,920,014...86,933,962 		JBrowse link
G Fgl1 fibrinogen-like 1 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:30580966)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:30580966 GO_REF:0000024 GO_REF:0000033 NCBI chr16:57,824,127...57,854,413
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 IMP RGD PMID:16584774 RGD:2303771 NCBI chr 4:79,025,151...79,031,917
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Gpnmb glycoprotein nmb involved_in ISO (PMID:19350579) RGD PMID:19350579 NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18997793) RGD PMID:18997793 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:28891065) RGD PMID:28891065 NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Ildr2 immunoglobulin-like domain containing receptor 2 involved_in ISO
IEA		 (PMID:29431694)
GO_REF:0000107		 RGD
Ensembl		 PMID:29431694 GO_REF:0000107 NCBI chr13:78,518,770...78,580,627
Ensembl chr13:78,518,802...78,576,924 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:9498750)		 BHF-UCL
RGD		 PMID:9498750 GO_REF:0000024 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Lag3 lymphocyte activating 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12421911)
GO_REF:0000107
(PMID:12209638), (PMID:30580966)		 RGD
Ensembl		 PMID:12209638 PMID:12421911 PMID:30580966 GO_REF:0000107 NCBI chr 4:159,398,930...159,407,001
Ensembl chr 4:157,712,667...157,720,404 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:18619870) RGD PMID:18619870 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lax1 lymphocyte transmembrane adaptor 1 involved_in ISO
IBA		 (PMID:12359715)
GO_REF:0000033		 RGD
GO_Central		 PMID:12359715 GO_REF:0000033 NCBI chr13:47,686,840...47,697,396
Ensembl chr13:45,134,834...45,145,381 		JBrowse link
G Mir181c microRNA 181c acts_upstream_of ISO (PMID:21112091) RGD PMID:21112091 NCBI chr19:40,888,291...40,888,396
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Mir27a microRNA 27a involved_in ISO (PMID:24725595) RGD PMID:24725595 NCBI chr19:40,859,603...40,859,689
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 involved_in IEA
ISO
IBA		 GO_REF:0000002
GO_REF:0000107
(PMID:12612075)
GO_REF:0000033		 InterPro
Ensembl
RGD
GO_Central		 PMID:12612075 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:93,842,747...93,984,314
Ensembl chr 2:92,057,216...92,069,849 		JBrowse link
G Pdcd1 programmed cell death 1 involved_in ISO (PMID:21276005), (PMID:38377992) RGD PMID:21276005 PMID:38377992 NCBI chr 9:101,866,124...101,879,278
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO
IEA		 MGI:4361448 (PMID:21874024)
GO_REF:0000107		 RGD
Ensembl		 PMID:21874024 GO_REF:0000107 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285 		JBrowse link
G Pla2g2d phospholipase A2, group IID acts_upstream_of_or_within ISO (PMID:19564598) RGD PMID:19564598 NCBI chr 5:156,299,374...156,305,816
Ensembl chr 5:151,018,870...151,022,525 		JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:21044313)
GO_REF:0000033
(PMID:18299186)		 BHF-UCL
RGD
GO_Central		 PMID:18299186 PMID:21044313 GO_REF:0000024 GO_REF:0000033 NCBI chr 2:194,055,165...194,103,209
Ensembl chr 2:191,366,808...191,414,779 		JBrowse link
G Socs6 suppressor of cytokine signaling 6 acts_upstream_of_or_within ISO (PMID:20007709) RGD PMID:20007709 NCBI chr18:84,386,587...84,413,927
Ensembl chr18:82,111,827...82,139,219 		JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO MGI:1857246 (PMID:9645617) RGD PMID:9645617 NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857258 (PMID:12646629)
GO_REF:0000107		 RGD
Ensembl		 PMID:12646629 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tigit T cell immunoreceptor with Ig and ITIM domains involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:19011627)
GO_REF:0000107
GO_REF:0000002
MGI:4939784 (PMID:21199897)
GO_REF:0000033		 RGD
Ensembl
InterPro
GO_Central		 PMID:19011627 PMID:21199897 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr11:70,534,907...70,552,452
Ensembl chr11:57,029,118...57,045,994 		JBrowse link
G Tnfaip8l2 TNF alpha induced protein 8 like 2 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:21963221)		 GO_Central
RGD		 PMID:21963221 GO_REF:0000033 NCBI chr 2:185,399,442...185,415,798
Ensembl chr 2:182,709,378...182,726,760 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
IEA
ISS		 (PMID:38377992)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:38377992 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:43,759,271...43,791,682
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:16606666)
(PMID:15585831)		 RGD PMID:15585831 PMID:16606666 NCBI chr 2:190,942,224...191,010,280
Ensembl chr 2:188,253,594...188,321,658 		JBrowse link
negative regulation of activated T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:19360123)		 Ensembl
RGD		 PMID:19360123 GO_REF:0000107 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Btn2a2 butyrophilin, subfamily 2, member A2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23589618)
GO_REF:0000107
(PMID:20208008)		 RGD
Ensembl		 PMID:20208008 PMID:23589618 GO_REF:0000107 NCBI chr17:42,048,842...42,060,650
Ensembl chr17:41,620,839...41,632,618 		JBrowse link
G Casp3 caspase 3 acts_upstream_of_or_within ISO
IEA		 MGI:2178778 (PMID:12970760)
GO_REF:0000107		 RGD
Ensembl		 PMID:12970760 GO_REF:0000107 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:12538684)
(PMID:17489864)		 RGD PMID:12538684 PMID:17489864 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO
IEA		 (PMID:18329370)
GO_REF:0000107		 RGD
Ensembl		 PMID:18329370 GO_REF:0000107 NCBI chr 8:50,237,210...50,274,472
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 acts_upstream_of_or_within ISO
IEA		 MGI:3505776 (PMID:18077788)
GO_REF:0000107		 RGD
Ensembl		 PMID:18077788 GO_REF:0000107 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (PMID:18619870) RGD PMID:18619870 NCBI chr 5:148,371,880...148,393,927
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:23817958) RGD PMID:23817958 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:19380766) RGD PMID:19380766 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Lrrc32 leucine rich repeat containing 32 acts_upstream_of_or_within ISO (PMID:18628982) RGD PMID:18628982 NCBI chr 1:152,785,709...152,802,997
Ensembl chr 1:152,786,511...152,798,373 		JBrowse link
G Mir181c microRNA 181c acts_upstream_of ISO (PMID:21112091) RGD PMID:21112091 NCBI chr19:40,888,291...40,888,396
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 involved_in ISO (PMID:12538684) RGD PMID:12538684 NCBI chr 1:236,572,497...236,637,490
Ensembl chr 1:227,158,941...227,223,938 		JBrowse link
G Prkar1a protein kinase cAMP-dependent type I regulatory subunit alpha involved_in ISO
IEA		 (PMID:17911601)
GO_REF:0000107		 RGD
Ensembl		 PMID:17911601 GO_REF:0000107 NCBI chr10:95,120,537...95,139,028
Ensembl chr10:94,620,039...94,639,041 		JBrowse link
G Prnp prion protein involved_in ISO
IEA		 (PMID:20145049)
GO_REF:0000107		 RGD
Ensembl		 PMID:20145049 GO_REF:0000107 NCBI chr 3:139,639,076...139,654,420
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO
IEA		 (PMID:18172933)
GO_REF:0000107		 RGD
Ensembl		 PMID:18172933 GO_REF:0000107 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (PMID:18329370) RGD PMID:18329370 NCBI chr 7:109,640,034...109,663,354
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
negative regulation of alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor acts_upstream_of_or_within ISO
IEA		 (PMID:10069416)
GO_REF:0000107		 RGD
Ensembl		 PMID:10069416 GO_REF:0000107 NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr20:28,824,493...28,850,175
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
negative regulation of alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gli3 GLI family zinc finger 3 involved_in ISO
IEA		 (PMID:19667090)
GO_REF:0000107		 RGD
Ensembl		 PMID:19667090 GO_REF:0000107 NCBI chr17:54,134,064...54,405,198
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO
IEA		 (PMID:19109233)
GO_REF:0000107		 RGD
Ensembl		 PMID:19109233 GO_REF:0000107 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA		 (PMID:10981962)
GO_REF:0000107		 RGD
Ensembl		 PMID:10981962 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
negative regulation of alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Btla B and T lymphocyte associated acts_upstream_of_or_within ISO MGI:3027713 (PMID:15568026) RGD PMID:15568026 NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181 		JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO
IEA		 MGI:5510586 (PMID:23487419)
GO_REF:0000107		 RGD
Ensembl		 PMID:23487419 GO_REF:0000107 NCBI chr12:6,578,266...6,582,913
Ensembl chr12:1,780,371...1,784,985 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO
IEA		 MGI:1857034 (PMID:16945588)
GO_REF:0000107		 RGD
Ensembl		 PMID:16945588 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:170,768,413...170,776,749
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (PMID:26311901) RGD PMID:26311901 NCBI chr 1:74,582,103...74,600,203
Ensembl chr 1:65,671,902...65,679,626 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO
IEA		 (PMID:17164348)
GO_REF:0000107		 RGD
Ensembl		 PMID:17164348 GO_REF:0000107 NCBI chr 9:112,979,972...113,014,315
Ensembl chr 9:105,533,136...105,567,479 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cbfb core-binding factor subunit beta involved_in ISO
IEA		 (PMID:18258917)
GO_REF:0000107		 RGD
Ensembl		 PMID:18258917 GO_REF:0000107 NCBI chr19:49,955,133...50,002,661
Ensembl chr19:33,049,172...33,092,751 		JBrowse link
G Hmgb1 high mobility group box 1 involved_in ISO (PMID:22473704) RGD PMID:22473704 NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Runx1 RUNX family transcription factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18258917)		 UniProt
RGD		 PMID:18258917 GO_REF:0000024 NCBI chr11:45,325,778...45,560,300
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Runx3 RUNX family transcription factor 3 involved_in ISO (PMID:18258917) RGD PMID:18258917 NCBI chr 5:152,644,270...152,702,835
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
negative regulation of CD4-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg2 arginase 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25009204)		 Ensembl
RGD		 PMID:25009204 GO_REF:0000107 NCBI chr 6:103,669,001...103,694,375
Ensembl chr 6:97,936,002...97,961,378 		JBrowse link
G Cblb Cbl proto-oncogene B acts_upstream_of_or_within ISO
IEA		 MGI:2180572 (PMID:14973438)
GO_REF:0000107		 RGD
Ensembl		 PMID:14973438 GO_REF:0000107 NCBI chr11:62,058,829...62,225,904
Ensembl chr11:48,592,703...48,756,839 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd44 CD44 molecule involved_in ISO (PMID:25065622) RGD PMID:25065622 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within ISO
IEA		 (PMID:17028180)
GO_REF:0000107		 RGD
Ensembl		 PMID:17028180 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase acts_upstream_of_or_within ISO
IEA		 MGI:1856404 (PMID:14973438)
GO_REF:0000107		 RGD
Ensembl		 PMID:14973438 GO_REF:0000107 NCBI chr 3:164,102,490...164,193,932
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Lgals5 galectin 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:64,351,976...64,355,137
Ensembl chr10:63,853,935...63,857,153 		JBrowse link
G Lgals9 galectin 9 involved_in ISO
IBA		 (PMID:20209097)
(PMID:25065622)
GO_REF:0000033		 RGD
GO_Central		 PMID:20209097 PMID:25065622 GO_REF:0000033 NCBI chr10:64,405,044...64,428,249
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:3695433 (PMID:17137798)
GO_REF:0000107		 RGD
Ensembl		 PMID:17137798 GO_REF:0000107 NCBI chr18:30,516,931...30,567,199
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Tarm1 T cell-interacting, activating receptor on myeloid cells 1 involved_in ISO (PMID:26311901) RGD PMID:26311901 NCBI chr 1:74,582,103...74,600,203
Ensembl chr 1:65,671,902...65,679,626 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 acts_upstream_of_or_within ISO (PMID:15568026) RGD PMID:15568026 NCBI chr 5:170,768,413...170,776,749
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Twsg1 twisted gastrulation BMP signaling modulator 1 involved_in ISO
IEA		 (PMID:17164348)
GO_REF:0000107		 RGD
Ensembl		 PMID:17164348 GO_REF:0000107 NCBI chr 9:112,979,972...113,014,315
Ensembl chr 9:105,533,136...105,567,479 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in
acts_upstream_of_or_within		 ISO (PMID:24691993)
(PMID:21383057)		 RGD PMID:21383057 PMID:24691993 NCBI chr20:28,824,493...28,850,175
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:79,781,784...79,785,440
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) RGD PMID:28813410 PMID:28813417 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Dapl1 death associated protein-like 1 involved_in ISO (PMID:35773432) RGD PMID:35773432 NCBI chr 3:64,369,734...64,389,677
Ensembl chr 3:43,960,810...43,980,940 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO UniProtKB:P04439 (PMID:24643698) RGD PMID:24643698 NCBI chr17:41,841,302...41,849,359
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a2 solute carrier family 4 member 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24515893)		 UniProt
RGD		 PMID:24515893 GO_REF:0000024 NCBI chr 4:11,628,860...11,646,961
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24880459)		 UniProt
RGD		 PMID:24880459 GO_REF:0000024 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO
IEA		 (PMID:22730529), (PMID:24880459)
GO_REF:0000107		 RGD
Ensembl		 PMID:22730529 PMID:24880459 GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
negative regulation of CD8-positive, alpha-beta T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a2 solute carrier family 4 member 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24515893)		 UniProt
RGD		 PMID:24515893 GO_REF:0000024 NCBI chr 4:11,628,860...11,646,961
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Vsir V-set immunoregulatory receptor involved_in ISO (PMID:24691993) RGD PMID:24691993 NCBI chr20:28,824,493...28,850,175
Ensembl chr20:28,281,596...28,303,878 		JBrowse link
negative regulation of cytotoxic T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:16493035) RGD PMID:16493035 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
negative regulation of establishment of T cell polarity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISO
ISS		 (PMID:23241886)
GO_REF:0000024		 RGD
UniProt		 PMID:23241886 GO_REF:0000024 NCBI chr17:40,751,771...40,975,611
Ensembl chr17:40,323,867...40,548,092 		JBrowse link
negative regulation of immature T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnrh1 gonadotropin releasing hormone 1 IMP RGD PMID:11092955 RGD:9685051 NCBI chr15:46,147,878...46,152,086
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581 		JBrowse link
negative regulation of immature T cell proliferation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:12421925)		 Ensembl
UniProt
RGD		 PMID:12421925 GO_REF:0000024 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A involved_in ISO (PMID:15964995) RGD PMID:15964995 NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO
IEA		 MGI:5510586 (PMID:23487419)
GO_REF:0000107		 RGD
Ensembl		 PMID:23487419 GO_REF:0000107 NCBI chr12:6,578,266...6,582,913
Ensembl chr12:1,780,371...1,784,985 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 acts_upstream_of_or_within ISO
IEA		 (PMID:16230479)
GO_REF:0000107		 RGD
Ensembl		 PMID:16230479 GO_REF:0000107 NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO
IEA		 (PMID:19109233)
GO_REF:0000107		 RGD
Ensembl		 PMID:19109233 GO_REF:0000107 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Tmem131l transmembrane 131 like involved_in ISO
IEA		 (PMID:23690469)
GO_REF:0000107		 RGD
Ensembl		 PMID:23690469 GO_REF:0000107 NCBI chr 2:171,555,673...171,689,774
Ensembl chr 2:169,258,289...169,391,711 		JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO
IEA		 MGI:3582343 (PMID:29341118)
GO_REF:0000107		 RGD
Ensembl		 PMID:29341118 GO_REF:0000107 NCBI chr 4:14,602,762...14,608,405
Ensembl chr 4:13,710,575...13,716,207 		JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:92,926,184...92,927,830
Ensembl chr 1:83,798,703...83,800,235 		JBrowse link
negative regulation of NK T cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:10540326) RGD PMID:10540326 NCBI chr10:100,428,826...100,441,693
Ensembl chr10:99,929,801...99,942,674 		JBrowse link
G Lgals3 galectin 3 involved_in IEA
ISO		 GO_REF:0000107
(PMID:26582946)		 Ensembl
RGD		 PMID:26582946 GO_REF:0000107 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
negative regulation of NK T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zbtb7b zinc finger and BTB domain containing 7B involved_in ISO
IEA		 (PMID:23105140)
GO_REF:0000107		 RGD
Ensembl		 PMID:23105140 GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:22080863)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22080863 GO_REF:0000024 GO_REF:0000107 NCBI chr18:63,498,890...63,564,571
Ensembl chr18:61,229,014...61,294,627 		JBrowse link
negative regulation of regulatory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd44 CD44 molecule involved_in ISO (PMID:25065622) RGD PMID:25065622 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 involved_in ISO
IEA
IBA		 (PMID:18641304)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:18641304 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Irf1 interferon regulatory factor 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18641303)		 UniProt
RGD		 PMID:18641303 GO_REF:0000024 NCBI chr10:38,417,935...38,424,946
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Lag3 lymphocyte activating 3 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15485628)		 UniProt
Ensembl
RGD		 PMID:15485628 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:159,398,930...159,407,001
Ensembl chr 4:157,712,667...157,720,404 		JBrowse link
G Mdk midkine involved_in ISO
IEA
ISS		 (PMID:22323540)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:22323540 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:98,356,789...98,358,960
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Mir21 microRNA 21 involved_in ISO RNAcentral:URS0000338542_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir30b microRNA 30b involved_in ISO RNAcentral:URS000039ED8D_9606 (PMID:22387553) RGD PMID:22387553 NCBI chr 7:102,021,543...102,021,629
Ensembl chr 7:100,132,589...100,132,675 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO
IEA		 (PMID:18713990)
GO_REF:0000107		 RGD
Ensembl		 PMID:18713990 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Tug1 taurine up-regulated 1 IMP RGD PMID:30287503 RGD:38549580 NCBI chr14:82,743,501...82,750,534
Ensembl chr14:78,522,506...78,526,927 		JBrowse link
negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:26492563) RGD PMID:26492563 NCBI chr10:31,383,801...31,415,334
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Lgals3 galectin 3 involved_in ISO (PMID:19706535) RGD PMID:19706535 NCBI chr15:23,099,795...23,111,731
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
negative regulation of T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd74 CD74 molecule acts_upstream_of_or_within ISO MGI:1927205 (PMID:7679955) RGD PMID:7679955 NCBI chr18:56,527,071...56,536,406
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 acts_upstream_of_or_within ISO
IEA		 (PMID:12794108)
GO_REF:0000107		 RGD
Ensembl		 PMID:12794108 GO_REF:0000107 NCBI chr12:41,510,252...41,541,433
Ensembl chr12:35,849,617...35,880,838 		JBrowse link
G Ifnb1 interferon beta 1 involved_in ISO (PMID:20554961) RGD PMID:20554961 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:92,926,184...92,927,830
Ensembl chr 1:83,798,703...83,800,235 		JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein acts_upstream_of_or_within ISO
IEA		 (PMID:12794108)
GO_REF:0000107		 RGD
Ensembl		 PMID:12794108 GO_REF:0000107 NCBI chr 3:28,390,745...28,393,299
Ensembl chr 3:7,992,552...7,995,133 		JBrowse link
G Prdx2 peroxiredoxin 2 acts_upstream_of_or_within ISO MGI:2668456 (PMID:16290204) RGD PMID:16290204 NCBI chr19:40,085,788...40,091,083
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
negative regulation of T cell differentiation in thymus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 involved_in ISO
IEA		 (PMID:12421925)
GO_REF:0000107		 RGD
Ensembl		 PMID:12421925 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Foxj1 forkhead box J1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:16339515)		 Ensembl
RGD		 PMID:16339515 GO_REF:0000107 NCBI chr10:102,065,163...102,069,945
Ensembl chr10:101,566,304...101,570,237 		JBrowse link
G Ihh Indian hedgehog signaling molecule involved_in ISO
IEA		 (PMID:19109233)
GO_REF:0000107		 RGD
Ensembl		 PMID:19109233 GO_REF:0000107 NCBI chr 9:83,952,986...83,959,203
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Nfkbid NFKB inhibitor delta acts_upstream_of_or_within ISO (PMID:11931770) RGD PMID:11931770 NCBI chr 1:94,808,459...94,824,726
Ensembl chr 1:85,680,861...85,690,447 		JBrowse link
G Rag2 recombination activating 2 IMP RGD PMID:30206106 RGD:38508903 NCBI chr 3:108,357,399...108,367,186
Ensembl chr 3:87,902,238...87,911,066 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA		 (PMID:10981962)
GO_REF:0000107		 RGD
Ensembl		 PMID:10981962 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Zc3h8 zinc finger CCCH type containing 8 involved_in ISO
IEA		 (PMID:12153508)
GO_REF:0000107		 RGD
Ensembl		 PMID:12153508 GO_REF:0000107 NCBI chr 3:136,629,998...136,646,998
Ensembl chr 3:116,176,798...116,193,787 		JBrowse link
negative regulation of T cell homeostatic proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule acts_upstream_of_or_within ISO MGI:2179996 (PMID:16769998) RGD PMID:16769998 NCBI chr20:48,655,549...48,661,786
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
negative regulation of T cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 involved_in ISO
IEA		 (PMID:16709924)
GO_REF:0000107		 RGD
Ensembl		 PMID:16709924 GO_REF:0000107 NCBI chr 1:22,295,093...22,307,720
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Btla B and T lymphocyte associated acts_upstream_of_or_within
involved_in		 ISO MGI:3027713 (PMID:12796776)
(PMID:15568026)		 RGD PMID:12796776 PMID:15568026 NCBI chr11:55,563,683...55,588,187
Ensembl chr11:55,564,899...55,587,181 		JBrowse link
G Cd274 CD274 molecule acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:17016562)
GO_REF:0000033		 RGD
GO_Central		 PMID:17016562 GO_REF:0000033 NCBI chr 1:236,526,215...236,549,956
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd276 Cd276 molecule acts_upstream_of_or_within ISO MGI:3033707 (PMID:12925852) RGD PMID:12925852 NCBI chr 8:67,833,587...67,863,918
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cd37 CD37 molecule acts_upstream_of_or_within ISO MGI:1350360 (PMID:20709950) RGD PMID:20709950 NCBI chr 1:104,855,622...104,861,111
Ensembl chr 1:95,719,190...95,724,648 		JBrowse link
G Cd80 Cd80 molecule involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:75,760,073...75,798,978
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd86 CD86 molecule involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr11:77,647,565...77,706,178
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:17081782) RGD PMID:17081782 NCBI chr 1:90,171,401...90,187,810
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:16585579)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:16585579 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Clec4g C-type lectin domain family 4, member G acts_upstream_of_or_within ISO
IEA		 (PMID:19632227)
GO_REF:0000107		 RGD
Ensembl		 PMID:19632227 GO_REF:0000107 NCBI chr12:6,578,266...6,582,913
Ensembl chr12:1,780,371...1,784,985 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IMP RGD PMID:15849541 RGD:2302005 NCBI chr 9:69,812,859...69,819,959
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Dlg1 discs large MAGUK scaffold protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:3699270 (PMID:17724087)
GO_REF:0000107		 RGD
Ensembl		 PMID:17724087 GO_REF:0000107 NCBI chr11:82,416,853...82,607,797
Ensembl chr11:68,911,883...69,102,689 		JBrowse link
G Dlg5 discs large MAGUK scaffold protein 5 involved_in ISO (PMID:28169360) RGD PMID:28169360 NCBI chr15:75,786...209,735
Ensembl chr15:75,786...187,837 		JBrowse link
G Foxj1 forkhead box J1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:14963332)		 Ensembl
RGD		 PMID:14963332 GO_REF:0000107 NCBI chr10:102,065,163...102,069,945
Ensembl chr10:101,566,304...101,570,237 		JBrowse link
G Foxp3 forkhead box P3 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:15466453), (PMID:21458306), (PMID:23169781)
GO_REF:0000107
MGI:1857034 (PMID:16203996), (PMID:16769892)		 RGD
Ensembl		 PMID:15466453 PMID:16203996 PMID:16769892 PMID:21458306 PMID:23169781 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Glmn glomulin, FKBP associated protein involved_in ISO
IEA		 (PMID:12604780)
GO_REF:0000107		 RGD
Ensembl		 PMID:12604780 GO_REF:0000107 NCBI chr14:2,332,052...2,375,366
Ensembl chr14:2,187,642...2,230,420 		JBrowse link
G Gpnmb glycoprotein nmb involved_in ISO (PMID:19350579) RGD PMID:19350579 NCBI chr 4:79,341,128...79,362,366
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:14556006) RGD PMID:14556006 NCBI chr10:31,383,801...31,415,334
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 acts_upstream_of_or_within ISO
IEA		 MGI:3505776 (PMID:18077788)
GO_REF:0000107		 RGD
Ensembl		 PMID:18077788 GO_REF:0000107 NCBI chr16:74,133,259...74,145,328
Ensembl chr16:67,430,578...67,442,730 		JBrowse link
G Il20rb interleukin 20 receptor subunit beta acts_upstream_of_or_within ISO MGI:3830304 (PMID:19124723) RGD PMID:19124723 NCBI chr 8:109,858,108...109,896,066
Ensembl chr 8:100,980,383...101,009,942 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha acts_upstream_of_or_within ISO
IEA		 MGI:1857192 (PMID:12702495)
GO_REF:0000107		 RGD
Ensembl		 PMID:12702495 GO_REF:0000107 NCBI chr17:71,759,802...71,808,475
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:17356132) RGD PMID:17356132 NCBI chr 1:104,435,540...104,461,049
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Kng2 kininogen 2 IDA unstimulated Jurkat cells; ConA- or PHA-stimulated, but not IL-2 stimulated, Jurkat cells RGD PMID:16140359 RGD:1600541 NCBI chr11:91,418,470...91,440,841
Ensembl chr11:77,909,612...78,002,971 		JBrowse link
G Lilrb4 leukocyte immunoglobulin like receptor B4 involved_in ISO (PMID:17163451) RGD PMID:17163451 NCBI chr 1:78,847,685...78,853,294
Ensembl chr 1:69,805,250...69,810,660 		JBrowse link
G Mad1l1 mitotic arrest deficient 1 like 1 acts_upstream_of_or_within ISO
IEA		 (PMID:11313860)
GO_REF:0000107		 RGD
Ensembl		 PMID:11313860 GO_REF:0000107 NCBI chr12:19,434,782...19,744,574
Ensembl chr12:14,320,892...14,630,703 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 acts_upstream_of_or_within ISO MGI:3530008 (PMID:15670816) RGD PMID:15670816 NCBI chr 3:65,090,640...65,128,768
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Pawr pro-apoptotic WT1 regulator acts_upstream_of_or_within ISO MGI:2678021 (PMID:12970181) RGD PMID:12970181 NCBI chr 7:45,531,480...45,611,492
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:11224527), (PMID:17016562)
GO_REF:0000033		 RGD
GO_Central		 PMID:11224527 PMID:17016562 GO_REF:0000033 NCBI chr 1:236,572,497...236,637,490
Ensembl chr 1:227,158,941...227,223,938 		JBrowse link
G Pde5a phosphodiesterase 5A acts_upstream_of_or_within ISO (PMID:17101732) RGD PMID:17101732 NCBI chr 2:213,542,822...213,687,638
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO
IEA		 MGI:4361448 (PMID:21874024)
GO_REF:0000107		 RGD
Ensembl		 PMID:21874024 GO_REF:0000107 NCBI chr14:99,455,970...99,510,474
Ensembl chr14:95,254,589...95,308,285
Ensembl chr 1:95,254,589...95,308,285 		JBrowse link
G Pla2g2a phospholipase A2 group IIA NOT|acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:19564598)
GO_REF:0000033		 RGD
GO_Central		 PMID:19564598 GO_REF:0000033 NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g2d phospholipase A2, group IID acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:19564598)
GO_REF:0000033		 RGD
GO_Central		 PMID:19564598 GO_REF:0000033 NCBI chr 5:156,299,374...156,305,816
Ensembl chr 5:151,018,870...151,022,525 		JBrowse link
G Pla2g2f phospholipase A2, group IIF acts_upstream_of_or_within
involved_in		 ISO
IBA		 (PMID:16931517)
GO_REF:0000033		 RGD
GO_Central		 PMID:16931517 GO_REF:0000033 NCBI chr 5:156,270,077...156,276,464
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:156,324,628...156,393,065
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Pten phosphatase and tensin homolog acts_upstream_of_or_within ISO MGI:1857936 (PMID:16027169) RGD PMID:16027169 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in ISO
IEA		 (PMID:15568026)
GO_REF:0000107		 RGD
Ensembl		 PMID:15568026 GO_REF:0000107 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 acts_upstream_of_or_within ISO
IEA		 MGI:1856073|MGI:1856074 (PMID:9064344)
GO_REF:0000107		 RGD
Ensembl		 PMID:9064344 GO_REF:0000107 NCBI chr 4:159,212,320...159,237,069
Ensembl chr 4:157,526,035...157,550,984 		JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 involved_in ISO (PMID:27556504) RGD PMID:27556504 NCBI chr17:40,751,771...40,975,611
Ensembl chr17:40,323,867...40,548,092 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:20195504) RGD PMID:20195504 NCBI chr20:4,872,720...4,876,425 JBrowse link
G RT1-Ba RT1 class II, locus Ba IDA RGD PMID:9834080 RGD:5147666 NCBI chr20:4,577,057...4,581,650
Ensembl chr20:4,575,134...4,579,744 		JBrowse link
G RT1-Bb RT1 class II, locus Bb IDA RGD PMID:9834080 RGD:5147666 NCBI chr20:4,598,475...4,604,118
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:15795121) RGD PMID:15795121 NCBI chr20:4,550,594...4,560,182
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 involved_in ISO (PMID:20702625) RGD PMID:20702625 NCBI chr20:1,329,227...1,333,394
Ensembl chr20:1,287,521...1,328,117 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 acts_upstream_of_or_within ISO
IEA		 (PMID:15356574)
GO_REF:0000107		 RGD
Ensembl		 PMID:15356574 GO_REF:0000107 NCBI chr 1:215,406,138...215,409,686
Ensembl chr 1:205,977,060...205,980,610 		JBrowse link
G Sdc4 syndecan 4 involved_in ISO
IEA		 (PMID:19350579)
GO_REF:0000107		 RGD
Ensembl		 PMID:19350579 GO_REF:0000107 NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
G Sftpd surfactant protein D IDA RGD PMID:9794387 RGD:4144057 NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA		 (PMID:10981962)
GO_REF:0000107		 RGD
Ensembl		 PMID:10981962 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Spn sialophorin involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(PMID:17638845)
MGI:1857246 (PMID:15117976), (PMID:7566153), (PMID:9645617)		 UniProt
RGD		 PMID:7566153 PMID:9645617 PMID:15117976 PMID:17638845 GO_REF:0000024 NCBI chr 1:191,177,449...191,190,115
Ensembl chr 1:181,746,429...181,759,628 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO
IEA		 MGI:3719583 (PMID:17481928)
GO_REF:0000107		 RGD
Ensembl		 PMID:17481928 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 involved_in ISO (PMID:15568026) RGD PMID:15568026 NCBI chr 5:170,768,413...170,776,749
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Tnfrsf21 TNF receptor superfamily member 21 involved_in ISS
IEA
ISO
IBA		 GO_REF:0000024
GO_REF:0000107
(PMID:11485735)
GO_REF:0000033		 UniProt
Ensembl
RGD
GO_Central		 PMID:11485735 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:17,879,156...17,954,085 		JBrowse link
G Tsc2 TSC complex subunit 2 acts_upstream_of_or_within ISO MGI:109583 (PMID:16027169) RGD PMID:16027169 NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951 		JBrowse link
G Tspan32 tetraspanin 32 acts_upstream_of_or_within ISO MGI:88330 (PMID:20709950) RGD PMID:20709950 NCBI chr 1:207,619,566...207,633,885
Ensembl chr 1:198,190,164...198,204,445 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 GO_REF:0000033
GO_REF:0000002
(PMID:17016562)		 GO_Central
InterPro
RGD		 PMID:17016562 GO_REF:0000002 GO_REF:0000033 NCBI chr  X:65,154,422...65,179,708
Ensembl chr  X:61,144,928...61,170,212 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 involved_in ISO (PMID:16606666) RGD PMID:16606666 NCBI chr 2:190,942,224...191,010,280
Ensembl chr 2:188,253,594...188,321,658 		JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D acts_upstream_of_or_within ISO MGI:5588370 (PMID:24415781) RGD PMID:24415781 NCBI chr 1:2,313,110...2,348,820
Ensembl chr 1:2,314,324...2,348,819 		JBrowse link
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Xcl1 X-C motif chemokine ligand 1 involved_in ISO (PMID:10887101) RGD PMID:10887101 NCBI chr13:79,781,784...79,785,440
Ensembl chr13:77,248,717...77,252,329 		JBrowse link
negative regulation of T-helper 1 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO
IEA		 (PMID:24463518)
GO_REF:0000107		 RGD
Ensembl		 PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:198,148,999...198,151,406 		JBrowse link
G Il4r interleukin 4 receptor acts_upstream_of_or_within ISO MGI:96109 (PMID:16424184) RGD PMID:16424184 NCBI chr 1:189,545,739...189,570,639
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16020505)		 BHF-UCL
RGD		 PMID:16020505 GO_REF:0000024 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO
IEA		 (PMID:9670042)
GO_REF:0000107		 RGD
Ensembl		 PMID:9670042 GO_REF:0000107 NCBI chr13:76,256,654...76,280,133
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
negative regulation of T-helper 17 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO
IEA		 (PMID:24463518)
GO_REF:0000107		 RGD
Ensembl		 PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:198,148,999...198,151,406 		JBrowse link
G Foxp3 forkhead box P3 involved_in ISO
IEA		 (PMID:23169781)
GO_REF:0000107		 RGD
Ensembl		 PMID:23169781 GO_REF:0000107 NCBI chr  X:17,580,380...17,601,181
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Il2 interleukin 2 involved_in ISO RNAcentral:URS000039ED8D_10090 (PMID:25642768) RGD PMID:25642768 NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within ISO (PMID:18792410) RGD PMID:18792410 NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Pf4 platelet factor 4 IDA RGD PMID:24986443 RGD:329901907 NCBI chr14:17,582,477...17,583,392
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Rc3h1 ring finger and CCCH-type domains 1 involved_in ISO
IEA		 (PMID:25282160)
GO_REF:0000107		 RGD
Ensembl		 PMID:25282160 GO_REF:0000107 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
G Rc3h2 ring finger and CCCH-type domains 2 involved_in ISO (PMID:25282160) RGD PMID:25282160 NCBI chr 3:41,531,319...41,596,496
Ensembl chr 3:21,110,679...21,179,933 		JBrowse link
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(PMID:25642768)		 Ensembl
RGD		 PMID:25642768 GO_REF:0000107 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO
IEA		 (PMID:21151104)
GO_REF:0000107		 RGD
Ensembl		 PMID:21151104 GO_REF:0000107 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Zbtb7b zinc finger and BTB domain containing 7B acts_upstream_of_or_within ISO
IEA		 MGI:3530739 (PMID:23034280)
GO_REF:0000107		 RGD
Ensembl		 PMID:23034280 GO_REF:0000107 NCBI chr 2:177,093,569...177,111,894
Ensembl chr 2:174,797,453...174,814,236 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:25282160)		 UniProt
Ensembl
RGD		 PMID:25282160 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
negative regulation of T-helper 17 cell lineage commitment term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd69 Cd69 molecule involved_in ISO (PMID:24752896) RGD PMID:24752896 NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:162,725,446...162,733,542 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (PMID:20696842) RGD PMID:20696842 NCBI chr16:18,418,807...18,432,515
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Lgals1 galectin 1 involved_in ISO
IEA		 (PMID:24752896)
GO_REF:0000107		 RGD
Ensembl		 PMID:24752896 GO_REF:0000107 NCBI chr 7:112,365,695...112,368,801
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Loxl3 lysyl oxidase-like 3 involved_in ISO (PMID:28065600) RGD PMID:28065600 NCBI chr 4:117,098,358...117,114,673
Ensembl chr 4:115,540,685...115,557,466 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A involved_in ISO
IEA		 (PMID:20696842)
GO_REF:0000107		 RGD
Ensembl		 PMID:20696842 GO_REF:0000107 NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Tbx21 T-box transcription factor 21 involved_in ISO
IEA		 (PMID:21151104)
GO_REF:0000107		 RGD
Ensembl		 PMID:21151104 GO_REF:0000107 NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Tnfsf18 TNF superfamily member 18 involved_in ISO (PMID:24107315) RGD PMID:24107315 NCBI chr13:76,366,790...76,440,673
Ensembl chr13:73,831,252...73,843,169 		JBrowse link
negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:17008549)		 UniProt
Ensembl
RGD		 PMID:17008549 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 involved_in ISO
IEA		 (PMID:24463518)
GO_REF:0000107		 RGD
Ensembl		 PMID:24463518 GO_REF:0000107 NCBI chr 1:207,578,447...207,665,126
Ensembl chr 1:198,148,999...198,151,406 		JBrowse link
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO
IEA		 MGI:96559 (PMID:12594267)
GO_REF:0000107		 RGD
Ensembl		 PMID:12594267 GO_REF:0000107 NCBI chr11:90,358,753...90,382,049
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Hlx H2.0-like homeobox acts_upstream_of_or_within ISO
IEA		 MGI:105367|MGI:2182089 (PMID:16424184)
GO_REF:0000107		 RGD
Ensembl		 PMID:16424184 GO_REF:0000107 NCBI chr13:98,811,852...98,817,264
Ensembl chr13:96,280,339...96,285,750 		JBrowse link
G Socs5 suppressor of cytokine signaling 5 involved_in ISO (PMID:12242343) RGD PMID:12242343 NCBI chr 6:13,235,157...13,266,161
Ensembl chr 6:7,481,095...7,514,834 		JBrowse link
G Zfp35 zinc finger protein 35 acts_upstream_of_or_within IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr18:15,543,604...15,559,084
Ensembl chr18:15,268,814...15,285,088 		JBrowse link
negative regulation of T-helper cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rc3h1 ring finger and CCCH-type domains 1 acts_upstream_of_or_within ISO
IEA		 MGI:3581675 (PMID:15917799)
GO_REF:0000107		 RGD
Ensembl		 PMID:15917799 GO_REF:0000107 NCBI chr13:75,707,098...75,779,114
Ensembl chr13:73,173,946...73,238,839 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    negative regulation of biological process 5837
      negative regulation of immune system process 591
        negative regulation of leukocyte activation 223
          negative regulation of lymphocyte activation 192
            negative regulation of T cell activation 152
              negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2
              negative regulation of T cell differentiation + 60
              negative regulation of T cell proliferation + 86
              negative regulation of alpha-beta T cell activation + 53
              negative regulation of establishment of T cell polarity 1
              negative regulation of gamma-delta T cell activation + 0
Path 2
Term Annotations click to browse term
  biological_process 20558
    biological regulation 13833
      regulation of biological process 13394
        regulation of cellular process 13030
          regulation of cell activation 667
            regulation of leukocyte activation 609
              regulation of lymphocyte activation 525
                regulation of T cell activation 386
                  negative regulation of T cell activation 152
                    negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell 2
                    negative regulation of T cell differentiation + 60
                    negative regulation of T cell proliferation + 86
                    negative regulation of alpha-beta T cell activation + 53
                    negative regulation of establishment of T cell polarity 1
                    negative regulation of gamma-delta T cell activation + 0
paths to the root